Clinical trials: Treatment Of Obesity
Obesity, Diabetes Mellitus
Type 2 Diabetes Primary Prevention for At Risk Girls
Purpose: To evaluate two approaches to prevent obesity and type 2 diabetes in young girls. The Need: We are experiencing an epidemic of childhood obesity.
- Conditions
- Obesity, Diabetes Mellitus, Pre Diabetes
- Trial name
- NCT00063674
- Testing
- Nutrition Education, After-school dance class
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Adolescent Obesity
Mobile Health Intervention to Identify Early Responders to Treatment in Adolescent Obesity
Background: The Expert Committee on the Assessment, Prevention and Treatment of Child and Adolescent Overweight and Obesity recommends a staged based approach to the management of adolescents with overweight and obesity from…
- Trial name
- NCT03561597
- Testing
- Mobile health intervention
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- KK Women's and Children's Hospital
Pediatric Obesity, Dyslipidemia
Treatment of Overweight and Obese Children -Using the "Holbaek-Method" in a Municipality Based Treatment Program.
In the present study the effect of a community-based treatment of overweight and obese children is analyzed. The treatment-method is based on the principals and the method used in the Children Obesity Clinic in the Pediatric…
- Conditions
- Pediatric Obesity, Dyslipidemia, Hypertension, Diabetes
- Trial name
- NCT02013843
- Testing
- Community-based treatment of overweight and obesity
- Where
- Denmark
- Volunteers
- 1,007 people
- Sponsor
- Holbaek Sygehus
Pulmonary Disease, Chronic Obstructive, Obesity Hypoventilation Syndrome
Treatment of Metabolic Alkalosis With Acetazolamide. Effect on the Length of Mechanical Ventilation.
The purpose of this study is to analyze whether the treatment of metabolic alkalosis with acetazolamide in intubated patients with chronic obstructive pulmonary disease (COPD) or with obesity hypoventilation syndrome (OHS)…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Obesity Hypoventilation Syndrome, Metabolic Alkalosis
- Trial name
- TRAMA (NCT01499485)
- Testing
- Acetazolamide
- Where
- 8 sites in Spain
- Volunteers
- 140 people
- Sponsor
- Hospital Son Llatzer
Sleep Apnea, Obstructive, Obesity Hypoventilation Syndrome (OHS)
Evaluation of An Optical Measurement Algorithm Combined With Patient and Provider Input to Reduce Mask Exchanges During Initial Positive Airway Pressure Therapy
Continuous positive airway pressure and non-invasive ventilation are common treatment modalities for obstructive sleep apnea, central sleep apnea, and chronic alveolar hypoventilation from a variety of causes.
- Conditions
- Sleep Apnea, Obstructive, Obesity Hypoventilation Syndrome (OHS), Sleep Apnea Syndromes
- Trial name
- NCT04688125
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Mayo Clinic
Obesity, Phentermine Withdrawal
Long-term Phentermine Pharmacotherapy: An Investigation for Symptoms of Dependence, Cravings, or Withdrawal
Phentermine, an amphetamine congener, is the most widely used anti-obesity drug in the U.S. Although phentermine is the agent-of-choice among physicians specializing in obesity treatment, the use of this drug for obesity…
- Trial name
- PC-II (NCT01402674)
- Testing
- Abrupt cessation of phentermine pharmacotherapy
- Where
- 2 sites in United States
- Volunteers
- 269 people
- Sponsor
- Center for Weight Management, California
Diabetes Mellitus, Type 2, Obesity
Effect of Dairy Consumption on Glycemic Control, Body Weight and Cardiovascular Risk Factors
The aim of this study is to determine the relationship between the percentage of calories from dairy intake and long-term glycemic control and weight maintenance in patients with type 2 diabetes who participate in an intensive…
- Trial name
- NCT02896140
- Testing
- Type 2 diabetes in WhyWAIT Program
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Joslin Diabetes Center
Obesity
Ginger Capsules for the Chronic Treatment of Obesity
Regarding its complex pathogenesis and clinic-epidemiological meaning, different strategies are needed for the treatment of obesity.
- Trial name
- NCT02742194
- Testing
- Dry extract of ginger
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Federal University of Minas Gerais
Obesity
Study of Serum Markers for Cardiovascular Risk in Obese Youth and Impact of Lifestyle and Medication Intervention
In Protocol #2, we will select 30 obese pubertal and 30 obese prepubertal subjects with an abnormal cytokine profile (i.e. fibrinogen and/or hsCRP concentration greater than or equal to 2 Standard Deviations (SD) above the mean…
- Trial name
- NCT00139477
- Testing
- Metformin, Dietary modification with caloric restriction, Establishment of exercise protocol
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Obesity, DM
Lap-Band Surgery on Adolescents for Safety and Efficacy
This study is to demonstrate the safety and efficacy of the use of the LAP-BAND surgery in the morbidly obese adolescent population.
- Trial name
- ALAGB (NCT00587301)
- Testing
- Lap-Band
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- NYU Langone Health
Depression
Efficacy of Metformin as an Adjunct to Standard Antidepressant Therapy in Treating Depression Among Obese Patients
To evaluate the efficacy of metformin as an adjunct therapy in improving depressive symptoms and metabolic markers in newly diagnosed obese depressed patients on standard antidepressant therapy.
- Trial name
- NCT06707012
- Testing
- Metformin Hydrochloride
- Where
- 2 sites in Pakistan
- Volunteers
- 140 people
- Sponsor
- Fazaia Ruth Pfau Medical College
Obesity
Portion Control Treatment for Obesity
To date, no studies have been published assessing the effectiveness of portion control interventions in a primary care setting. The investigators will conduct a pilot study to assess the effectiveness of an intervention including…
- Trial name
- NCT01451554
- Testing
- portion control plate, Usual Care
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obesity
Predictors of Behavioral Obesity Treatment Outcomes
Socioceconomically disadvantaged individuals typically have poor outcomes in behavioral weight loss interventions, but the reasons for this are unknown.
- Trial name
- REBOOT (NCT05326477)
- Testing
- Behavioral weight loss treatment
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Overweight or Obesity; Type 2 Diabetes, Weight Loss Maintenance
AI-assisted Multi-domain Lifestyle Versus Tirzepatide for Weight Loss Maintenance in Adults With Type 2 Diabetes (AIM-MAINTAIN)
This is a randomized controlled trial to compare the effect of AI-assisted multi-domain lifestyle and continued tirzepatide on body weight loss maintenance.
- Trial name
- NCT07555730
- Testing
- AI assisted multi-domain lifestyle intervention, Tirzepatide
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Huazhong University of Science and Technology
Child Obesity, Social Determinants of Health
Addressing Social Determinants of Health in Child Obesity Treatment Using Community Health Workers
The goal of this small pilot study is to test the feasibility of combining a three-month intervention of working with a community health worker (CHW) to address social risk factors for patients prior to beginning a group weight…
- Trial name
- NCT06520657
- Testing
- Community Health Worker, Child weight management intervention, Standard of Care referral to resources
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Children's Mercy Hospital Kansas City
Fatty Liver, Liver Fibrosis
Efficacy and Tolerance of Treatment With DHA, Choline and Vitamin E in Children With Non-alcoholic Steatohepatitis
The purpose of this interventional study is to evaluate the efficacy and tolerability of docosahexaenoic acid (DHA), Vitamin E and Choline in children or adolescents with well-characterized and liver biopsy confirmed nonalcoholic…
- Conditions
- Fatty Liver, Liver Fibrosis, Obesity, Metabolic Syndrome
- Trial name
- NCT01934777
- Testing
- Docosahexaenoic Acid plus Vitamin E plus choline
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
OSA - Obstructive Sleep Apnea, Obesity
A Study of XW003 in Obese Participants With Obstructive Sleep Apnea But Not Receive Positive Airway Pressure Therapy
The aim of the study is to assess the efficacy and safety of XW003 injections in obese participants with OSA but not receiving PAP
- Trial name
- NCT07387094
- Testing
- XW003 injection
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Hangzhou Sciwind Biosciences Co., Ltd.
Obesity, Poor Glycemic Control
The Consumption of Beef on Appetite and Cognitive Function
The purpose of the main study is to determine whether the daily consumption of protein-rich meals containing high quality, lean beef products improves appetite control and cognitive function during a weight maintenance diet.
- Conditions
- Obesity, Poor Glycemic Control, Dietary Interventions
- Trial name
- NCT02614729
- Testing
- Standard Protein-Plant, Even Distribution (SP-PLANT-EVEN), Standard Protein-Beef, Even Distribution (SP-BEEF-EVEN), High Protein-Beef, Even Distribution (HP-BEEF-EVEN)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Deficiency, Vitamin D, Obesity
Dosage Calculation for Vitamin D Treatment
Severe vitamin D deficiency can be treated with oral loading doses of cholecalciferol. Our objective was to determine how to calculate the quantity of cholecalciferol needed for supplementation by single algorithm, usable on a…
- Trial name
- NCT02186106
- Testing
- Cholecalciferol
- Volunteers
- 31 people
- Sponsor
- Bispebjerg Hospital
Obesity, Type 2 Diabetes
Effects of Different Surgical Methods to Treat Obesity
Obese patients have an increased risk for developing severe metabolic disorders. This risk can only partly be reduced by weight reduction.
- Conditions
- Obesity, Type 2 Diabetes, Insulin Sensitivity
- Trial name
- DEOSH (NCT01785134)
- Testing
- Omentectomy, Gastric bypass operation
- Where
- 4 sites in Sweden
- Volunteers
- 81 people
- Sponsor
- Karolinska Institutet