Clinical trials: Trigeminal Neuropathy
Trigeminal Neuralgia, Headache Disorders
Botulinum Toxin Type A Block of the Sphenopalatine Ganglion in Trigeminal Neuralgia. Safety Issues.
Trigeminal neuralgia is one of the strongest pains known to humans. Some patients do not have enough effect with the available pharmaceutical treatments and are offered surgery.
- Trial name
- NCT02662972
- Testing
- Botulinum Toxin Type A
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Norwegian University of Science and Technology
Trigeminal Neuralgia, Trigeminal Neuralgia, Idiopathic
CT-guided vs Fluoroscopy-guided Trigeminal Ganglion Radiofrequency Thermocoagulation for Idiopathic Trigeminal Neuralgia
The goal of this clinical trial is to compare the effectiveness and safety of CT-guided versus fluoroscopy-guided trigeminal ganglion radiofrequency thermocoagulation (TG-RFT) in treating idiopathic trigeminal neuralgia (TN) in…
- Trial name
- NCT06620172
- Testing
- CT-guided Radiofrequency Thermocoagulation (RFT), Fluoroscopy-guided Radiofrequency Thermocoagulation (RFT)
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Zagazig University
Mandibular Nerve Injury
Study on the Risk of Inferior Alveolar Nerve Damage During Lower Third Molar Surgery
Objective The present study aimed to evaluate which factors were statistically associated with a greater probability of inferior alveolar nerve (IAN) damage during lower third molar surgery.
- Trial name
- NCT04807946
- Testing
- lower third molar extraction
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Trigeminal Neuralgia
Analgesic Effect of Ultrasound Guided Maxillary Nerve Block in Trigeminal Neuralgia
This is a study about the dynamics and effects of ultrasound guided maxillary nerve block in trigeminal neuralgia
- Trial name
- NCT06129071
- Testing
- US guided block of maxillary nerve
- Where
- Croatia
- Sponsor
- Varazdin General Hospital
Migraine Disorders, Facial Pain Disorder, Cluster Headache, Trigeminal Neuralgia, Trigeminal Autonomic Cephalalgias
Sphenopalatine Ganglion Pulsed Radiofrequency Treatment Outcomes
Purpose of the Study: This study aims to evaluate the clinical effectiveness and long-term outcomes of "Sphenopalatine Ganglion (SPG) Pulsed Radiofrequency (PRF)" treatment in patients with chronic headaches and facial pain.
- Trial name
- SPG-PRF (NCT07370142)
- Testing
- Pulsed Radiofrequency of the Sphenopalatine Ganglion
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Ankara City Hospital Bilkent
Injury of Trigeminal Nerve, Surgery
Sensory Retraining Facilitates Sensory Recovery After Mandibular Nerve Injury
The purpose of this study is to determine whether sensory retraining exercise could improve lip numbness caused by bilateral sagittal split of mandible.
- Conditions
- Injury of Trigeminal Nerve, Surgery, Mandibular Prognathism
- Trial name
- NCT01586598
- Testing
- sensory retraining protocol
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Inferior Alveolar Nerve Injuries
Traditional vs Orthodontic Extraction of Impacted Teeth Related to the Inferior Alveolar Nerve
The aim of this clinical study was to compare the effects of traditional and orthodontic extraction methods on postoperative nerve damage in impacted third molars associated with the inferior alveolar nerve.
- Trial name
- NCT06270784
- Testing
- Traditional Extraction, Orthodontic Extraction
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Marmara University
Inferior Alveolar Nerve Injury, Nerve Injury
Platelet-rich Fibrin and Grooving for Sagittal Split Osteotomy
Sagittal split osteotomy (SSO) is a common operation done to move the mandible to correct dentofacial deformities and obstructive sleep apnea (OSA).
- Conditions
- Inferior Alveolar Nerve Injury, Nerve Injury, Neurosensory Disorder, Mandibular Nerve Injury
- Trial name
- NCT04706182
- Testing
- Platelet-rich fibrin (PRF), Proximal segment grooving (PSG)
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Jesse Han
Trigeminal Neuropathy, Traumatic
Botulinum Toxin Injections for Oral Neuropathic Pain
Peripheral painful traumatic trigeminal neuropathy (PPTTN) are poorly relieved by existing treatments which in addition induce many adverse effects.
- Trial name
- TRIGTOX (NCT03555916)
- Testing
- BOTOX®, Allergan
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Facial Neuralgia, Pain
Studies of Dextromethorphan and Topiramate to Treat Oral and Facial Pain
This study will evaluate the safety and effectiveness of two drugs-dextromethorphan and topiramate-in treating orofacial (mouth and face) pain.
- Conditions
- Facial Neuralgia, Pain, Trigeminal Neuralgia
- Trial name
- NCT00001725
- Testing
- Dextromethorphan
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Trigeminal Neuralgia, Gasserian Ganglion; Lesion
Masseter Muscle Thickness in Gasser Ganglion Radiofrequency Treatment
Trigeminal neuralgia is common painful disorder in pain medicine clinics. Gasserian ganglion radiofrequency thermocoagulation is one of the treatment option in patients with trigeminal neuralgia in refractory cases.
- Trial name
- NCT06278194
- Testing
- Gasserian Ganglion Radiofrequency Thermocoagulation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Trigeminal Neuralgia
Botulinum Toxin Type A for Injection (HengLi®) in the Treatment of Trigeminal Neuralgia
To evaluate the efficacy of different dosing regimens of Botulinum Toxin Type A for Injection (HengLi®) in the treatment of trigeminal neuralgia (TN), so as to determine the optimal dosing regimen of the best administration…
- Trial name
- NCT06410859
- Testing
- Botulinum Toxin Type A for Injection,also known as "HengLi®"
- Where
- China
- Volunteers
- 240 people
- Sponsor
- LKGS_277
Trigeminal Neuralgia, Microvascular Decompression
Impact of Teflon Technique on Recurrence After Microvascular Decompression for Trigeminal Neuralgia
The study aims to see if shredded Teflon placed away from the trigeminal nerve is equally effective in pain control in Trigeminal Neuralgia while minimizing the risks of pain recurrence due to granuloma formation when this…
- Conditions
- Trigeminal Neuralgia, Microvascular Decompression, Teflon
- Trial name
- NCT07046247
- Testing
- Microvascular decompression for trigeminal neuralgia
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- University of Valencia
Trigeminal Neuralgia (TN)
Developing a Clinical Prediction Model for Adverse Outcomes in Percutaneous Trigeminal Ganglion Balloon Compression
This clinical study aims to investigate adverse outcomes following percutaneous balloon compression (PBC) of the trigeminal ganglion, establish a predictive model, and assess the probability of postoperative complications.The…
- Trial name
- NCT06998420
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Affiliated Hospital of Nantong University
Chronic Pain, Trigeminal Neuralgia
Regional-anaesthesiological Infiltration Techniques for the Management of Chronic Pain: a Retrospective Study
There is a significant debate whether local infiltration techniques may be a method to treat complicated chronic pain syndromes, e.g. refractory headache.
- Conditions
- Chronic Pain, Trigeminal Neuralgia, Cluster Headache, Post-Zoster Neuralgia
- Trial name
- RetroBlock (NCT03066037)
- Testing
- regional-anaesthesiological infiltration
- Where
- Germany
- Volunteers
- 83 people
- Sponsor
- Charite University, Berlin, Germany
Trigeminal Neuralgia
Comparative Study inTreatment of Trigeminal Neuralgia
This study aims to evaluate the results of percutaneous radiofrequency rhizotomy and the effectiveness of microvascular decompression for the treatment of trigeminal neuralgia and Comparing between them according the different…
- Trial name
- NCT04801407
- Testing
- percutaneous radiofrequency trigeminal rhizotomy, Microvascular decompression of the trigeminal nerve
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
Trigeminal Neuralgia
Resting-State fMRI Study of Functional Connectivity After Gamma Knife Radiosurgery in Trigeminal Neuralgia
Trigeminal neuralgia is a severe chronic pain condition with a major impact on quality of life. Although Gamma Knife radiosurgery is an established treatment for pharmacoresistant trigeminal neuralgia, its mechanisms of action…
- Trial name
- DOCTRINE (NCT07357025)
- Testing
- Resting-State Functional MRI
- Volunteers
- 28 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Trigeminal Neuralgia
Greater Occipital Nerve and Cervical Region Injection in Patients With Trigeminal Neuralgia
The aim of this study is to investigate the efficacy of greater occipital nerve block and cervical injections with lidocaine
- Trial name
- NCT04505280
- Testing
- Lidocaine 1% Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Trigeminal Neuralgia
The Efficacy and Safety of Pulsed Radiofrequency Combined With Continuous Radiofrequency for the Trigeminal Neuralgia
Trigeminal neuralgia is a very painful condition, and radiofrequency therapy is reserved for patients who are resistant or intolerant to pharmacological therapy.
- Trial name
- PRFCRF (NCT04174443)
- Testing
- High-voltage pulsed radiofrequency, Low-temperature continuous radiofrequency
- Where
- China
- Volunteers
- 146 people
- Sponsor
- Beijing Tiantan Hospital
Trigeminal Neuralgia, Rhizotomy
Trigeminal Evoked Responses to Improve Rhizotomy
Trigeminal neuralgia (TGN) is a debilitating pain syndrome where electrical, shock- like jolts of pain affect the face. Trigeminal somatosensory evoked potentials (TSEPs) provide a promising modality for measuring the trigeminal…
- Trial name
- NCT05738096
- Testing
- TSEP + rhizotomy surgery, TSEPs recording only
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Minnesota