Clinical trials: Type 2 Diabetes, completed
Diabetes, Diabetes Mellitus, Type 1
Pharmacokinetics of Biphasic Insulin Aspart 30 and 70 in Subjects With Type 1 Diabetes
This trial is conducted in Europe. The aim of this trial is to investigate steady state pharmacokinetics of biphasic insulin aspart 30 and biphasic insulin aspart 70 in subjects with type 1 diabetes.
- Trial name
- NCT01524809
- Testing
- biphasic insulin aspart 30, biphasic insulin aspart 70
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes
Safety and Pharmacokinetics Study of XOMA 052 in Subjects With Type 2 Diabetes Mellitus
The purpose of this study is to evaluate the safety and pharmacokinetics (PK) of XOMA 052 in subjects with stable Type 2 Diabetes Mellitus (T2D).
- Trial name
- NCT00513214
- Testing
- XOMA 052
- Where
- 4 sites in United States
- Volunteers
- 68 people
- Sponsor
- XOMA (US) LLC
Diabetes Type 2, NAFLD
Effects of a Portfolio Diet on NAFLD in Type 2 Diabetic Patients
Patients with type 2 diabetes and non-alcoholic fatty liver disease will be enrolled. According to a parallel design, the participants will be randomized to a Portfolio diet or a monounsaturated fatty acid (MUFA)-rich diet (used…
- Trial name
- MEDEA (NCT03380416)
- Testing
- Portfolio Diet, MUFA Diet
- Where
- Italy
- Volunteers
- 49 people
- Sponsor
- Federico II University
Hypertension, Diabetes Mellitus, Type 2
ENCOMPASS: Expansion Study A, RCT
Some patients living with multiple long-term health conditions have difficulty accessing the services they need, despite available primary care and community resources.
- Conditions
- Hypertension, Diabetes Mellitus, Type 2, Chronic Kidney Diseases, Ischemic Heart Disease
- Trial name
- ENCOMPASS (NCT04790604)
- Testing
- Community Health Navigator Program
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- University of Calgary
Type 1 Diabetes Mellitus
The Artificial Pancreas in Very Young Children With T1D - Pilot (KidsAP01)
The suggested clinical trial is part of the KidsAP project funded by the European Commission's Horizon 2020 Framework Programme.
- Trial name
- NCT03101865
- Testing
- FlorenceM
- Where
- 7 sites in Austria, Germany and 2 more
- Volunteers
- 24 people
- Sponsor
- University of Cambridge
Diabetes Mellitus
Plantar Faciitis and Diabetes Mellitus
Obesity is a risk factor for calcaneal spur (CS) formation which is supposed to originate from chronic plantar fasciitis. Diabetes mellitus may contribute to the risk of CS by decreased ability of tissue repair and increased…
- Trial name
- No acronym (NCT01259206)
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Diabetes Mellitus, Type 2
Effect of Metformin on Exercise-induced Lipolysis
The aim of this study is to investigate whether metformin has inhibitory effect on exercise-induced lipolysis in subcutaneous adipose tissue in healthy lean man.
- Trial name
- NCT03189732
- Testing
- Metformin Oral, Metformin local in AT, Exercise
- Where
- Czechia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Type 2 Diabetes
Metabolic Response to 3-day Fast Versus Carbohydrate-free Diet in Type 2 Diabetes
The investigators hypothesis is that a carbohydrate-free diet, ingested for 3 days, results in a change in blood glucose that is similar to the change observed after 3 days of fasting.
- Trial name
- CHO-free diet (NCT01469104)
- Testing
- 3 day fast, 3 day CHO-free diet
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Type 2 Diabetes Mellitus
Ranolazine When Added to Glimepiride in Subjects With Type 2 Diabetes Mellitus
This is a randomized, double-blind, placebo-controlled, parallel-group, multi-center study to determine the effect of ranolazine when added to glimepiride on glycemic control in adults with type 2 diabetes mellitus (T2DM) who are…
- Trial name
- NCT01494987
- Testing
- Ranolazine, Glimepiride, Diet
- Where
- 140 sites in United States, Czechia and 10 more
- Volunteers
- 431 people
- Sponsor
- Gilead Sciences
Type2 Diabetes
Effects of the Insulin Self Titration Education for Type 2 Diabetes Mellitus Patients
The purpose of the study was to evaluate the effects of an insulin self-titration education program on glycemic control, self-efficacy, and self-care behaviors in patients with type 2 diabetes.
- Trial name
- ISTE (NCT04736225)
- Testing
- Insulin Self-Titration Education Program
- Volunteers
- 120 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Type 2 Diabetes, Obesity
Effect of Glucagon and Glucagon-like Peptide-1 Co-agonism on Cardiac Function and Metabolism in Overweight Participants with Type 2 Diabetes
The study seeks to explore the cardiovascular effects of co-agonism at the glucagon and (glucagon-like peptide-1) GLP-1 receptor. Glucagon and exenatide will be intravenously infused into participants with type 2 diabetes (T2DM).
- Trial name
- COCONUT (NCT04307797)
- Testing
- 0.9% Sodium-chloride, Exenatide (50ng/min for 30 minutes loading followed by 25ng/min maintenance) and glucagon 12.5ng/kg/min, Glucagon 12.5ng/kg/min and 0.9% saline
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Diabetic Foot
The Effects of BAY1193397 on Skin Capillary Blood Flow and Transcutaneous Oxygen Pressure
The purpose of the study is to analyse skin blood flow in diabetic patients. The patients receive a single dose of placebo, 1 mg BAY1193397, and 5 mg BAY1193397.
- Trial name
- NCT03128320
- Testing
- BAY1193397
- Where
- United Kingdom
- Volunteers
- 23 people
- Sponsor
- Bayer
Diabetes Type 2
Project Dulce for Filipino-Americans With Type 2 Diabetes
This study aims to culturally adapt an existing American Diabetes Association (ADA)-recognized diabetes self-management and support or DSMES (Diabetes Self Management Education Support) program (Project Dulce) and integrate an…
- Trial name
- NCT05378620
- Testing
- Project Dulce + Dulce Digital
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- Scripps Whittier Diabetes Institute
Diabetes Mellitus Type 2
Comparison of Progressive Muscle Relaxation and Stretching Exercises in Diabetic Population
The goal of this clinical trial is to compare the effects of Progressive muscle relaxation and stretching exercises mediated by stress on heart rate variability, cortisol level, galvanic skin response and perceived stress scale.
- Trial name
- NCT06780878
- Testing
- Progressive muscle relaxation technique, Stretching exercises, Control Group
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Ischemic Heart Disease, Ischemic Stroke
Study to Compare 2 Doses of Polycap Versus Single Dose of Polycap With or Without Pottasium
This is a randomized double blind 2x2 factorial controlled trial to evaluate efficacy tolerability of low strength Polycap versus two doses of low strength Polycap in patients with stable cardiovascular disease in reducing blood…
- Conditions
- Ischemic Heart Disease, Ischemic Stroke, Peripheral Vascular Disease, Type 2 Diabetes Mellitus
- Trial name
- TIPSK (NCT01404078)
- Testing
- Single Dose Polycap, Double dose Polycap
- Volunteers
- 518 people
- Sponsor
- St. John's Research Institute
Type 2 Diabetes, Insulin Resistance
Effect of Insulin Sensitizer Therapy on Atherothrombotic and Inflammatory Profiles Associated With Insulin Resistance
The objective of this study is to determine whether targeted pharmacological improvement of insulin sensitivity will normalize the associated elevations of thrombotic and inflammatory cardiovascular disease (CVD) biomarkers in…
- Conditions
- Type 2 Diabetes, Insulin Resistance, Metabolic Syndrome
- Trial name
- NCT00443755
- Testing
- metformin, pioglitazone
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Mayo Clinic
Type 2 Diabetes
Efficacy and Safety Study of SHR117887 in Combination With Metformin in Patients With Type 2 Diabetes
SHR117887 is a new dipeptidyl peptidase(DPP)-4 inhibitor. This study aims to evaluate the efficacy and safety of SHR117887 in combination therapy with Metformin in patients with Type 2 Diabetes in Metformin monotherapy Who have…
- Trial name
- NCT01984489
- Testing
- SHR117887
- Volunteers
- 120 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Type 2 Diabetes, Obesity
Examination of the Anti-inflammatory and Insulin Sensitizing Properties of Doxycycline in Humans
Obesity is a heightened state of inflammation in which production of cytokines and matrix metalloproteinases (MMPs) result in loss of function of insulin receptors and insulin resistance.
- Trial name
- DOXY (NCT01375491)
- Testing
- Doxycycline
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Diabetes, Diabetes Mellitus, Type 2
A Non-interventional Study of Ability and Willingness to Pay for BIAsp 30 in a Real World Population With Type 2 Diabetes Mellitus (T2DM)
The purpose of this study is to collect information about the participant's ability and willingness to pay for NovoMix 30 using a modern device, which is prescribed to the participant by the study doctor for Type 2 Diabetes…
- Trial name
- NCT03374774
- Testing
- BIAsp 30
- Where
- 18 sites in India
- Volunteers
- 516 people
- Sponsor
- Novo Nordisk A/S
Diabetes Mellitus, Type 2, Bone Fragile
Bone Turnover in Type 2 Diabetes and Non-diabetes Controls (DiaMarv)
Type 2 diabetes (T2D) is related to an increased risk of major fractures which does written in English. The summary is used not only increase society health care costs, but also increase the morbidity and in the recruitment of…
- Trial name
- DiaMarv (NCT05585697)
- Testing
- None - crossectional
- Where
- Denmark
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
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