Clinical trials: Tumor Burden
Nurse-led Supportive Care
Effects of Nurse-led Supportive Care Programme on Caregiver Burden and Resilience of Family Caregivers
Lung cancer is the leading cause of cancer-related deaths worldwide, with a mortality rate of 18%. The prognosis of lung cancer is progressive and devastating, which may cause patients to experience problems during the treatment…
- Trial name
- NCT06204289
- Testing
- Nurse-led Supportive Care Programme
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Izmir Bakircay University
Healthy Volunteers, Cancer Patients
Clinical Study of 18F-LNC1007 Injection PET/CT
This study is a single-arm, single-center trial aimed at evaluating the pharmacokinetics, bio-distribution, dosimetry, and safety of 18F-LNC1007 injection in healthy volunteers and light tumor burden cancer patients, as defined…
- Trial name
- NCT06471712
- Testing
- 18F-LNC1007 Injection
- Where
- Australia
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Yantai LNC Biotechnology Singapore PTE. LTD.
Renal Cell Carcinoma
Disease Burden and Biology Using Tumor Cell Free DNA in Metastatic Kidney Cancer
This study will assess whether DNA released by kidney cancer into the blood stream and urine of patients can be used to monitor tumor burden and tumor response to treatment in patients receiving immunotherapy
- Trial name
- NCT04883827
- Testing
- Blood collection, Urine collection
- Where
- 3 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Malignant Glioma, Anxiety
Psychological Intervention For Brain Tumor Caregivers
This study is testing a supportive psychosocial intervention for caregivers of people who have malignant brain tumors such as gliomas or other high-grade primary brain tumors.
- Conditions
- Malignant Glioma, Anxiety, Caregiver Burden, Malignant Brain Tumor
- Trial name
- NCT04109209
- Testing
- Psychosocial Intervention Group, Usual Care Group
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Advanced Malignant Neoplasm, Locally Advanced Malignant Neoplasm
Caregiver Burden, Quality of Life, and Symptom Distress at Different Palliative Cancer Care Settings
This trial studies caregiver burden, quality of life, and symptom distress of patients and their informal (unpaid) caregivers at different palliative care settings.
- Conditions
- Advanced Malignant Neoplasm, Locally Advanced Malignant Neoplasm, Metastatic Malignant Neoplasm, Recurrent Malignant Neoplasm
- Trial name
- NCT04186884
- Testing
- Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Burnout, Caregiver, Compassion Fatigue
Exercise for Oncology Care Professionals
The goal of this preference-based pilot study will be to assess the feasibility and acceptability, and impact of a 12-week exercise intervention on oncology care provider burnout.
- Trial name
- C4C+ (NCT05884073)
- Testing
- Circuit-based Resistance Training, Nature-based Walking
- Where
- 2 sites in Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Melanie Keats
Depression, Anxiety
The Mental Health Experiences of Sexual and Gender Minorities Living With Cancer and Their Care Partners
The purpose of this study is to examine relationships between contextual stressors and stress moderators, depression symptom experience, resilience, frailty, and quality of life among older sexual gender minorities cancer…
- Conditions
- Depression, Anxiety, Caregiver Burden, Stress
- Trial name
- SGMC (NCT05866705)
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Caregiver Burden, Bereavement
Caregiver Stress and Bereavement
The death of a spouse is considered one of the most stressful and impactful life events and is associated with increased morbidity and premature mortality.
- Conditions
- Caregiver Burden, Bereavement, Cancer
- Trial name
- NCT05867706
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Caregiver Burden
Combined Effects of mHealth Psychoeducational and Benson Relaxation Technique Among Female Informal Caregivers of Cancer Patients in Bangladesh
Background: Cancer is a global health concern that places a substantial burden not only on patients but also on their informal caregivers, often family members or close friends without formal medical training.
- Trial name
- NCT06204328
- Testing
- Benson relaxation technique and mHealth psychoeducation
- Where
- Bangladesh
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Hiroshima University
Malignant Brain Tumors
PRESENCE Project: An Early Palliative Care Intervention in Brain Tumors
The purpose of this pilot study is to investigate the feasibility of an early palliative care intervention (PRESENCE: Providing Resources Education, Support, and Enabling New brain tumor patients to Cope Effectively) and the…
- Trial name
- NCT01652768
- Testing
- Research Questionnaires, Palliative Care Team, Educational Information Session for Patients and Caregivers
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Multiple Myeloma, Caregiver Subjective Burden
The Burden of Multiple Myeloma on Patients and Caregivers Quality of Life: a Canadian Real-World Study
The purpose of this observational study is to estimate the burden of multiple myeloma on patients and caregivers in terms of QoL.
- Conditions
- Multiple Myeloma, Caregiver Subjective Burden, Quality of Life (QOL)
- Trial name
- NCT06610045
- Testing
- No intervention
- Where
- Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- PeriPharm
Caregiver Burnout, Cancer
The Effect of Progressive Relaxation Exercise on Caregiver Burden, Fatigue and Quality of Life in Caregivers of Patients With Advanced Cancer: Randomized Controlled Clinical Study
Caregivers of patients with advanced cancer will be entered. Participants will be randomized to one of two study arms: Arm 1: Progressive muscle relaxation; Arm 2: Attention matched control.
- Trial name
- NCT04292678
- Testing
- Progressive muscle relaxation, Attention matched control
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Anal Cancer, Human Papilloma Virus
Anal Cancer Risk In Women
This is a retrospective cross-sectional study involving the analysis of Cancer Registry Data. As part of this study, cancer registration data collated by the National Cancer Registration and Analysis Service (NCRAS; the national…
- Conditions
- Anal Cancer, Human Papilloma Virus, Anal Intraepithelial Neoplasia, Genital Neoplasm
- Trial name
- NCT05835947
- Testing
- Dual Pathology
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Neoplams, Prostate Cancer (Adenocarcinoma)
Pilot Feasibility Study of a Dyadic Culinary Nutrition Intervention
This study will determine the feasibility and acceptability of a 12-week dyadic culinary nutrition program among Hispanic prostate cancer survivor/caregiver dyads using a randomized controlled trial design.
- Conditions
- Neoplams, Prostate Cancer (Adenocarcinoma), Cancer Survivors, Caregiver Burden
- Trial name
- CHEF (NCT07702864)
- Testing
- Cooking Healthy - Engaging Families (CHEF), Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Trauma and Stressor Related Disorders, Pediatric Cancer
Emotion and Symptom-Focused Engagement (EASE) for Caregivers
The goal of this Phase III randomized controlled trial is to evaluate the effectiveness of a novel psychotherapeutic intervention called Emotion and Symptom-focused Engagement (EASE) in parents caring for a child or adolescent…
- Conditions
- Trauma and Stressor Related Disorders, Pediatric Cancer, Caregiver Burden
- Trial name
- EASE (NCT06367556)
- Testing
- Emotion and Symptom-Focused Engagement (EASE)
- Where
- 2 sites in Canada
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Glioblastoma
Easing Psychosocial Burden for Informal Caregivers
The overall goal of this study is to determine the best time to offer Meaning-Centered Psychotherapy (MCP), an intervention that has proven to be helpful in improving spiritual well-being and decreasing existential distress among…
- Trial name
- NCT03454295
- Testing
- Focus Group, Meaning-Centered Psychotherapy for Cancer Caregivers / MCP-C, Enhanced Usual Care / EUC
- Where
- 3 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Non-small Cell Lung Cancer
A Prospective Study of Constructing Immune Repertoire to Monitor the Therapeutic Effect in NSCLC Patients
This study is designed to evaluate the untreated NSCLC patients. After participants have accepted chemotherapy, radiotherapy, and immunotherapy, the investigators used the next generation sequence technology (NGS) to construct…
- Trial name
- NCT03373955
- Testing
- pembrolizumab
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sichuan University
Dementia, Dysphagia
Family Caregiver Online Survey (Dementia and Swallowing Difficulties)
The Family Caregiver Survey is a one-time, 30-minute, online survey for people living with and caring for a family member with dementia.
- Conditions
- Dementia, Dysphagia, Dementia Alzheimers, Dementia, Vascular
- Trial name
- NCT06471660
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Breast Cancer
Managing Breast Cancer Treatment: Dyad's Perspectives on Treatment Decision, Financial and Family Burden.
The purpose of this study is to understand the financial burden and treatment decisions, based on both of patient's and family's perspectives in breast cancer patients who receive systemic chemotherapy, targeted therapy or…
- Trial name
- NCT05917444
- Where
- Taiwan
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Leukemia
Symptom Burden in Chronic Myeloid Leukemia (CML)
Objectives: The objective of this study is to measure and delineate the symptom burden experienced by patients with chronic myeloid leukemia (CML). The Primary Aim is to develop and validate an M. D.
- Trial name
- NCT01046305
- Testing
- Interview & Questionnaires, Rating Questionnaire, MDASI-CML Questionnaire
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center