Clinical trials: Traumatic Spinal Cord Injury
Stroke, Incomplete Spinal Cord Injury
Comparing the Ceriter Stride One, a Pressure-sensitive Smart Insole, With Gait Parameters Measured on the GRAIL in Neurological Populations
Ceriter Stride-One soles have been available on the market for several years. One of the features of these soles is that they can measure gait parameters while patients walk around in a functional environment.
- Conditions
- Stroke, Incomplete Spinal Cord Injury, Traumatic Brain Injury, Acquired Brain Injury
- Trial name
- NCT07237386
- Testing
- Wearing smart insoles
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Ghent
Spinal Cord Injury, Acute, Neurogenic Bladder
Sacral Nerve Stimulation in Improving Bladder Function After Acute Traumatic Spinal Cord Injury
The purpose of this study is to see what effects sacral neuromodulation has on bladder function and quality of life in patients with acute spinal cord injury.
- Conditions
- Spinal Cord Injury, Acute, Neurogenic Bladder, Incontinence, Urinary Tract Infections
- Trial name
- NCT03083366
- Testing
- PrimeAdvanced Surescan 97702 Neurostimulator - Medtronic (Minneapolis, MN)
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- University of Utah
Spasticity, Muscle, Spinal Cord Injuries
Long-term Efficacy of Spasticity-correcting Surgery and Botulinum Toxin Injections for Upper Limb Spasticity Treatment
Spasticity - a variety of motor over-activity and part of the upper motor neuron syndrome - is a common cause of impaired motor function after brain injuries of different etiologies.
- Conditions
- Spasticity, Muscle, Spinal Cord Injuries, Traumatic Brain Injury, Stroke
- Trial name
- NCT03910101
- Testing
- Hand surgery and intensive rehabilitation
- Where
- Sweden
- Volunteers
- 34 people
- Sponsor
- Vastra Gotaland Region
Acute Spinal Cord Injury
Mean Arterial Blood Pressure Treatment for Acute Spinal Cord Injury
Current guidelines for the clinical management of acute spinal cord injury (SCI) recommend maintenance of mean arterial blood pressure (MAP) at 85 to 90 mmHg for the first seven days after SCI as a clinical option.
- Trial name
- MAPS (NCT02232165)
- Testing
- Hypotension avoidance, Induced hypertension
- Where
- 2 sites in United States, Canada
- Volunteers
- 17 people
- Sponsor
- University of Calgary
Pediatric ALL, Spinal Cord Injuries
Spinal Cord Injury in the Pediatric Population - an International Multicenter Study
INTRODUCTION: Due to the low incidence of pediatric spinal cord injury (SCI) and the high demand for knowledge and research, international cooperation is needed to build a solid and shared understanding of the extent of the…
- Trial name
- SINpedSCI (NCT04117854)
- Where
- 11 sites in United States, Australia and 6 more
- Volunteers
- 30 people
- Sponsor
- Sunnaas Rehabilitation Hospital
Spinal Cord Injuries
Motor, Sensory, and Autonomic Function in Traumatic Spinal Cord Injury After the LION Procedure.
Possover pioneered a minimally invasive and fully reversible laparoscopic technique, laparoscopic implantation of neuroprosthesis (LION), for precise placement of an implantable pulse generator and one to four leads for…
- Trial name
- SCI-LION (NCT03441256)
- Testing
- LION procedure, NMES
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Spinal Cord Injury Centre of Western Denmark
Spinal Tumor, Traumatic Injury of Spine
Study to Evaluate the Safety and Clinical Outcome of Using Navigation System in Pedicle Screw Placement in Spine Surgery
The research project is testing whether in screw insertion of spine surgery using "Anatase" Spine Surgery Navigation System is at least as safe and accurate as using O-arm assisted spine surgery- Medtronic Stealthstation S7…
- Conditions
- Spinal Tumor, Traumatic Injury of Spine, Degenerative Spine Disease
- Trial name
- NCT04578691
- Testing
- "Anatase" Spine Surgery Navigation System, Medtronic Stealthstation S7 Treatment Guidance System
- Where
- Taiwan
- Volunteers
- 55 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Traumatic Injury of the Spinal Cord
Hyperbaric Oxygenation (HBO) in Traumatic Spinal Cord Injury. (EOS) - Pilot Study
Hypothesis of the Study: Based on the presented results, the investigator hypothesises that HBO preserves neurons that are not irreversibly damaged (i.e. severed) during initial trauma, thus enabling regain of their function.
- Trial name
- NCT03101982
- Testing
- HBO
- Where
- Austria
- Volunteers
- 11 people
- Sponsor
- Medical University of Graz
Sarcopenic Obesity, Spinal Cord Injuries
Sarcopenic Obesity in Neurodisabilities
To describe the frequency and thresholds for sarcopenic obesity in neurodisabled persons and the fat and lean mass distribution based on various neurodisabilities
- Conditions
- Sarcopenic Obesity, Spinal Cord Injuries, Stroke, Multiple Sclerosis
- Trial name
- SarcObeNDS (NCT03863379)
- Testing
- whole body DXA
- Where
- Greece
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Dionyssiotis, Yannis, M.D.
Spinal Cord Compression, Spinal Cord Injuries
Enhancing Recovery in Non-Traumatic Spinal Cord Injury
The investigators have spent the last decade uncovering unique metabolic and functional abnormalities in the brains of patients with spinal cord compression.
- Conditions
- Spinal Cord Compression, Spinal Cord Injuries, Cervical Spondylosis, Myelopathy Cervical
- Trial name
- NCT03320759
- Testing
- Occupational therapy rehabilitation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Western University, Canada
Spinal Cord Injuries, Acute Spinal Cord Injury
Stem Cells in Spinal Cord Injury
This is a multicenter, randomized, double-blind, placebo-controlled and delayed-start phase II/III clinical study.
- Conditions
- Spinal Cord Injuries, Acute Spinal Cord Injury, Paraplegia, Spinal, Paraplegia; Traumatic
- Trial name
- SCI2 (NCT03935724)
- Testing
- Neuro-Cells
- Where
- 2 sites in Denmark, Spain
- Volunteers
- 16 people
- Sponsor
- Neuroplast
Spinal Cord Injury Cervical
Cell Therapy for Chronic Traumatic Cervical Incomplete Spinal Cord Injury
This is a double-blind, randomized, placebo-controlled, multicenter clinical trial in which 18 patients affected with chronic traumatic incomplete cervical spinal cord injury will be randomized to either the active treatment (2…
- Trial name
- NCT05054803
- Testing
- WJ-MSC (XCEL-UMC-BETA)
- Where
- 2 sites in Spain
- Volunteers
- 18 people
- Sponsor
- Banc de Sang i Teixits
Stroke, Ischemic, Stroke Hemorrhagic
Exploring Accessible Beauty for Individuals With Upper Extremity Deficits
The purpose of this study is to investigate the accessibility of beauty products for individuals with upper extremity disabilities.
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Stroke (CVA) or TIA, Stroke, Acute
- Trial name
- NCT05945784
- Testing
- Use of Rare Beauty makeup products
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Acute Spinal Cord Injury
AC105 in Patients With Acute Traumatic Spinal Cord Injury
The principal aim of this study was to establish the feasibility of rapid administration, safety, and tolerability of AC105 in patients with acute spinal cord injury.
- Trial name
- AC105 (NCT01750684)
- Testing
- AC105
- Volunteers
- 15 people
- Sponsor
- Acorda Therapeutics
Stroke, Spinal Cord Injuries
The Roll of Balance Confidence in Gait Rehabilitation in Persons With a Lesion of the Central Nervous System
Persons with an injury of the central nervous system clearly experience motor impairments. Among the most commonly described consequences are gait abnormalities and impaired balance.
- Conditions
- Stroke, Spinal Cord Injuries, Traumatic Brain Injury
- Trial name
- NCT05503316
- Testing
- Dynamic balance training, Traditional gait rehabilitation
- Where
- Belgium
- Volunteers
- 42 people
- Sponsor
- University Hospital, Ghent
Cervical Spinal Cord Injury
Study to Assess the Efficacy and Safety of VX-210 in Subjects With Acute Traumatic Cervical Spinal Cord Injury
The purpose of this study is to determine the efficacy and safety of VX-210 in subjects with Acute Traumatic Cervical Spinal Cord Injury.
- Trial name
- NCT02669849
- Testing
- VX-210
- Where
- 39 sites in United States, Canada
- Volunteers
- 70 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Traumatic Spinal Cord Injury
Early Pharmacological Treatment of Acute Spasticity After Spinal Cord Injury
The objective of this clinical trial is to evaluate if early detection of spasticity and immediate treatment with oral baclofen during acute care prevents problematic spasticity and improves neurofunctional recovery after tSCI.
- Trial name
- NCT06564714
- Testing
- Early baclofen Intervention, Usual routine care
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Spinal Cord Trauma
Autoimmunity And Immune Deficiency After Spinal Cord Injury: Association With Rehabilitation Outcomes
The SCIentinel-prolong study systematically analyzes humoral autoantibody responses and thier interaction with post-spinal cord injury (SCI) immune-deficiency and infections as well as their association with the clinical course…
- Trial name
- NCT04211636
- Volunteers
- 81 people
- Sponsor
- Marcel Kopp, MD
Stroke, Traumatic Brain Injury
Gait Adaptation for Stroke Patients With Augmented Reality
The GASPAR trial is a pragmatic, parallel-arms, single-center, non-blinded, superiority randomized control trial in neurorehabilitation.
- Conditions
- Stroke, Traumatic Brain Injury, Spinal Cord Injury
- Trial name
- GASPAR (NCT02808078)
- Testing
- Gait training with augmented reality, Standard training
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- Philippe Terrier
Traumatic Spinal Cord Injury
The Austrian Spinal Cord Injury Study
Traumatic spinal cord injury (tSCI) is a debilitating disease that leads to neurological deficits and often has long-term effects including severe lifelong disability.
- Trial name
- ASCIS (NCT03109782)
- Where
- 18 sites in Austria
- Volunteers
- 1,000 people
- Sponsor
- Paracelsus Medical University