Clinical trials: Treated Hypertension
Hypercholesterolemia, Hypertension
Evaluating "Health at Every Size"(HAES) as an Alternative Obesity Treatment Model
Increasingly more individuals are trying to lose weight. Indeed, many women, regardless of their size, experience a life-long battle and preoccupation with their weight.
- Conditions
- Hypercholesterolemia, Hypertension, Depression, Diabetes Mellitus, Type 2
- Trial name
- NCT00074633
- Testing
- Health at Every Size (HAES), Diet (Traditional, moderate energy restriction)
- Where
- 2 sites in United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Hypertension, Aging
Nicotinamide Riboside for Treating Elevated Systolic Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults
Aging is the primary risk factor for cardiovascular diseases (CVD), the number one cause of death in developed societies. Systolic blood pressure (SBP) increase with age and is a key intermediary factor linking aging to increased…
- Trial name
- NCT03821623
- Testing
- Nicotinamide riboside
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Douglas Seals
Hypertension, Hyperlipidemia (E.G., Hypercholesterolemia)
A Study to Evaluate the Pharmacokinetic Interaction and Safety Between BR1018-1 and BR1018-2 in Healthy Adult Subjects
The purpose of this study is to evaluate the pharmacokinetic characteristics and compare the safety and tolerability after repeated separate or combined administrations of BR1018-1 and BR1018-2 in healthy adults.
- Trial name
- NCT05460364
- Testing
- BR1018-1, BR1018-2
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Chronic Disease, Obesity
Active and Healthy Brotherhood: A Program for Chronic Disease Self-Management for Black Men
This study will test ways to improve health behaviors using an intervention that has been specially designed for African-American men.
- Conditions
- Chronic Disease, Obesity, Hypertension, Diabetes
- Trial name
- NCT02362737
- Testing
- Active and Healthy Brotherhood (AHB)
- Where
- United States
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- Gramercy Research Group
Hypertension
The Multicenter Randomized HYpertension and VALUEs (HYVALUE) Trial
The objective of this study is to reduce the effects of stereotype threat on the adherence of African American patients with hypertension.
- Trial name
- HYVALUE (NCT03028597)
- Testing
- Intervention Values Affirmation, Control Values Affirmation
- Where
- 3 sites in United States
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Prehypertension, Gout
Study of Febuxostat Effect on Blood Pressure in Patients With High Normal Blood Pressure
High normal blood pressure, also called prehypertension, is a significant problem. High uric acid in the blood, the same thing that causes gout, may cause higher blood pressures.
- Conditions
- Prehypertension, Gout, Pulse Wave Velocity, Hypertension
- Trial name
- NCT01472692
- Testing
- Febuxostat
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Hypertension
Crossover Bioequivalence Study of Irbesartan 300 mg Tablets Under Fed Conditions
The objective of this study was to prove the bioequivalence of Roxane Laboratories' Irbesartan 300 mg Tablets under fed conditions.
- Trial name
- NCT01712100
- Testing
- Irbesartan, Avapro
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Hypertension, Chronic Stable Angina
Bioequivalency Study of Amlodipine Tablets Under Fasting Conditions
The objective of this study was the bioequivalence of a Roxane Laboratories' Amlodipine Besylate tablets, 10 mg, to Norvasc® Tablets, 10 mg (Pfizer) under fasting conditions using a single-dose, randomized, 2-treatment, 2-period…
- Conditions
- Hypertension, Chronic Stable Angina, Vasospastic Angina
- Trial name
- NCT00602017
- Testing
- Amlodipine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Systemic Sclerosis, Pulmonary Arterial Hypertension
Extracellular Vesicle Dynamics Predicting Vascular Complications and Treatment Response in Systemic Sclerosis
Systemic sclerosis is a multisystem autoimmune disease characterized by vascular dysfunction, immune dysregulation, and progressive tissue fibrosis.
- Conditions
- Systemic Sclerosis, Pulmonary Arterial Hypertension, Digital Ulcers, Vascular Complications
- Trial name
- EVOLVE-SSc (NCT07717060)
- Testing
- Blood sampling, nailfold capillaroscopy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Preventative Medicine
Using a Telehealth and Shared Decision-Making Model to Address Preventative Medicine Strategies Among Communities in Louisiana
This study is a 12-18 month behavioral intervention study to assess the impact of enrolling individuals a clinical pharmacist run Telehealth education focused on wellness and preventive health strategies.
- Trial name
- NCT05676970
- Testing
- Telehealth: Personalized Preventative Medicine Strategies, TeleHealth: Preventative Medicine Education
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Xavier University of Louisiana.
Preeclampsia
Combined Multi-marker Screening and Treatment With Aspirin for Pre-eclampsia Prevention
Phase III two arm double-blinded randomised controlled trial to examine the effect of prophylactic low-dose aspirin from the first-trimester of pregnancy in women at increased risk for PET on the incidence and severity of the…
- Trial name
- ASPRE (NCT02301780)
- Testing
- Aspirin
- Where
- Israel
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Hypertension
An Comparative Pharmacokinetic Study of Amlodipine Besylate Controlled-release Tablets,China in Normal, Healthy, Adult, Human Subjects Under Fasting Conditions
Amlodipine Besylate Controlled-release Tablets in Healthy Volunteers in a Randomized, Open, Two-cycle, Double-cross, Fasting State Comparative Pharmacokinetic Study.
- Trial name
- NCT05667818
- Testing
- Amlodipine besylate tablets (trade name: Norfloxacin ®）, Amlodipine besylate controlled-release tablets
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Overseas Pharmaceuticals, Ltd.
Hyperlipidemia, Diabetes
Point-of-Care Testing (POCT) Detection and Management of Metabolic Syndrome in Patients With Mental Illness
The study was a 12-month, multi-centered, quasi-experimental design to assess point-of-care (POCT) screening/monitoring of subjects on antipsychotic agents for metabolic syndrome.
- Conditions
- Hyperlipidemia, Diabetes, Hypertension
- Trial name
- NCT02029989
- Testing
- Glucose and lipids, Glycosylated Hemoglobin A1c, Blood Pressure and Heart Rate
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Optic Disc Swelling
Antiacne Medications Pseudotumor Cerebri
The exact incidence of optic disc swelling and idiopathic intracranial hypertension in patients using antiacne medication is not known so far.
- Trial name
- AAMPTC (NCT02149615)
- Testing
- Retinal nerve fibre layer measurement
- Where
- Switzerland
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hypertension, Potassium Imbalance
Occurrence of Dyskalemia With Treatment for Hypertension
Hypertension is a major public health issue associated with significant morbidities and mortality. Fixed-dose combination (FDC) pills, combining 2 or more classes of antihypertensive medications have considerable appeal because…
- Trial name
- OK (NCT05155436)
- Testing
- Fixed Dose Combination pill of Telmisartan 40mg and Amlodipine 5 mg
- Where
- Bangladesh
- Volunteers
- 1,090 people, healthy volunteers welcome
- Sponsor
- National Heart Foundation of Bangladesh
Hypertension
Effectiveness of a Valsartan Based Versus an Amlodipine Based Treatment Strategy in naïve Patients With Stage 1 or Stage 2 Hypertension or in Patients Uncontrolled on Current Monotherapy
The population for this current study will include stage 1 and stage 2 hypertensive patients who are newly diagnosed or didn't have treatment during the last 3 months and patients who are currently treated but uncontrolled on…
- Trial name
- NCT00304226
- Testing
- valsartan, amlodipine
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 1,288 people, healthy volunteers welcome
- Sponsor
- Novartis
Pre-Eclampsia
Impact of Antichlamydial Treatment on the Rate of Preeclampsia
This randomized, double blinded controlled trial included 1200 healthy primigravidae who attended an outpatient clinic at 16-20weeks of pregnancy.
- Trial name
- NCT03233880
- Testing
- Azithromycin 1gm
- Where
- Egypt
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Healthy Volunteers, Pulmonary Arterial Hypertension
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
A study to learn about the treatment LTP001 in healthy participants (Part A) and in participants with PAH (Part B)
- Trial name
- NCT06649110
- Testing
- LTP
- Where
- 87 sites in United States, Argentina and 16 more
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Systemic Arterial Hypertension, Pharmacotherapy
Use of Technology to Optimize Hypertension Treatment in Elderly People in Primary Care
The control of blood pressure (BP) in the elderly is influenced by several factors, among them, the measurement methodology. The measurement of BP in the office is prone to failures, so the use of technology associated with blood…
- Conditions
- Systemic Arterial Hypertension, Pharmacotherapy, Pharmaceutical Care
- Trial name
- MINOR (NCT04861727)
- Testing
- MRPA procedure, Pharmaceutical intervention
- Where
- Brazil
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Federal University of Bahia
HIV, Tuberculosis
Evaluation of South Africa's National Adherence Strategy
NOTE THAT THE STUDY IS LED BY SOUTH AFRICA NATIONAL DEPARTMENT OF HEALTH AND WORLD BANK WITH SUPPORT FROM BOSTON UNIVERSITY. The South Africa National Department of Health (NDOH) intends to launch its newly developed National…
- Conditions
- HIV, Tuberculosis, Diabetes, Hypertension
- Trial name
- ENHANCE (NCT02536768)
- Testing
- Minimum package of interventions to improve ART adherence
- Where
- South Africa
- Volunteers
- 8,020 people, healthy volunteers welcome
- Sponsor
- Boston University