Clinical trials: Tumor Gastric
Stomach Neoplasms, Rectal Neoplasms
Study of the Efficacy and Safety of Epoetin Alfa Administered Weekly in Patients With Gastric or Rectal Cancers Undergoing a Treatment Plan of Preoperative Chemotherapy and Radiation Therapy, Followed by Surgery
The purpose of this study is to evaluate the effectiveness and safety of epoetin alfa on the reduction in red blood cell transfusions needed in gastric cancer patients and rectal cancer patients undergoing a treatment plan of…
- Trial name
- NCT00036400
- Testing
- epoetin alfa
- Volunteers
- 60 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Esophageal Cancer, Gastric Cancer
Octreotide Treatment to Improve Nutritional Recovery After Surgery for Patients with Esophageal or Gastric Cancer
The aim of the study is to clarify whether octreotide therapy can reduce undesired postoperative weight loss, increase health-related quality of life and improve the appetite after surgery for esophageal or gastric cancer.
- Trial name
- OTIS (NCT04871204)
- Testing
- Octreotide Injection
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Fredrik Klevebro
Gastric Cancer, Lung Cancer
Evaluation of Respiratory Motion-Corrected Cone-Beam CT in Radiation Treatment of Thoracic and Abdominal Cancers
Tumors must be seen clearly on CT scan to be radiated completely and safely. Breathing causes tumors to move. If the tumor moves during breathing, it can look blurred on the CT scan. This makes it difficult to see on CT scan.
- Trial name
- NCT01213004
- Testing
- respiration correlated CT scan
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Gastric Cancer, Gastro Esophageal Junction Cancer
Perioperative Surufatinib Plus Sintilimab Combined With Chemotherapy in Gastric/Gastroesophageal Junction Adenocarcinoma
For locally advanced gastric and gastroesophageal junction adenocarcinoma (cT3-4bNanyM0), perioperative PD-1 antibody combined with chemotherapy can downstage tumor stage, increase the R0 resection rate, and may improve the…
- Trial name
- NCT06447636
- Testing
- Surufatinib, Sintilimab, Oxaliplatin
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Fudan University
Gastric Cancer
Phase II Study of TS-1 Therapy and TS-1+PSK Therapy Against Advanced Gastric Carcinoma
A randomized controlled study is conducted on unresectable advanced gastric carcinoma and recurrent gastric carcinoma to compare TS-1 therapy with TS-1 + PSK therapy.
- Trial name
- eNCIT-Japan (NCT00503321)
- Testing
- Tegafur/gimeracil/oteracil potassium (S-1), Krestin (PSK), Tegafur/gimeracil/oteracil potassium (S-1)
- Where
- Japan
- Volunteers
- 13 people
- Sponsor
- Eastern Network of Cancer Immunological Therapy, Japan
Gastric Cancers
R-GASTIM- Study of Gastric Cancer Operable
Clinicobiological cohort of gastric cancers operated in our institution.
- Trial name
- R-GASTIM (NCT07787052)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Leon Berard
Gastric Cancer
Validating the Safety and Effectiveness of ENDOANGEL Upper Gastrointestinal Endoscope Image Auxiliary Diagnostic Software
The upper Gastrointestinal Endoscope Image Auxiliary Diagnostic Software developed by Wuhan ENDOANGEL Medical Technology Co., Ltd.
- Trial name
- NCT05470452
- Testing
- The reading process is assisted by ENDOANGEL, No ENDOANGEL assistance during the reading process
- Where
- China
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Hepatocellular Carcinoma (HCC), Gastro-Entero-Pancreatic Tumors (GEPs)
Evaluating the roLe of Multiplexed PET Imaging in the Detection and Staging of hepatocellulaR Carcinoma and gAstro-entero-pancreatic Tumors
Precision medicine is a major goal in oncology. It aims to tailor treatments to the specific characteristics of each patient's tumor.
- Trial name
- ELMIRA (NCT07178587)
- Testing
- Single tracer PET/CT, Multiplexed PET-CT
- Where
- 3 sites in France
- Volunteers
- 28 people
- Sponsor
- Nantes University Hospital
Gastric Cancer
Dynamic Circulating Tumor DNA Monitoring to Guide Systemic Therapy in Gastric Cancer
This study aims to evaluate the clinical value of circulating tumor DNA (ctDNA) as a minimally invasive biomarker for monitoring treatment response and guiding systemic therapy in patients with gastric or gastroesophageal…
- Trial name
- NCT07517107
- Testing
- Circulating Tumor DNA (ctDNA) Analysis, Standard Systemic Therapy for Gastric Cancer
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Fudan University
Gastric Cancers
Correlation of Psychological Distress and Immune Checkpoint Inhibitors in Gastric Cancer
1. Background Gastric cancer (GC) is a leading global cause of cancer-related mortality, with over 1 million new cases and 769,000 deaths in 2020.
- Trial name
- PDICI (NCT07003334)
- Where
- China
- Volunteers
- 268 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Stomach Neoplasms, Gastric Cancer
Neoadjuvant Immunotherapy Plus Chemotherapy in Borrmann Type 4 and Large Type 3 Gastric Cancer
The aim of this study is to test the efficacy and safety of immunotherapy plus chemotherapy on people with a relatively rare type of gastric cancer.
- Conditions
- Stomach Neoplasms, Gastric Cancer, Linitis Plastica of Stomach
- Trial name
- Neo-ICEBOAT (NCT06451211)
- Testing
- Tislelizumab, Oxaliplatin, S-1
- Where
- China
- Volunteers
- 53 people
- Sponsor
- Sun Yat-sen University
HER2-positive Gastric Cancer
Cinrebafusp Alfa in Combination With Ramucirumab and Paclitaxel in HER2-High Gastric or GEJ Adenocarcinoma and in Combination With Tucatinib in HER2-Low Gastric or GEJ Andenocarinoma
A Phase 2, multi-center, open-label study of cinrebafusp alfa (PRS-343) in combination with ramucirumab and paclitaxel in patients with HER2-high and in combination with tucatanib in patients with HER2-low gastric or…
- Trial name
- NCT05190445
- Testing
- Cinrebafusp alfa (PRS-343) in combination with ramucirumab and paclitaxel, Cinrebafusp alfa (PRS-343) in combination with tucatinib
- Where
- 5 sites in United States, South Korea
- Volunteers
- 80 people
- Sponsor
- Pieris Pharmaceuticals, Inc.
Liver Metastases, Gastric Adenocarcinoma
CT Radiomics and Deep Learning-Based Non-Invasive Model for Tracing Primary Sites of Adenocarcinoma Liver Metastases: Automatic Differentiation of Multiple Primary Digestive Tumors
This is a retrospective observational study. Liver metastasis occurs frequently in digestive-system cancers. Identification of the primary tumor source of liver metastasis may pose clinical challenges.
- Conditions
- Liver Metastases, Gastric Adenocarcinoma, Colorectal Adenocarcinoma, Biliary Tract Adenocarcinoma
- Trial name
- NCT07871019
- Testing
- Retrospective image analysis
- Where
- China
- Volunteers
- 700 people
- Sponsor
- West China Hospital
Peritoneal Metastases, Gastric Cancer
HIPEC Combined With SOX and Sintilimab in the Treatment of Advanced Gastric Cancer With Peritoneal Metastasis
The prognosis of patients with peritoneal metastasis from gastric cancer is extremely poor. Although chemotherapy combined with immunotherapy has achieved promising efficacy in the first-line treatment of advanced gastric cancer…
- Trial name
- NCT06213519
- Testing
- S-1, Oxaliplatin sintilimab HIPEC
- Volunteers
- 69 people
- Sponsor
- Sichuan University
Stomach Neoplasm
Laparoscopic vs. Open Distal Gastrectomy After Neoadjuvant Chemotherapy
The study was designed as single-country, multi-center, open-labelled, randomized (1:1), phase II trial. 238 patients with medically and technically operable advanced gastric adenocarcinoma in middle or distal 1/3 of stomach are…
- Trial name
- NCT04658589
- Testing
- Laparoscopic versus open distal gastrectomy
- Volunteers
- 238 people
- Sponsor
- Chonnam National University Hospital
Advanced Gastric Cancer
Evaluation of Pressurized Intraperitoneal Aerosol Chemotherapy With VRT106 Versus PIPAC in Patients With Advanced Gastric Cancer and PeritonealMetastasis: A Prospective, Multicenter, Open-Label, Randomized Controlled Trial
This study is a prospective, multicenter, open-label, randomized controlled clinical trial, planned to enroll 30 patients with advanced gastric cancer and peritoneal metastasis.
- Trial name
- NCT07486310
- Testing
- Doxorubicin (Adriamycin), VRT106
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Guangdong Provincial People's Hospital
Esophageal Adenocarcinoma (UICC TNM7), Adenocarcinoma of the Esophagogastric Junction
Perioperative Chemotherapy Compared To Neoadjuvant Chemoradiation in Patients With Adenocarcinoma of the Esophagus
The trial is designed to investigate differences in outcome of patients with esophageal adenocarcinoma and junctional adenocarcinoma treated with perioperative (neoadjuvant + adjuvant) chemotherapy (FLOT) plus surgical resection…
- Trial name
- ESOPEC (NCT02509286)
- Testing
- 5-Fluorouracil, Leucovorin, Oxaliplatin
- Where
- 30 sites in Germany
- Volunteers
- 438 people
- Sponsor
- University Hospital Schleswig-Holstein
Gastrostomy
Predictive Factors for Roux Stasis Syndrome
Patients who were pathologically diagnosed with gastric cancer and underwent distal gastrectomy with R-Y reconstruction between March 2014 and March 2021 were retrospectively analyzed.
- Trial name
- PFRSS (NCT04919577)
- Testing
- X-ray
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Peking University Third Hospital
Gastric Cancer
Phase I/II Study of Paclitaxel Plus CPT-11 in Pts. With 2nd Line Chemotherapy of Inoperable or Recurrent GC.
A phase I/II study is conducted to determine the maximum-tolerated dose (MTD), dose-limiting toxicity (DLT), and efficacy of a combination chemotherapy using CPT-11 and Paclitaxel in pre-treated patients with metastatic gastric…
- Trial name
- NCT00209612
- Testing
- Taxol, Campt, Topotesin
- Where
- Japan
- Volunteers
- 40 people
- Sponsor
- Hokkaido Gastrointestinal Cancer Study Group
Gastric Cancer
Comparison Partial Versus Total Omentectomy in Minimal Invasive Distal Gastrectomy for cT3/4a Gastric Cancer (KLASS-10)
For advanced gastric cancer, surgical resection is the only curable therapeutic strategy. According to minimally invasive approach is adopted in various field of oncologic surgery, laparoscopic gastrectomy with lymph node…
- Trial name
- NCT06608381
- Testing
- Arm I (Total omentectomy),, Arm II (Partial omentectomy)
- Where
- South Korea
- Volunteers
- 440 people
- Sponsor
- Gangnam Severance Hospital
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