Clinical trials: Traumatic Injury of Spine
Intubation;Difficult, Cervical Spinal Cord Injury
C-MAC Videolaryngoscope Intubation and Cervical Spine Motion
The aim of the study is to compare the effect of the C-MAC videolaryngoscope intubation technique vs. the conventional direct laryngoscope intubation technique on the cervical spine motion during intubation in patients with the…
- Trial name
- NCT03567902
- Testing
- C-MAC videolaryngoscope intubation, Direct laryngoscope intubation
- Volunteers
- 20 people
- Sponsor
- Seoul National University Hospital
Spine Disease, Neurological Disorder
EMG and SSEP Device (EPAD® 2.0) for Intraoperative Monitoring of Patient Undergoing Spinal Nerve Spine Surgery
In patients undergoing spine surgery, spinal nerve roots and spinal cord are vulnerable to surgical insults especially for instrumentation and may lead to long term sequelae.
- Trial name
- NCT03848377
- Volunteers
- 30 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Injury of Cervical Spine, Cervical Spine Fractures
Prospective Pilot Study Validating the Canadian C-Spine Rule Pre-hospital
This study is designed to evaluate the safety, level of performance and level of comfort with the Canadian C-Spine rule in a prehospital setting by emergency medicine undergraduates.
- Trial name
- NCT01278511
- Testing
- Canadian C-Spine rule
- Where
- Belgium
- Sponsor
- KU Leuven
Lumbar Spine Stenosis, Lumbar Disc Herniation
Dynamic Compliance-Guided Ventilation in Lumbar Surgery
Postoperative pulmonary complications are a frequent cause of morbidity following lumbar stabilization surgery. Conventional ventilation strategies may not adequately reflect intraoperative changes in respiratory mechanics…
- Conditions
- Lumbar Spine Stenosis, Lumbar Disc Herniation, Ventilator-Induced Lung Injury, Postoperative Complications
- Trial name
- NCT07349719
- Testing
- Dynamic Compliance Guided Ventilation, Standard Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ankara City Hospital Bilkent
Multiple Trauma, Traumatic Brain Injury
Spinal Clearance Study: Expediting the Spinal Clearance Process in the Major Trauma Patient
The Alfred Hospital receives approximately 40% of the major trauma patients in Victoria, all of whom are at risk for spinal injuries.
- Conditions
- Multiple Trauma, Traumatic Brain Injury, Spinal Injuries
- Trial name
- NCT00163826
- Where
- Australia
- Volunteers
- 299 people
- Sponsor
- Bayside Health
Osteoporotic Fractures, Spinal Fractures
Build Better Bones With Exercise
The long-term goal of our research team is to conduct a large multicentre study to evaluate whether tailored home exercise can prevent fractures in high-risk individuals.
- Trial name
- B3E (NCT01761084)
- Testing
- Exercise and behaviour change strategies
- Where
- Canada
- Volunteers
- 141 people
- Sponsor
- University of Waterloo
Spinal Cord Injury, Spinal Cord Injuries
Testosterone Therapy With or Without Finasteride After Spinal Cord Injury: TRT-SCI Trial
Spinal cord injury (SCI) results in lower limb muscle loss, bone loss, and high fat mass that impede the recovery of physical function, increase bone fracture risk, and worsen health and quality of life.
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Injuries, Spinal Cord, Spinal Cord Contusion
- Trial name
- TRT-SCI (NCT07742553)
- Testing
- testosterone cypionate, finasteride
- Where
- 4 sites in United States
- Volunteers
- 300 people
- Sponsor
- VA Office of Research and Development
Cervical Injury Spine
Subaxial Cervical Traumatic Injuries
The aim of this study is to assess the mid-term outcomes of treating subaxial cervical traumatic injury cases admitted to the Trauma Unit of Assiut University Hospital.
- Trial name
- NCT06297395
- Volunteers
- 100 people
- Sponsor
- Assiut University
Osteoporosis
Quantitative Diffusion and Fat Imaging of the Spine
Primary Objective: The purpose of this study is to determine whether or not combined quantitative diffusion and fat MR imaging techniques can differentiate between benign and malignant vertebral fractures.
- Trial name
- NCT00498277
- Testing
- Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- M.D. Anderson Cancer Center
Osteoporosis, Vertebral Fractures
The Effect of Exercise on Physical Function in Older Women With Osteoporosis and a History of Vertebral Fracture
The study is a parallel-group single blinded randomized controlled trial, examining the effect of exercise on physical function in older women with osteoporosis and a history of vertebral fracture.
- Trial name
- NCT02781974
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 149 people
- Sponsor
- Oslo Metropolitan University
Spine Fusion, Spine Injury
Spine Surgery Video Observation Study. The Creation of a Benchmark Video (RGB-Depth) Dataset to Investigate the Feasibility of Developing a Markerless Tracking System for Spine Surgery.
The primary study objective is to build a video dataset, consisting of both colour and depth information, of spine surgery that includes both 'open' and 'minimally invasive' (MIS) surgeries.
- Conditions
- Spine Fusion, Spine Injury, Spine Degeneration, Navigation, Spatial
- Trial name
- SPIVOS (NCT06580379)
- Testing
- Spine surgery
- Volunteers
- 25 people
- Sponsor
- Imperial College London
Infection, Spinal Injuries
The Value of Home Chlorhexidine Pre-Surgical Wash Before Spine Surgery
The study team hypothesizes that at-home cleansing of the surgical site with chlorhexidine wipes provide no added benefit to decreasing microbial activity or preventing surgical site infections.
- Trial name
- NCT02767427
- Testing
- Chlorhexidine Wipes, No intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Columbia University
Neck Injuries
Evaluation of Comfort in a Spinal Collar
This is an observational study which aims to assess the comfort of a spinal collar in patients who have them fitted as part of their clinical care due to neck injury.
- Trial name
- NCT04066686
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- Imperial College Healthcare NHS Trust
Injuries, Spinal Cord
Assessment of Neurorehabilitation in Spinal Cord Injury Using Neuroimage Tools.
The sensorimotor cortex may play a role in the functional recovery after Spinal Cord Injury (SCI) through efference generated in the absence of the afference.
- Trial name
- NCT03914456
- Testing
- rehabilitation treatment
- Volunteers
- 7 people
- Sponsor
- Universidade do Vale do Paraíba
Traumatic Injuries, Traumatic Injury of Spine
Human Impact Exposure Onboard High-Speed Boats
Operating high-speed boats is dangerous. The purpose of this study is to establish what levels and what characteristics of impact exposure cause injuries.
- Conditions
- Traumatic Injuries, Traumatic Injury of Spine, Traumatic Head Injury
- Trial name
- MASHIEN (NCT05299736)
- Where
- Sweden
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Wounds and Injuries
C-Spine Movement - Shikani Optical Scope vs Macintosh Laryngoscope for Patients With Cervical Spine Injury
Patients undergoing surgery will have laryngoscopy performed using two widely accepted techniques - Macintosh Laryngoscope and Shikani Optical Scope.
- Trial name
- NCT00310999
- Testing
- Shikani Optical Stylet
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Spinal Fractures
Evaluation of Fracture Fixation With Energy and Cement in Tumors of the Spine
The objective of the clinical trial is to evaluate the SPACE 360 Delivery System using SPACE CpsXL Bone Cement compared to standard vertebroplasty in the treatment of pathological fractures of the spine caused by metastatic…
- Trial name
- EFFECTS (NCT00594321)
- Testing
- SPACE CpsXL Bone Cement and SPACE 360 Delivery System, standard vertebroplasty
- Where
- United States
- Sponsor
- University of California, Davis
Osteoporosis, Vertebral Fracture
Treatment With a Spinal Orthosis Compared to Equipment Group Training and a Control Group
Background: Back pain and osteoporosis with vertebral fractures are common conditions in elderly women and significantly affect their quality of life. A common complication of osteoporosis are vertebral fractures.
- Conditions
- Osteoporosis, Vertebral Fracture, Back Pain, Elderly Women
- Trial name
- NCT03263585
- Testing
- Spinal orthosis Spinomed, Equipment training
- Where
- 2 sites in Sweden
- Volunteers
- 113 people
- Sponsor
- Helena Salminen
Multiple Myeloma, Vertebral Fracture
Vertebral Fat Quantitative MRI as a Marker of Bone Fragility in Multiple Myeloma (MYELOMEFRAGIQUANTI)
Multiple myeloma is a disease that causes increased bone fragility which is often revealed or complicated by vertebral fractures. Invasion of bone marrow by tumor plasma cells leads to bone destruction and reduced fat fraction.
- Trial name
- NCT04609150
- Testing
- Bone marrow fat quantification by MRI
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Spinal Cord Neoplasms, Spinal Fractures
The Development of a Vertebra Localizing Aid Medical Device
The current method of incision localization in many surgical procedures requires a doctor to reference a medical image, such as an X-ray, to judge where on the body an incision should be made.
- Trial name
- NCT02603874
- Testing
- Target Tape
- Volunteers
- 100 people
- Sponsor
- Target Tape