Clinical trials: Type 2 Diabetes Prevention
Type 2 Diabetes Mellitus, Obesity
Soluble Dietary Fibres in the Prevention of Type 2 Diabetes Mellitus
Controlling the glycemic impact of foodstuffs (by reducing the glycemic load of the diet by using soluble dietary fibres) may reduce the glycemic or insulinemic response.
- Trial name
- NCT01163006
- Testing
- Polydextrose and soluble gluco fibre
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
At Risk for Type 2 Diabetes Mellitus, Pre Diabetes
Primary and Secondary Prevention of Type 2 Diabetes Mellitus in Clark County
This pilot and feasibility study aims to assess the effectiveness of a nutrition education intervention using the Cooking Matters for Adults Curriculum (SNAP-Ed).
- Trial name
- NCT06387797
- Testing
- Cooking Matters for Adults (CMA+), Cooking Matters for Adults (CMA)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Type 2 Diabetes, Obesity
Obesity and Diabetes Prevention Through Science Enrichment
Type 2 diabetes and obesity in children continue to increase at alarming rates with devastating results. However, both these metabolic diseases are largely preventable through adoption of a healthy lifestyle, an understanding of…
- Trial name
- DKENERGY (NCT00541879)
- Testing
- Program ENERGY, comparison
- Where
- United States
- Volunteers
- 2,909 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Type 2 Diabetes, Overweight
INcreTin-based thERapies for Cardiovascular Event PrevenTion in Patients With and Without ASCVD (INTERCEPT-ASCVD)
Investigators are building an empirical evidence base for real world data through large-scale emulation of randomized controlled trials.
- Conditions
- Type 2 Diabetes, Overweight, ASCVD
- Trial name
- INTERCEPT (NCT07417618)
- Testing
- Dulaglutide, Semaglutide, Tirzepatide
- Where
- United States
- Volunteers
- 60,000 people
- Sponsor
- Brigham and Women's Hospital
Diabetes Mellitus, Type 2, PreDiabetes
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
TRANSFORM is a prospective, randomized, open blinded endpoint (PROBE), event-driven, pragmatic trial in patients who are at increased risk for atherosclerotic cardiovascular (CV) disease but with no known symptomatic CV disease.
- Conditions
- Diabetes Mellitus, Type 2, PreDiabetes, Metabolic Syndrome
- Trial name
- TRANSFORM (NCT06112418)
- Testing
- The Cleerly CAD Staging System
- Where
- 125 sites in United States
- Volunteers
- 7,500 people, healthy volunteers welcome
- Sponsor
- Cleerly, Inc.
Diabetes Mellitus, Type 2
A Randomized Trial of Diabetes Prevention Through Lifestyle Change in India
People from the Indian subcontinent are more likely to get diabetes, even at younger ages. The Diabetes Community Lifestyle Improvement Program (D-CLIP) will test in a randomized trial if a culturally specific, community-based…
- Trial name
- D-CLIP (NCT01283308)
- Testing
- Lifestyle Intervention, Standard of Care
- Where
- India
- Volunteers
- 599 people, healthy volunteers welcome
- Sponsor
- Emory University
Type 2 Diabetes
TEEN HEED: An Adolescent Diabetes Prevention Intervention Incorporating Novel Mobile Health Technologies
The number of youth with type 2 diabetes in the U.S. is projected to increase by a staggering 49 percent by 2050, with higher rates among minority youth.
- Trial name
- NCT05560386
- Testing
- Text messaging, Virtual workshop
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Diabetes Mellitus, Non-Insulin-Dependent, Glucose Intolerance
Diabetes Prevention Program
The Diabetes Prevention Program is a nationwide clinical study to answer the question: Can Type 2 diabetes (also called noninsulin-dependent or adult-onset diabetes) be prevented or delayed? The study has recruited volunteers…
- Trial name
- NCT00004992
- Testing
- Intensive lifestyle, Metformin
- Where
- United States
- Volunteers
- 3,234 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type 2 Diabetes
Type 2 Diabetes Secondary Prevention
Three hundred and ninety height diabetic patients were educated during a week of hospitalisation (nutritional and physical-activity advices).
- Trial name
- RP2 (NCT01207349)
- Testing
- Secondary prevention intervention trial, standard follow up
- Where
- France
- Volunteers
- 398 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Diabetes
Hypoglycemia Prevention in High-Risk Type 2 Diabetes Patients
Severe low blood sugar (hypoglycemia) is a serious problem for people with diabetes. It can lead to dangerous falls, heart problems, memory issues, and even death.
- Trial name
- NCT06746714
- Testing
- Proactive population care (active application of HOAP principles in patients flagged as high risk for hypoglycemia), Usual care, after system-side dissemination of HOAP
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Kaiser Permanente
Gestational Diabetes Mellitus in Pregnancy
Lifestyle Intervention IN Gestational Diabetes (LIVING)
Investigators have taken the learning from various programs to develop a new lifestyle program (LIVING) that has a high probability of being feasible, acceptable and cost-effective in the South Asian context for women with prior…
- Trial name
- LIVING (NCT03305939)
- Testing
- Life style Intervention
- Where
- 20 sites in Bangladesh, India and 1 more
- Volunteers
- 1,612 people, healthy volunteers welcome
- Sponsor
- The George Institute
Obesity and Type 2 Diabetes, Diet Modification
Mobile Regulation of Craving Training (mROC-T) to Improve Dietary Intake in Rural Adolescent Girls
The goal of this clinical trial is to test if a regulation of craving training intervention in the form of a mobile phone app can increase fruit and vegetable intake in adolescent girls ages 14-18 years of age.
- Trial name
- ROC Teens! (NCT06723028)
- Testing
- Regulation of craving training
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Wyoming
Obesity, Overweight
PACE-iDP: An Intervention for Youth at Risk for Diabetes
This randomized control study (sponsored by the NIH, NIDDK) is aimed at reducing BMI in overweight adolescents at risk for the development of type 2 diabetes.
- Conditions
- Obesity, Overweight, Diabetes
- Trial name
- NCT00412165
- Testing
- Cell Phone, Weekly access to interactive web site, Group
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- University of California, San Diego
Type 2 Diabetes
Glycemic Relapse Prevention: Maintenance Dose Assessment
This purpose of this study is to determine the optimal frequency of maintenance intervention needed to prevent glycemic relapse.
- Trial name
- NCT00362193
- Testing
- Telephonic diabetes care
- Volunteers
- 165 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Serious Mental Illness, Type 2 Diabetes
MetSense Pilot and Feasibility
People with serious mental illness have high risk for type 2 diabetes due to multiple risk factors, including the metabolic side effects of psychotropic medications that are used to treat these conditions.
- Trial name
- MetSenseP&F (NCT07264062)
- Testing
- MetSense Risk Flag, Usual Care
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Kaiser Permanente
Eating Disorders, Type 2 Diabetes
Diabetes Body Project 2
The purpose of this study is to test the feasibility and effectiveness of an eating disorder prevention program specifically targeted for women with type 2 diabetes (T2D) called the Diabetes Body Project 2 (DBP2).
- Trial name
- NCT07468188
- Testing
- Body Project Type 2
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Joslin Diabetes Center
Diabetes Mellitus, Percutaneous Coronary Intervention
Correlation Between Targeted HbA1c Values and Prevention of Recurrent Cardiovascular Events in Type 2 Diabetes After PCI
Diabetes is a leading social and economic burden in the world. It is the main reason of macrovascular disease incidence and mortality.
- Trial name
- CATHEDRAL (NCT05134129)
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Shanghai 10th People's Hospital
Gestational Diabetes, Gestational Diabetes Mellitus in Pregnancy
Clinic to Community Connections - Broader Distribution
This study addresses education needs in gestational diabetes care and followup at the staff and patient levels. In the initial phase, nurses and community health workers will complete specific training modules on gestational…
- Trial name
- NCT04474795
- Testing
- Staff -Educational training
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Type 2 Diabetes, Healthy Lifestyle Behaviors
Harnessing Human Potential and Improving Health Span in Women and Their Children
Women with Gestational Diabetes Mellitus (GDM) are 12-times more likely to develop Type 2 Diabetes (T2D) 4-6 years after delivery than women without GDM.
- Conditions
- Type 2 Diabetes, Healthy Lifestyle Behaviors, Gestational Diabetes
- Trial name
- HAPPY (NCT05949957)
- Testing
- LvL UP App, HAPPY App, Oura Ring And Oura App
- Where
- Singapore
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Heart Failure, Diabetes Mellitus, Type 2
Electronic Alerts for Heart Failure Prevention in Diabetes
Type 2 diabetes mellitus (T2DM) is an independent risk factor for heart failure (HF) and is associated with significant morbidity and mortality.
- Trial name
- NCT04791826
- Testing
- On-screen electronic alert
- Where
- United States
- Volunteers
- 1,524 people
- Sponsor
- University of Texas Southwestern Medical Center