Clinical trials: Traumatic Wound Infection
Distress, Emotional, Stress Response Among Nursing Professionals During the COVID-19
Digital Interventions to Understand and Mitigate Stress Response
Stress, anxiety, distress, and burnout are exceptionally high among healthcare workers at the frontline of the COVID-19 pandemic.
- Conditions
- Distress, Emotional, Stress Response Among Nursing Professionals During the COVID-19, Stress Reaction; Acute
- Trial name
- NCT05923398
- Testing
- Digital Intervention Group
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
All Cause Mortality, Cardiovascular Diseases
Advice of Moderate Drinking Pattern Versus Advice on Abstention on Major Disease and Mortality
The goal of this clinical trial is to test two advices on alcohol drinking in more than 10.000 Spanish adult drinkers (men of 50 or more years and women of 55 or more years).
- Conditions
- All Cause Mortality, Cardiovascular Diseases, Invasive Cancer, Liver Cirrhosis
- Trial name
- UNATI (NCT06338215)
- Testing
- Moderate Alcohol Drinking Pattern, Abstention
- Where
- Spain
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
PTSD, PTSD Symptoms
Virtual Reality Treatment for Trauma Related to COVID-19 Infection
This clinical trial aims to develop and evaluate the effectiveness of virtual reality (VR)-based exposure therapy for trauma symptoms related to COVID-19 infection.
- Trial name
- NCT07213596
- Testing
- VR Exposure Therapy, Cognitive Behavioral Therapy (CBT), Supportive Psychotherapy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soonchunhyang University Hospital
Posttraumatic Stress Disorder
Couple HOPES and COVID-19
Posttraumatic Stress Disorder (PTSD) will be a severe problem in Canada in the wake of COVID-19, especially for Military Members, Veterans, First Responders, and Healthcare Workers (MVFH).
- Trial name
- HOPES (NCT04763681)
- Testing
- Couple HOPES Guided, Internet-Delivered, Self-Help Intervention
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- York University
Covid19, Burn Out
Burnout and Distress preventiOn With caNnabidiol in Front-line Health Care workerS deAling wIth COVID-19
The objective of this work is to monitor the level of stress and overload of a group of front-line health workers (physicians, nurses and physiotherapists) who will participate in the care of patients with COVID-19 at Hospital…
- Conditions
- Covid19, Burn Out, Post Traumatic Stress Disorder
- Trial name
- BONSAI (NCT04504877)
- Testing
- Cannabidiol
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Gut Microbiota, Spleen Injury
Microbiota is Related With Increasing Infection Rates After Splenectomy
Studies has shown an increasingly infection rate after splenectomy, and there is a potential correlation between microbiota and immune system.
- Conditions
- Gut Microbiota, Spleen Injury, Infection
- Trial name
- NCT03420599
- Testing
- splenectomy
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Covid19, Mental Health Disorder
MIND/COVID-19: Mental Health Impact and NeeDs Associated With COVID-19: a Comprehensive National Evaluation in Spain
The aim of the proposed project is to provide a comprehensive assessment of the mental health impact of the ongoing COVID-19 outbreak in Spain.
- Conditions
- Covid19, Mental Health Disorder, Mental Health Conditions
- Trial name
- NCT04556565
- Where
- 18 sites in Spain
- Volunteers
- 16,000 people, healthy volunteers welcome
- Sponsor
- Jordi Alonso
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Perinatal Depression, COVID19
Global Mental Health of Urban Mothers
Mental health disorders are common during pregnancy and the postnatal period, and can have serious adverse effects on the well-being of woman and child.
- Conditions
- Perinatal Depression, COVID19, Anxiety, PTSD
- Trial name
- MUM (NCT04363177)
- Testing
- Web-based psychosocial peer-to-peer support
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Posttraumatic Stress Disorder
Telehealth 2.0: Evaluating Effectiveness and Engagement Strategies for CPT-Text for PTSD
There is a pressing need to increase capacity to treat PTSD related to or exacerbated by the COVID-19 pandemic. Texting-based therapy holds promise to increase capacity and reduce barriers to delivering evidence-based treatments…
- Trial name
- CPT-TEXT (NCT05037175)
- Testing
- CPT-Text, Culturally Informed Trauma Treatment (CITT), Retention Incentive
- Where
- 3 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Stanford University
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Cross Sectional Hospital Based Study
Risk Perception Associated With Covid-19 Among Anesthetists
Since the outbreak of the COVID-19 pandemic, the anesthesiologists are involved in the riskiest interventions e.g. airway management, endotracheal intubation, and resuscitation.
- Trial name
- NCT04861272
- Testing
- Survey
- Where
- Saudi Arabia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- King Saud University
Covid19, Post Traumatic Stress Disorder
Post-traumatic Stress, Signs of Depression and Burnout Syndrome Among Nursing Home Staff in Occitanie During the COVID-19 Pandemic
Nursing home staff face multiple stresses during the Covid-19 pandemic including personal risk of infection, risk of transmission of the virus to residents and relatives, and risk of witnessing end-of-life scenarios under…
- Conditions
- Covid19, Post Traumatic Stress Disorder, Anxiety, Depressive Disorder
- Trial name
- PSY-COEHPAD-OC (NCT04916275)
- Testing
- Cognitive tests
- Where
- 3 sites in France
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Stress Disorders, Post-Traumatic, Stress Related Disorder
Mindfulness-SOS: Stress Reduction for Refugees
The COVID-19 pandemic crisis is associated with a wide range of stressors for the general population. For forcibly displaced persons (FDPs), the turmoil of this crisis is magnified significantly, and elevated pre-existing…
- Trial name
- NCT04761510
- Testing
- Mindfulness-SOS for Refugees
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Haifa
COVID-19, Stress Disorders, Post-Traumatic
Psychological Impact of Medical Evacuations on Families of Patients Admitted to Intensive Care Unit for Severe COVID-19
At the "Métropole Savoie" hospital, to deal with the daily influx of severe patients during the second wave of COVID-19, 23 patients had to be transferred away from their home city and far from their families as part of a medical…
- Trial name
- IPES-CoV (NCT05421182)
- Testing
- Revised Impact of Event Scale, Hospital Anxiety and Depression scale, 36-Item Short Form Survey
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Metropole Savoie
Stress, Stress Disorder
The Professional Peer Resilience Initiative
The Professional Peer Resilience Initiative (PPRI) study is an observational study aimed at understanding how symptoms of traumatic stress and resilience evolve over time in the University of Minnesota (UMN) healthcare workforce…
- Conditions
- Stress, Stress Disorder, Stress, Psychological, Trauma, Psychological
- Trial name
- PPRI (NCT04396600)
- Testing
- MinnRAP Peer Support Program
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Traumatic Brain Injury, Fatigue
Brain and Gut Plasticity in Mild TBI or Post-acute COVID Syndrome Following Growth Hormone Therapy
Patients with a history of mild traumatic brain injury (mTBI) or post acute sequelae of SARS-CoV-2 (PASC) and abnormal growth hormone secretion, as measured by glucagon stimulation test, will be treated with replacement growth…
- Conditions
- Traumatic Brain Injury, Fatigue, Cognitive Impairment, COVID-19
- Trial name
- NCT03554265
- Testing
- Somatropin
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Mental Health, PTSD
Further Development and Initial Testing of RESTORE in Frontline Workers
There is considerable need for psychological intervention targeting stressor-related mental health symptoms related to COVID-19.
- Conditions
- Mental Health, PTSD, Anxiety, Depressive Symptoms
- Trial name
- RESTORE (NCT04873622)
- Testing
- RESTORE: Recovering from Extreme Stressors Through Online Resources and E-health
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Trauma, Sepsis
Prediction Study of Complications After Severe Trauma
The purpose of this study is to evaluate a clinically and economically most effective diagnostic algorithm for prediction of post-traumatic complications in a multicenter sample of severe trauma patients.
- Conditions
- Trauma, Sepsis, Multiple Organ Dysfunction Syndrome
- Trial name
- PSCAT (NCT01713205)
- Where
- 6 sites in China
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Jiang Jianxin
ART, Hiv
Strengthening Families Living With HIV in Kenya
This study seeks to use a group-based microfinance/internal lending model to develop social capital among people with HIV in Kenya.
- Conditions
- ART, Hiv, Trust, Depression, Anxiety
- Trial name
- NCT04588883
- Testing
- Kuja Pamoja - HIV
- Where
- Kenya
- Volunteers
- 843 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston