Clinical trials: Treatment With Proton Beam Radiation Therapy
Helicobacter Infections, Bacterial Infections
Study of the Safety and Effectiveness of Rabeprazole in Treatment of Helicobacter Pylori Infection in Adults.
The purpose of the study is to confirm the safety and effectiveness of rabeprazole in the treatment of adult patients with Helicobacter pylori (H. pylori) infection in routine clinical practice.
- Trial name
- NCT00216450
- Testing
- rabeprazole sodium
- Volunteers
- 80 people
- Sponsor
- Janssen Cilag Pharmaceutica S.A.C.I., Greece
Gastroesophageal Reflux, Heartburn
A Study of the Safety of Rabeprazole Administered to Adults With Gastroesophageal Reflux Disease (GERD)
The purpose of the study is to confirm the safety and effectiveness of rabeprazole in the treatment of patients with erosive or ulcerative gastroesophageal reflux disease (GERD) in routine primary health care.
- Trial name
- NCT00216489
- Testing
- rabeprazole sodium
- Volunteers
- 191 people
- Sponsor
- Janssen Cilag Pharmaceutica S.A.C.I., Greece
GERD, Gastroesophageal Reflux Disease
Thread-Embedding Acupuncture as an Adjunct to Proton Pump Inhibitor Therapy for Gastroesophageal Reflux Disease
This study aims to evaluate the effectiveness of thread-embedding acupuncture combined with omeprazole in patients with gastroesophageal reflux disease (GERD) presenting with the traditional medicine pattern of Liver-Stomach…
- Trial name
- NCT07797959
- Testing
- Thread-Embedding Acupuncture
- Where
- Vietnam
- Volunteers
- 50 people
- Sponsor
- University of Science Ho Chi Minh City
Breast Carcinoma, Esophageal Carcinoma
Data Collection for the Assessment of Acute and Late Normal Tissue in Patients Treated With Proton Therapy
This study collects information on the side effects of proton therapy and detailed information on the proton therapy treatment plan itself.
- Conditions
- Breast Carcinoma, Esophageal Carcinoma, Genitourinary System Carcinoma, Head and Neck Carcinoma
- Trial name
- NCT00991094
- Testing
- Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- M.D. Anderson Cancer Center
Uveal Melanoma
Influence of Oral Treatment With Citicoline for the Prevention of Radiation Optic Neuropathy in Patients Treated for Uveal Melanomas With Proton Beam Therapy
Proton beam irradiation is the treatment of choice for uveal melanomas. It has favorable results in causing tumor regression while preserving the eye.
- Trial name
- NCT01338389
- Testing
- CITICOLINE
- Where
- 2 sites in France
- Volunteers
- 21 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Pancreatic Cancer
Neoadjuvant Accelerated Short Course Radiation Therapy With Proton Beam and Capecitabine for Resectable Pancreatic Cancer
A standard treatment for pancreatic cancer is radiation therapy plus chemotherapy after surgery. Radiation therapy and chemotherapy are commonly given for up to six weeks.
- Trial name
- NCT00438256
- Testing
- Proton Beam Radiation, Capecitabine
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Non-erosive Gatroesophageal Reflux Disease
Treatment Response of Maintenance Dose of Proton Pump Inhibitor in Patients With Nonerosive Gatroesophageal Reflux Disease
For ERD(erosive reflux disease), which pathogenesis is mainly the acid reflux mechanism, primary treatment is therefore PPI. However, NERD(non-erosive reflux disease) is much more complex than ERD and there are more factors…
- Trial name
- NCT03436914
- Testing
- PPI
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- Yonsei University
Heartburn
Efficacy/Safety of Lansoprazole in Patients With Frequent Heartburn
Heartburn, a burning sensation in the chest or throat, occurs in many patients when acidic stomach contents move into the esophagus from the stomach.
- Trial name
- NCT00389948
- Testing
- Lanzoprazole
- Where
- 28 sites in United States
- Volunteers
- 576 people
- Sponsor
- Novartis
Breast Cancer
Partial Breast Proton Therapy for Early Stage Breast Cancer
The purpose of this is to determine the efficacy and toxicity of proton therapy when used to deliver partial breast radiotherapy in patients with early stage breast cancer with low or intermediate risk factors.
- Trial name
- NCT01310530
- Testing
- Proton Beam Radiotherapy
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Loma Linda University
Malignant Brain Glioma
Spectroscopic MRI Guided Proton Therapy in Assessing Metabolic Change in Pediatric Patients With Brain Tumors
This trial studies how well spectroscopic magnetic resonance imaging (MRI) guided proton therapy works in assessing metabolic change in pediatric patients with brain tumors.
- Trial name
- NCT04908709
- Testing
- Magnetic Resonance Spectroscopic Imaging, Proton Therapy
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- Emory University
Gastric Ulcer Associated With Helicobacter Pylori
Additive Effect of Endonase on Eradication Rate of First Line Therapy for Helicobacter Pylori
Endonase, a kind of protease, is known to cause both extensive degradation of mucins and a reduction in mucus viscosity. As part of the search for more effective forms of therapy against H.
- Trial name
- NCT01645761
- Testing
- Endonase
- Where
- South Korea
- Volunteers
- 112 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Peptic Ulcer
Compare Efficacy of Gastric Acid Suppression by Oral and Intravenous Administration of Esomeprazole in Patients With Peptic Ulcer
The purpose of this study is to compare the gastric acid suppression profile among different regimen (Oral Vs Intravenous)of administration of proton pump inhibitor - Esomeprazole by 24hours intragastric pH monitoring.
- Trial name
- NPH (NCT00471029)
- Testing
- esomeprazole
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Pamela Youde Nethersole Eastern Hospital
Thoracic Neoplasm, Liver Cancer
Mechanically-assisted Ventilation in the Treatment of Moving Tumours With Photon and Proton Therapies
Mechanical ventilation can be used to impose a completely regular pattern of breathing frequency and inflation volume on the patient for as long as required.
- Conditions
- Thoracic Neoplasm, Liver Cancer, Ventilator Lung, Radiotherapy; Complications
- Trial name
- NCT03226925
- Testing
- Non-invasive mechanically-assisted ventilation, Dynamic MRI acquisition, Planning 4D-CT
- Where
- Belgium
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Patients With Typical Symptoms of GERD (GERD Q >= 8)
Proton Pump Inhibitor Empirical Treatment in Management of Outpatients With Gastroesophageal Reflux Disease.
China Survey of Proton Pump Inhibitor Empirical Treatment in Management of Outpatients with Gastroesophageal Reflux Disease
- Trial name
- NCT02606851
- Where
- 10 sites in China
- Volunteers
- 1,000 people
- Sponsor
- AstraZeneca
Laryngopharyngeal Reflux
Safety and Efficacy of Lansoprazole 30mg Twice Daily in Treatment of Laryngitis Associated With Gastroesophageal Reflux
The purpose of this study is to determine whether Lansoprazole 30mg taken twice daily is effective in the treatment of laryngitis due to gastroesophageal reflux.
- Trial name
- NCT00369265
- Testing
- Lansoprazole, Sugar pill
- Where
- 3 sites in United States
- Volunteers
- 18 people
- Sponsor
- American Institute for Voice and Ear Research
Prostate Adenocarcinoma
Mild Hypofractionation With Proton Therapy or IMRT for Intermediate-Risk Prostate Cancer
This is a study to first establish feasibility of the study and then to register the treatment data of adult patients with a diagnosis of intermediate risk of prostate cancer presenting for definitive radiation treatment with…
- Trial name
- NCT01352429
- Testing
- Proton Therapy, IMRT
- Where
- 2 sites in United States
- Volunteers
- 303 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Gastroesophageal Reflux Disease
Efficacy And Safety Of PF-00885706 For The Relief Of Symptoms In Subjects With Gastro-esophageal Reflux Disease (GERD)
To understand the dose-response characteristics of PF-00885706 for efficacy in terms of symptomatic relief when used as add-on treatment to esomeprazole 20mg (standard proton pump inhibitor [PPI] treatment), in subjects with…
- Trial name
- NCT00730665
- Testing
- PF-00885706, Esomeprazole
- Where
- 38 sites in Belgium, Brazil and 5 more
- Volunteers
- 81 people
- Sponsor
- Pfizer
Prostate Cancer, Radiotherapy Side Effect
Protons vs. Photons for High-risk Prostate Cancer
The purpose of this study is to assess late gastro-intestinal side-effects comparing proton therapy to photon therapy in high-risk prostate cancer patients receiving whole pelvic irradiation.
- Trial name
- NCT05350475
- Testing
- Proton therapy, Photon therapy
- Where
- 7 sites in Denmark
- Volunteers
- 102 people
- Sponsor
- University of Aarhus
NPC Patients, Nasopharyngeal Cancinoma (NPC)
Prospective Immuno-Radiomic Profiling in Nasopharyngeal Carcinoma Treated With Proton or Photon Chemoradiotherapy
To prospectively investigate and integrate radiomic and immunologic signatures in patients with nasopharyngeal carcinoma (NPC) treated with either proton or photon radiotherapy, with the aim of identifying biomarkers associated…
- Trial name
- IMPRINT (NCT07232680)
- Testing
- Proton chemoradiotherapy, Photon chemoradiotherapy
- Where
- Taiwan
- Volunteers
- 500 people
- Sponsor
- Cheng-En Hsieh
Prostate Cancer
Quality of Life Study for Prostate Cancer Patients
The goal of this behavioral research study is to look at patients' quality of life after treatment or management for prostate cancer.
- Trial name
- NCT00561444
- Testing
- Questionnaire
- Where
- 3 sites in United States
- Volunteers
- 1,051 people
- Sponsor
- M.D. Anderson Cancer Center