Clinical trials: Type A Botulinum Toxin
Ecchymosis After Periorbital Rejuvenation With Botulinum Toxin Type A, Crow's Feet Lines
A Real-World Study on Effect of Hirudoid on Ecchymosis After Treatment of Crow's Feet With Botulinum Toxin Type A
Botulinum toxin type A (commonly referred to as 'Botox') injections are a treatment that dermatologists regularly use to smoothen wrinkles such as 'Crow's feet', to rejuvenate the skin surrounding the eye (the 'periorbital…
- Conditions
- Ecchymosis After Periorbital Rejuvenation With Botulinum Toxin Type A, Crow's Feet Lines, Lateral Canthal Lines, LCL
- Trial name
- NCT07388927
- Testing
- Hirudoid (heparinoids) ointment, 3mg/g
- Volunteers
- 48 people
- Sponsor
- DKSH Management (Thailand) Limited
Postherpetic Neuralgia
A Study Evaluating Botulinum Toxin Type A in Subjects With Postherpetic Neuralgia
4-month study including a 30-day baseline phase
- Trial name
- NCT00168441
- Testing
- Botulinum Toxin Type A
- Volunteers
- 117 people
- Sponsor
- Allergan
Spasticity
ETREAT Study on Effectiveness of Botulinum Toxin Type A Injections to Treat Post-stroke Upper and/or Lower Limb Spasticity
The objective of this study is to evaluate the effectiveness of BoNT-A on functional improvement in patients with post-stroke upper and/or lower limb spasticity in the early stage of spasticity development, according to routine…
- Trial name
- ETREAT (NCT02275312)
- Where
- 17 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Ipsen
Restless Legs Syndrome
Restless Legs Syndrome Treatment With Botulinum Toxin
Restless Legs Syndrome (RLS) is a common sensori-motor disorder that causes sensory discomfort and motor restlessness, most often in the legs, which improves with movement.
- Trial name
- SOXIS (NCT00949806)
- Testing
- BNT (intradermal injection)
- Where
- France
- Volunteers
- 27 people
- Sponsor
- University Hospital, Bordeaux
Spasticity
Study Assessing Adult Subjects Affected With Upper and/or Lower Limb Spasticity Treated With Botulinum Neurotoxin Type A
The aim of the study is to describe the long term use of Botulinum Neurotoxin Type A (BoNT-A) in adult subjects affected with upper and/or lower limb spasticity who received treatment with BoNT-A for a minimum of three injections…
- Trial name
- RESULT (NCT04340336)
- Where
- 3 sites in Italy
- Volunteers
- 150 people
- Sponsor
- Ipsen
Cerebral Palsy, Muscle Spasticity
Does Botulinum Toxin A Make Walking Easier in Children With Cerebral Palsy?
In Norway, about 60% of all children with cerebral palsy (CP) are being treated with botulinum toxin A (BoNT-A) at 6 years of age, mainly in the legs.
- Trial name
- WE (NCT02546999)
- Testing
- botox
- Where
- 7 sites in France, Norway and 1 more
- Volunteers
- 61 people
- Sponsor
- St. Olavs Hospital
Lower Limb Spasticity Due to Cerebral Palsy
Dose-response Study of Efficacy and Safety of Botulinum Toxin Type A to Treat Spasticity of the Leg(s) in Cerebral Palsy
The purpose of this study is to determine whether injections of Botulinum toxin type A into muscles of the leg(s) are effective in treating children/adolescents (age 2-17 years) with increased muscle tension/uncontrollable muscle…
- Trial name
- NCT01893411
- Testing
- IncobotulinumtoxinA (16 Units per kg body weight), IncobotulinumtoxinA (12 Units per kg body weight), IncobotulinumtoxinA (4 Units per kg body weight)
- Where
- 53 sites in Austria, Czechia and 12 more
- Volunteers
- 311 people
- Sponsor
- Merz Pharmaceuticals GmbH
Androgenetic Alopecia (AGA)
PRP Combined With Botulinum Toxin Type A Injection for the Treatment of Androgenetic Alopecia: A Study
Research Purpose The objective of this study is to determine the safety and efficacy of combined PRP and BTX-A injection therapy for Androgenetic Alopecia (AGA).
- Trial name
- AGA (NCT07335367)
- Testing
- Injection of PRP combined with Botulinum Toxin Type A into the alopecic area(s), PRP-only injection into the alopecic area
- Where
- China
- Volunteers
- 83 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Patellofemoral Pain Syndrome
Botox for Non-surgical Lateral Release in Patellofemoral Pain
The purpose of this study is to determine whether the use of botulinum toxin A injected into the lateral thigh muscle improves knee function and reduces knee pain secondary to patellofemoral syndrome.
- Trial name
- NCT00496964
- Testing
- Botulinum toxin A + exercise
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Virginia Commonwealth University
Migraine Without Aura Prophylaxis
Dysport® In Migraine Without Aura Prophylaxis : DIMWAP Study
The purpose of this study is to determine whether 120 Unit, and 240 unit of botulinum toxin A are effective in the treatment of migraine without aura prophylaxis.
- Trial name
- NCT00258609
- Testing
- Botulinum Toxin type A (Dysport ® ) IM/SC 6-sites pericranial injection
- Where
- 6 sites in Thailand
- Volunteers
- 128 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Lateral Canthal Lines
Safety and Efficacy Study of RT001 to Treat Moderate to Severe Lateral Canthal Lines
The purpose of this study is to evaluate the safety and efficacy of RT001 to treat moderate to severe lateral canthal lines in adults and duration of effect.
- Trial name
- NCT00907387
- Testing
- RT001
- Where
- 9 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Revance Therapeutics, Inc.
Neuralgia
Botulinum Toxin Type A for Neuropathic Pain in Patients With Diabetic Peripheral Polyneuropathy
The purpose of this study is to determine whether botulinum toxin A is effective in the treatment of neuropathic pain in patients with diabetic peripheral polyneuropathy.
- Trial name
- BTXADMPPNP (NCT02460107)
- Testing
- Botulinum toxin type A, Normal saline
- Where
- South Korea
- Volunteers
- 9 people
- Sponsor
- Catholic University of Korea Saint Paul's Hospital
Hemiparesis After Stroke, Traumatic Brain Injury
Partial Blocks of Rectus Femoris and Soleus With Botulinum Toxin Type A (Xeomin®) to Improve Gait in Hemiparesis
The most common motor deficiency after stroke or traumatic brain injury is hemiparesis. Most hemiparetic patients recover walking, but rarely with a speed permitting easy ambulation outdoors with family or friends.
- Trial name
- GENUFLEX (NCT03119948)
- Testing
- Botulinum toxin injection
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Overactive Bladder
A Long-term Follow-up Study of Botulinum Toxin Type A in Patients With Overactive Bladder as a Result of Spinal Injury or Multiple Sclerosis
The purpose of this study is to assess the long-term safety and effectiveness of botulinum toxin type A on patients with overactive bladder as a result of spinal cord injury or multiple sclerosis.
- Trial name
- NCT00876447
- Testing
- Botulinum Toxin Type A 300U, Botulinum Toxin Type A 200U
- Where
- 22 sites in United States, Australia and 20 more
- Volunteers
- 397 people
- Sponsor
- Allergan
Smiling, Botulinum Toxins, Type A
Application of Botulinum Toxin at the Yonsei Point for the Treatment of Gummy Smile
The purpose of the present study will be to evaluate the efficacy of a single dose of botulinum toxin (BTX) at the Yonsei point for the treatment of gummy smile (GS).
- Trial name
- NCT04527744
- Testing
- the injection of onabotulinumtoxinA at different point
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Peking University
Buerger Disease, Raynaud Syndrome
Evaluation of Botulinum TOXin Type A in the Treatment of Buerger's Disease
The main objective is to assess the feasibility of treatment by injecting botulinum toxin A into the hand or foot of patients with signs of critical ischemia secondary to Buerger's disease.
- Trial name
- BETOX (NCT05698979)
- Testing
- BOTOX INJECTION
- Where
- France
- Volunteers
- 8 people
- Sponsor
- University Hospital, Toulouse
Prostate Cancer, Benign Prostatic Hyperplasia
BOTOX in Men With Prostate Cancer With Lower Urinary Tract Symptoms(LUTS)/Benign Prostatic Hyperplasia (BPH)
This is a pilot study examining biological endpoints in men with localized prostate cancer who are scheduled to have radical prostatectomies and men with Benign Prostatic Hyperplasia/Lower Urinary Tract Symptoms (BPH/LUTS)…
- Conditions
- Prostate Cancer, Benign Prostatic Hyperplasia, Enlarged Prostate With Lower Urinary Tract Symptoms (LUTS)
- Trial name
- NCT01520441
- Testing
- BOTOX
- Where
- United States
- Sponsor
- The University of Texas Health Science Center, Houston
Multiple Sclerosis, Tremor
The Efficacy of Botulinum Toxin in Disabling Multiple Sclerosis (MS) Tremor
The incidence of tremor in Multiple Sclerosis (MS) has been estimated to affect up to 2/3rds of patients. Over half of the tremors involve the upper limb and frequently lead to further disability.
- Trial name
- NCT01018485
- Testing
- Botulinum Toxin Type A
- Where
- Australia
- Volunteers
- 30 people
- Sponsor
- Melbourne Health