Clinical trials: Traumatic Wounds
Traumatic Brain Injury, Suicidality
Executive Dysfunction and Suicide in Psychiatric Outpatients and Inpatients
Those with traumatic brain injury (TBI) are at increased risk for suicidal behavior, and suicidality is associated with executive dysfunction.
- Trial name
- NCT01043432
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Amputation, Amputation, Traumatic
GaMA Metric to Quantify Functional Importance of Various Upper Limb Prosthetic Devices
The goal of this study is to utilize the Gaze and Movement Assessment (GaMA) metric to assess the effect of different prosthetic components on compensatory movements used to complete activities of daily living.
- Conditions
- Amputation, Amputation, Traumatic, Amputation; Traumatic, Hand, Amputation; Traumatic, Limb
- Trial name
- NCT06420687
- Testing
- Clinically prescribed prosthesis, Experimental prosthesis - Wrist rotation + 1-DOF, Experimental prosthesis - Wrist rotation + Wrist flexion +1-DOF
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Breast Cancer, Traumatic Brain Injury
Purpose in Life Survey
At present, there is no empirical data that specifies the likely prevalence of purpose in life disruption among various clinical populations.
- Trial name
- PIL (NCT05790278)
- Testing
- Survey
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mary Radomski
Traumatic and/or Non-traumatic Brain Injury
Assessing Special Features of Impaired Gait After Acquired Brain Injury With an Instrumented Treadmill
Hemiparetic gait following acquired brain injury (ABI) is grossly characterized by decreased speed of walking, increased stance time on the unaffected side, and decreased stance time on the affected side.These abnormalities are…
- Trial name
- NCT01413321
- Where
- Israel
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Concussion, Mild
The Combined Effect of Chronic Cannabis Use and Subconcussive Head Impacts on Brain Health
The purpose of this pilot study is to better understand the effects of chronic cannabis (THC) use on the neural responses to subconcussive head impacts, as a form of repetitive soccer headings.
- Trial name
- NCT04641832
- Testing
- Soccer heading
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Indiana University
Focus: Healthy Adults Without Brain Injury
Normative Datasets for Assessments Planned for Mild Traumatic Brain Injury (NORMAL)
The purpose of the research study is to collect information about brain function and structure among active duty military personnel or civilians who are healthy.
- Trial name
- NORMAL (NCT01925963)
- Where
- 2 sites in United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Lindell Weaver
Traumatic Brain Injury
The Research for New Clinical Diagnostic Strategy of Specific Biomarkers for Traumatic Brain Injury
Traumatic brain injury (TBI) is the most common type of nerve injury and it severely endangers the public health. It is necessary to accurately measure the early neurological function of brain injury for monitoring its prognosis…
- Trial name
- NCT03976492
- Testing
- diagnostic of specific biomarkers
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Baiyun Liu
Acquired Brain Injury, Subarachnoid Hemorrhage
Cohort Study on the Effects of Aging in Acquired Brain Injury Patients
A prospective cohort study (questionnaires), with an embedded case control study (neuropsychological assessments) in which the data is gathered within a timeframe of 3 years.
- Conditions
- Acquired Brain Injury, Subarachnoid Hemorrhage, Traumatic Brain Injury, Cerebrovascular Accident
- Trial name
- BRAINReADAPT (NCT05499806)
- Where
- 2 sites in Netherlands
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Traumatic Brain Injury
Evaluation of Consciousness Impairment in Severe TBI and Full-cycle Neuroregulation Based on Multimodal Imaging
The goal of this observational study is to learn about in Evaluation of consciousness impairment in severe TBI and full-cycle neuroregulation based on multimodal imaging.
- Trial name
- NCT06469827
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Traumatic Brain Injury
Transforming Research and Clinical Knowledge in Geriatric Traumatic Brain Injury (TRACK-GERI)
The purpose of this study is to improve the diagnosis and prediction of recovery after traumatic brain injury (TBI) in adults age 65 years and older.
- Trial name
- TRACK-GERI (NCT07296783)
- Where
- 3 sites in United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Traumatic Brain Injury
Imaging of Traumatic Brain Injury Metabolism Using Hyperpolarized Carbon-13 Pyruvate
This project is to evaluate sensitivity and specificity of hyperpolarized 13C-pyruvate as imaging agents of altered cerebral glycolysis and mitochondrial dysfunction and assess pyruvate utilization in mitochondria in Traumatic…
- Trial name
- HPTBI (NCT03502967)
- Testing
- Hyperpolarized [1-13C] Pyruvate, Hyperpolarized [2-13C] Pyruvate
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Traumatic Shock, Hemorrhagic Shock
Prehospital Norepinephrine and Early Mortality in Traumatic Shock
The effect of early, prehospital norepinephrine use in patients with traumatic shock on mortality is unknown. Recent existing observational evidence from single system data (US, France, Japan) are conflicting.
- Conditions
- Traumatic Shock, Hemorrhagic Shock, Traumatic Brain Injury, Hypotension and Shock
- Trial name
- NCT04497155
- Testing
- Norepinephrine
- Volunteers
- 2,164 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Traumatic Brain Injury (TBI) Patients, Severe Traumatic Brain Injury
SeeMe: Using Automated Facial Tracking to Detect Voluntary Behavior in Brain Injury
Objective: This prospective interventional study introduces "SeeMe," an automated, high-resolution computer vision platform designed to objectively quantify microscopic, auditory command-evoked movements in patients with…
- Trial name
- NCT07560631
- Testing
- SeeMe Multimodal Auditory Command Protocol
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Traumatic Brain Injury, Stroke
Remote Neuropsychological Assessment of Patients With Neurological Disorders and Injuries
For the last decades, many aspects of human life have been altered by digital technology. For health care, this have opened a possibility for patients who have difficulties travelling a long distance to a hospital to meet with…
- Conditions
- Traumatic Brain Injury, Stroke, Multiple Sclerosis, Parkinson Disease
- Trial name
- NCT05819008
- Testing
- Neuropsychological Assessment
- Where
- Sweden
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Umeå University
All Cause Mortality, Cardiovascular Diseases
Advice of Moderate Drinking Pattern Versus Advice on Abstention on Major Disease and Mortality
The goal of this clinical trial is to test two advices on alcohol drinking in more than 10.000 Spanish adult drinkers (men of 50 or more years and women of 55 or more years).
- Conditions
- All Cause Mortality, Cardiovascular Diseases, Invasive Cancer, Liver Cirrhosis
- Trial name
- UNATI (NCT06338215)
- Testing
- Moderate Alcohol Drinking Pattern, Abstention
- Where
- Spain
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Cognition Disorder, Functional Brain Imaging
fMRI and NIRS Imaging for Traumatic Brain Injury
Background: The amount of blood flowing in brain areas goes up when those areas are being used for activities, such as movement or seeing.
- Trial name
- NCT01668758
- Volunteers
- healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Concussion Post Syndrome, Headaches Posttraumatic
Pediatric Concussion Outcomes
This is a randomized, placebo-controlled, double-blinded trial in which subjects with a post concussive headache meeting inclusion criterion will be assigned to one of two treatment groups: placebo or nortriptyline.
- Conditions
- Concussion Post Syndrome, Headaches Posttraumatic, Mild Traumatic Brain Injury
- Trial name
- PeCon (NCT04226365)
- Testing
- Nortriptyline
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Lancaster General Hospital
MTBI - Mild Traumatic Brain Injury
Imaging of Injury Mechanism and Interaction of Intestinal Bacteria in Children With Mild Traumatic Brain Injury
Traumatic brain injury (TBI) is the leading cause of disability in children and young adults. Children with moderate to severe TBI are typically at risk of poor functional outcome in terms of neurocognitive impairment and…
- Trial name
- NCT05090007
- Testing
- magnetic resonance image, gut microbiota
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Cervicogenic Headache, Neck Pain
Multi Cervical Unit Measures of Cervical Isometric Strength and Range of Motion: A Pilot Study
This study is designed to collect normative data on cervical isometric strength and range of motion to supplement an existing normative data base.
- Conditions
- Cervicogenic Headache, Neck Pain, Whiplash, Kyphotic and Reversed Cervical Curves
- Trial name
- NCT00510757
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Logan College of Chiropractic
Aquired Brain Injury, Traumatic Brain Injuries
Effectiveness of a Customized Digital Platform to Increase Coordination of Care and Uptake of Evidence-based Practices
Background: Cardiovascular and neurological conditions are major causes of disability worldwide. Early, intensive rehabilitation is essential but often challenging to access in current healthcare systems.
- Conditions
- Aquired Brain Injury, Traumatic Brain Injuries, Stroke, Cardiovascular Diseases
- Trial name
- NCT06867081
- Testing
- The intervention will be the BRILLIANT Platform, an online platform which provides five Modules aimed at increasing coordination of care and direct rehabilitation time
- Where
- 2 sites in Canada
- Volunteers
- 962 people, healthy volunteers welcome
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal