Clinical trials: Tremor
Functional Movement Disorder, Functional Neurological Disorder
Tremor Retrainer Software Application for Functional Tremor
The purpose of this clinical trial is to learn about the Tremor Retrainer smartphone application and Simplified Functional Movement Disorder Rating Scale in patients with functional tremor.
- Conditions
- Functional Movement Disorder, Functional Neurological Disorder, Functional Neurological Symptom Disorder
- Trial name
- NCT06257069
- Testing
- Tremor Retrainer Smartphone Application
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Virginia
Essential Tremor
Cerebellar Research in Ultrasound Stimulation
Experiment 1: Modulation of Physiological Tremor in Healthy Volunteers Thirty healthy volunteers will undergo TUS targeting the dentate nucleus in a randomized, double-blinded crossover design.
- Trial name
- CERBERUS (NCT07508696)
- Testing
- Transcranial focused ultrasound delivered to the dentate nucleus using the NeuroFUS Pro by Brainbox, Transcranial focused ultrasound delivered to the ventricles (control) using the NeuroFUS Pro by Brainbox
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Tremor, Limb
Deep Brain Frameless Radiosurgery for Drug Resistant Invalidating Tremor. Dose Escalation Pilot Study
The gamma knife radiosurgical thalamotomy to treat many movement disorders is recently becoming a new and well defined treatment paradigm.
- Trial name
- PRDBRS2 (NCT02585583)
- Testing
- Thalamotomy
- Where
- Italy
- Volunteers
- 8 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Essential Tremor, Parkinson's Disease (PD)
Attention and Eye Movement in Parkinson's Disease
The goal of this observational and interventional study is to understand how therapeutic deep brain stimulation (DBS) affects attention, perception and cognition in participants with Parkinson's disease (PD) and non-PD movement…
- Conditions
- Essential Tremor, Parkinson's Disease (PD), Dystonias
- Trial name
- NCT06899022
- Testing
- Normal therapeutic DBS, Reduced current DBS, Reduced frequency DBS
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Parkinson Disease, Essential Tremor
Comparison of the Electric Plasma Surgical Tool "PlasmaBlade" for Replacement of the Deep Brain Stimulation (DBS) Devices With Conventional Surgery
The deep brain stimulation is surgical technique used for the Parkinson's disease, essential tremor, dystonia, epilepsy, and psychiatric diseases.
- Conditions
- Parkinson Disease, Essential Tremor, Dystonia, Epilepsy
- Trial name
- NCT05535556
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
Ataxia - Other, Dystonia Disorder
Stimulation of the Dentate Nucleus of the Cerebellum for the Treatment of Refractory Spasticity With or Without Dystonia
Electrical stimulation (DBS) through electrodes implanted in the dentate nucleus of the cerebellum for the treatment of tremor intractable with medication, dystonia due to cerebrovascular disease (stroke), sequelae of traumatic…
- Conditions
- Ataxia - Other, Dystonia Disorder, Tremor, Essential, Choreatic Disorder
- Trial name
- DN_DBS (NCT07231302)
- Testing
- Analytical observation
- Volunteers
- 20 people
- Sponsor
- Kleber Paiva Duarte
Parkinson's Disease, Essential Tremor
Deep Brain Stimulation (DBS) Data Base Study
The primary goal of this study is to evaluate and compare outcomes, trends, and effectiveness of both awake and asleep Deep Brain Stimulation (DBS) surgical treatments, target selection, targeting accuracy and outcomes in…
- Trial name
- NCT01909531
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Essential Tremor
1-Octanol to Treat Essential Tremor
This study will evaluate the safety and effectiveness of the food additive 1-octanol for treating essential tremor. This disorder, which is an involuntary shaking, usually of the hands, has no satisfactory treatment.
- Trial name
- NCT00001986
- Testing
- 1-Octanol
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Essential Tremor
Efficacy of Pramipexole Extended Release in the Treatment of Essential Tremor
Aim of the study is to perform a double-blind, crossover, placebo-controlled multicenter study evaluating the efficacy of pramipexole on essential tremor.
- Trial name
- NCT01441284
- Testing
- pramipexole
- Where
- 2 sites in Hungary
- Sponsor
- University of Pecs
Essential Tremor
Image-Guided DBS Programming
The objective of this study is to compare the effects of image-guided programming algorithm using various image segmentations vs standard clinical programming on reduction of tremor and patient satisfaction.
- Trial name
- NCT07433699
- Testing
- programming a, programming b
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
Essential Tremor, Dystonia
The Development of a System for Measurement of Tremor
The goal of this clinical trial is to develop a system which can be used to measure movements in people with Essential Tremor (with or without dystonia).
- Trial name
- NCT05956223
- Testing
- Virtual Reality measurement of essential tremor and dystonia
- Where
- Australia
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- The Bionics Institute of Australia
Essential Tremor
Continuous Tremor Assessment During Daily Activities
The specific aim of this study is to evaluate if tremor severity and quality of life can be improved more using continuous home monitoring along with traditional assessments versus traditional assessments alone.
- Trial name
- NCT01978080
- Testing
- Kinesia HomeView
- Where
- 2 sites in United States
- Volunteers
- 39 people
- Sponsor
- Great Lakes NeuroTechnologies Inc.
Tremor, Limb
The Trans-cutaneous Effects on Physiological Tremor Entertainment During tACS
Transcranial alternating current stimulation (tACS) is a noninvasive neuromodulation method that works by passing alternating electric current between electrodes where at least one of them is attached to the head.
- Trial name
- NCT04065022
- Testing
- tACS at tremor frequency
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- KU Leuven
Essential Tremor
Transcranial Ultrasound Therapy of Essential Tremor
Context. Essential tremor (ET) is a common disease, disabling in severe forms and resistant to drug treatment. In patients with severe ET, invasive neurosurgical technique such as deep brain stimulation of the Ventral…
- Trial name
- ULTRABRAINTher (NCT04074031)
- Testing
- Transcranial Ultrasound Therapy (Exablate® 4000 Type 1.1)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Parkinson Disease, Tremor
The Effect of Vibrotactile Stimulation on Parkinson's Tremor
Tremor in Parkinson's disease is a common and highly burdensome symptom. Recent evidence shows that areas in the brain that are underlying Parkinson's tremor overlap with those that respond to somatosensory stimulation.
- Trial name
- NCT05152836
- Testing
- Vibrotactile stimulation at tremor frequency, Vibrotactile stimulation at tremor frequency*1.5, Vibrotactile stimulation at continuous stimulation
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- Donders Centre for Cognitive Neuroimaging
Essential Tremor
Stereotactic Radiosurgery in the Treatment of Essential Tremor
The goal of this interventional study is to evaluate the effectiveness of treatment using stereotactic radiosurgery in the treatment of essential tremor in adult patients
- Trial name
- EASIER (NCT06821906)
- Testing
- Stereotactic Radiosurgery
- Where
- Poland
- Volunteers
- 42 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Essential Tremor
Trial of Cannabis for Essential Tremor
This is a pilot trial to evaluate the safety and efficacy of a combined oral formulation of THC and CBD in patients with Essential Tremor.
- Trial name
- NCT03805750
- Testing
- CBD/THC
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of California, San Diego
Tremor
Intravenous Dexmedetomidine for Treatment of Shivering During Cesarean Section Under Neuraxial Anesthesia
The purpose of this study is to determine whether dexmedotomidine is effective in the treatment of shivering associated with neuraxial anesthesia during cesarean delivery.
- Trial name
- NCT02384343
- Testing
- Dexmedetomidine, Normal saline
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- St. Justine's Hospital
Voice Disorders
Brain Mapping of Voice Control
Some voice disorders are caused by uncontrolled muscle actions that affect the larynx or voice box. The purpose of this study is to understand 1) how the brain controls voice production; 2) how changes in sensation within the…
- Trial name
- NCT00066911
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Dystonia, Tremor
Repetitive Transcranial Magnetic Stimulation (rTMS) for Dystonia and Tremor
The study will include subjects diagnosed with Dystonic Tremor (DT), Essential Tremor (ET), and healthy controls in the age range of 21-80 years. Electroencephalography (EEG) will be used as the primary outcome measure.
- Trial name
- NCT04299087
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS), Control group
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Florida