Clinical trials: Type 2 Diabetes Mellitus (DM)
Type 2 Diabetes
INSPIRE Diabetes Study: Basal Bolus Insulin as Primary Treatment of Type 2 Diabetes
T2DM has become an American Epidemic. Currently 8% of the US population has diabetes and rates may be as high as 33% by the year 2050 (1).
- Trial name
- INSPIRE (NCT01087567)
- Testing
- Intensive insulin, Routine Care
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Ohio University
Type 2 Diabetes Mellitus
Placebo Controlled, Dose Escalation Study in Subjects With Type 2 Diabetes Mellitus Being Treated With Sulfonylurea
The purpose of this study is to provide an initial assessment of the safety, tolerability and efficacy of ISIS 113715 in combination with sulfonylurea in type 2 diabetes subjects.
- Trial name
- NCT00455598
- Testing
- ISIS 113715
- Where
- 39 sites in Poland, Romania and 1 more
- Volunteers
- 88 people
- Sponsor
- Ionis Pharmaceuticals, Inc.
Type 2 Diabetes Mellitus
Cilostazol Versus Aspirin for Primary Prevention of Atherosclerotic Events
This multi-center, randomized controlled study aims to evaluate the efficacy of Cilostazol versus Aspirin for primary prevention of atherosclerotic events with Korean type 2 Diabetes Mellitus (DM) patients.
- Trial name
- CAPPA (NCT00886574)
- Testing
- Cilostazol, Aspirin
- Where
- 6 sites in South Korea
- Volunteers
- 400 people
- Sponsor
- Hanyang University
Type 2 Diabetes Mellitus
Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (LixiLan) to Lixisenatide on Top of Oral Anti-diabetic Drugs (OADs) With Type 2 Diabetes in Japan
Primary Objective: To compare LixiLan to lixisenatide in glycated hemoglobin (HbA1c) change from baseline to Week 26 in patients with type 2 diabetes mellitus.
- Trial name
- LIXILAN JP-O1 (NCT02749890)
- Testing
- Insulin glargine/Lixisenatide (HOE901/AVE0010), Lixisenatide (AVE0010), Oral anti-diabetic drugs
- Where
- 61 sites in Japan
- Volunteers
- 321 people
- Sponsor
- Sanofi
Dyslipidemia, Type 2 Diabetes Mellitus
Management of Dyslipidemia in Adult Type 2 Diabetes Patients in India
The purpose of study to assess the control of dyslipidemia in the Indian diabetic population treated with any hypolipidemic agent.
- Trial name
- SOLID (NCT01292018)
- Volunteers
- 5,400 people
- Sponsor
- AstraZeneca
Diabetes Mellitus, Type 2 DM
Safety and Efficacy Assessment of Unani Formulation 'Dolabi' in Management of Diabetes Mellitus Type II
Diabetes is a chronic health condition that affects millions of people worldwide. In recent years, Pakistan has witnessed a significant increase in the prevalence of diabetes, making it a major public health concern.
- Trial name
- NCT06841497
- Testing
- Dolabi
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Hamdard University
Diabetes Mellitus, Type 2
Glufast On Insulin Glargine Trial in Type 2 DM
We will evaluate the efficacy and safety of combination therapy of 10 mg mitiglinide or 0.2mg voglibose with insulin glargine for 16 weeks after single administration of insulin glargine for 4 weeks in type 2 diabetic patients…
- Trial name
- GLORIA (NCT00663884)
- Testing
- Mitiglinide, Voglibose
- Where
- South Korea
- Volunteers
- 167 people
- Sponsor
- JW Pharmaceutical
Dyslipidemia, Type 2 Diabetes Mellitus
Postprandial Fatty Acids and FABP2 in Type 2 Diabetes Mellitus (DM)
This study will be conducted in type 2 diabetic patient's to evaluate the if there is a different response of serum lipids after a standard meal (rich in saturated fatty acids) in patients who have the presence of a genetic…
- Trial name
- NCT00634673
- Testing
- sandwich
- Where
- Brazil
- Volunteers
- 26 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Type 2 Diabetes Mellitus
Comparative Interventional Study to Evaluate the Role of LRYGBP, LSG & SMM
A Comparative Interventional Study to Evaluate the Role of Laparoscopic Roux-en-Y Gastric Bypass (LRYGBP), Laparoscopic Sleeve Gastrectomy (LSG) and Standard Medical Management (SMM) in Patients of Type II Diabetes Mellitus (DM)…
- Trial name
- NCT04058730
- Testing
- Laparoscopic Roux en Y Gastric by pass surgery, Laparoscopic Sleeve Surgery, Standard Medical Management
- Where
- 2 sites in India
- Volunteers
- 150 people
- Sponsor
- Max Institute of Minimally Access, Metabolic & Bariatric Surgery
Type 2 Diabetes Mellitus
The Role of Arachidonic Acid Metabolites, From Patients With Metabolic Syndrome
The purpose of this study is to determine whether an increase in lipid bodies in leukocytes will lead to an increase in eicosanoid production.
- Trial name
- NCT02498119
- Where
- Malaysia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Diabetes Mellitus, Type 2, Diastolic Dysfunction
PDD in Type 2 Diabetes w/wo Diastolic Dysfunction
This study will advance the investigator's knowledge of the integrated cardiorenal and humoral physiology in type 2 diabetic patients with and without pre-clinical diastolic dysfunction, and test a novel therapeutic strategy…
- Trial name
- NCT03744975
- Testing
- LCZ 696
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Diabetes Mellitus, Type 2
Self-Care for Older People With Diabetes Mellitus
In Singapore, the prevalence of diabetes was approximately 12.8% in 2014 and was projected to rise to 22.7% in 2035. In 2015, the International Diabetes Federation (IDF) reported that Singapore has the second highest proportion…
- Trial name
- SCOPE-DM (NCT03890991)
- Testing
- SCOPE-DM, SCOPE-DM with 3 months' supply of glucometer, SCOPE-DM with 6 months' supply of glucometer
- Where
- Singapore
- Volunteers
- 320 people
- Sponsor
- National University of Singapore
Diabetes Mellitus (DM), Type 2 Diabetes Mellitus (T2DM)
Improving the Activation Level of Diabetic Individuals
This study was planned to determine the activation levels of diabetic individuals and to improve the activation level. The study, planned as a descriptive and experimental type, is an attempt to increase the activation level of…
- Conditions
- Diabetes Mellitus (DM), Type 2 Diabetes Mellitus (T2DM), Patient Activation, Diabetes Self-management
- Trial name
- NCT06973954
- Testing
- Text Message Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Blood Pressure
Lifestyle Changes in Patients With Type 2 Diabetes Mellitus and Hypertension
Data obtained in hypertensive patients without diabetes suggest that increased association of non-pharmacological treatment in patients with diabetes and hypertension may be associated with an improvement in blood pressure…
- Trial name
- NCT01461330
- Testing
- DASH diet plus exercise, ADA diet
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Controlled Type 2 Diabetic Patients With Periodontitis
Clinical and Radiographic Evaluation of Subgingival 1% Metformin Gel Versus 0.05% Zoledronate Gel as an Adjunct to MINST of Intrabony Defects in Controlled Type 2 DM
The present randomized placebo-controlled trial aims to evaluate and compare the clinical and radiographic efficacy of subgingivally delivered 0.05% zoledronate gel and 1% metformin gel as adjuncts to minimally invasive…
- Trial name
- NCT07753317
- Testing
- All participants will receive MINST
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Diabetes (DM)
A Study to Investigate a Transdermal Continuous Glucose Monitoring System in Diabetic Patients for a Period of 28 Days
Single-centre, open label (unblinded). A maximum of 48 patients will be enrolled in 4 Cohorts of 10 patients and 2 potential replacements each. Diabetic patients (type 1 and 2).
- Trial name
- FiberSense (NCT06868043)
- Testing
- FiberSense System
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- EyeSense GmbH
Diabetes Mellitus, Type 2
Phase 3 Study to Evaluate the Efficacy and Safety of ORMD-0801 in Subjects With Type 2 Diabetes Mellitus
To compare the efficacy of ORMD-0801 to placebo in improving glycemic control as assessed by A1C in inadequately controlled T2DM subjects on diet control alone or on diet control and metformin monotherapy or two or three oral…
- Trial name
- NCT04817215
- Testing
- ORMD-0801
- Volunteers
- 608 people, healthy volunteers welcome
- Sponsor
- King Hamad University Hospital, Bahrain
Diabetes Mellitus, Type 2
The Effect of Metformin Treatment on Thyroid Hormone Metabolism in Euthyroid Patients With Type 2 Diabetes Mellitus
Aim: To investigate the effects of metformin treatment on thyroid hormone metabolism in euthyroid patients with type 2 diabetes mellitus.
- Trial name
- NCT00463502
- Testing
- Metformin
- Sponsor
- Haydarpasa Numune State Hospital
Type 2 Diabetes
Financial Incentives And Nurse Coaching to Enhance Diabetes Outcomes (FINANCE-DM)-1
The objective of this protocol is to answer the questions: 1) Are financial incentives layered upon nurse education and home telemonitoring superior to nurse education and home telemonitoring alone in improving metabolic control…
- Trial name
- FINANCE-DM (NCT04203173)
- Testing
- FINANCE-DM, Active Comparator
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- State University of New York at Buffalo
Type 2 Diabetes Mellitus
Efficacy and Safety of CWP-0403 Compared to Sitagliptin in Patients With Type 2 Diabetes Mellitus Insufficiently Controlled With Metformin Alone
This trial is to evaluate the efficacy and safety of CWP-0403 compared to Sitagliptin by proving non-inferiority in patients with type 2 Diabetes Mellitus insufficiently controlled with metformin alone.
- Trial name
- CWP-DIANA-302 (NCT01529541)
- Testing
- Anagliptin, Sitagliptin
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- JW Pharmaceutical