Clinical trials: Triglycerides
Type 2 Diabetes
Effects of Pramlintide on Endogenous Production of Very-low-density-lipoprotein (VLDL)-Triglyceride and Glucose in the Post Prandial State in T2DM
Diabetes affects almost 21 million people in the United States. In this study we will test a drug called Pramlintide(Symlin), and see how it works to lower blood sugar and fat levels after a meal.
- Trial name
- NCT00732147
- Testing
- Pramlintide acetate
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Healthy Adults
Bioavailability of Fish Oils: Emulsified Versus Capsular Triglyceride
The primary objective of this investigation is to determine the relative percentage and rate of incorporation of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and total omega-3 (n-3) fatty acids after ingestion of 4…
- Trial name
- NCT01488747
- Testing
- Coromega Omega-3 Squeeze, Coromega Nectar, Barleans Swirl
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Obesity, Dyslipidemia
Meta-analyses of the Effect of Sucrose Versus High Fructose Corn Syrup on Cardiometabolic Risk
The rise in high fructose corn syrup (HFCS) consumption over the past 40 years since its introduction as a popular sweetener in the United States has led to much concern regarding its contribution to the rise in obesity (1)…
- Conditions
- Obesity, Dyslipidemia, Prediabetes, Dysglycemia
- Trial name
- NCT02702479
- Testing
- High Fructose Corn Syrup, Sucrose
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Cardiovascular Diseases
Mechanism of Action of Vichy Catalan Water
Water consumption is essential to maintain hydration and good health. Sodium-bicarbonated mineral waters are reported to have beneficial digestive and hypocholesterolemic properties.
- Trial name
- NCT01334840
- Testing
- Bicarbonated mineral water, Mineral water low in mineral content (control)
- Where
- Spain
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- National Research Council, Spain
Obesity, Postprandial Lipemia
Acute Effects of Dietary Proteins on Postprandial Lipemia, Incretin Responses and Subclinical Inflammation in Obese Subjects
The purpose of this study is to determine the effects of dietary protein on blood lipids and gut hormones after a fat-rich meal.
- Conditions
- Obesity, Postprandial Lipemia, Atherosclerosis, Inflammation
- Trial name
- NCT00863564
- Testing
- Caseine, Cod, Gluten
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Triacylglycerol Digestion
The Effect of Alginate on Carbohydrate and Fat Digestion in a Mixed Meal
This study will investigate the effect of an extract of brown seaweed, called alginate, on fat digestion. The extract has been cooked into sausages and the alginate sausages will be compared to the same sausages that do not…
- Trial name
- NCT03860337
- Testing
- Alginate Sausage, Control Sausage
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Dyslipidemias, Atherosclerosis
Dyslipidemia Prevalence, Perception, Treatment, and Awareness in the Tunisian Population
ATERA Survey is a national cross sectional observational study, aiming to determine the prevalence of dyslipidemia and other conventional risk factors for CHD (Coronary Heart Disease), the relationship between environmental and…
- Conditions
- Dyslipidemias, Atherosclerosis, Households, Survey, Family Life
- Trial name
- ATERASurvey (NCT03799185)
- Where
- Tunisia
- Volunteers
- 13,610 people, healthy volunteers welcome
- Sponsor
- Association Tunisienne d'Etude & de Recherche sur l'Athérosclérose
Hypertriglyceridemia, Insulin Resistance
Predictors of Response to Fenofibrate
Fenofibrate is one of the best options for treating hypertriglyceridemia. In the majority of patients, fenofibrate lowers triglycerides (TG) by 24-55% and improves HDL- and LDL-cholesterol.
- Trial name
- PreFar (NCT01023750)
- Testing
- Fenofibrate
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cardiac Event, Klinefelter Syndrome
TyG Index Levels in Klinefelter Syndrome
It is well known that the frequency of cardiometabolic diseases are increased in patients with Klinefelter Syndrome. The triglyceride-glucose index (TyG index) is a simple surrogate marker of insulin resistance and is also…
- Conditions
- Cardiac Event, Klinefelter Syndrome, Endothelial Dysfunction
- Trial name
- NCT05014997
- Testing
- no intervention
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Physical Conditioning, Human, Lipid Metabolism
Capoeira Training Decrease Plasma Triglycerides
Background: Among the risk factors associated with aging, a special highlight has been attributed to cardiovascular dysfunctions, insulin resistance, central obesity and dyslipidemia, which is marked by low levels of cholesterol…
- Conditions
- Physical Conditioning, Human, Lipid Metabolism, Aged
- Trial name
- NCT03868878
- Testing
- Capoeira training
- Where
- Brazil
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do vale do São Francisco
Acute Coronary Syndrome
Lipid Profile in Acute Coronary Syndrome
This study aims to assess the TG/Hdl-c ratio in patients with acute coronary syndrome as a novel marker of atherosclerosis.
- Trial name
- NCT05126043
- Testing
- Triglycerides/high density lipoprotein ratio
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Diabetic Kidney Disease, Diabetes Mellitus, Type 2
Possible Ameliorating Effect of N- Acetylcysteine (NAC) on Type-II Diabetes Induced Nephropathy
The study is focused on the possible improving effect of N-acetylcysteine on nephropathy of type-2 diabetic patients. Study design: Prospective clinical based study.
- Conditions
- Diabetic Kidney Disease, Diabetes Mellitus, Type 2, Diabetic Nephropathies
- Trial name
- (NAC) (NCT04531163)
- Testing
- N Acetylcysteine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Hypertriglyceridemia
Effect of Candida Rugosa Lipase on Serum Triglyceride Lowering
The primary objective of this study was to evaluate the safety and tolerability of 3 doses of fungal lipase in the treatment of adults with mildly elevated serum triglycerides.
- Trial name
- NCT05295134
- Testing
- Candida cylindracea lipase (225,000 FIP lipase units per day), Candida cylindracea lipase (450,000 FIP lipase units per day), Candida cylindracea lipase (675,000 FIP lipase units per day)
- Where
- Ireland
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- BIO-CAT, Inc.
Prediabetes, Insulin Resistance
Food and Metabolism Study
In this study, Investigators are interested in looking at the influence of eating avocados regularly, which are rich in healthy fats, fibers, and unique carbohydrates, on triglyceride and glucose metabolism in people with…
- Conditions
- Prediabetes, Insulin Resistance, Triglycerides, Lipids Metabolism
- Trial name
- FAM (NCT07624500)
- Testing
- Avocado meal plan, Control meal plan
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Obesity, Overweight and Obesity
Ketones Supplementation and Postprandial Lipemia
This study determines whether different forms of ketones supplemented prior to a meal lower the triglyceride (fat) content in the blood of overweight and obese individuals.
- Conditions
- Obesity, Overweight and Obesity, Overweight, Triglycerides High
- Trial name
- NCT03729934
- Testing
- Ketone Ester, Ketone Salt
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
LDL Cholesterol, Triglycerides
Safety and Efficacy of a Natural Health Product in Reducing Cholesterol and Triglyceride Levels.
The purpose of this study is to assess the safety and efficacy of a natural health product among participants with elevated LDL cholesterol and triglyceride levels.
- Trial name
- NCT01028274
- Testing
- Investigational Product 1, Investigational Product 2
- Where
- Canada
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Nordic Pharma, USA
Cardiovascular Diseases, Lipid Disorder
SRMA of the Effect of Soy Milk vs Cow's Milk on Cardiometabolic Outcomes
Dairy consumption has shown associations with decreased incidence of cardiometabolic diseases. With the growing interest in plant-based eating, and the mounting evidence for the cardiovascular benefits of plant forward diets…
- Conditions
- Cardiovascular Diseases, Lipid Disorder, Metabolic Disease, Non-Alcoholic Fatty Liver Disease
- Trial name
- NCT05637866
- Testing
- Soy milk
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Waist Circumference, Triglycerides
Oral Supplementation With a Black Pepper Extract
This study is a randomized, placebo-controlled, double-blind, two-arm trial of N=94 apparently healthy men and women to be recruited at a single investigational center in Northeast Ohio. Subjects will attend three study visits.
- Conditions
- Waist Circumference, Triglycerides, Appetite, Inflammation
- Trial name
- NCT05199012
- Testing
- Black pepper extract
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- The Center for Applied Health Sciences, LLC
Cardiovascular Disease
Effects of Almonds on Cardiovascular Risk Factors
The purpose of this research is to build the evidence base for approval of FDA health claims related to almonds and cardiovascular disease.
- Trial name
- ALD (NCT01101230)
- Testing
- Almonds
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Penn State University
Low Mood
Effect of a Nutritional Supplement on Mental Wellness in Adults
Trillions of microbes reside in human gut and constitute "gut microbiota". Composition of these microbes and substances produced by them play an important role in human health and wellness.
- Trial name
- NCT06058364
- Testing
- Intervention 1 - Triglyceride
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Pharmavite LLC