Clinical trials: Tubulointerstitial Kidney Diseases
Nephritis, Interstitial, Chronic Renal Failure
Hereditary Tubulointerstitial Nephritis
The aim of this study is to identify families with hereditary chronic tubulointerstitial renal diseases , characterize the phenotype and screen for mutations in known genesis (UMOD, REN, TCF2, NPHP1).
- Conditions
- Nephritis, Interstitial, Chronic Renal Failure, Gout, Renal Cysts
- Trial name
- NTIH (NCT01312727)
- Testing
- Blood and urine sample collections
- Where
- France
- Volunteers
- 225 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Kidney Disease, Diabetes Mellitus, Type 2
GLUcose Transport and REnalPROtection in Chronic Kidney Disease
This is a single-center, double blind, randomized, parallel-arms study designed to investigate the effects of a six-month treatment with the SGLT2i dapagliflozin on markers of kidney senescence, inflammation and…
- Conditions
- Chronic Kidney Disease, Diabetes Mellitus, Type 2, Hypertension
- Trial name
- GLUTREPRO (NCT05998837)
- Testing
- Dapagliflozin 10mg Tab
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
Kidney Diseases, Chronic, Glomerular Diseases
Model Development and Application Based on Renal Pathology Images
This single-center retrospective observational cohort study will utilize digital renal pathology images along with corresponding clinical and laboratory data from patients who underwent kidney biopsy at Union Hospital, Tongji…
- Conditions
- Kidney Diseases, Chronic, Glomerular Diseases, Tubulointerstitial Kidney Diseases, IgA Nephropathy (IgAN)
- Trial name
- NCT07816874
- Where
- China
- Volunteers
- 8,000 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Nephritis, Interstitial
Epidemiology, Diagnosis, Medical Care and Prognosis of Tubulointerstitial Nephritis: Results of a Multicenter Retrospective Cohort Study
Tubulointerstitial nephritis (TIN), diagnosed on kidney biopsy, represents a common cause of kidney failure. The etiologies are multiple but the diagnosis of the causative disease is sometimes difficult and the treatment is not…
- Trial name
- NETI-MULTI (NCT06650111)
- Testing
- Rereading of biopsies, Collection of data from the patient's medical file
- Where
- 3 sites in France
- Volunteers
- 224 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Interstitial Nephritis
Xolair (Omalizumab) for Treatment of Drug-induced Acute Tubulointerstitial Nephritis (AIN)
The investigators goal is to evaluate the role of XOLAIR® in treatment of Acute Tubulointerstitial Nephritis (AIN) with the goal of shortening the duration and dose of prednisone for treatment of drug-induced AIN.
- Trial name
- NCT01893658
- Testing
- Omalizumab, Prednisone
- Where
- United States
- Sponsor
- Mayo Clinic
Nephropathy, Chronic Tubulointerstitial
Self-administered Questionnaire to Evaluate Salt and Potassium Diet of Patients Followed in Nephrology
The aim of the study is to create a self-questionnaire to evaluate sodium and potassium diet in chronic kidney disease patients.
- Trial name
- UniverSEL (NCT04195802)
- Testing
- Salt and potassium Diet
- Where
- France
- Volunteers
- 542 people
- Sponsor
- Hospices Civils de Lyon
Acute Kidney Injury, Acute Interstitial Nephritis
Biorepository to Support Research in Kidney Diseases
To support advances in the understanding of pathophysiology and therapies of kidney diseases by creating a BioBank of kidney tissue, DNA, plasma, and urine from patients with kidney diseases.
- Conditions
- Acute Kidney Injury, Acute Interstitial Nephritis, Kidney Diseases
- Trial name
- NCT04343417
- Where
- 2 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Yale University
Glomerular Disease
Pathogenesis of Glomerulosclerosis
The present protocol seeks to advance our understanding of sclerosing glomerular and tubulointerstitial kidney diseases, including but not limited to variants of focal segmental glomerulosclerosis (FSGS) and chronic kidney…
- Trial name
- NCT00001392
- Where
- United States
- Volunteers
- 537 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Acute Kidney Injury, Acute Interstitial Nephritis
Infliximab for Immune Checkpoint Inhibitor Associated AKI
This is a multi-center, 1:1 randomized pilot study examining the efficacy and safety of infliximab 5mg/kg x 1 paired with 2 weeks of prednisone 1mg/kg per day for 2 weeks versus standard-of-care glucocorticoid therapy (prednisone…
- Trial name
- NCT07683975
- Testing
- Infliximab, Prednisone, prednisone (oral)
- Where
- 3 sites in United States
- Volunteers
- 44 people
- Sponsor
- Massachusetts General Hospital
Chronic Allograft Nephropathy
Validity of Strain Elastography for the Evaluation of Chronic Allograft Nephropathy
Chronic allograft nephropathy is one of dreaded complication of kidney transplant. It is one of the major determinants of long term graft survival.
- Trial name
- NCT05682313
- Testing
- Elastography arm
- Where
- Egypt
- Volunteers
- 188 people
- Sponsor
- Kasr El Aini Hospital