Clinical trials: Type 2 Diabetes Mellitus (T2D)
Type 2 Diabetes Mellitus
Empowering Rural African American Women and Communities to Improve Diabetes Outcomes
The EMPOWER diabetes program is a year-long, community-based program designed to enhance diabetes management in rural African American women with uncontrolled diabetes.
- Trial name
- EMPOWER (NCT01806194)
- Testing
- Lifestyle Counseling, Educational Control Arm
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- East Carolina University
Periodontitis, Type 2 Diabetes Mellitus (T2DM)
Para-Probiotic Oral Care in Periodontal Patients With Type 2 Diabetes
This randomized controlled clinical trial aims to evaluate the effectiveness of a para-probiotic-based oral care protocol in improving periodontal health and glycemic control in patients with type 2 diabetes mellitus (T2DM).
- Trial name
- PPDM2 (NCT07069166)
- Testing
- Para-probiotic oral care, Chlorhexidine oral care
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Atrial Fibrillation, Type 2 Diabetes
Prevalence and Factors Associated With Atrial Fibrillation in Patients With Type 2 Diabetes
This case-control study was conducted at Burapha University Hospital. The 12-lead electrocardiography recordings of type 2 diabetes patients were reviewed by a cardiologist to confirm the presence of atrial fibrillation.
- Trial name
- NCT06174129
- Testing
- Routine examinations
- Where
- Thailand
- Volunteers
- 427 people
- Sponsor
- Burapha University
Diabetes Mellitus, Psychological Distress
Prevalence of Diabetes-related Distress Among Patients Living With Type 2 Diabetes in a University Hospital Center and Identification of Its Associated Factors.
Diabetes-related distress is a psychological construct associated with poorer glycaemic control in people living with diabetes. In France, few data are available on this topic and none focus specifically on adults with type 2…
- Trial name
- DIAMIND (NCT07392437)
- Testing
- Questionnaire and Physical Exam
- Where
- France
- Volunteers
- 290 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Type 2 Diabetes
The Swiss Glucose Variability Study
The purpose of this study is to explore long term glucose variability of a combination therapy of metformin and vildagliptin compared to a metformin - gliclazide combination.
- Trial name
- NCT01426737
- Testing
- Vildagliptin
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University of Zurich
Type 2 Diabetes Mellitus, Cardiovascular Autonomic Dysfunction
Nurse-Led Self-Management and Breathing Intervention in Type 2 Diabetes
Brief Summary This study evaluated the effect of a structured nurse-led home-based self-management and paced-breathing intervention on cardiovascular autonomic function and blood pressure among adults with type 2 diabetes…
- Trial name
- NCT07847177
- Testing
- Structured Nurse-Led Home-Based Self-Management and Paced-Breathing Program
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Aziza Ibrahim Mohamed
Diabetes Mellitus, Type 2
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Subcutaneous Injections of HRS9531 in Patients With Type 2 Diabetes Mellitus
The main purpose of this study is to assess the safety and tolerability of multiple subcutaneous injections of HRS9531 in patients with type 2 diabetes mellitus who have suboptimal glycaemic control after conventional lifestyle…
- Trial name
- NCT05516966
- Testing
- HRS9531, Dulaglutide Injection
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
Diabete Type 2, Regurgitation
Investigation of Gastric Emptying by Gastric Ultrasonography in Diabetic Patients Treated With GLP-1 Receptors
Treatment with semaglutide slows down gastric emptying , food remains in the stomach for a longer period of time. This slowing has important implications for anesthesia management.
- Conditions
- Diabete Type 2, Regurgitation, Pulmonary Aspiration During Anaesthetic Induction
- Trial name
- SAGUSE (NCT07506356)
- Where
- Switzerland
- Volunteers
- 38 people
- Sponsor
- University Hospital, Geneva
Platelet Indices, Type 2 Diabetes
Platelet Changes in Type 2 Diabetes
This study examines changes in platelet indices in people with type 2 diabetes compared to healthy people. It checks if these changes relate to inflammation markers (like hs-CRP) and blood sugar control.
- Conditions
- Platelet Indices, Type 2 Diabetes, Inflammatory Markers
- Trial name
- NCT07363122
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Coronary Artery Disease, Diabetes Mellitus, Type 2
PIPAF Platelets in the Pathogenesis of Ageing Associated Frailty
This is a prospective observational study aimed at testing the existence of an association between frailty, inflammatory status, and degree of platelet activation and reactivity in elderly subjects with type 2 diabetes or…
- Conditions
- Coronary Artery Disease, Diabetes Mellitus, Type 2, Alzheimer Disease
- Trial name
- PIPAF (NCT05798637)
- Testing
- Standard of care
- Where
- 2 sites in Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera di Perugia
Type 2 Diabetes, Renal Impairment
A Clinical Trial of the Study Medicine (PF-07081532) in People With Diabetes and Kidney Dysfunction
The purpose of this study is to understand the effects of kidney functional impairment may have on the study medicine (PF-07081532).
- Trial name
- NCT05510245
- Testing
- PF-07081532
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Pfizer
Type 2 Diabetes
Comprehensive Care Protocol in New Diagnosis of Type 2 Diabetes Mellitus and Associated Comorbidities in Primary Care
Introduction Type 2 Diabetes is a very prevalent chronic disease in our environment. It usually exists with other chronic diseases.
- Trial name
- PICDM2 (NCT03990857)
- Testing
- Comprehensive care protocol in new diagnosis of Type 2 Diabetes Mellitus and associated comorbidities in Primary Care
- Where
- Spain
- Volunteers
- 123 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Diabetes Complications, Diabetes Mellitus, Type 2
Comparison of Novo Rapid 30 Mix Injection FlexPen® and Humalog 25 Mix Injection KwikPen® in Type 2 Diabetic Patients
The purpose of this study is to investigate patient's usability, preference and blood glucose control for the new prefilled disposable insulin lispro mixture (Humalog Mix 25 injection KwikPen®).
- Trial name
- NCT00806975
- Testing
- KwikPen® and FlexPen®
- Where
- Japan
- Volunteers
- 200 people
- Sponsor
- Nagaoka Red Cross Hospital
Type 2 Diabetes Mellitus
Sitagliptin/Metformin Fed Bioequivalence Study (0431A-080)
This study will demonstrate the bioequivalence of metformin after single dose administration of sitagliptin/metformin 50/500 mg fixed dose combination (FDC) tablet and concomitant administration of single doses of sitagliptin 50…
- Trial name
- NCT00929201
- Testing
- Sitagliptin phosphate/metformin hydrochloride FDC, Sitagliptin phosphate, Metformin hydrochloride
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Type 2 Diabetes, Hypertension
Impact of Clinical Pharmacist-Led Intervention on Management of Diabetic Hypertensive Patients in Eastern Nepal
Diabetic-Hypertensives are at a higher risk of premature microvascular and macrovascular complications than diabetes alone. Proper lifestyle management, diet, disease monitoring, and medication adherence is essential in achieving…
- Trial name
- NCT05707481
- Testing
- Clinical Pharmacist-Led Educational Intervention
- Where
- Nepal
- Volunteers
- 92 people
- Sponsor
- Chettinad Academy of Research and Education (Deemed to be University)
Obesity, Type 2 Diabetes
MagDI Australia Study
The objective of the MagDI Australia Study is to evaluate the feasibility / performance, safety, and initial efficacy of the MagDI System in eligible participants who are indicated for a duodeno-ileal (small bowel) side-to-side…
- Trial name
- NCT06473831
- Testing
- Magnet System, DI Biofragmentable
- Where
- 4 sites in Australia
- Volunteers
- 25 people
- Sponsor
- GT Metabolic Solutions, Inc.
Diabetes Type 2
Biphasic Insulin Aspart Versus NPH Plus Regular Human Insulin in Type 2 Diabetic Patients
Glycemic control is fundamental in the management of diabetes mellitus .If lifestyle intervention and full tolerated doses of one or two oral glucose lowering drugs (OGLDs) fail to achieve or sustain glycemic goals, insulin…
- Trial name
- NCT01889095
- Testing
- BIAsp 30, NPH/Reg
- Where
- Iran
- Volunteers
- 160 people
- Sponsor
- Tehran University of Medical Sciences
Type 2 Diabetes Mellitus, Hypertension
Evaluation of Improved Outcomes Among Ambulatory Diabetes and/or Hypertensive Patients - an Intervention Study (CPCLINT)
The goal of this interventional study is to compare improved outcomes among diabetes and/or hypertensive patients sequel to educational intervention.
- Trial name
- CPCLINT (NCT05996601)
- Testing
- Educational intervention
- Where
- Nigeria
- Volunteers
- 400 people
- Sponsor
- University of Ibadan
Haemodialyzed, Type 2 Diabetes
A Prospective, Multicenter, Randomized, Open-label Study of 12 Week Duration to Evaluate the Effect of VILDagliptin Added to Insulin on Glycaemic Control in haemoDIALyzed Patients With Type 2 Diabetes: Probe Analysis of CGM
Diabetes is a major concern for dialysis units, as it is now the most common cause of end-stage renal disease in France. In 2010 at initiation of dialysis treatment, more than one patient out of two had at least one…
- Trial name
- NCT02176681
- Testing
- Vildagliptin (Galvus), Insulin
- Where
- 13 sites in France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Strasbourg, France
Diabetes Mellitus, Type 2, Diabetes Complications
Electronic Diabetes Tune-Up Group (eDTU) for African Americans
The primary aims of this study are: 1. To test the acceptability and feasibility of the electronic DTU intervention (eDTU) that has been adapted for cultural relevance and online delivery compared to waitlist control and the…
- Trial name
- NCT06321029
- Testing
- Diabetes Tune-Up Group
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Indiana University
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