Clinical trials: Treatment Of Obesity
Morbid Obesity
Laparoscopic Gastric Bypass Versus Sleeve Gastrectomy to Treat Morbid Obesity
Bariatric surgery in the treatment of morbid obesity is associated with long-term weight-loss and decreased overall mortality. Long-term results have been reported for laparoscopic gastric bypass procedures but the long-term…
- Trial name
- SLEEVEPASS (NCT00793143)
- Where
- 4 sites in Finland
- Volunteers
- 240 people
- Sponsor
- Turku University Hospital
Pediatric Obesity
Benefit of the Chalaxie Pedagogical Tool in the Management of Overweight or Obese Children With Intellectual Disability : a Pilot Monocentric Prospective Study.
The main objective of this study is to determine the benefit of the Chalaxie pedagogical evaluation tool in the management of overweight or obese children with intellectual disability.
- Trial name
- CHALAXIE (NCT05007249)
- Testing
- Use of the Chalaxie pedagogical evaluation tool
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
Overweight and Obesity
Episodic Future Thinking and Weight-Loss
Family-based treatments (FBT) for obesity have been shown to be effective in achieving significant weight reductionin overweight or obese children and parents [Altman \& Wilfley, 2015].
- Trial name
- NCT03731325
- Testing
- Episodic Future Thinking Group
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- State University of New York at Buffalo
Obesity
Inspiratory Muscle Training After Gastroplasty
The purpose of this study is to assess the effect of post-operative inspiratory muscle training on muscle strength and endurance in patients with obesity submitted to gastroplasty.
- Trial name
- NCT01084447
- Testing
- inspiratory muscle training, control group
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo
Obesity, Exercise
Research on Prevention, Intervention and Mechanisms of Obesity and Its Comorbidities
Obesity and lack of physical activity are associated with an increased risk of many chronic diseases and accelerate the processes associated with aging.
- Conditions
- Obesity, Exercise, Nutrition, Healthy
- Trial name
- Obesity (NCT05211817)
- Testing
- Complex lifestyle intervention, Carnosine
- Where
- Slovakia
- Volunteers
- 60 people
- Sponsor
- Slovak Academy of Sciences
Obesity & Overweight
Feasibility and Acceptability of a Pediatric Referral to Summer Day Camps to Treat Obesity in Children From Low-Income Households
Children from low-income households have a 25-30% higher prevalence of OWOB compared to their higher-income peers. The lack of feasible and effective treatments to address obesity in children with OWOB and from low-income…
- Trial name
- NCT07464015
- Testing
- Summer Day Camp
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Central Florida
Type 2 Diabetes Mellitus (T2DM), Obesity & Overweight
The Transit Bipartition With the Use of a Metallic Anastomosis Clip and Circular Fundocorporeal Gastroplication
This study evaluates a new surgical device - the Metallic Anastomotic Clip (MAC) - for performing a laparoscopic bypass gastroenteroanastomosis with entero-enteric anastomosis (transit bipartition / "dual-path" procedure) in…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Obesity & Overweight, Marginal Ulcer (Peptic) or Erosion, Leakage, Anastomotic
- Trial name
- MACBIPARTFCG (NCT07495020)
- Testing
- Laparoscopic transit bipartition with Metallic Anastomotic Clip and Circular Fundocorporeal Gastroplication, Laparoscopic transit bipartition (gastroenteroanastomosis and entero-enteric anastomosis) use the Metallic Anastomotic Clip and with sleeve gastrectomy, laparoscopic duodenal transit bipartition using the Metallic Anastomotic Clip with circular fundocorporeal gastroplication without gastrectomy
- Where
- Kazakhstan
- Volunteers
- 90 people
- Sponsor
- The Society of Bariatric and Metabolic Surgeons of Kazakhstan
Obesity, Hypoandrogenism
Clomiphene Citrate for the Treatment of Obesity Related Male Hypogonadism
Hypogonadism is a clinical condition that can be associated with obesity in man. Controversy exists regarding if its a condition that needs to be treated.
- Trial name
- NCT02380755
- Testing
- Clomiphene Citrate
- Where
- Brazil
- Volunteers
- 78 people
- Sponsor
- University of Sao Paulo
Obesity, Diabetes Mellitus, Type 2
The Potential of Dapagliflozin Plus Exenatide in Obese Insulin-resistant Patients
This is a 28-week, multi-center, randomized, double-blind, placebo-controlled trial to study a potential synergistic effect of Dapagliflozin plus Exenatide once-weekly in combination with high-dose intensive insulin therapy…
- Trial name
- NCT03419624
- Testing
- Dapagliflozin 10mg, Exenatide 2 mg [Bydureon], Insulin
- Where
- 4 sites in Germany
- Volunteers
- 13 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Sarcopenic Obesity, Sarcopenia
Lifestyle Modifications for the Treatment of Sarcopenic Obesity
This study evaluates the addition of a high-protein energy-restricted diet to exercise in the treatment of sarcopenic obesity in people aged 65 and over.
- Conditions
- Sarcopenic Obesity, Sarcopenia, Obesity
- Trial name
- NCT02379026
- Testing
- Protein Drink/Diet, Exercise, Vitamin D3
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Queen Margaret University
Overweight, Obesity
Preventing Overweight in USAF Personnel: Minimal Contact Program
The prevalence of overweight in the United States Air Force (USAF) is about 22%. The objective of this study is to compare the effectiveness of a minimal contact behavioral therapy plus usual care group(MCBT+UC) using a…
- Trial name
- NCT00417599
- Testing
- Lifestyle Intervention, control group
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Hepatitis
Treating Nonalcoholic Steatohepatitis (NASH) With Metformin
Nonalcoholic Steatohepatitis (NASH) is associated with progressive liver disease, fibrosis, and cirrhosis. Although the cause of NASH is unknown, it is often associated with obesity, type 2 diabetes, and insulin resistance.
- Trial name
- NCT00063232
- Testing
- Metformin
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
GERD, Obesity
Long Term Outcomes of Bariatric Patients Treated With Surgery or Endoscopy
GERD is common in the obese population. Bariatric procedures are the mainstay of therapy for these patients. Bariatric procedures can be surgical (Roux-en-Y gastric bypass and Vertical sleeve gastrectomy) or endoscopic…
- Trial name
- ROSE (NCT03705416)
- Testing
- Endoscopy, Surgery
- Where
- 6 sites in United States
- Volunteers
- 250 people
- Sponsor
- Johns Hopkins University
Obesity, Morbid
Two Hypoabsorption Techniques for the Treatment of Type III Obesity (OASIS)
This study aims to compare the percentage of total weight lost in long-term follow-up after two surgical interventions (SADIS and OAGB) in patients with morbid obesity BMI between 45-49.9.
- Trial name
- OASIS (NCT05948852)
- Testing
- metabolic surgery (SADIS and OAGB)
- Volunteers
- 96 people
- Sponsor
- Consorci Sanitari Integral
Obesity
Deep Brain Stimulation for the Treatment of Obesity
The purpose of this clinical study is to investigate the safety and efficacy of deep brain stimulation (DBS) as a treatment option for obesity.
- Trial name
- NCT01512134
- Testing
- Deep Brain Stimulation Device
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Ali Rezai, MD
Hepatitis
Treating Nonalcoholic Steatohepatitis With Pioglitazone
Nonalcoholic steatohepatitis (NASH) is a common liver disease that resembles alcoholic hepatitis but occurs in persons who drink little or no alcohol.
- Trial name
- NCT00062764
- Testing
- Actos (Pioglitazone)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity
Barriers to Treatment in Obese Adolescents
The purpose of this study is to identify significant racial and ethnical differences in risk factors for development of obesity and weight loss in adolescents in Central Virginia
- Trial name
- NCT00167830
- Testing
- Motivational Interviewing, Strength and Cardiovascular Conditioning, Food selection and portion control
- Where
- United States
- Volunteers
- 292 people
- Sponsor
- Virginia Commonwealth University
Obesity (BMI>30)
Resistance Training to Prevent Muscle Loss During Treatment With Tirzepatide
Incretin-based pharmacotherapies induce significant weight loss and represent a paradigm shift in obesity treatment. However, particularly fast weight loss may be accompanied by a significant loss of muscle mass, which is…
- Trial name
- RESIST (NCT07777575)
- Testing
- Dual GIP/GLP-1 Receptor Agonist Tirzepatide, Resistance Training
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Technical University of Munich
Obesity, Overweight
Optimal Dietary Treatment of Obese Adults
Recent decades have shown an alarming increase in obesity. Obesity is associated with high costs for both the individual and for society. It is therefore important to prevent and treat obesity.
- Trial name
- OPDIOS (NCT01685957)
- Testing
- Standard dietary treatment (STD), "Ned i vaegt" (NIV), "Verdens bedste kur" (VBK)
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Hospitalsenheden Vest
Pre-diabetes
Preventing Diabetes in the Deep South: Extending Partnerships and Adapting Interventions to Reach Rural Communities at High Risk.
Diabetes is responsible for a huge and growing burden of patient suffering and social costs, and the impact of this disease is shared disproportionately by minorities and in rural resource-challenged communities, particularly in…
- Trial name
- NCT04343872
- Testing
- Receive lifestyle modification alone, Metformin therapy
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
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