Clinical trials: Triglycerides
Elevated Triglycerides, Diabetes
Fructose-Induced Palmitate Synthesis in Overweight Subjects
Dietary fructose potently exacerbates the dyslipidemia associated with obesity, insulin resistance and accelerated atherosclerosis.
- Conditions
- Elevated Triglycerides, Diabetes, Cardiovascular Disease
- Trial name
- NCT00535535
- Testing
- Fructose, Fructose and Glucose
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Cholesterol, LDL
Effectiveness of Written Dietary Advice on Lipoproteins - a Pragmatic Randomized Controlled Trial
This study investigates the effect of detailed, written dietary advice for improving blood lipids, in a primary care setting. n=222 participants will be randomized to Active Intervention or Control Group.
- Trial name
- MYDICLIN (NCT03528252)
- Testing
- Written advice LDL Cholesterol, Written advice Triglycerides
- Where
- Sweden
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Nutritional and Metabolic Diseases, Lipemia
Effect of Muscle Damage After Downhill Running on Postprandial Lipids
All participants underwent three experimental trials, namely downhill running (DR), level running (LR), and the control (CON) in a cross-over design. Each trial lasted for 2 days.
- Trial name
- NCT04688073
- Testing
- Exercise, Rest
- Where
- Taiwan
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Cardiovascular Diseases, Cognition
Acute Impact of Whey Protein-enriched Milk Fat Globule Membrane Supplementation on Postprandial Markers of Heart and Brain Health
In a single-blind, randomised, placebo-controlled crossover manner, this study aims to assess the impact of a high-fat mixed meal containing a whey protein (WP)-enriched milk fat globule membrane (MFGM) powdered ingredient on…
- Conditions
- Cardiovascular Diseases, Cognition, Overweight or Obesity, Postmenopausal Women
- Trial name
- NCT06953232
- Testing
- Whey protein-enriched milk fat globule membrane supplement, Whey protein-based supplement
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Hypertriglyceridaemia
Understanding Liver Fat Metabolism: Studies to Understand the Role of Dietary Sugars on Liver Fat Metabolism
High levels of fatty substances in the blood increase the risk of developing coronary heart disease and having a heart attack. The investigators know a lot about one of these fatty substances, cholesterol.
- Trial name
- NCT02478541
- Testing
- Sugar study
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Lipid Metabolism, Glucose Metabolism
Digital Twin - Modelling Postprandial Triglyceride and Glucose Responses
Giving personalised dietary advice will help mitigate the postprandial increases in TG and glucose levels, and will assist in the battle against the increase in nutrition-related diseases, such as cardiovascular diseases.
- Trial name
- NCT05313594
- Testing
- Mixed meal challenge test, MRI, DEXA
- Where
- Netherlands
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Wageningen University and Research
Metabolic Syndrome
Metabolic Syndrome Cohort in Korea
Patients with metabolic syndrome living in Seoul area are included in this prospective registry for more than 10 years. All enrolled patients undergo thorough medical history survey.
- Trial name
- NCT02077530
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Healthy
Health Beneficial Effects of Krill Oil and Lean and Fatty Fish
Intake of omega-3 (n-3) polyunsaturated fatty acids (PUFAs) from fish oil and fish are associated with significant health benefits in risk of cardiovascular disease.
- Trial name
- NCT02568228
- Testing
- Krill oil, Lean and fatty fish
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Healthy
Investigation Of Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of Single Doses Of Vupanorsen In Japanese Healthy Adult Participants With Elevated Triglycerides
This is a Phase 1, randomized, double blind, third party open (i.e., participant blind, investigator blind and sponsor open), placebo controlled, single ascending dose study to investigate the safety, tolerability…
- Trial name
- NCT04459767
- Testing
- Vupanorsen
- Where
- Japan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Hypertriglyceridemias
Effects of Monascus Garlic Fermented Extract on Serum Triglyceride Level
The purpose of the study is to determine the effect of monascus garlic fermented extract on serum lipid concentrations in subjects with moderately elevated serum triglyceride.
- Trial name
- NCT00938249
- Testing
- Monascus Garlic Fermented Extract
- Where
- Japan
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Hiroshima University
Aging Skin, Body Mass Index
Clinical Profile of Skin Aging Based on Dermoscopy Photoaging Scale and Glogau Scale - Study of Leucocyte Telomere Length, Biomarker P16, and Body Mass Index
To determine the relationship between clinical appearance, dermoscopic examination results of photoaging profiles based on clinical examination, DPAS score and leucocyte telomere length, to analyze the relationship between BMI…
- Conditions
- Aging Skin, Body Mass Index, Cellular Senescence, Triglycerides
- Trial name
- LTLP16 (NCT06779032)
- Testing
- blood draw
- Where
- Indonesia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Bioavailability
Oxandrolone in Healthy Adults: A Relative Bioavailability Study
To assess the pharmacokinetics and relative bioavailability of a single dose of approximately 0.1 mg/kg of a medium chain triglyceride (MCT) oil oxandrolone solution vs. tablets in a small cohort of healthy adults.
- Trial name
- NCT03218631
- Testing
- Oxandrin
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Utah
Hypertriglyceridemia, Familial Hypercholesterolemia
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS ANGPTL3-LRx in Healthy Volunteers With Elevated Triglycerides and Participants With Familial Hypercholesterolemia
The purpose is to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of IONIS ANGPTL3-LRx (ISIS 703802) given to healthy volunteer subjects with elevated triglycerides and subjects with familial…
- Trial name
- NCT02709850
- Testing
- IONIS ANGPTL3-LRx
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ionis Pharmaceuticals, Inc.
Obesity
Study of Obesity Control by Astragalus and Notoginseng Extrats
The effects of the Astragalus and Notoginseng extrats on obesity control was demonstrated in a randomized double-blind, and crossover human trial.
- Trial name
- NCT03654391
- Testing
- InnoSlim
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Lipid Metabolism, Inborn Errors, Hyperlipidemias
Measure Liver Fat Content After ISIS 301012 (Mipomersen) Administration
This study will assess what, if any, effect that ISIS 301012 (mipomersen) has on liver triglyceride content in multiple groups of subjects with varying degrees of risk for hepatic steatosis.
- Conditions
- Lipid Metabolism, Inborn Errors, Hyperlipidemias, Metabolic Diseases, Hypolipoproteinemia
- Trial name
- NCT00362180
- Testing
- mipomersen
- Where
- Netherlands
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Kastle Therapeutics, LLC
Healthy
Multi-country Study- Effect of Dietary Fats on Fat Deposition
There is existing evidence to show that vegetable oils having unsaturated fatty acids in the sn-2 position with predominantly palmitic acid (C16:0) or stearic acid (C18:0) in the sn-1 and sn-3 positions of fat molecules do not…
- Trial name
- NCT02797483
- Testing
- Test Fat Blue, Test Fat Green, Test Fat Red
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
Metabolism
Effects of Fructose and Exercise on Hepatic Lipid Metabolism
8 healthy male volunteers will be studied each on 3 occasions, ie after 4 days on a weight maintenance diet containing 5% simple sugars + low physical activity after 4 days on a weight maintenance diet containing 30% fructose +…
- Trial name
- FRUCTEXER (NCT01121003)
- Testing
- weight maintenance, low sugar diet, weight maintenance, high fructose diet, weight maintenance, high fructose diet+ exercise
- Where
- Switzerland
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Lausanne