Clinical trials: Treatment Of Obesity
Obesity, Morbid, Surgery
Sleeve Versus Bypass in Older Patients: a Randomized Controlled Trial
The aim of the study is to compare two different bariatric procedures performed in patients with 65 years or more: gastric bypass and sleeve gastrectomy.
- Conditions
- Obesity, Morbid, Surgery, Elderly
- Trial name
- BaSE (NCT03339791)
- Testing
- Sleeve Gastrectomy, Gastric Bypass
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- University of Sao Paulo General Hospital
Weight Loss, Adverse Events
The IGBallon (R) - for Use in the Treatment of Obesity
This study is a prospective, non-randomized, open-label, single-center study. The aim of this study is to assess the safety of the IGballoon in the human body.
- Conditions
- Weight Loss, Adverse Events, Comorbidities
- Trial name
- IGBallon (NCT07647991)
- Testing
- IGBalloon
- Where
- Austria
- Volunteers
- 5 people
- Sponsor
- Medical University of Vienna
Obesity, Postoperative Bariatric Surgery
Lung Ultrasound Evaluation of the Effects of PEEP and Recruitment Strategies Adjusted for Intraoperative Dynamic Compliance on Postoperative Respiratory Complications in Obese Patients Planned for Laparoscopic Surgery
This study aims to investigate the effects of the personalized application of respiratory pressures applied to patients undergoing laparoscopic bariatric surgery when they are connected to a ventilator under general anesthesia…
- Conditions
- Obesity, Postoperative Bariatric Surgery, Laparoscopic Surgery, Individualized PEEP Treatment Strategy
- Trial name
- NCT06994780
- Testing
- dynamic compliance guided PEEP titration
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
PreDiabetes, Obesity, Morbid
Effectiveness of Dapagliflozin for Weight Loss
Mexico has one of the highest prevalence of obesity, reported on 32.4 percent of people over 20 years old, with a prevalence of obesity class III of 1.8 percent on males and 4.1 percent on females.
- Conditions
- PreDiabetes, Obesity, Morbid, Diabetes Mellitus, Type 2
- Trial name
- NCT03968224
- Testing
- Dapagliflozin/Metformin, Metformin
- Where
- Mexico
- Volunteers
- 160 people
- Sponsor
- Centro Medico Nacional Siglo XXI IMSS
Bariatric Surgery Candidate, Obesity
A Preoperative Cognitive Behavioural Therapy Program Based on Self-determination Theory for Bariatric Surgery Candidates
The objective of this study is to evaluate the impact of a pre-surgical intervention program based on Cognitive and Behavioural Emotional Therapies, on the degree of dietary restriction of patients who are candidates for…
- Trial name
- ACRoBAT (NCT03976674)
- Testing
- Cognitive Behavioural Therapy (CBT)
- Where
- France
- Volunteers
- 94 people
- Sponsor
- Lille Catholic University
Overweight and Obesity
Teaching Novel Values-Based Skills to Improve Long-Term Weight Loss
This NIDDK funded R01 project is a randomized controlled clinical trial to compare the efficacy of an intervention based on Acceptance and Commitment Therapy (ACT) and a Self-Regulation (SR) intervention on weight loss…
- Trial name
- NCT04256850
- Testing
- Acceptance and Commitment Therapy (ACT), Self-Regulation (SR)
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Childhood Obesity
Community-based Program to Treat Childhood Obesity
This study will evaluate the effectiveness of a comprehensive community based program on reducing excess weight in children and teens. This study will recruit 150 participants between the ages of 6-12 and 13-17.
- Trial name
- NCT01374646
- Testing
- JOIN Intervention
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- UnitedHealth Group
Obesity
A Study to Determine the Feasibility of Online Recruitment of People Using an Anti-Obesity Medication for Weight Loss
This observational study is designed to determine the feasibility of recruitment from a digital research community of people using an anti-obesity medication for weight loss to understand willingness to consent to survey research…
- Trial name
- COSMOS-DIGITAL (NCT06761703)
- Testing
- TAP® Micro Select Device (Touch Activated Phlebotomy)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Amgen
Obesity, Hypertension
Efficacy of Candesartan on Reducing Blood Pressure in Insulin-Resistant, Obese Patients With Hypertension.
The purpose of this study is to determine the efficacy of candesartan, once daily (QD), combined with hydrochlorothiazide to lower blood pressure in insulin-resistant, obese patients with hypertension.
- Trial name
- NCT00775814
- Testing
- Candesartan and Hydrochlorothiazide, Hydrochlorothiazide (HCT)
- Where
- 24 sites in Germany
- Volunteers
- 188 people
- Sponsor
- Takeda
Obesity
Effect of 2-year Administration of CP-945,598 on Weight Loss Efficacy and Safety.
The purpose of this study is to examine the long-term weight loss and safety of CP-945,598 in obese adults
- Trial name
- NCT00396448
- Testing
- CP-945,598 Treatment B, CP-945,598 Treatment A
- Where
- 61 sites in United States, Argentina and 9 more
- Volunteers
- 1,253 people
- Sponsor
- Pfizer
Overweight
Xinju Xiaogao Prescription Study on Overweight
Xinju Xiaogao prescription and 10% of it in the treatment of adiposity (stagnation of QI causing phlegm retention)clinical study
- Trial name
- XJXG (NCT01142076)
- Testing
- Xinju Xiaogao Prescription
- Volunteers
- 140 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Obstructive Sleep Apnea, Obesity
Novel Inhibitors of Lipolysis in the Treatment of Lipid a Glucose Metabolism in Obstructive Sleep Apnea Syndrome
Obstructive sleep apnea syndrome (OSA) represents highly prevalent (typically overlooked, undiagnosed and untreated) disorder significantly increasing cardiovascular, cancer and overall mortality as well as increasing the risk of…
- Trial name
- NORRIS (NCT05245240)
- Testing
- Dietary and physical intervention
- Where
- Czechia
- Volunteers
- 50 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Obesity & Overweight, Obesity (Disorder)
Examining Valence-based Effects in Self-Monitoring Feedback Messages
The purpose of this research study is to learn how to identify the most effective ways to provide weekly feedback on participants' progress toward intervention goals during a weight loss program.
- Trial name
- NCT07292389
- Testing
- Positive Reinforcement, Positive Reinforcement + Areas for Change
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Obesity Hypoventilation Syndrome
Respiratory Muscle Strength in Patients With Obesity Hypoventilation Syndrome (OHS) or With a Precursor of the Disease
Using an extensive set of both volitional and non-volitional tests of respiratory muscle function and strength it is the aim of this study to identify potential determinants for the development of obesity hypoventilation to…
- Trial name
- NCT03854058
- Testing
- magnetic phrenic nerve stimulation
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
Obesity
Dexmedetomidine to Treat Bariatric Surgery-associated Pain
Obesity represents one of the most important public health issues according to the World Health Organization and it has reached epidemic proportions globally.
- Trial name
- NCT02880540
- Testing
- Fentanyl, Morphine, Dexmedetomidine
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Janelle Vaughns
Obesity, Diabetes Mellitus, Type 2
Efficacy, Safety, and Tolerability of Tirzepatide in Real-World Conditions in Paraguay.
This is a prospective cohort study evaluating the efficacy, safety, and tolerability of tirzepatide under real-world conditions in the Paraguayan population.
- Trial name
- REAL-TIRZEPY (NCT07588438)
- Testing
- Tirzepatide (LIPOLESS de Laboratorio de Productos Eticos C.E.I.S.A.)
- Where
- Paraguay
- Volunteers
- 160 people
- Sponsor
- Las Rías Medical Center
Endometrioid Endometrial Adenocarcinoma
A Study to Estimate Early Clinical Efficacy Signals of GLP-1 Agonist Administration in Conjunction With Levonorgestrel Intrauterine Device in Obese Patients With Endometrioid Intraepithelial Neoplasia
This study will explore the use of glucagon-like peptide 1 receptor agonist (GLP-1RA) used concurrently with levonorgestrel intrauterine device in patients with poor surgical candidacy for a hysterectomy or patients who are…
- Trial name
- NCT07107334
- Testing
- Glucagon-like peptide 1 receptor agonist
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Florida
Obesity, Dyslipidemias
European Trial About Effect of RimoNabant on Abdominal Obese Patients With dysLipidemia
Primary : To determine the effect of Rimonabant 20 mg on changes in, HDL-Cholesterol (HDL-C), triglyceride levels over a period of 12 months when prescribed with a mild hypocaloric diet in abdominally obese patients with…
- Trial name
- ETERNAL (NCT00412698)
- Testing
- rimonabant
- Where
- 15 sites in Czechia, Finland and 13 more
- Volunteers
- 645 people
- Sponsor
- Sanofi
Cardiovascular Risk Factor, Diabetes Mellitus, Type 2
Evaluation of a Physical Activity Referral Scheme
The study will evaluate the effectiveness of a co-developed exercise referral scheme. Participants will be recruited to one of three groups 1. Co-developed exercise referral scheme, 2. Usual care exercise referral scheme, 3.
- Conditions
- Cardiovascular Risk Factor, Diabetes Mellitus, Type 2, Anxiety, Depression
- Trial name
- NCT03490747
- Testing
- Physical activity referral scheme, Usual care exercise referral scheme
- Where
- United Kingdom
- Volunteers
- 68 people
- Sponsor
- Paula Watson
Pediatric Obesity, Executive Function
Acceptance-based Care for Child Eating and Physical Activity Treatment
The purpose of this study is to develop and pilot test a new type of patient-centered, family-based treatment for children aged 8-12 with obesity and their caregivers.
- Conditions
- Pediatric Obesity, Executive Function, Self-Regulation
- Trial name
- ACCEPT (NCT03368716)
- Testing
- Acceptance-based Behavioral Treatment (ABBT)
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
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