Clinical trials: Tubal Sterilization
Female Tubal Sterilization
Expedited Interval Tubal Scheduling
Over 50% of all pregnancies that occur in the US are unintended, and unintended pregnancy is detrimental to maternal and child health.
- Trial name
- ExITS (NCT02875483)
- Testing
- Expedited Scheduling, Standard Scheduling
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Sterilization, Tubal
Impact of Essure Tubal Sterilization Devices on the Endometrium
The mobilization of natural killer cells (uNK) triggers and coordinates all stages of embryo implantation. They are at the origin of the local secretion of cytokines, growth factors, chemokines affecting vascular development and…
- Trial name
- NCT01558882
- Testing
- Essure
- Where
- 4 sites in France
- Volunteers
- 2 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Tubal Sterilization
Characterization of the Essure System Tubal Sterilization Using Ultrasound and X-Ray
Tubal sterilization is the most prevalent form of contraception in the United States and the world. Currently, approximately half of these are performed with a laparoscope and half through a mini-laparotomy after delivery.
- Trial name
- NCT00588497
- Testing
- Micro-insert hysteroscopic sterilization, Plain abdominal Xray, Pelvic Ultrasound
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Mayo Clinic
Infertility
In Vitro Maturation With in Vitro Fertilization (IVF) Compared to Mild in Vitro Fertilization
Methods of infertility treatment may involve in vitro fertilization or IVF. Though effective, IVF is complex and expensive. Methods using no gonadotropin hormone stimulation of the ovaries are being compared to mild stimulation…
- Trial name
- IVM vs IVF (NCT00867763)
- Testing
- In vitro maturation and in vitro fertilization, Low doses of gonadotropin stimulation.
- Where
- 2 sites in United States
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- Batzofin Fertility Services
Contraception
FemBloc® Permanent Contraception - Early Pivotal Trial
Prospective, multi-center, international, non-randomized, two-arm study of subjects undergoing either FemBloc or laparoscopic bilateral tubal sterilization (Control).
- Trial name
- BLOC (NCT03433911)
- Testing
- FemBloc, Laparoscopic bilateral tubal sterilization
- Where
- 12 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Femasys Inc.
Contraception, Reproductive Behavior
Patient-centered Information on Permanent Contraception
The goal of this study is to understand whether providing information to women with a strong desire to avoid future pregnancy about how tubal sterilization compares to long-acting reversible contraceptives improves perceived…
- Conditions
- Contraception, Reproductive Behavior, Contraception Behavior
- Trial name
- NCT06296797
- Testing
- Control arm: Existing educational website, Advancing Access Website
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Tubal Sterilization, Women's Health
"My Decision" Tubal Sterilization Decision Support Tool
This study seeks to test a web-based decision support tool developed to enhance low-income women's ability to make informed decisions about tubal sterilization that align with their preferences, values and reproductive goals.
- Conditions
- Tubal Sterilization, Women's Health, Contraception, Contraception Behavior
- Trial name
- NCT04097717
- Testing
- "My Decision" tubal sterilization decision aid, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 549 people
- Sponsor
- University of Pittsburgh
Tubal Obstruction
Antispasmodic Drug for Diagnosis Proximal Tubal Occlusion on Hysterosalpingography
This study finds premedication Hyoscine-N-butylbromide before hysterosalpingography have a potential effect for diagnosis of proximal tubal obstruction in infertile women.
- Trial name
- NCT02618785
- Testing
- hysterosalpingography
- Where
- Thailand
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Sterilization Tubal, Salpingectomy
SALpingectomy for STERilization (SALSTER)
The SALSTER study is a register-based randomized clinical trial (R-RCT) that examines if laparoscopic salpingectomy instead of tubal ligation, as a contraceptive method, has no increased risk for complications and has no negative…
- Conditions
- Sterilization Tubal, Salpingectomy, Laparoscopy, Ovarian Reserve
- Trial name
- SALSTER (NCT03860805)
- Testing
- Laparoscopic tubal ligation, Laparoscopic bilateral salpingectomy
- Where
- Sweden
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Hydrosalpinx
Comparing the Impact of 2 Different Techniques in Management of Hydrosalpinx on Pregnancy Rates Following ICSI
Assessment and comparing pregnancy outcomes in hydrosalpinx patients treated by hysteroscopic tubal occlusion and laparoscopic salpingectomy before ICSI.
- Trial name
- NCT04335864
- Testing
- Laparoscopic salpingectomy, Hystroscopic proximal tubal occlusion
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Cairo University
Gynecologic Surgery
TUbal LIgation Per Differents Endoscopic Routes and Sexuality (TULIPES)
The goal of this clinical trial is compare the quality of sexual life at 6 months after tubal ligation, depending on whether it was performed by abdominal laparoscopy or by vNOTES, on the basis of a non-inferiority hypothesis.
- Trial name
- TULIPES (NCT05910385)
- Testing
- laparoscopy, vnotes
- Where
- 2 sites in France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hydrosalpinx, Infertility, Female
Hysteroscopic Tubal Occlusion Using Iso-Amyl 2-Cyano Acrylate (Amcrylate) in Patients With Hydrosalpinx
The purpose of this study is to assess the effectiveness of hysteroscopic tubal application of Iso Amyl-2-cyanoacrylate in occluding uterine tubes of infertile women with hydrosalpinx, which would make it an easy approach for…
- Trial name
- NCT02977234
- Testing
- Isoamyl 2-Cyanoacrylate
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hysterectomy
Proportion of Hysterectomy After Female Sterilization
The objective of this study is to describe the proportion of hysterectomy in patients that had undergone sterilization through hysteroscopic device placement and the patients that had undergone sterilization through tubal…
- Trial name
- NCT02532361
- Testing
- Hysteroscopic device placement including Essure (ESS305, BAY1454032), Tubal ligation
- Where
- United States
- Volunteers
- 10,578 people
- Sponsor
- Bayer
Female Infertility, Female Infertility Due to Ovulatory Disorder
Comparative Study on the Efficacy of Ovarian Stimulation Protocols on the Success Rate of ICSI in Female Infertility
The study will describe the effectiveness of ovarian stimulation in correlation with female infertility causes in a Lebanese population: a comparative study using 5 protocols of ovulation induction (treatment with "A"…
- Conditions
- Female Infertility, Female Infertility Due to Ovulatory Disorder, Premature Ovarian Failure, Polycystic Ovary Syndrome
- Trial name
- CS-EOSP-ICSI (NCT04071574)
- Testing
- Human Chorionic Gonadotropin (hCG), Gonadotropins, GNRH-A Triptorelin
- Where
- Lebanon
- Volunteers
- 200 people
- Sponsor
- Lebanese University
Contraception
Study to Assess Outcomes in Women Undergoing Either Hysteroscopic Sterilization (Essure®) or Laparoscopic Tubal Sterilization
This study is designed to assess post-procedural outcomes for women who chose to undergo either hysteroscopic sterilization (Essure®) or laparoscopic tubal sterilization, including: Pelvic and/or lower abdominal pain Abnormal…
- Trial name
- NCT03127722
- Testing
- Blood draw, ESSURE (BAY1454032), Laparoscopic tubal sterilization
- Where
- 57 sites in United States
- Volunteers
- 990 people, healthy volunteers welcome
- Sponsor
- Bayer
Pain
Pain Perception After Tubal Ligation
The purpose of this study is to attempt to determine retrospectively whether there was a statistically significant difference in patient need for postoperative narcotics between two different groups of women who received a…
- Trial name
- NCT01062087
- Testing
- Bupivacaine, Lidocaine
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University Center for Health Sciences
Contraception
Pilot Bi-Lateral Tubal Occlusion Trial for Female Permanent Contraception
Prospective, multi-center, pilot study evaluating the safety of the FemBloc® Permanent Contraceptive System for female sterilization in preventing pregnancy.
- Trial name
- BLOC (NCT03067272)
- Testing
- FemBloc® Permanent Contraceptive System
- Where
- 5 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Femasys Inc.
Sterilization, Tubal
Safety of Minilaparotomy Provided by Trained Clinical Officers and Assistant Medical Officers: a Non-inferiority Trial
The study is a non-inferiority randomized controlled trial (RCT) that aims to demonstrate that tubal ligations by minilaparotomy (ML) conducted by trained clinical officers (COs) are no less safe as compared to those conducted by…
- Trial name
- NCT02944149
- Testing
- tubal ligation by minilaparotomy
- Where
- 7 sites in Tanzania
- Volunteers
- 1,970 people, healthy volunteers welcome
- Sponsor
- EngenderHealth
Contraception
Opportunistic Salpingectomy for Permanent Sterilization at the Time of Cesarean Delivery
The purpose of this study is to compare the safety of performing a bilateral tubal ligation vs. bilateral salpingectomy, two procedures performed for permanent sterilization, at the time of cesarean delivery.
- Trial name
- NCT03135431
- Testing
- Bilateral Salpingectomy, Bilateral Tubal Ligation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Fallopian Tube Occlusion
Sonosalpingography After Hysteroscopic Tubal Occlusion
Sonosalpingography is done to assess the efficacy of hysteroscopic tubal occlusion by roller ball electrode.
- Trial name
- NCT03116867
- Testing
- sonosalpingography
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Ain Shams University