Clinical trials: Treatment Of Obesity
Binge-Eating Disorder, Obesity
Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Medication Change for Non-Responders
This study will test the relative efficacy and effectiveness of the combination of naltrexone and bupropion (NB) medication as a treatment for binge-eating disorder (BED) in patients with obesity.
- Trial name
- NCT03946111
- Testing
- Naltrexone and Bupropion
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Yale University
Breast Cancer
Impact of Obesity on the Efficacy of Endocrine Therapy With Aromatase Inhibitors
To see the impact of obesity on the efficacy of adjuvant endocrine therapy with aromatase inhibitors in postmenopausal patients with early breast cancer in terms of: i) Locoregional recurrence ii) Distant metastases iii)…
- Trial name
- NCT01758146
- Testing
- Tamoxifen, Letrozole
- Where
- India
- Volunteers
- 412 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Obesity
A Study in People With Obesity to Test the Effects of BI 456906 Compared With Semaglutide on Glucagon Receptor Activity in the Liver
This study is open to adults with obesity. People with a body mass index (BMI) in the range from 30 to 40 kg/m2 and a body weight of 70 to 150 kg can participate in the study.
- Trial name
- NCT05202353
- Testing
- BI 456906, Semaglutide
- Where
- Netherlands
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Obesity
Predictors of Behavioral Obesity Treatment Outcomes
Socioceconomically disadvantaged individuals typically have poor outcomes in behavioral weight loss interventions, but the reasons for this are unknown.
- Trial name
- REBOOT (NCT05326477)
- Testing
- Behavioral weight loss treatment
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Obesity &Amp; Overweight, Hypertension
A Prospective Randomnised Controlled Trial Comparing Overall Patient Compliance in a Bariatric Surgical Pathway Using the Standard Versus a More Intensified and Interactive Version of the "Get Ready" Smartphone Application.
The aim of this study is to assess the impact of a newly intensified digital platform following bariatric surgery. This will be measured using several questionnaires.
- Conditions
- Obesity &Amp; Overweight, Hypertension, Obstructive Sleep Apnea (OSAS), Diabetes Mellitus ( Type 1 and Type 2)
- Trial name
- NCT07297342
- Testing
- GetReady application, Intensified GetReady application
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Sint Dimpna Ziekenhuis Geel
Obesity
Use of the Incisionless Operating Platform as a Primary Treatment for Obesity vs. Diet-Exercise Alone
This study is a multi-center, open/unblended study (3:1Treatment: Control) to evaluate the safety and effectiveness of the g-Cath EZ Suture Anchor Delivery Catheter as an early weight loss intervention compared to a diet and…
- Trial name
- MILEPOST (NCT01843231)
- Testing
- g-CathTM EZ Suture Anchor Delivery Catheter, Diet and Exercise Control Group
- Where
- 3 sites in Austria, Netherlands and 1 more
- Volunteers
- 40 people
- Sponsor
- USGI Medical
Obesity
Assessment of and Treatment Applied to Food Addiction in a Rural Healthy Behaviors Clinic
Research purpose: The purpose of this pilot study is to assess obese clients for two phenotypes, those testing positive and those testing negative for Food Addiction (FA) (Yale Food Addiction Scale, YFAS) and determining the…
- Trial name
- NCT03431831
- Testing
- Intervention Control, Counselling, Contrave
- Where
- 2 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Obesity
Daily Eating Patterns for Total Health Study
The goal of this randomized controlled trial is to learn how the time of day when calories are eaten affects weight loss in the long-term (12 months). The main aims are to learn: 1.
- Trial name
- DEPTH (NCT06455995)
- Testing
- DEPTH, DEPTH-Morning, DEPTH-Evening
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- The University of Tennessee, Knoxville
Bipolar Disorder, Obesity
The Effect of Dulaglutide as an Adjuvant Therapy on Cognitive Function in Bipolar Disorder Patients With Obesity
The primary objective of this study is to investigate the effect of dulaglutide adjuvant treatment in patients with bipolar disorder with obesity, in addition to exploring the effect of GLP-1RA on cognition of bipolar disorder.
- Conditions
- Bipolar Disorder, Obesity, Cognition
- Trial name
- NCT06331286
- Testing
- dulaglutide injection
- Where
- China
- Volunteers
- 60 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Fatty Liver, Liver Fibrosis
Efficacy and Tolerance of Treatment With DHA, Choline and Vitamin E in Children With Non-alcoholic Steatohepatitis
The purpose of this interventional study is to evaluate the efficacy and tolerability of docosahexaenoic acid (DHA), Vitamin E and Choline in children or adolescents with well-characterized and liver biopsy confirmed nonalcoholic…
- Conditions
- Fatty Liver, Liver Fibrosis, Obesity, Metabolic Syndrome
- Trial name
- NCT01934777
- Testing
- Docosahexaenoic Acid plus Vitamin E plus choline
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Obesity & Overweight
Microrandomized Trial to Optimize Use of Burden-reducing Self-monitoring Approaches in Behavioral Obesity Treatment
This clinical trial is focused on testing dietary self-monitoring strategies used in behavioral obesity treatment. The goal is to determine which self-monitoring strategies are most useful for whom, at which points in treatment…
- Trial name
- NCT07228130
- Testing
- Online Behavioral Obesity Treatment, Full Dietary Self-monitoring, Reduced-frequency Dietary Self-monitoring
- Where
- United States
- Volunteers
- 275 people
- Sponsor
- The Miriam Hospital
Non-Alcoholic Fatty Liver Disease, Obesity
Lifestyle Interventions for the Treatment of Non-alcoholic Fatty Liver Disease in Overweight and Obese Adults
Lifestyle intervention is the most important management of non-alcoholic fatty liver diseases (NAFLD) patients. Weight reductions of 5-10% can improve non-alcoholic steatosis and fibrosis.
- Trial name
- NCT03972631
- Testing
- Lifestyle education, Intensive lifestyle intervention, Hypocaloric low-carbohydrate diet plan
- Volunteers
- 292 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Obesity
A Pilot Trial of Nabilone for the Treatment of Obesity
Obesity is a serious health problem which increases the likelihood of developing other life-changing medical conditions. Despite increasing knowledge about the neural and metabolic basis of obesity, the development of effective…
- Trial name
- NCT04801641
- Testing
- Nabilone
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- Centre for Addiction and Mental Health
Weight Loss, Obesity
Development and Effectiveness of Cognitive Behavioral Therapy Based Weight Control Mobile Application "BI'KILO"
The primary purpose of this project is to observe the effects of Cognitive Behavioral Psychotherapy-based weight-loss mobile application (Bi' Kilo) in 4 essential areas (Anthropometric, Biochemical, Psychometric, Cognitive) in…
- Conditions
- Weight Loss, Obesity, Overweight and Obesity, Eating Behavior
- Trial name
- NCT06359236
- Testing
- BI'KILO Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Obesity
Sensible Treatment of Obesity in Rural Youth . . .
Project STORY (Sensible Treatment of Obesity in Rural Youth) will entail a three-arm randomized controlled trial to test the effectiveness of interventions designed to promote successful weight management in an important…
- Trial name
- NCT00248677
- Testing
- Behavioral Family-Based Intervention, Behavioral Parent-Based Intervention
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- University of Florida
Obesity, Overweight
Evaluating a Remotely Delivered Plant-Based Behavioral Weight Loss Treatment
Many individuals do not achieve clinically significant weight loss following traditional lifestyle modification interventions, potentially because weight loss is dependent upon calorie tracking compliance (to achieve calorie…
- Trial name
- NCT04892030
- Testing
- Whole Food Plant-Based Behavioral Weight Loss Treatment
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Drexel University
Childhood Obesity, Disordered Eating
Disordered Eating Risk in Pediatric Obesity Treatment Using a Digi-Physical Tool
The goal of this observational study is to evaluate the risk of developing disordered eating behavior or an eating disorder among children and adolescents with obesity who have used a digi-physical treatment tool with daily…
- Conditions
- Childhood Obesity, Disordered Eating, Binge Eating Disorder, Anorexia Nervosa
- Trial name
- NCT06807489
- Testing
- Digi-physical treatment tool
- Where
- Sweden
- Volunteers
- 312 people
- Sponsor
- Karolinska Institutet
Obesity
The Therapeutic Effects of Topiramate and Metformin on Second Generation Antipsychotics-induced Obesity
The primary aim of the study is to investigate the efficacy of metformin and topiramate on second-generation antipsychotic-induced obesity. The secondary domain we look at is the adverse effects of both drugs.
- Trial name
- NCT01384279
- Testing
- metformin, topiramate
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Beitou Armed Forces Hospital, Taipei, Taiwan
Obesity & Overweight
Feasibility and Acceptability of a Pediatric Referral to Summer Day Camps to Treat Obesity in Children From Low-Income Households
Children from low-income households have a 25-30% higher prevalence of OWOB compared to their higher-income peers. The lack of feasible and effective treatments to address obesity in children with OWOB and from low-income…
- Trial name
- NCT07464015
- Testing
- Summer Day Camp
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Central Florida
Obesity, Type 2 Diabetes
Pemf Therapy for the Management of Diabetes in Obese Patients
The Investigators previously developed pulsed electromagnetic field stimulation therapy (PEMF) for the metabolic activation of muscle and adipose tissues.
- Trial name
- PROMISE (NCT04183543)
- Testing
- Pulsed Electromagnetic Fields
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- National University Hospital, Singapore
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