Clinical trials: Traumatic Wound Infection
PTSD, Sexual Abuse
PTSD and Risk Behavior in HIV Positive Female Adolescents
This is a qualitative study using a purposive sampling methodology to interview HIV-positive female adolescents who have experienced physical and/or sexual abuse.
- Conditions
- PTSD, Sexual Abuse, HIV Infections
- Trial name
- NCT00271882
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
Neurologic Disorder, Stroke
Home Based Tele-exercise for People With Chronic Neurological Impairments
To assess the impact of a 12-week virtual seated physical intervention on cardiovascular health and wellness in people with chronic neurological impairments (CNI).
- Conditions
- Neurologic Disorder, Stroke, Spinal Cord Injuries, Cerebral Palsy
- Trial name
- Telex (NCT04564495)
- Testing
- Seated exercise
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Burke Medical Research Institute
Infection
Regional and Seasonal Variations in the Incidence and Causative Organisms for Post-traumatic Wound Infections and Osteomyelitis After Open Fractures
To determine if there is a relationship between people with open fractures and the season and location of where the injury occurred and the infections they develop
- Trial name
- NCT03064009
- Testing
- Infection
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Washington
Covid19, Post Traumatic Stress Disorder
STRESS From in Charge Relative Facing the Announcement of Decisions Limiting or Stopping Treatments in Emergency Room During the COVID-19 Epidemic
In the context of the COVID-19 pandemic, the emergency reception services had to be radically reorganized. In this tense environment, professionals must face ethical dilemmas, make referral decisions and prioritize patients.
- Conditions
- Covid19, Post Traumatic Stress Disorder, Anxiety
- Trial name
- COVER ACC (NCT04785807)
- Testing
- Post traumatic, Anxiety and depression evaluation
- Where
- 3 sites in France
- Volunteers
- 140 people
- Sponsor
- Hospices Civils de Lyon
Anxiety Disorders, Post Traumatic Stress Disorder
Psychological Impact of Admission With Covid-19 During the SARS-CoV-2 Pandemic: Naturalistic Cohort Study With a Digital Intervention
Studies have shown that admission to hospital during a coronavirus epidemic is associated with increased levels of anxiety, depression and panic disorder.
- Conditions
- Anxiety Disorders, Post Traumatic Stress Disorder, Depressive Disorder, Covid19
- Trial name
- FeelGood (NCT04449627)
- Testing
- Feeling Good Digital App
- Volunteers
- 125 people
- Sponsor
- Royal Free Hospital NHS Foundation Trust
COVID-19 Post-Intensive Care Syndrome
Impact of Mental Health and Cognitive Disorders on Quality of Life in Severe Covid-19 Survivors
The objective of this single-center retrospective observational study is to describe cognitive and psychological outcomes and their impact on quality of life after at least 3 months of intensive care unit (ICU) discharge in…
- Trial name
- NCT05839327
- Testing
- Montreal cognitive assessment scale (MOCA)
- Volunteers
- 65 people
- Sponsor
- Hospital Sao Domingos
Anxiety, Depression
CO-PARENT: COVID-19 - Parent Action in Response to Emotions and Needs for Treatment
The purpose of this research study is to collect information to better understand caregiver responses to COVID-19 stress and to help caregivers cope with these stressors.
- Conditions
- Anxiety, Depression, Traumatic Stress Disorder
- Trial name
- Co-PARENT (NCT04431856)
- Testing
- Unified Protocol for COVID-19 Parenting Stress (UP-COVID), SHG
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Miami
Covid19, Burnout, Professional
Mental Health of Professionals Working in Pediatric Intensive Care Units During the COVID-19 Pandemic
Health professionals are extremely exposed to psychosocial risks, as they experience, in general, high levels of stress, anxiety, fatigue and suffering, due to the nature and location of their work.
- Conditions
- Covid19, Burnout, Professional, Stress Disorders, Post-Traumatic, Anxiety
- Trial name
- NCT04846907
- Testing
- Web-based survey
- Where
- Brazil
- Volunteers
- 1,148 people, healthy volunteers welcome
- Sponsor
- D'Or Institute for Research and Education
Urinary Tract Infection, Head Injury
Video Discharge Instructions (VDI) as Adjuncts to Written Discharge Instructions in the Emergency Department
Patients seen in the ED with either a laceration, minor head injury, or urinary tract infection will be randomized to one of two groups.
- Conditions
- Urinary Tract Infection, Head Injury, Laceration
- Trial name
- NCT02882256
- Testing
- Video discharge instructions
- Where
- United States
- Volunteers
- 193 people
- Sponsor
- George Washington University
Covid19, Delirium
Neurotropism and Neuroinflammation in COVID-19 Patients With Delirium.
Emerging evidence indicates that SARS-CoV-2, the etiologic agent of COVID-19, can cause neurological, neuropsychological and psychiatric complications.
- Conditions
- Covid19, Delirium, Post-traumatic Stress Disorder
- Trial name
- BRAINSTORM (NCT04785157)
- Testing
- serology testing profiles description, immune response characterization, in vivo brain PET-TSPO acquisitions
- Where
- 2 sites in France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Toulouse
Residual Limb Pain, Stump Pain
Post-Amputation Stump Infection as a Predictor of Persistent Residual Limb Pain: A Prospective Cohort Study
Persistent residual limb pain is common after traumatic amputation and significantly impairs rehabilitation and prosthetic use. Postoperative stump infection may contribute to peripheral nerve sensitization, scar fibrosis, and…
- Conditions
- Residual Limb Pain, Stump Pain, Post-Amputation Pain, Surgical Site Infection
- Trial name
- INF-STUMP-PAIN (NCT07438795)
- Volunteers
- 150 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Neurologic Manifestations, Psychiatric Disorders
Cohort of Patients With Covid-19 Presenting Neurological or Psychiatric Disorders (CoCo-Neurosciences)
Covid-19 pandemic now affects more than two million people worldwide. The neurotropism of the virus is assumed by its frequent association with neurological symptoms (anosmia, ageusia, headaches) but the extent of the central or…
- Conditions
- Neurologic Manifestations, Psychiatric Disorders, COVID-19
- Trial name
- CoCo-Neuro (NCT04362930)
- Where
- France
- Volunteers
- 730 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fractures, Bone, Infections
Clinical Metagenomic of Post-traumatic Infections
Treatment of fracture related infection is challenging and often lead to failure in such situation that carry a high health cost burden.
- Trial name
- METADIAG (NCT05770856)
- Testing
- Metagenomic sequencing
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
PTSD
Glecaprevir/Pibrentasvir for the Treatment of PTSD
An open-label pilot study to further investigate glecaprevir/pibrentasvir (GLE/PIB), a direct acting antiviral (DAA) that has been associated with posttraumatic stress disorder (PTSD) symptom improvement when prescribed for the…
- Trial name
- NCT05446857
- Testing
- Glecaprevir / Pibrentasvir Pill
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- White River Junction Veterans Affairs Medical Center
Wound Closure, Brain Tumor Adult
Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures
This research is studying a device already approved by the Food and Drug Administration (FDA) to treat wound closures. Researchers are studying a large group of people to continue to learn information about the safety of the…
- Conditions
- Wound Closure, Brain Tumor Adult, Spine, Neurovascular
- Trial name
- NCT07225101
- Testing
- STRATAFIX PDS and Monocryl suture
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of Michigan
Traumatic Brain Injury, Ventilator Associated Pneumonia
Effect of E-BAL on Severity of VAP Assessed Through CPIS on the Patients of Traumatic Brain Injury in Neurocritical Care, Also Effect on Days of Ventilation and ICU Stay.
Severe traumatic brain injury (STBI) is a leading cause of disability, mortality, and economic burden worldwide. The impact of severe traumatic brain injury (STBI) on the economy of developing countries like Pakistan is…
- Trial name
- NCT04977843
- Testing
- EARLY BRONCHOALVEOLAR LAVAGE
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Jinnah Hospital
Covid-19, Mental Health Disorder
The Covid-19 HEalth caRe wOrkErS (HEROES) Study
Since December 2019 the world has been shaken with an enormous global threat: the Covid-19 pandemic. This new kind of coronavirus is generating an unprecedented impact both on the general population and on the healthcare systems…
- Conditions
- Covid-19, Mental Health Disorder, Stress Disorder, Anxiety
- Trial name
- HEROES (NCT04352634)
- Testing
- Exposure to the SARS-CoV-2 and its consequences
- Where
- 22 sites in United States, Argentina and 19 more
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Chile
HIV Infection
Long-Term Survival With HIV: Psychological and Behavioral Factors Associated With the Transition From Adolescence to Young Adulthood
This study will examine the emotional and behavioral aspects of long-term survival of HIV/AIDS among adolescents and young adults with HIV infection.
- Trial name
- NCT00026806
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- National Cancer Institute (NCI)
Mental Health Wellness 1, PTSD
Mental Health Outcomes in Healthcare Workers During COVID-19
An online survey will be sent to healthcare workers (HCWs) in acute care hospitals to explore a variety of risk factors for negative psychological outcomes and levels of anxiety, depression and post-traumatic stress symptoms…
- Conditions
- Mental Health Wellness 1, PTSD, Anxiety, Stress
- Trial name
- NCT04397848
- Where
- Canada
- Volunteers
- 3,852 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Alcohol Use Disorder, Depression
Zambia Common Elements Treatment Approach Pilot Study
This is a randomized controlled trial (RCT) evaluating the effectiveness of an alcohol brief intervention alone compared to the brief intervention plus an evidence-based psychotherapy (CETA) in reducing alcohol misuse and…
- Conditions
- Alcohol Use Disorder, Depression, Post-traumatic Stress Disorder, HIV/AIDS
- Trial name
- ZCAP (NCT03966885)
- Testing
- Brief Intervention, Common Elements Treatment Approach (CETA)
- Where
- Zambia
- Volunteers
- 160 people
- Sponsor
- Columbia University