Clinical trials: Treatment Refusal
COVID-19 Infection
Evaluation of an Interactive Risk Information Tool to Increase COVID-19 Vaccination Incidence in Vaccine-hesitant People
Coronavirus (COVID-19) vaccines have saved millions of lives since release and remain a key tool in the fight against the pandemic.
- Trial name
- iWILL (NCT05193903)
- Testing
- Simulation, Text
- Where
- Germany
- Volunteers
- 1,188 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Vaccine Hesitancy
Motivational Interviewing for Vaccine Uptake in Latinx Adults
The goal of this clinical trial is to test whether modified behavioral health services, integrating motivational interviewing, will reduce vaccine hesitancy and increase uptake for the COVID-19 and influenza vaccines among Latinx…
- Trial name
- MIVacuna (NCT06062056)
- Testing
- EHR alert, Motivational Interviewing, Warm hand off to nurse
- Where
- 2 sites in United States
- Volunteers
- 3,698 people, healthy volunteers welcome
- Sponsor
- Boston College
Endodontic Treatment of Primary Teeth
Endodontic Treatment of Necrotic Primary Teeth With Guedes Pinto Paste: A Randomized Clinical Trial
The maintenance of primary teeth until their exfoliation has been one of the main purposes of Pediatric Dentistry, are they representing the fundamental basis for proper occlusion of the permanent dentition.
- Trial name
- NCT02216942
- Testing
- Endodontic treatment using Vitapex, Endodontic treatment using Guedes Pinto
- Where
- Brazil
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Fausto Medeiros Mendes
Influenza, Human, Vaccine Hesitancy
Conversational AI for Adult Flu Vaccination Decisions
This randomized trial tests whether an online guide combining short evidence cards with an AI-guided conversation increases flu-vaccination intention among US adults who haven't decided whether to get a flu vaccine this season.
- Trial name
- NCT07896850
- Testing
- Flu vaccination guide, Accident safety guide
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Calypta Systems, Inc.
Vaccination Refusal, COVID-19
COVID-19 Vaccine Uptake Trial
The goal of this study is to assess the best COVID-19 vaccine uptake strategy among students, staff and household members that have not been vaccinated.
- Trial name
- NCT05419232
- Testing
- Short Message Service (SMS) + Website Link Strategy, Phone Call with Peer Strategy
- Where
- 8 sites in United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Covid-19 Vaccine, Vaccine Hesitancy
PROmotion of COvid-19 VA(X)Ccination in the Emergency Department - PROCOVAXED
The goal of this research is to increase COVID-19 vaccine acceptance and uptake in vulnerable populations whose primary (and often only) health care access occurs in emergency departments (ED Usual Source of Care Patients).
- Trial name
- PROCOVAXED (NCT05142332)
- Testing
- Covid-19 vaccine education materials
- Where
- 7 sites in United States
- Volunteers
- 541 people
- Sponsor
- University of California, San Francisco
Vaccine Hesitancy
Increasing Vaccine Uptake Among Adolescents in the Rural South
The benefits of adolescent vaccines are well known for preventing meningococcal infection and human papillomavirus (HPV)-related pre-cancerous lesions.
- Trial name
- INVEST (NCT04999267)
- Testing
- INVEST
- Where
- 2 sites in United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Duke University
HIV Infections, Adolescent Development
Tailored Motivational Interviewing Implementation-Effectiveness Trial in Multidisciplinary Adolescent HIV Care Settings
The goal of this study is to test a multi-faceted Tailored Motivational Interviewing Implementation intervention (TMI), based on the Dynamic Adaptation Process (DAP) to scale up an Evidence-based Practice (EBP) in…
- Conditions
- HIV Infections, Adolescent Development, Care Eliciting Behavior, Patient Non-Compliance
- Trial name
- TMI (NCT03681912)
- Testing
- Competency: 12-Item Motivational Interviewing (MI) Coach Rating Scale (CRS), Randomized Guided Development of COPs with an internal facilitator after one year of implementation., CoP development without internal facilitation.
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Florida State University
Vaccine Hesitancy, Vaccine Refusal
Vaccine Hesitancy: A Survey of Pediatric Clinicians
The purpose of this study is to explore the experiences and perceptions of District VI pediatric clinicians on parental vaccine hesitancy and vaccine refusal.
- Trial name
- NCT01098825
- Testing
- web-based survey
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Vaccine Refusal
Clinic-based HPV and COVID-19 Vaccine Promoting Intervention for AfAm Adolescents in Alabama
In this 30-month study, the investigators propose to develop a culturally appropriate vaccine confidence intervention, targeting positive change related to HPV vaccine uptake behavior and reducing sentiments of hesitancy towards…
- Trial name
- NCT04604743
- Testing
- Intervention, TBN
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Vaccination Hesitancy, Human Papillomavirus Vaccination
Testing the Persuasiveness of Pro-inoculation Arguments
The investigators will recruit a national sample of parents of 7-10-year-olds to complete an argument strength ranking for either a simple forwarding message or between 3 and 6 randomly selected arguments from an overall set of…
- Conditions
- Vaccination Hesitancy, Human Papillomavirus Vaccination, Vaccine Refusal
- Trial name
- NCT05804825
- Testing
- Argument inoculation messages, Simple forewarning message
- Where
- United States
- Volunteers
- 523 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
COVID-19, Vaccine Refusal
CATCH-UP Vaccines: Engaged Approaches to Testing in Community/Healthcare Settings for the Underserved (COVID-19)
Oklahoma has high COVID-19 incidence, particularly among underserved minority and rural Oklahomans. Oklahoman's are also reporting SARS-CoV-2 vaccine hesitancy and signs of slowing vaccine uptake, with increased hesitancy among…
- Trial name
- NCT05236270
- Testing
- Text Message, Motivational Interviewing, Electronic Educational Message with Tailored Questions/Prompts
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
COVID-19, Vaccine Uptake
Addressing Vaccine Hesitancy and Increasing COVID-19 Vaccine Uptake Among African American Young Adults in the South
The study staff will conduct a hybrid type 1 effectiveness implementation 2-arm trail with 360 Black young adults from Alabama, Georgia, and North Carolina.
- Trial name
- NCT05490329
- Testing
- Tough Talks COVID
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Florida State University
Covid19, Vaccine Refusal
COVID-19 Vaccine Hesitancy Among African Americans
Coronavirus disease 2019 (COVID-19) has created a "state of emergency" for African Americans in the US. Recent findings indicate 31% of adults self-reported "wait and see" of the COVID-19 vaccine, of which 16% were African…
- Conditions
- Covid19, Vaccine Refusal, Communication
- Trial name
- NCT04801030
- Testing
- YourCoViDVaxFacts
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Meharry Medical College
Bipolar Disorder
Customized Medication Adherence Enhancement for Treating Adults With Bipolar Disorder
In this study, patients with bipolar disorder who do not take their medications as prescribed will receive specialized education and therapy treatment to determine whether the specialized treatment is effective in helping…
- Trial name
- NCT00763919
- Testing
- Psychoeducation module, Substance abuse module, Improved communication/rapport with provider module
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Case Western Reserve University
Chronic Obstructive Pulmonary Disease (COPD), Pulmonary Rehabilitation
Factors Associated With Acceptance of Home-Based Pulmonary Telerehabilitation in COPD
Pulmonary rehabilitation improves symptoms, exercise capacity, and quality of life in people with chronic obstructive pulmonary disease (COPD), but access and participation may be limited by travel, organizational, logistical…
- Trial name
- ACCEPT-TR (NCT07747571)
- Testing
- No intervention
- Where
- France
- Volunteers
- 50 people
- Sponsor
- ADIR Association
COVID-19, Trust
Community-Led COVID-19 Testing Intervention to Address Mistrust
The goal of this adapted intervention study is to assess how community-led group discussions about health-related topics may alter beliefs and intentions regarding healthcare recommendations, such as COVID-19 testing and…
- Trial name
- NCT07166770
- Testing
- Community-led discussion
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Old Dominion University
School Phobia
Multi-family Therapy and School Refusal: an Exploratory Study With Adolescents and Their Families
The purpose of this study is to determine whether multi-family therapy is effective in the treatment of school refusal with anxiety in adolescence.
- Trial name
- Multi-Fast (NCT05432323)
- Testing
- Multi-family therapy
- Where
- France
- Volunteers
- 74 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19, Vaccine Hesitancy
COVID-19 Vaccine Hesitancy Among Nurses
The purpose of this study is to investigate the correlation of intention to receive COVID-19 vaccine, recommendation behavior, and 5C psychological antecedents among Nurses.
- Conditions
- COVID-19, Vaccine Hesitancy, Vaccination, Nurses
- Trial name
- NCT05212974
- Testing
- Questionnaires
- Where
- Taiwan
- Volunteers
- 4,258 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Treatment Refusal
PEG-ASP, Etoposide and Gemcitabine for Natural Killer/T Lymphoma
Extranodal natural killer/T-cell lymphoma (ENKTL) is an aggressive form of non-Hodgkin's lymphoma and shows extremely poor survival.
- Trial name
- NCT02705508
- Testing
- Gemcitabine, etoposide, Pegaspargase
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Sun Yat-sen University