Clinical trials: Type 2 Diabetes, completed
Diabetes Mellitus, Type 2, Atherosclerosis
Safety & Effectiveness on Vascular Structure and Function of ACZ885 in Atherosclerosis and Either T2DM or IGT Patients
This study will evaluate the effect of ACZ885 on vascular function in patients with documented atherosclerotic disease and T2DM or IGT.
- Conditions
- Diabetes Mellitus, Type 2, Atherosclerosis, Prediabetic State
- Trial name
- NCT00995930
- Testing
- ACZ885
- Where
- 9 sites in United States, Canada and 3 more
- Volunteers
- 189 people
- Sponsor
- Novartis Pharmaceuticals
End-Stage Renal Disease, Type 2 Diabetes
Study to Determine the Efficacy of Real-time CGM in Preventing Hypoglycemia Among Insulin-treated Patients With DM2 on Hemodialysis, Compared to Standard of Care (POC BG)
The study is conducted to assess the efficacy of real-time CGM data in preventing hypoglycemia in patients with type 2 diabetes and end-stage kidney disease (ESKD), treated with insulin therapy and receiving hemodialysis.
- Trial name
- NCT04473430
- Testing
- Dexcom Real-time G6 Continuous Glucose Monitoring System (CGM), POC Glucose Testing
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Emory University
Type 2 Diabetes
Metabolic Causes of Thrombosis in Type 2 Diabetes - Question 1
The purpose of this study is to learn more about why patients with diabetes have increased heart attacks, strokes and other illnesses due to blood clots causing blockage of a blood vessel.
- Trial name
- NCT00574665
- Testing
- Hyperinsulinemic Hyperglycemic Clamp
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Diabetes Mellitus
Efficacy and Safety of Pioglitazone and Azilsartan in Treating Subjects With Type 2 Diabetes Mellitus
The purpose of this study is to determine the efficacy of pioglitazone, once daily (QD), combined with azilsartan in the treatment of subjects with Type 2 Diabetes Mellitus.
- Trial name
- NCT00762736
- Testing
- Pioglitazone and azilsartan, Pioglitazone
- Where
- 78 sites in United States, Argentina and 3 more
- Volunteers
- 704 people
- Sponsor
- Takeda
Diabete Type 2
Effectiveness of Diabetes Self-management Education on Glycaemic Control in Patients With T2DM
This is a randomized controlled trial assessing the effectiveness of a nurse led diabetes self management education(DSME) given over a 6 month period via mixed delivery strategy (in-person and via phone calls) on Hemoglobin…
- Trial name
- NCT07149311
- Testing
- Intervention
- Where
- Ghana
- Volunteers
- 74 people
- Sponsor
- Komfo Anokye Teaching Hospital
Chronic Periodontitis, Diabetes Mellitus
Effects of Adjunct Photodynamic Therapy in the Treatment of Type 2 Diabetic Patients With Chronic Periodontitis
Periodontal Diseases are considered the sixth complication of Diabetes Mellitus (DM). This close relationship between both diseases is characterized by mutual influence.
- Trial name
- NCT02627534
- Testing
- Ultrasonic debridement, Antimicrobial photodynamic therapy
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Prediabetes
Prospective Follow-up of a Cohort of Pre-diabetics in the North of France (DiabeNord)
The purpose of this study is to identify in prediabetic subjects, physiopathological changes involved in the evolution to type 2 diabetes mellitus and to identify new biomarkers of type 2 diabetes risk in this population.
- Trial name
- DiabeNord (NCT01432509)
- Testing
- Prediabetes screening and prospective follow-up over 5 years
- Where
- France
- Volunteers
- 207 people
- Sponsor
- Nantes University Hospital
Diabetes Mellitus, Type 2
Post Prandial Glucose Control Proof-of-Principle
The purpose of this study is to compare the postprandial glycemic response of subjects with type 2 diabetes when consuming a meal along with beverages containing various combinations of nutritional ingredients and fibers versus…
- Trial name
- NCT01326299
- Testing
- Nutritional ingredient, #1 Nutritional ingredient +Fiber, #2 Nutritional ingredient + Fiber
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Abbott Nutrition
Diabetes Mellitus, Type 2
A Study of LY900014 in Participants With Type 2 Diabetes Mellitus
The purpose of this study is to compare LY900014 with insulin lispro (Humalog) in participants with type 2 diabetes mellitus. The study will be conducted in participants with type 2 diabetes on insulin injection therapy to…
- Trial name
- NCT03305822
- Testing
- LY900014, Insulin Lispro
- Where
- Germany
- Volunteers
- 38 people
- Sponsor
- Eli Lilly and Company
Type 2 Diabetes
Does the Natural Medicinal Plant St John's Wort Affect the Glucose Tolerance in Healthy Individuals
The goal of the study is to examine if healthy individuals that ingest St John's wort will have a significantly difference in glucose tolerance.
- Trial name
- NCT01921881
- Testing
- St John's wort
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Diet, Healthy, Diabetes Mellitus, Type 2
Healthy Food Prescription Incentive Program
It is important for individuals with type 2 diabetes (T2DM) to adhere to a healthy dietary pattern to maintain optimal blood glucose levels and overall health.
- Conditions
- Diet, Healthy, Diabetes Mellitus, Type 2, Diabetes Complications
- Trial name
- NCT04725630
- Testing
- Healthy food incentive, Healthy food prescription
- Where
- Canada
- Volunteers
- 597 people
- Sponsor
- University of Calgary
Diabetes Mellitus, Type 2
Do Group Insulin Education Visits Reduce Barriers to Insulin Initiation?
The purpose of this research is to determine if meeting in a group with other subjects with diabetes can reduce barriers to starting insulin.
- Trial name
- NCT00645528
- Testing
- Insulin Education Class
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- US Department of Veterans Affairs
Diabetes, Diabetes Mellitus, Type 1
Observational Study to Evaluate Safety of Levemir® in Type 1 and Type 2 Diabetes
This study is conducted in Asia. The aim of this observational study is to evaluate the incidence of adverse events while using Levemir® under normal clinical practice conditions.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT00700765
- Testing
- insulin detemir
- Where
- Indonesia
- Volunteers
- 1,531 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes Mellitus
Drug-drug Interaction Study(Lobeglitazone, Warfarin)
The purpose of this study is to evaluate a pharmacokinetic drug interaction between lobeglitazone and warfarin in healthy subjects.
- Trial name
- NCT02002611
- Testing
- Lobeglitazone, Warfarin
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Heart Failure, ICD
SGLT2i As Anti Arrhythmic Therapy to Prevent Sudden Cardiac Deaths.
Failing heart negative remodeling alterations might provide electrical heterogeneity and cardiac remodeling, thus potentially contributing to the occurrence of ventricular arrhythmia and subsequent sudden cardiac death (SCD).
- Conditions
- Heart Failure, ICD, Diabetes Mellitus Type 2, SGLT2i
- Trial name
- NCT03366181
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- University of Campania Luigi Vanvitelli
Healthy
Evaluate the Pharmacokinetics of Digoxin When Coadministered With PEX168 in Healthy Adult Subjects
To assess the effect of PEX168 doses on the pharmacokinetics of digoxin in healthy subjects.To provide a scientific basis for clinical drug combination of PEX168.
- Trial name
- NCT02472236
- Testing
- PEX168, Digoxin
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
Diabetes
Utilizing Off-the-shelf Technology to Improve Diabetes Management in a Rural Population
This study is designed to see if rural patients with type II diabetes interacting with their clinic staff by providing daily updates of blood glucose levels will improve glucose control.
- Trial name
- NCT03105011
- Testing
- EpxDiabetes software
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Missouri-Columbia
Chronic Kidney Disease, Type 2 Diabetes Mellitus
A Study to Learn How Safe the Study Drug Finerenone is and How Well it Works in Indian People With Long-term Decrease in the Kidneys' Ability to Work Properly (Chronic Kidney Disease) Together With Type 2 Diabetes Mellitus
Researchers are looking for a better way to treat people with chronic kidney disease (CKD), a progressive decrease in the kidneys' ability to work properly, and type 2 diabetes (T2D).
- Trial name
- NCT05705271
- Testing
- Finerenone (Kerendia, BAY94-8862)
- Where
- 17 sites in India
- Volunteers
- 200 people
- Sponsor
- Bayer
Type 2 Diabetes Mellitus
Trial to Evaluate the Efficacy and Safety of Dapagliflozin in Japanese Type 2 Diabetes Mellitus Patients
The purpose of this study is to obtain information on efficacy and safety of dapagliflozin in Japanese patients with Type 2 Diabetes. This will be done by comparing the effect of dapagliflozin to placebo when given in oral doses.
- Trial name
- NCT00972244
- Testing
- Dapagliflozin
- Where
- 20 sites in Japan
- Volunteers
- 417 people
- Sponsor
- AstraZeneca
Type 2 Diabetes Mellitus
Study of Multiple Oral Doses of PF-07081532 in Adult Participants With Type 2 Diabetes Mellitus
This is a Phase 1, randomized, placebo-controlled, double-blind (investigator- and participant-blinded), sponsor-open study of PF-07081532.
- Trial name
- NCT05158244
- Testing
- PF-07081532
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Pfizer
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