Clinical trials: Type 2 Diabetes Prevention
Type 2 Diabetes
Diabetes Prevention in Clinical Practice.
We randomize individuals with impaired glucose tolerance to one of three arms for degree of physical activity: 1. Continue with your current life style; 2. Ordinary life activities for increased physical activity; 3.
- Trial name
- DIAVIP (NCT01834378)
- Testing
- Low intensity intervention, High intensity intervention.
- Volunteers
- 96 people
- Sponsor
- Göteborg University
Type 1 Diabetes Mellitus With Diabetic Nephropathy
dApagliflozin SC0062 and Prevention of Renal Injury; a Randomized Evaluation
The aim of this study is to test the hypothesis that dapagliflozin (SGLT2 inhibitor) and SC0062 (ERA) combination therapy augments nephroprotection and mitigates fluid retention and ketogenesis in people with T1D through…
- Trial name
- ASPIRE-1 (NCT06072326)
- Testing
- Dapagliflozin (Forxiga®), SC0062 strength 10mg, SC0062 and dapagliflozin
- Where
- 5 sites in Denmark, Finland
- Volunteers
- 36 people
- Sponsor
- University Medical Center Groningen
Diabetes Mellitus, Type 2, Gestational Diabetes
Prevention of Type 2 Diabetes and Gestational Diabetes Among Women in Kisantu, Democratic Republic of Congo
This study aims to develop and implement a long-term program focused on the prevention of type 2 diabetes Mellitus (T2DM) and gestational diabetes mellitus (GDM) in women of reproductive age through lifestyle modification.
- Trial name
- KIS-Antwerp (NCT05039307)
- Testing
- Educational and motivational strategy
- Where
- 6 sites in Democratic Republic of the Congo
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Pre-diabetes
Motivational Instant Messaging and E-diabetes Prevention Programme for High Risk of Type 2 Diabetes
The overall aim of this feasibility trial is to assess the effectiveness of a wearable technology and an e-diabetes prevention programme delivered via a smartphone application, including motivational messaging, in reducing weight…
- Trial name
- NCT02919397
- Testing
- Wearable technology, Diabetes Prevention Programme educational material, Motivational messaging
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- King's College London
Type 2 Diabetes
Multifactorial Intervention in Type 2 Diabetes - Italy
Despite several clinical trials have clearly demonstrated that the correction of a single cardiovascular risk factor in patients with type 2 diabetes decreases the incidence of myocardial infarction and other cardiovascular…
- Trial name
- MINDIT (NCT01240070)
- Testing
- Intensive care
- Where
- 9 sites in Italy
- Volunteers
- 1,461 people
- Sponsor
- University of Parma
Pre-diabetes
More Health Less Diabetes
The "More Health, Less Diabetes" project is a hybrid randomized controlled trial to prevent type 2 diabetes in individuals at risk through structured exercise and lifestyle education.
- Trial name
- MHLD (NCT07079722)
- Testing
- Exercise
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Diabetes Mellitus, Type 2/Prevention & Control, Diabete Type 2
Therapeutic Adherence in Type 2 Diabetes
A quasi-experimental, non-randomized, prospective, longitudinal study comparing the use of WhatsApp messaging versus the SMART technique in patients with type 2 diabetes to improve treatment adherence
- Conditions
- Diabetes Mellitus, Type 2/Prevention & Control, Diabete Type 2, Treatment Adherence
- Trial name
- NCT07837856
- Testing
- Group I (WhatsApp) motivational and educational messages delivered periodically, Group II: To implement the SMART method
- Where
- Mexico
- Volunteers
- 250 people
- Sponsor
- Instituto Mexicano del Seguro Social
Prediabetes, Gestational Diabetes Mellitus
Assessing the Effectiveness of a Weight Watchers-based Lifestyle Intervention for the Primary Prevention of Type 2 Diabetes
This study is a randomized pilot study to assess the applicability of the Weight Watchers model for lifestyle modification to the primary prevention of type 2 diabetes.
- Conditions
- Prediabetes, Gestational Diabetes Mellitus, Obesity
- Trial name
- NCT02000024
- Testing
- Weight Watchers, National Diabetes Education Program
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Indiana University
Obesity, Diabetes Mellitus
Type 2 Diabetes Primary Prevention for At Risk Girls
Purpose: To evaluate two approaches to prevent obesity and type 2 diabetes in young girls. The Need: We are experiencing an epidemic of childhood obesity.
- Conditions
- Obesity, Diabetes Mellitus, Pre Diabetes
- Trial name
- NCT00063674
- Testing
- Nutrition Education, After-school dance class
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
CHD, AMI
Lifestyle Intervention in a General Population for Prevention of Ischaemic Heart Disease
In spite of declining trend coronary heart disease (CHD) is still a leading cause of morbidity and mortality. Many years of epidemiological research have identified several risk factors for CHD.
- Conditions
- CHD, AMI, CVD, Type 2 Diabetes
- Trial name
- NCT00289237
- Testing
- Lifestyle intervention
- Where
- Denmark
- Volunteers
- 61,301 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Obesity, Overweight
PACE-iDP: An Intervention for Youth at Risk for Diabetes
This randomized control study (sponsored by the NIH, NIDDK) is aimed at reducing BMI in overweight adolescents at risk for the development of type 2 diabetes.
- Conditions
- Obesity, Overweight, Diabetes
- Trial name
- NCT00412165
- Testing
- Cell Phone, Weekly access to interactive web site, Group
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- University of California, San Diego
Type 2 Diabetes Mellitus, Pre-diabetes
Acute Effects of Cold-induced Shivering on 24-hour the Glucose Profile in Metabolically Compromised Populations
Type 2 Diabetes Mellitus (T2DM) and its associated comorbidities pose a major health concern worldwide. Although lifestyle strategies, such as exercise and diet-induced weight loss are effective interventions to counteract the…
- Trial name
- SHIVER (NCT05576025)
- Testing
- Lifestyle intervention (cold exposure)
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Maastricht University Medical Center
Type 2 Diabetes
Chronotherapy with Low-dose Aspirin for Primary Prevention
Brief summary: Aspirin (ASA) has been shown to provide marked benefits in primary and secondary prevention of cardiovascular events.
- Trial name
- CARING (NCT00725127)
- Testing
- aspirin
- Where
- 19 sites in Spain
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- University of Vigo
Cardiovascular Diseases, Diabetes Mellitus Type 2
"Screening for Change: Early Risk Detection and Integrated Prevention for Diabetes and Cardiovascular Diseases in the Marche Region"
This study aims to test the feasibility of a new systematic screening program to allow the early detection of individuals aged 50 years at risk of type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVDs) in the resident…
- Trial name
- JAC_AST (NCT07344701)
- Testing
- Screening program
- Where
- 2 sites in Italy
- Volunteers
- 2,951 people
- Sponsor
- Marche Region Regional Health Agency
Diabetes Mellitus Type 2
Individualized Lifestyle Intervention in Subjects With Prediabetes
The purpose of this prospective randomized multicenter intervention study is to determine whether in the prevention of Diabetes an intensified lifestyle intervention is superior to a conventional lifestyle intervention in high…
- Trial name
- PLIS (NCT01947595)
- Testing
- intensified lifestyle intervention, normal lifestyle intervention, Single lifestyle advice
- Where
- 7 sites in Germany
- Volunteers
- 1,145 people
- Sponsor
- University Hospital Tuebingen
Gestational Diabetes Mellitus, Type 2 Diabetes Mellitus
Diabetes Prevention Among Post-partum Women With History of Gestational Diabetes
The purpose of the STAR-MAMA intervention is to develop a patient-tailored telephone-base counseling intervention for young Latino women who are at high risk of diabetes.
- Trial name
- Star-Mama (NCT02240420)
- Testing
- Life Style Counseling (Star-Mama)
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- University of California, San Francisco
Obesity, Childhood, Type2Diabetes
Telehealth Lifestyle Program for Black Adolescent Girls at Risk for Type 2 Diabetes
The aim of this study is to look at changes in diabetes-related risk factors in Black adolescent girls who are at risk for type 2 diabetes and their primary female caregiver after both participating in a 12-week telehealth…
- Trial name
- NCT05396443
- Testing
- Black Girls for Wellness Telehealth
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- Cornell University
Diabetes Mellitus, Type 2
Decreasing Cardiovascular Risk for Patients With Diabetes
Cardiovascular disease (CVD) complications are the leading cause of diabetes mellitus (DM)-related morbidity and mortality, creating a significant burden on the public health system.
- Trial name
- NCT04874116
- Testing
- Office Guidelines Applied to Practice (Office-GAP) + Mobile text messaging, Mobile text messaging
- Where
- United States
- Volunteers
- 409 people
- Sponsor
- Michigan State University
Cardiovascular Risk Factor, Diabetes Mellitus, Type 2
Evaluation of a Physical Activity Referral Scheme
The study will evaluate the effectiveness of a co-developed exercise referral scheme. Participants will be recruited to one of three groups 1. Co-developed exercise referral scheme, 2. Usual care exercise referral scheme, 3.
- Conditions
- Cardiovascular Risk Factor, Diabetes Mellitus, Type 2, Anxiety, Depression
- Trial name
- NCT03490747
- Testing
- Physical activity referral scheme, Usual care exercise referral scheme
- Where
- United Kingdom
- Volunteers
- 68 people
- Sponsor
- Paula Watson
Metabolic Syndrome
Metabolic Syndrome Risk Factor in IGT: STOP-NIDDM Trial
The aim of the study was to analyse the independent and joint effects of the components of the metabolic syndrome (MetS) on the incidence of diabetes in people with impaired glucose tolerance (IGT) and to assess the effect of…
- Trial name
- NCT00629213
- Testing
- acarbose
- Where
- Germany
- Volunteers
- 1,429 people
- Sponsor
- GWT-TUD GmbH