Clinical trials: Type 2 Diabetic Kidney Disease
Kidney Transplant, Diabetes Mellitus, Type 2
Immunosuppression Impact on the Metabolic Control of Kidney Transplant With Pre-Existing Type 2 Diabetes (DM)
Protocol Title: Randomized open label study comparing the metabolic control of first Kidney Transplant recipients with Type 2 Diabetes Mellitus (DM) receiving either Prograf or Neoral as part of a ATG induction, prednisone free…
- Conditions
- Kidney Transplant, Diabetes Mellitus, Type 2, Diabetic Nephropathy
- Trial name
- NCT00296296
- Testing
- Cyclosporin, Tacrolimus, 'Diabetes Education / Management'
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Stanford University
Type 2 Diabetes, Diabetic Nephropathy
Pioglitazone and Losartan Provides Additional Renoprotection
Peroxisomal proliferator-activated receptor agonist pioglitazone and rosiglitazone are currently used in the treatment of type 2 diabetes, as efficient insulin sensitizers alone or in combination with insulin.angiotensin II…
- Trial name
- NCT00364988
- Testing
- pioglitazone+losartan, losartan
- Volunteers
- 60 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Diabetic Nephropathy
Adiponectin and Insulin Resistance in Diabetic Nephropathy
Plasma adiponectin concentration is inversely associated with renal function. There is little literature on adiponectin levels and regulation by antihypertensive medication with an angiotensin II-receptor blocker (ARB)…
- Trial name
- NCT00774904
- Testing
- Losartan
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xi'an Jiaotong University
Type 2 Diabetes With Renal Manifestations
Clinical Study of Umbilical Cord Mesenchymal Stem Cells in the Treatment of Type 2 Diabetic Nephropathy
The study was a 48-week multicenter, randomized, double-blind, placebo-controlled trial that included 8 weeks of pre-screening and lifestyle education, 32 weeks of treatment, and 16 weeks of follow-up.To observe the efficacy and…
- Trial name
- NCT04216849
- Testing
- human umbilical cord mesenchymal stem cells, saline
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Shanghai East Hospital
Type 2 Diabetes, Cardiovascular Complication
Effects and Safety of Diabetic GUideline Algorithm Implementation Performed by Primary Care Physicians in the Community
The Effects and Safety of Diabetic GUideline Algorithm Implementation in the Community (GUARD-Community) study is a 2-arm, cluster-randomized control trial to evaluate the effect and safety of guideline algorithm intervention…
- Conditions
- Type 2 Diabetes, Cardiovascular Complication, Diabetic Kidney Disease
- Trial name
- GUARD (NCT05349955)
- Testing
- Intensive guideline algorithm implementation, Conventional guideline algorithm implementation
- Where
- 13 sites in China
- Volunteers
- 5,600 people
- Sponsor
- Shanghai Zhongshan Hospital
Obese Type 2 Diabetic Patients
Modified Atkins Diet and Type 2 Diabetic Patients
This randomized control trial compared the influence of an Atkins diet to that of the ADA recommended diet on Type 2 diabetic obese patients during a one-year follow-up period
- Trial name
- NCT00552890
- Testing
- modified Atkins diet, ADA recommended diet
- Volunteers
- 52 people
- Sponsor
- Hadassah Medical Organization
Diabetic Nephropathy Type 2
the Integrated Traditional Chinese and Western Medicine Treat Middle Stage DKD
Efficacy and Safety of treatment with Traditional Chinese Medicine ShenqiDihuang Decoctions in Patients with middle stage of Diabetic Kidney Disease.
- Trial name
- NCT03681249
- Testing
- ShenqiDihuang Decoction
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Diabetic Nephropathy
Safety and Efficacy of Aliskiren When Added to Standardized Losartan and Optimal Antihypertensive Therapy in Patients With Hypertension, Type 2 Diabetes and Proteinuria
Study of the efficacy and safety of aliskiren when added to losartan and optimal antihypertensive therapy in patients with hypertension, type 2 diabetes, and kidney disorders to monitor improvement in any of these conditions.
- Trial name
- NCT00097955
- Testing
- aliskiren
- Where
- 12 sites in United States, Canada and 10 more
- Volunteers
- 496 people
- Sponsor
- Novartis Pharmaceuticals
Diabetic Kidney Disease, Diabetes Mellitus, Type 2
EMPRA (EMPagliflozin and RAs in Kidney Disease)
This study will be a prospective, clinical pilot study in CKD patients to show whether Empagliflozin in addition to ACEi treatment significantly increases Ang 1-7 levels compared to ACEi treatment alone.
- Conditions
- Diabetic Kidney Disease, Diabetes Mellitus, Type 2, Chronic Kidney Disease stage3, Chronic Kidney Disease stage4
- Trial name
- EMPRA (NCT03078101)
- Testing
- Empagliflozin 10 MG [Jardiance]
- Where
- Austria
- Volunteers
- 51 people
- Sponsor
- Medical University of Vienna
Diabetes Mellitus, Diet
LoBAG30 Diet in Patients on Metformin
We will determine the metabolic response to a Low Biologically Available Glucose Diet (LoBAG30) in subjects currently receiving the maximum dose of metformin as monotherapy in whom the glycohemoglobin is not at an acceptable…
- Trial name
- LoBAG Diet (NCT00607867)
- Testing
- LoBAG30 diet, Control Diet
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- US Department of Veterans Affairs
Type2 Diabetes Mellitus
Heart Rate Variability and Diabetic Kidney Disease in Type 2 Diabetes Mellitus Patients
Several studies have investigated an association between cardiac autonomic neuropathy (CAN) and albuminuria, glomerular filtration rate, or both, and hypothesized that CAN is involved in the pathogenesis of nephropathy.
- Trial name
- NCT02996539
- Testing
- Clinical examination and laboratory measurements
- Where
- China
- Volunteers
- 392 people
- Sponsor
- Shi wei, MM
Type 2 Diabetes Mellitus With Diabetic Nephropathy
Serum 1,25-dihydroxyvitamin D Levels in Type 2 Diabetes Mellitus Patients With Different Levels of Albuminuria
Diabetic nephropathy(DN)is a major microvascular complication of diabetes.Renal injury may be presented with the characteristics of albuminuria, and its main pathological change is glomerular sclerosis.
- Trial name
- DM (NCT01845870)
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Tianjin Medical University General Hospital
Diabetic Foot, Type 2 Diabetes Mellitus With Established Diabetic Nephropathy
The Effectiveness of Improving Self-care After Counseling for the Diabetics Mellitus Foots Around Chiayi Region
Objectives: Preventing diabetic foot problems (DFP) and associated consequences, such as amputation, is a critical in rural regions.
- Trial name
- NCT01299246
- Testing
- Michigan Neuropathy Screening Instrument
- Where
- Taiwan
- Volunteers
- 386 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Diabetic Kidney Disease
Non Diabetic Causes of Chronic Kidney Disease in Type 2 Diabetic Patients
Determination of the possible causes of chronic kidney disease (CKD) in patients with type 2 diabetes mellitus with an atypical presentations of renal disease for proper management and thus improving renal outcome.
- Trial name
- NCT05021705
- Volunteers
- 60 people
- Sponsor
- Assiut University
Diabetes Mellitus Type 2
Effects of High-Resistance Inspiratory Muscle Strength Training on Cardiorenal and Vascular Function in Youth and Young Adults With Type 2 Diabetes
High-resistance, short-duration inspiratory muscle strength training (IMST) is a novel lifestyle intervention involving 30 inhalations against a resistive load which requires only ~5 min/day and is thus ideal for youth with T2D…
- Trial name
- IMST (NCT06936670)
- Testing
- Inspiratory Muscle Strength Training (IMST)
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Seattle Children's Hospital
Type 2 Diabetes Mellitus
Measurement of Eye Blood Flow and Renal Function in Healthy and Diabetic Patients
The purpose of this study is to the determine the effect of salt intake and Captopril on the ophthalmic artery (OA) blood supply of individuals with Type 2 Diabetes Mellitus.
- Trial name
- NCT01626469
- Testing
- Captopril
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Brigham and Women's Hospital
Diabetic Nephropathies
Relation Between Plasma Apelin Level and Diabetic Nephropathy in Type 2 Diabetes Patients.
Diabetic nephropathy (DN) is the commonest cause of chronic kidney disease, and proteinuria isn't determent factor for the end stage renal disease in diabetics.
- Trial name
- NCT04380584
- Testing
- plasma Apelin level
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Diabetic Kidney Disease (DKD)
Autologous Dendritic Cell as Adjunct Therapy for Diabetic Kidney Disease
The goal of this single-arm, open-label clinical trial is to evaluate the effects of subcutaneous autologous dendritic cell (DC) and lymphocyte administration on albuminuria and endothelial dysfunction in Type 2 Diabetes Mellitus…
- Trial name
- NCT06866158
- Testing
- Dendritic cell immunotherapy
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- PT. JES Kasih Nusantara Sejahterah
Type 2 DM /Diabetic Nephropathy
CRP to Serum Albumin Ratio in Type 2 DM é Diabetic Nephropathy
we aimed to compare C-reactive protein to serum albumin ( CAR) level of the T2DM patients with DN to those T2DM without DN
- Trial name
- NCT05681286
- Volunteers
- 70 people
- Sponsor
- Assiut University
Diabetes Mellitus, Type 2
Safety and Efficacy in Type 2 Diabetic Patients With Severe Chronic Renal Impairment, 5 mg BI 1356 (Linagliptin) vs. Placebo, Insulin Background Inclusive
to determine safety, efficacy and tolerability of BI 1356 versus placebo
- Trial name
- NCT00800683
- Testing
- BI 1356
- Where
- 53 sites in United States, Australia and 4 more
- Volunteers
- 133 people
- Sponsor
- Boehringer Ingelheim