Clinical trials: Treatment Adherence and Compliance
HIV Infection
HIV Disclosure and Medication Adherence, a Pilot Study
The investigators believe that disclosure of HIV status could influence medication adherence. If disclosure leads to social support, adherence could be improved.
- Trial name
- RSAD-VIH-11 (NCT01621412)
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
Atelectasis, Compliance, Patient
Restoration of Pulmonary Compliance After Laparoscopic Gynaecologic Surgery Using a Recruitment Maneuver
To investigate the hypothesis that an alveolar recruitment maneuver after the release of pneumoperitoneum would restore the lung compliance to the baseline values after a laparoscopic gynaecologic surgery.
- Trial name
- NCT06203665
- Testing
- Recruitment Maneuver
- Where
- Greece
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Panagiota Griva
Patient Preference
Tradeoffs in Patient Decision Making About Rectal Cancer Treatment: Benefits Compared to Quality Of Life.
This study is aiming to look into patients' treatment preferences and their socio economic background as well as the exploration of thought processes leading to these preferences.
- Trial name
- Pathos (NCT04925154)
- Testing
- The only intervention will be the information brochure that will be given after the first questionnaire.
- Where
- Canada
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Depressive Disorders
Evaluation of a Psychoeducation Group Program for Mild/Moderate Depression
The purpose of this study is to compare the effectiveness and efficiency of doing a psychoeducational group program and the conventional treatment versus individual conventional care in patients with a mild/moderate depression…
- Trial name
- NCT00841737
- Testing
- Psychoeducational group, Control Group
- Where
- 2 sites in Spain
- Volunteers
- 192 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Medication Adherence
Effect of Community Pharmacist Intervention on Adherence to Long-Term Medications
The 4-arm factorial design RCT tested the impact of a behavioral intervention (SBI or BI), a reminder device (Pillbox), and the combination of the two on adherence in adult patients who filled a prescription for oral medications…
- Trial name
- ECO-PHIL (NCT02604901)
- Testing
- Screening and Brief Intervention (BI), Pill Box (PB)
- Where
- 2 sites in United States
- Volunteers
- 1,091 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Healthy Aging, Health Care Utilization
Annual Wellness Visits vs GRACE-augmented Annual Wellness Visits For Older Adults With High Needs - Phase 1
This study consists of three aims focused on examining the feasibility of adding the Geriatric Resources and Assessment for the Care of Elders (GRACE) model to structured Annual Wellness Visits (AWVs) to improve patient and…
- Conditions
- Healthy Aging, Health Care Utilization, Health-Related Behavior
- Trial name
- SPIRE1 (NCT06287801)
- Testing
- Annual Wellness Visit, Geriatric Resources and Assessment for the Care of Elders
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Massachusetts General Hospital
Sexually Transmitted Diseases, Safe Sex
P3 (Prepared, Protected, emPowered)
P3 (Prepared, Protected, emPowered) is an interactive smartphone app for HIV-uninfected YMSM and YTW that utilizes social networking and game-based mechanics as well as a comprehensive understanding of what constitutes "best…
- Conditions
- Sexually Transmitted Diseases, Safe Sex, Adherence, Medication
- Trial name
- P3 (NCT03320512)
- Testing
- P3, P3+, Control
- Where
- 9 sites in United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Opioid Withdrawal, Postoperative Pain
Opioid Tapering After Spine Surgery
The effect of a tapering plan combined with telephone counselling to assist patients in opioid tapering after surgery remains unexplored.
- Trial name
- NCT04140955
- Testing
- Tapering plan and telephone counselling
- Where
- Denmark
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Epilepsy, Ketogenic Dieting
Evaluation Of Strategies For Improving Ketogenic Diet Compliance
In order to increase adherence to ketogenic diet treatment, palatability of meals and diversify the foods offered to patients a ketogenic kitchen will be created.
- Conditions
- Epilepsy, Ketogenic Dieting, Compliance, Treatment
- Trial name
- NCT05112107
- Testing
- Culinary workshops
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo General Hospital
Lumbar Spinal Stenosis
Effectiveness and Safety of Korean Medicine for Lumbar Stenosis Patients With Sciatica
A prospective study investigating the effectiveness and safety in lumbar stenosis patients receiving integrative Korean medicine treatment at 3 locations of Jaseng Hospital of Korean Medicine through assessment of pain…
- Trial name
- NCT02975011
- Testing
- Herbal medicine, Chuna manipulation, Bee venom pharmacopuncture
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Jaseng Medical Foundation
Acute Lymphoblastic Leukemia
Mercaptopurine Therapeutic Drug Monitoring to Optimize the Maintenance Phase of Childhood ALL
Acute lymphoblastic leukemia (ALL) is the most common hematological malignancy in children (<18 years). The success of pediatric ALL therapy is remarkable but important challenges still need to be faced, including cure rates in…
- Trial name
- NCT05811845
- Where
- 4 sites in Italy
- Volunteers
- 250 people
- Sponsor
- IRCCS Burlo Garofolo
Alcohol Use Disorder, Alcohol Associated Liver Disease
A Digital Pill System to Measure and Support Acamprosate Adherence in Individuals With Alcohol Associated Liver Disease
This study seeks to develop and test a novel digital pill system (DPS) that measures real-time medication ingestion and pairs it with a cognitive behavioral therapy (CBT)-based intervention to provide personalized, data-driven…
- Conditions
- Alcohol Use Disorder, Alcohol Associated Liver Disease, Medications for Alcohol Use Disorder, Behavioral Medicine
- Trial name
- NCT07553377
- Testing
- AcamproSync
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Yale University
Satisfaction, Patient
Learning Excellence Program and Improvement of Quality Care
Improving the quality of care is a daily goal in pediatric intensive care units. Measuring patient and family satisfaction is recognized as an indicator of quality of care.
- Trial name
- RECOMPENSE (NCT05707195)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Advance Care Planning, Multimorbidity
ACP in Older Patients With Multimorbidity: a Randomized Pilot
Rationale A recent study into the patient perspective of patients with multiple chronic conditions in the Netherlands underlines the strain multimorbidity can put on people.
- Conditions
- Advance Care Planning, Multimorbidity, Old Age; Debility, Health Economics
- Trial name
- NCT04856202
- Testing
- Advance Care Planning interview
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Erasmus Medical Center
Osteoporosis, Postmenopausal, Osteoporosis
Quality of the Detection & Treatment of Osteoporotic Fractures in a Swiss Trauma Center
As a tertiary hospital the Traumatology department at the Kantonsspital Aarau looks after about 500 fracture patients hospitalized with an age over 50 years a year.
- Trial name
- NCT02157753
- Where
- Switzerland
- Volunteers
- 478 people
- Sponsor
- Kantonsspital Aarau
Diabetes Mellitus, Type 2 DM
Glycemic Control With Triple Pathway Approach Through Empagliflozin, Linagliptin and Metformin Combination
The efficacy and safety of a triple-pill combination therapy for advanced type 2 diabetes care. The study aims to assess the impact of 3 Oral Anti Diabetic (OAD) drugs on metabolic control, patient compliance, weight management…
- Trial name
- GLYCO-3P (NCT06862739)
- Testing
- Empagliflozin+Linagliptin+Metformin
- Where
- 2 sites in Pakistan
- Volunteers
- 800 people
- Sponsor
- Nabiqasim Industries (Pvt) Ltd
Adherence, Medication, Nonadherence, Medication
Interventions to Improve Specialty Medication Adherence
Patients deemed nonadherent to their specialty medications will be randomized to receive 8 months of patient-tailored adherence interventions and follow up from a specialty pharmacist as needed or the standard of care.
- Trial name
- NCT03709277
- Testing
- Pharmacist-Driven Intervention
- Where
- United States
- Volunteers
- 438 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Passive Smoking, Tobacco Smoke Pollution
Educational Models for Tobacco Exposure Awareness
This is a randomized controlled trial comparing the effects of peer education and traditional education on increasing knowledge and awareness of secondhand and thirdhand tobacco smoke exposure among geriatric care program…
- Conditions
- Passive Smoking, Tobacco Smoke Pollution, Health Education, Peer Group Guidance
- Trial name
- NCT07473245
- Testing
- Peer Education, traditional education
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Patient Centred Care, Compliance, Treatment
Treatment-related Quality of Life and Patient-Centred Care With Infertility
This study was conducted in a cross-sectional descriptive type with 160 infertile women who were treated in the IVF Clinic of a university hospital between July - October 2020 in order to evaluate the effect of patient-centered…
- Conditions
- Patient Centred Care, Compliance, Treatment, Infertility, Female, Quality of Life
- Trial name
- NCT05078996
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Elif Balkan
Periodontitis, Treatment Adherence
I-Smads in Periodontitis
Recently, it has been stated that Smads play an active role in all conditions where transforming growth factor-beta (TGF-β) is involved, including periodontal inflammation.
- Trial name
- NCT04846166
- Testing
- Periodontally healthy group, Periodontitis
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
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