Clinical trials: Type 2 Diabetes Risk
Type 2 Diabetes Mellitus (T2DM), Hypertension
Eating Window and Sleep Disorders on Glycemic Control, Cardiovascular Risk, and Weight Loss
This project aims to offer a quantitative and qualitative nutritional approach, along with educational nutritional guidelines for participants with Non-Communicable Chronic Diseases.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Hypertension, Obesity and Type 2 Diabetes, Cardiovascular Diseases
- Trial name
- NCT06735859
- Testing
- Comparison of eating windows intervention
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
Pre-diabetes, Pre-diabetic State
VA|PREVENTION: Randomized Controlled Trial of a Person-Centred Digital Intervention to Prevent Diabetes in High-Risk Adults
The goal of this clinical trial is to help prevent the development of type 2 diabetes (T2D) in adults who are at risk. The study will test a digital intervention called VA|PREVENTION, a web application designed to support and…
- Trial name
- VA|PREVENTION (NCT07021144)
- Testing
- VA|PREVENTION web application (digital intervention), Type 2 Diabetes Guidebook
- Where
- 16 sites in Portugal
- Volunteers
- 180 people
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Type 1 Diabetes (T1D), Type 2 Diabetes (T2DM)
"Sexual Activity and Hypoglycemia Risk in Adults With Type 1 or Type 2 Diabetes Using Insulin Therapy and Continuous Glucose Monitoring"
This observational study examines whether sexual activity influences the risk of hypoglycemia in adults with type 1 or type 2 diabetes treated with insulin therapy and using continuous glucose monitoring (CGM).
- Conditions
- Type 1 Diabetes (T1D), Type 2 Diabetes (T2DM), Hypoglycemia
- Trial name
- SEX-HYPO-CGM (NCT07286500)
- Testing
- No intervention
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Warsaw
Gestational Diabetes
Pedometers for Gestational Diabetes
Ten to 50% of women with gestational diabetes (GDM), or glucose intolerance first recognized during pregnancy, develop diabetes within 5 years after delivery.
- Trial name
- PEG (NCT00862602)
- Testing
- Stepping Up to Health
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan
Type 2 Diabetes, Cardiovascular Risk
Canagliflozin and Myocardial Fibrosis
Recently, large clinical intervention studies have demonstrated the cardiovascular protective effects on of sodium-glucose cotransporter 2 inhibitors (SGLT2i) such as empagliflozin, dapagliflozin, and canagliflozin in reduction…
- Trial name
- CANA-DIA-FIB (NCT05367063)
- Testing
- Canagliflozin 100mg or Sitagliptin 100mg
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Shanghai Zhongshan Hospital
Gestational Diabetes Mellitus, Pre-diabetes
Encourage Healthy Families
This study is a randomized intervention that will test two different approaches reflecting diverse levels of both intensity and cost, to achieving risk reduction of T2D.
- Trial name
- Encourage (NCT01823367)
- Testing
- Diabetes Prevention Program (DPP)
- Where
- United States
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- Indiana University
Diabetes, Gestational, Diabetes Mellitus, Type 2
Study to Understand Risk Information to Support and Empower
The aim of this trial is to test components of a digital health outreach intervention to promote uptake of postpartum screening and lifestyle programs for diabetes prevention among patients with gestational diabetes (GDM).
- Trial name
- SUNRISE (NCT05752292)
- Testing
- Standard Health Information, Values Affirmation (VA), Tailored Risk Information (TRI)
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- University of California, Davis
Coronary Heart Disease, Type 2 Diabetes
Coronary Heart Disease Risk in Type 2 Diabetes
The primary objective of the CORDIA study is to use an effective evidence-based self-management intervention (SMI) for type 2 diabetes, with and without a novel test to give a personalised genetic and lifestyle risk of coronary…
- Trial name
- CORDIA (NCT01891786)
- Testing
- Self-Management Intervention, Risk Result
- Where
- 10 sites in United Kingdom
- Volunteers
- 211 people
- Sponsor
- City, University of London
Obstructive Sleep Apnea, Diabetes Mellitus
Assessing the Risk of Developing Type II Diabetes Using Serum Biomarkers in Patients Diagnosed With Obstructive Sleep Apnea
The investigators plan to recruit 140 patients (35 subjects in each group) over a period of 18 months in a prospective study of matched/paired case-control subjects across the four groups to measure the 5-year risk of developing…
- Trial name
- OSA & DM (NCT01447251)
- Testing
- PreDx Diabetes Risk Score
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mike O'Callaghan Military Hospital
Prediabetic State, Diabetes type2
Effect of Totum-63 on Glucose and Lipid Homeostasis in Subjects With Dysglycemia (REVERSE-IT)
This clinical study aims to assess the efficacy of TOTUM-63, a mix of 5 plant extracts, consumed at the daily regimen of three times per day on glucose and lipid homeostasis in dysglycemic subjects.
- Conditions
- Prediabetic State, Diabetes type2, Dysglycemia
- Trial name
- REVERSE-IT (NCT04423302)
- Testing
- TOTUM-63 3 intakes per day, TOTUM-63 2 intakes per day
- Where
- 52 sites in Bulgaria, France and 5 more
- Volunteers
- 636 people, healthy volunteers welcome
- Sponsor
- Valbiotis
Type II Diabetes Mellitus, Obesity
A Study Evaluating the Effects of a High Viscosity Non-starch Polysaccharide (PolyGlycopleX® - PGX®) on Glycemic Control, Cardiometabolic Risk Factors and Weight Loss in Overweight and Obese Type II Diabetics
One out of two adults in Canada is currently overweight and therefore at increased risk for a number of medical conditions including diabetes, high blood pressure, heart attacks and stroke.
- Trial name
- NCT01644201
- Testing
- PolyGlycopleX® - PGX®
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- InovoBiologic Inc.
Carbohydrate, Hypoxia
Isolated and Combined Effect of a Low Carbohydrate Diet and Exercise in Hypoxia in Patients With Type 2 Diabetes
The purpose of this study is to determine the effects of isolated chronic exercise in hypoxia and combined exercise in hypoxia with a low carbohydrate diet on hypoxia-induced transcription factor (HIF1-α); glycaemic control and…
- Conditions
- Carbohydrate, Hypoxia, Exercise, Diabetes Mellitus, Type 2
- Trial name
- NCT05094505
- Testing
- Exercise in normoxia, Control diet, Exercise in hypoxia
- Where
- 2 sites in Portugal
- Volunteers
- 42 people
- Sponsor
- Universidade do Porto
Type 2 Diabetes, Insulin Resistance
The Effects of Two Days of Bedrest on Insulin Resistance in Type 2 Diabetics
The hypothesis of this study is that bed rest in diabetic patients will result in a deterioration of metabolic control (primarily glucose). Specific aims: 1.
- Trial name
- NCT00508599
- Testing
- Study 2 (48 hours of complete bed rest)
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Cardiovascular Diseases, Diabetes Mellitus, Type 2
High Risk Population of Cardiovascular Disease in Hubei Province Screening and Intervention Program
High Risk Population of Cardiovascular Disease in Hubei Province (Coronary Heart Disease With Diabetes) Screening and Intervention Program（CCDInT）is a randomized controlled study to verify that protocol treatment group is more…
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Type 2, Coronary Disease
- Trial name
- NCT05782881
- Testing
- phone calls and encouraging patients' lifestyle change and medication adherence, Statin
- Where
- 107 sites in China
- Volunteers
- 16,000 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Diabetes Mellitus, Type 2, Hypertension
The Effect of Progressive Resistance Exercise Training (PRET) on CVRF in Adults With ID.
Thanks to improved healthcare, the life expectancy of people with ID is increasing and is approaching that of the general population.
- Conditions
- Diabetes Mellitus, Type 2, Hypertension, Hypercholesterolemia, Obesity
- Trial name
- PRET (NCT06579898)
- Testing
- Progressive resistance exercise training
- Where
- 3 sites in Netherlands
- Volunteers
- 36 people
- Sponsor
- Erasmus Medical Center
Caries,Dental, Caries Root
Coronal and Radicular Caries Prevalence and Related Risk Factor in Diabetic Patient
This study aims to investigate the prevalence and risk factors of coronal and radicular caries in middle-aged individuals with Type 2 diabetes.
- Conditions
- Caries,Dental, Caries Root, Diabetes Mellitus, Type 2
- Trial name
- NCT06701565
- Volunteers
- 265 people
- Sponsor
- Cairo University
Depression, Impaired Glucose Tolerance
Mood and Insulin Resistance in Adolescents At-Risk for Diabetes
Background: Type 2 diabetes is a chronic disease that puts individuals at risk for serious health problems like heart disease, kidney failure, vision problems, and stroke.
- Trial name
- NCT01425905
- Testing
- The Blues Program, Hey Durham
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Type 2 Diabetes Mellitus, Hypercholesterolemia
Atorvastatin, Aspirin, Oxidative Stress, Coagulation and Platelet Activation Indexes
Primary and secondary prevention trials with statins, as well as with antiplatelet, clearly demonstrated that these drugs are able to reduce cardiovascular events.
- Trial name
- NCT01322711
- Testing
- Atorvastatin
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Roma La Sapienza
At Risk of Type 2 Diabetes Mellitus
Acute Effect of MMT Peel Powder on Glycemic Response, Satiety, and Food Intake in Adults at Risk for Type 2 Diabetes
Open-label, randomised, placebo-controlled, crossover study with two intervention arms. The study was conducted in 30 respondents and the primary objective is to show an improved glycemic response after Melon Manis Terengganu…
- Trial name
- NCT05298111
- Testing
- Formulation 3, Control
- Where
- Malaysia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universiti Sultan Zainal Abidin
Insulin Resistance
Evaluation of the Impact of a Nutritional Supplement Made of Vegetable Oils in People at Risk of Diabetes
Metabolic and cardiovascular diseases are the first cause of morbidity and mortality throughout the world, including Latin America and Colombia.
- Trial name
- NCT03512665
- Testing
- Full dose supplement, Low dose Supplement, Control Oil
- Where
- Colombia
- Volunteers
- 25 people
- Sponsor
- University of Los Andes, Columbia