Clinical trials: Tumor Gastric
Gastric Cancer
Pemetrexed Plus Cisplatin as First-Line Treatment in Stage IV or Recurrence of Gastric Cancer
Study H3E-MW- S108 is a multicenter, single arm, open-label Phase 2 study to determine the response rate of pemetrexed plus cisplatin in patients with Stage IV gastric cancer, not amenable to curative surgery, or recurrence after…
- Trial name
- NCT00415168
- Testing
- pemetrexed, cisplatin
- Where
- 6 sites in Russia
- Volunteers
- 53 people
- Sponsor
- Eli Lilly and Company
Pancreatic Tumor, Gastric Tumor
Comparing the Efficacy of Endoscopic FNA vs FNB in Diagnosing Solid Gastrointestinal Lesions
The purpose of this study is to determine if fine needle aspiration or fine needle biopsy is more efficacious and cost-effective than the other while maintaining diagnostic accuracy in the setting of solid gastrointestinal…
- Conditions
- Pancreatic Tumor, Gastric Tumor, Esophageal Tumor, Lymphadenopathy
- Trial name
- NCT01698190
- Testing
- Endoscopic ultrasound guided needle tissue acquisition.
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Stony Brook University
Colorectal Cancer, Gastric Cancer (GC)
Topical Diclofenac for Hand-Foot Syndrome Prevention in Colorectal and Gastric Cancer on Capecitabine (DICLO-HFS)
Hand-foot syndrome (HFS) is a frequent adverse effect of capecitabine, presenting with redness, swelling, pain, and peeling of the skin on the palms and soles.
- Conditions
- Colorectal Cancer, Gastric Cancer (GC), Capecitabine, Hand Foot Syndrome
- Trial name
- DICLO-HFS (NCT07177560)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 151 people
- Sponsor
- Gazi University
Recurrent Ovarian Cancer, HER2-negative
HS-10502 Combination Treatment in Patients With Advanced Solid Tumors
HS-10502 is a PARP1-specific selective inhibitor. The purpose if this study is to assess the safety, tolerability, pharmacokinetics (PK), and efficacy of HS-10502 Combination Treatment in subjects with advanced solid tumors.
- Conditions
- Recurrent Ovarian Cancer, HER2-negative, Advanced Breast Cancer, TNBC
- Trial name
- HS-10502 (NCT06769425)
- Testing
- HS-10502 + NHA, HS-10502 + HS-20093, HS-10502+ Apatinib
- Where
- China
- Volunteers
- 157 people
- Sponsor
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
Gastric Cancer
Evaluate the Efficacy of Maintenance Treatment With Capecitabine Plus Apatinib in Advanced Gastric Cancer
This is a multicenter, randomized, controlled trial to evaluate the efficacy and safety of Maintenance Treatment with Capecitabine plus Apatinib, Apatinib and Observation after First-line XELOX/SOX chemotherapy for Patients with…
- Trial name
- NCT03598348
- Testing
- Apatinib+Capecitabine, Apatinib
- Where
- China
- Volunteers
- 288 people
- Sponsor
- Huazhong University of Science and Technology
Gastric Adenocarcinoma, Stage II Gastric Cancer
Irinotecan and Cisplatin in Treating Patients Who Are Undergoing Surgery For Locally Advanced Cancer of the Stomach or Gastroesophageal Junction
This phase II trial is studying how well giving irinotecan together with cisplatin works in treating patients who are undergoing surgical resection for locally advanced cancer of the stomach or gastroesophageal junction.
- Conditions
- Gastric Adenocarcinoma, Stage II Gastric Cancer, Stage III Gastric Cancer, Stage IV Gastric Cancer
- Trial name
- NCT00062374
- Testing
- Cisplatin, Computed Tomography, Fludeoxyglucose F-18
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- National Cancer Institute (NCI)
Gastric Carcinoma
The Clinical Significance of Examining Metastatic Lymph Nodes in Individual Gastric Mesenteries in the Patients With Gastric Cancer Undergoing Gastrectomy
This study aims to examine the predictive value of metastatic gastric mesenteries, which contains metastatic lymph node, in 6 gastric mesenteries; and importantly, to further evaluate the relationship between the number of…
- Trial name
- NCT07139418
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Jichao Qin
Gastric Cancer
Efficacy and Safety of Perioperative Chemotherapy Plus PD-1 Antibody in Gastric Cancer
For locally advanced gastric cance, neoadjuvant chemotherapy can increase the resectability of tumor, and finally improve the long-term survival.
- Trial name
- NCT04367025
- Testing
- Camrelizumab, Oxaliplatin, S1
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Chinese PLA General Hospital
Gastric Cancer
Neoadjuvant Adebrelimab + DOS in Locally Advanced Resectable Gastric Cancer
To evaluate the efficacy and safety of adebrelimab combined DOS in neoadjuvant treatment of locally advanced resectable gastric cancer.
- Trial name
- NCT06475417
- Testing
- Adebrelimab combined with DOS
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Tang-Du Hospital
Gastric Adenocarcinoma
Dose-dense Biweekly Docetaxel Combined With 5-fluorouracil as First-line Treatment in Advanced Gastric Cancer
This is an open-label, phase II study to evaluate the efficacy and safety of biweekly docetaxel and DeGramont regimen on unresectable gastric adenocarcinoma in the first-line therapy.
- Trial name
- DaeMon (NCT01567618)
- Testing
- Docetaxel, Fluorouracil
- Where
- China
- Volunteers
- 39 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Melanoma, Non Small Cell Lung Cancer
Safety, PK and Efficacy of AI-061 in Advanced Solid Tumors
AI-061 is a co-formulation drug product (DP) consisting of 1:1 ratio mix of AI-025, an anti-PD-1 antibody, and ONC-392, an anti-CTLA-4 antibody.
- Conditions
- Melanoma, Non Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma, High Grade Serous Adenocarcinoma of Ovary
- Trial name
- PRESERVE-009 (NCT05858736)
- Testing
- AI-061
- Where
- 5 sites in Australia
- Volunteers
- 18 people
- Sponsor
- OncoC4, Inc.
Gastric Cancer, Duodenal Stump Leak
Incidence of Duodenal Stump Fistula After Gastrectomy for Gastric Cancer. A Randomized Controlled Trial
The goal of this trial is to demonstrate that the use of Tri-Staple Technology for duodenal resection during open gastrectomy for cancer is safer than the use of other conventional methods of resection/closure of the duodenum and…
- Trial name
- DRTST (NCT03277144)
- Testing
- TST-TriStaple(3lines stapler)Technology, other conventional techniques
- Where
- Italy
- Volunteers
- 700 people
- Sponsor
- University of Turin, Italy
Endoscopic Submucosal Dissection, Gastric Neoplasm
Learning Curve for Gastric Endoscopic Submucosal Dissection
Endoscopic submucosal dissection (ESD) for early gastric cancer is a widely accepted treatment option of expanded indication worldwide.
- Trial name
- NCT05265221
- Testing
- Endoscopic submucosal dissection
- Where
- South Korea
- Volunteers
- 356 people
- Sponsor
- Soonchunhyang University Hospital
Stomach Neoplasms
Multi-center and Multi-modal Deep Learning Study of Gastric Cancer
To assist postoperative pathological diagnosis and classification of gastric cancer by machine learning; To improve the accuracy of pathological diagnosis of gastric cancer by machine learning; To predict the effectiveness of…
- Trial name
- NCT05001321
- Testing
- The whole abdomen contrast-enhanced CT scan, H&E stained sections and slides
- Where
- 6 sites in China
- Volunteers
- 3,300 people
- Sponsor
- First Hospital of China Medical University
Esophageal Cancer, Gastric Cancer
Prospective Analysis of Robot-Assisted Surgery
The robot-assisted surgery allows three-dimensional view, detailed access of small structures, depth perception and articulated movements with wide latitude.
- Conditions
- Esophageal Cancer, Gastric Cancer, Pancreatic Cancer, Rectal Cancer
- Trial name
- NCT02292914
- Testing
- Robot-assisted surgery, Conventional Surgery
- Where
- Brazil
- Volunteers
- 1,120 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Gastric (Cardia, Body) Cancer, Stomach Adenocarcinoma
Neoadjuvant Nab-Paclitaxel Plus Oxaliplatin, S-1, and Sintilimab in Early-Onset Resectable Gastric Cancer
This study aims to evaluate the effectiveness and safety of a preoperative treatment (called neoadjuvant therapy) combining four drugs-nab-paclitaxel, oxaliplatin, S-1, and sintilimab-for patients with locally advanced…
- Conditions
- Gastric (Cardia, Body) Cancer, Stomach Adenocarcinoma, Locally Advanced
- Trial name
- YOUNG-NEOS (NCT07018063)
- Testing
- nab-paclitaxel, oxaliplatin, S-1
- Where
- China
- Volunteers
- 35 people
- Sponsor
- zhoujing
Gastric Cancer, Hepatocellular Carcinoma
Phase II Study of PRL3-ZUMAB in Advanced Solid Tumors
This is a Phase II, open-label, single dose level study of PRL3-ZUMAB monotherapy in patients with advanced solid tumours that have failed standard therapy.
- Conditions
- Gastric Cancer, Hepatocellular Carcinoma, Advanced Solid Tumor
- Trial name
- NCT04118114
- Testing
- PRL3-zumab
- Where
- Singapore
- Volunteers
- 14 people
- Sponsor
- National Cancer Centre, Singapore
B-ALL, DLBCL
Iomab-ACT: A Pilot Study of 131-I Apamistamab Followed by CD19-Targeted CAR T-Cell Therapy for Patients With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia or Diffuse Large B-Cell Lymphoma
This is a pilot study; patients will receive 131-I apamistamab prior to CAR T-cell infusion in order to determine the maximum tolerated dose of 131-I apamistamab is exceeded at 75 mCi, and if so, to assess the safety of a…
- Conditions
- B-ALL, DLBCL, B ALL, Dlbcl-Ci
- Trial name
- NCT04512716
- Testing
- 131-I Apamistamab, CAR T-cell
- Where
- 7 sites in United States
- Volunteers
- 12 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Gastric Cancer
Adjuvant Capecitabine Versus Observation Alone in Curatively Resected Stage IB Gastric Cancer((KCSG ST14-05): CATALYSIS
multi-center, prospective, randomized, open-label phase III
- Trial name
- NCT01917552
- Testing
- capecitabine
- Where
- South Korea
- Volunteers
- 870 people
- Sponsor
- Asan Medical Center
Gastric Cancer, Esophageal Cancer
Development of a Clinical Decision Support System With Artificial Intelligence for Cancer Care
Clinical Decision Support Systems (CDSSs) to augment clinical care and decision making. These are platforms which aim to improve healthcare delivery by enhancing medical decisions with targeted clinical knowledge, patient…
- Conditions
- Gastric Cancer, Esophageal Cancer, Esophagogastric Junction Cancer
- Trial name
- NCT04675138
- Testing
- No intervention will be provided to the subject
- Where
- 9 sites in Germany, Japan and 4 more
- Volunteers
- 1,000 people
- Sponsor
- National University Hospital, Singapore
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