Clinical trials: Treatment
Diabetes Mellitus Type 2, Non-alcoholic Fatty Liver Disease
Efficacy of Amlexanox vs. Placebo in Type 2 Diabetic Patients
This study involves research about an investigational medicine called Amlexanox. The reason for this study is to find out how Amlexanox can improve type 2 diabetes, insulin resistance, obesity and non-alcoholic fatty liver…
- Conditions
- Diabetes Mellitus Type 2, Non-alcoholic Fatty Liver Disease, Obesity
- Trial name
- NCT01975935
- Testing
- Amlexanox
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Michigan
Major Depressive Disorder
Changes in Cerebral Glucose Metabolism After Electroconvulsive Therapy (ECT)
There exist already a few studies that have measured changes of brain metabolism pre and post Electroconvulsive Therapy (ECT) by Positron emission tomography (PET) but these were all performed in a small number of patients and…
- Trial name
- NCT01514435
- Testing
- Electroconvulsive therapy, 18-Fluoro-desoxy-glucose positron emission tomography
- Where
- Austria
- Volunteers
- 13 people
- Sponsor
- Medical University of Graz
Breast Cancer
Letrozole Plus Oral Cyclophosphamide Plus/Minus Sorafenib as Primary Systemic Treatment in Breast Cancer Patients
Endocrine therapy is the mainstay of systemic treatment in patients with endocrine responsive breast cancer. Aromatase inhibitors are the most active agents in post-menopausal women.
- Trial name
- NCT00954135
- Testing
- letrozolo+cyclophosphamide, letrozolo+sorafenib+cyclophosphamide
- Where
- 2 sites in Italy
- Volunteers
- 190 people
- Sponsor
- University of Turin, Italy
Colorectal Cancer
Korean Red Ginseng in Treating Patients With Fatigue Caused by Chemotherapy for Colorectal Cancer
Korean Red Ginseng may improve fatigue in healthy subject. It is not yet known whether Korean Red Ginseng is effective compared with a placebo in chemotherapy.
- Trial name
- KRG (NCT02039635)
- Testing
- Korean Red Ginseng
- Where
- South Korea
- Volunteers
- 438 people
- Sponsor
- Korea Ginseng Corporation
Amblyopia
Assessment of Device for Treatment of Amblyopia
The study will evaluate the effect of Reviview™, a dichoptic video display device for administrating a novel treatment protocol for Amblyopia (lazy eye) in kids.
- Trial name
- NCT02003235
- Testing
- Daily watching videos using Reviview™, a dichoptic video display device, for 60 min
- Where
- Israel
- Volunteers
- 35 people
- Sponsor
- Visior Technologies Ltd.
Sintilimab and Anlotinib in Combination With Chemotherapy
Sintilimab and Anlotinib Combined With Chemotherapy in Neoadjuvant Treatment of Resectable Esophageal Cancer
The study focused on patients with T2-4NxM0 resectable esophageal carcinoma. Neoadjuvant treatment involved administering anlotinib (10 mg orally, once a day, 2 weeks on and 1 week off) for anti-angiogenesis and sintilimab (200…
- Trial name
- NCT06015035
- Testing
- Sintilimab and anlotinib in combination with chemotherapy
- Where
- 2 sites in China
- Volunteers
- 17 people
- Sponsor
- Tang-Du Hospital
Immune Effector Cell Associated Hematotoxicity
Safety and Efficacy of Umbilical Cord Blood-Derived Mesenchymal Stem Cells in the Treatment of Long-Term Cytopenia After CAR-T Therapy
This study is a single arm, open label, exploratory clinical study aimed at evaluating the efficacy, and safety of allogeneic umbilical cord blood-derived mesenchymal stem cells in the treatment of long-term cytopenia after CAR-T…
- Trial name
- MSC-ICAHT (NCT07212335)
- Testing
- Mesenchymal Stem Cell Infusion
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Ischemic Heart Disease, Prostate Adenocarcinoma
Ischemic Heart Disease in Male With Prostate Adenocarcinoma
The purpose of the study: to increase the efficiency of diagnosis, treatment and prediction of the course of coronary heart disease in patients with adenocarcinoma of the prostate gland, depending on the hormonal status by…
- Trial name
- NCT03474835
- Testing
- ISCHEMIC HEART DISEASE diagnostic
- Where
- Ukraine
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dnipropetrovsk State Medical Academy
Haemophilia
Effectiveness of the uPatient Platform in Prophylactic Treatment in Hemophilia
Research project whose main objective is to evaluate the use of a technology platform (uPatient) to register the prophylactic treatment of patients with hemophilia treated in different Hematology and Hemotherapy services of…
- Trial name
- uPatient (NCT02581735)
- Testing
- Patients with haemophilia
- Volunteers
- 40 people
- Sponsor
- Real Fundación Victoria Eugenia
Meniere's Disease
Famvir for Treatment of Hearing in Unilateral Meniere's Disease
The specific aim of this study is to determine the efficacy of treatment with famciclovir in unilateral Meniere's Disease patients, specifically whether hearing can be improved.
- Trial name
- Famvir (NCT01526408)
- Testing
- Famciclovir
- Volunteers
- 11 people
- Sponsor
- House Research Institute
Hypersensitivity Pneumonitis
"Randomized Controlled Trial Testing the Efficacy of Corticosteroid Therapy Versus Placebo in Fibrotic Hypersensitivity Pneumonitis"
Hypersensitivity Pneumonitis (HP) is an immune-mediated disease that manifests as interstitial lung disease after exposure to an inhaled antigen, often unidentified. HP can be classified as non-fibrotic or fibrotic HP.
- Trial name
- RUBY (NCT07210008)
- Testing
- Prednisolone
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Wounds and Injuries, Sports Physical Therapy
Previous Injury History and Performance of Male Elite Ice Hockey Players
BACKGROUND: In ice hockey, skating is a combination of speed, power, and balance. OBJECTIVE:The aim of this study is to examine the relationship between previous injury history and on-ice and off-ice performance of elite male ice…
- Trial name
- NCT04415125
- Testing
- Applying on-ice and off-ice performance tests
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Baskent University
Congenital Cataract
Capsulorhexis Size and Capsular Outcome
Different capsulorhexis size results in different capsular outcome when treating pediatric cataract, and there should be an appropriate capsulorhexis size for the best capsular outcome.
- Trial name
- NCT02158325
- Testing
- anterior capsulorhexis sizes
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Sun Yat-sen University
Tumor Pancreas
Evaluate the Safety and Efficacy of BGT007H Cell Therapy in Patients With Relapsed/Refractory Pancreatic Cancer
The primary objective of this study is to evaluate the safety and tolerability of BGT007H cell therapy in patients with recurrent/refractory pancreatic cancer.
- Trial name
- NCT06478225
- Testing
- BGT007H Cell Injection
- Where
- China
- Volunteers
- 12 people
- Sponsor
- RenJi Hospital
Parkinson's Disease, Depression
Magnetic Stimulation for Parkinson Disease
During transcranial magnetic stimulation (TMS), a magnetic coil is placed on the front part of the head. Electric current passes through the coil in brief pulses.
- Trial name
- NCT00029276
- Testing
- Prefrontal transcranial magnetic brain stimulation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Major Depressive Disorder
VR-Moodboost; an Innovative Virtual Reality Treatment for Adolescents With Depression
Major depressive disorder (MDD) is a prevalent and disabling mental health condition. A recent meta-analysis shows that across all forms of psychotherapy, only 43% of all depressive patients fully recover from MDD and relapse…
- Trial name
- VR-Moodboost (NCT05486676)
- Testing
- VR-Moodboost; a Virtual Reality intervention for depression to enhance positive affect and reduce depressive symptoms.
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Claudi Bockting
Chronic Graft-versus-host Disease
MSC for Treatment of cGVHD After Allo-HSCT
The purpose of this study is to evaluate the efficacy of mesenchymal stem cells in patients with chronic graft-versus-host disease.
- Trial name
- NCT04692376
- Testing
- Mesenchymal stem cells, Glucocorticoids, cyclosporine
- Where
- China
- Volunteers
- 152 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Major Depressive Disorder
Comparison of Tianeptine Versus Escitalopram Patients Major Depressive Disorder
The primary object of this study is to confirm the superiority of tianeptine compared to escitalopram on effects that improves subjective and objective cognitive impairments in patients suffering from major depressive disorder.
- Trial name
- CAMPION (NCT01309776)
- Testing
- Tianeptine, Escitalopram
- Where
- 6 sites in South Korea
- Volunteers
- 164 people
- Sponsor
- Samsung Medical Center
Intrauterine Insemination
GnRH Agonist and Intrauterine Insemination
The aim of this study is to assess whether GnRH agonist administration in the luteal phase improves pregnancy outcome in intrauterine insemination (IUI) cycles.
- Trial name
- NCT00503217
- Testing
- Tryptorelin
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Moderate COVID-19 Pneumonia, Severe COVID-19 Pneumonia, Pneumonia, Viral
COVID-19 Convalescent Plasma Treatment in SARS-CoV-2 Infected Patients
Due to the limitations of COVID-19 treatment and in the absence of licensed antiviral for COVID-19, the historical choice of therapeutic convalescent plasma (CP) is considered especially against RNA viruses .It was known that…
- Trial name
- NCT04474340
- Testing
- COVID-19 Convalscent Plasma
- Where
- Kuwait
- Volunteers
- 300 people
- Sponsor
- Ministry of Health, Kuwait