Clinical trials: Treatment Of Obesity
Insulin Resistance, Polycystic Ovary Syndrome
Lactobacillus Rhamnosus and PCOS Treatment
The effect of Lactobacillus rhamnosus supplementation on body weight, hyperandrogenism and insulin resistance in overweight and obesity women with Polycystic Ovary Syndrome will be analysed.
- Conditions
- Insulin Resistance, Polycystic Ovary Syndrome, Hyperandrogenism, Obesity
- Trial name
- ProjectPCOS (NCT03902301)
- Testing
- Lactobacillus group, Dietary group
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Poznan University of Life Sciences
Obesity, Morbid
Pre- and Postoperative Cognitive Behavior Therapy for Patients Accepted for Bariatric Surgery
The purpose of this study is to investigate the relationship between the potential predictive psychological variables and success after bariatric surgery.
- Trial name
- NCT00635011
- Testing
- psychotherapy
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Helse Fonna
Obesity, Psoriatic Arthritis
Effects of Weight-loss Treatment in Obese Patients With Psoriatic Arthritis
The study is an open intervention study with the aim to determine the effects of weight-loss treatment with Low-Energy liquid Diet (LED) on disease activity, quality of life and markers of the metabolic syndrome in patients with…
- Conditions
- Obesity, Psoriatic Arthritis, Metabolic Syndrome, Psoriasis
- Trial name
- VIPsA (NCT02917434)
- Testing
- Very Low Energy Diet (VLED)
- Where
- 4 sites in Sweden
- Volunteers
- 90 people
- Sponsor
- Vastra Gotaland Region
Obesity, Diabetes
Gelesis Glycemic Index Study
A study to determine glucose and insulin responses to 50g and 100 g of carbohydrate with and without Gelesis200.
- Conditions
- Obesity, Diabetes, PreDiabetes
- Trial name
- GLIDE (NCT03124134)
- Testing
- Gelesis200
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Gelesis, Inc.
Overweight or Obesity
Effectiveness of a Digital Behavioral Intervention Program for Overweight and Obese Patients
This study applied digital technology to a comprehensive lifestyle intervention strategy to design a digital behavioural intervention programme suitable for weight reduction in overweight obese infertile patients in China, and…
- Trial name
- NCT07045272
- Testing
- Experimental
- Volunteers
- 90 people
- Sponsor
- Anhui Medical University
Renal Transplantation
Interaction Between Rimonabant and Cyclosporine and Tacrolimus
The major cause of premature death in renal transplant recipients is cardio-vascular disease. In addition, obesity is becoming a major problem in this patient population.
- Trial name
- RIMONA-PILOT (NCT00525681)
- Testing
- cyclosporine A, tacrolimus
- Where
- Norway
- Volunteers
- 18 people
- Sponsor
- University of Oslo School of Pharmacy
Obesity, Weight Loss
ReShape Vest™ for the Treatment of Obesity (Europe)
To assess the safety and effectiveness of the LGV in treating obese subjects with a BMI of 35 kg/m2 to 55 kg/m2 who have failed one or more conservative weight-reduction alternative(s), such as supervised diet, exercise, and…
- Trial name
- NCT03918564
- Testing
- Laparoscopic Gastric Vest (LGV)
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- ReShape Lifesciences
Patients Who Consented to Undergo Laparoscopic Gastric Banding Surgery for Weight Loss and Consent to Participate in This studyBMI ≥35 kg/m2, Confirmed Type 2 Diabetes Treated With Oral Agents and/or Only Diet Therapy
A Pilot Study of Metabolic Effects of Omentectomy
PROTOCOL SUMMARY Type of Study: Pilot, randomized and single center trial Test Procedure: Omentectomy Aim 1. Determine the effect of omentectomy on 1) insulin sensitivity, 2) beta cell function and 3) plasma markers of…
- Conditions
- Patients Who Consented to Undergo Laparoscopic Gastric Banding Surgery for Weight Loss and Consent to Participate in This studyBMI ≥35 kg/m2, Confirmed Type 2 Diabetes Treated With Oral Agents and/or Only Diet Therapy, Age 18-64 Years
- Trial name
- OMT (NCT00565799)
- Testing
- Omentectomy, No intervention
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- NYU Langone Health
Type 2 Diabetes Patients, Overweight and Obesity
Liraglutide-bolus vs Glargine-bolus Therapy in Overweight/Obese Type 2 Diabetes Patients (LiraGooD)
The present 24-week, prospective, open-label, randomized, multicenter, parallel group trial is carried to investigate and evaluate the efficacy and safety of Liraglutide in combination with prandial insulin therapy vs insulin…
- Conditions
- Type 2 Diabetes Patients, Overweight and Obesity, Hyperglycaemia (Diabetic)
- Trial name
- LiraGooD (NCT03087032)
- Testing
- Liraglutide, insulin glargine
- Where
- China
- Volunteers
- 164 people
- Sponsor
- The First Affiliated Hospital of Xiamen University
Heart Diseases, Obesity
Cardiovascular System in Obesity: Effect of Treatment
To determine the long-term efficacy of the combination therapy of phentermine and fenfluramine in conjunction with diet, exercise, and behavior modification in the treatment of simple, moderate obesity.
- Conditions
- Heart Diseases, Obesity, Vascular Diseases
- Trial name
- NCT00000506
- Testing
- fenfluramine, phentermine
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Overweight, Obesity
Safety and Efficacy of the BTL-703 Treatment for the Non-invasive Lipolysis
The study will evaluate safety and efficacy of the BTL-703 device for the non-invasive lipolysis.
- Trial name
- NCT03545360
- Testing
- BTL-703 (Treatment group)
- Where
- Bulgaria
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Obese Adults
Evaluation of the Axomove Therapy Medical Device to Facilitate Adapted Physical Activity for Patients With Obesity
Background: Obesity affects 18.1% of adults in France and leads to numerous chronic complications as well as functional limitations (fatigability, dyspnea).
- Trial name
- ON-TRAC (NCT07903025)
- Testing
- Axomove Therapy, Standard multidisciplinary medical care
- Where
- 8 sites in France
- Volunteers
- 184 people
- Sponsor
- Axomove
Obesity
A Study to Learn About Safety and Effects of Once-monthly Treatment With Berobenatide in Adults With Obesity Disease in Japan (VESPER-JM)
The purpose of this clinical study is to learn about safety and effects of berobenatide (PF-08653944) in adults with obesity disease, a condition in which a person has too much body fat, which can harm their health and increase…
- Trial name
- NCT07794774
- Testing
- Berobenatide
- Where
- 28 sites in Japan
- Volunteers
- 197 people
- Sponsor
- Pfizer
Asthma
Breathing & Mild Physical Exercise Therapy for Asthma
Overall goal: To apply the investigators' well defined simple, few-minute breathing/ mild physical exercise program and evaluate its efficacy/benefits for the improvement of clinico-immunological outcome in obese patients with…
- Trial name
- NCT01509443
- Testing
- Exercise
- Where
- Kuwait
- Volunteers
- 100 people
- Sponsor
- Dasman Diabetes Institute
Obese Women
The Therapeutic Effect of Catgut Embedding in Obesity
The aim of this double-blind, randomized, placebo-controlled trial is to evaluate the therapeutic effects of acupoint stimulation by catgut embedding on complexion, quality of life, lipid profile, inflammatory markers, and…
- Trial name
- NCT02276235
- Testing
- Catgut embedding group
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Taipei City Hospital
Type 2 Diabetes Mellitus, Obesity
Metabolic Effects of Duodenal Jejunal Bypass Liner for Type 2 Diabetes Mellitus
Implantation of a duodenal-jejunal endoluminal bypass liner (DJBL) has shown to induce weight loss and to improve metabolic parameters.
- Trial name
- DJBL-T2DM (NCT02800668)
- Testing
- DJBL (Duodenal jejunal bypass liner, EndoBarrier)
- Where
- Germany
- Volunteers
- 19 people
- Sponsor
- Ruhr University of Bochum
Atrial Fibrillation, Obesity
Behavioural Weight Loss Treatment for Patients with Atrial Fibrillation and Obesity in Cardiac Rehabilitation
One-in-four Canadians will be diagnosed with an abnormal heart rhythm called atrial fibrillation (AF) in their lifetime. People with AF have an increased chance of having serious medical problems like stroke and heart failure.
- Trial name
- BE-WEL in CR (NCT05230823)
- Testing
- CR with added BWLT
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Calgary
Childhood Obesity, Sleep Problems
Evaluation of Innovative School-based Interventions on Health Outcomes Among Primary School Students During Post COVID-19 Pandemic
Objectives: (1) to evaluate the feasibility of innovative school-based interventions on health outcomes (psychological well-being, depressive symptoms, anxiety symptoms, physical activity, sleep duration, and sleep quality) among…
- Conditions
- Childhood Obesity, Sleep Problems, Physical Activity
- Trial name
- WeJoy+WeHop (NCT06766890)
- Testing
- WeJoy+WeHop
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Overweight, Obesity
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
The main purpose of this study is to evaluate the efficacy and safety of eloralintide compared with placebo in participants with persistent obesity or overweight, with or without type 2 diabetes, and on stable incretin background…
- Trial name
- ENLIGHTEN-6 (NCT07392190)
- Testing
- Eloralintide
- Where
- 185 sites in United States, Australia and 12 more
- Volunteers
- 900 people
- Sponsor
- Eli Lilly and Company
Overweight and Obesity
Dietary Treatment Study of Fat Synthesis and Risk of Cardiovascular Disease
The purpose of this study is to find out how the amount of fat or sugar in a person's diet, or the number of meals eaten each day, affect the amount of fat that people's bodies make, the types of fats in the bloodstream, and how…
- Trial name
- NCT02075710
- Testing
- High sugar/meal feed, High sugar/nibble, High fat/meal feed
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
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