Clinical trials: Type I Diabetes Mellitus
Diabetes
Improved Glycemic Control in Adult Subjects With Type 1 Diabetes on MDI Using Insulin Guidance Software
140 subjects will be enrolled into the clinical study and randomized into the Control Group or the Experimental Group by block randomization. The subjects must meet all inclusion and none of the exclusion criteria.
- Trial name
- NCT00552734
- Testing
- Insulin Guidance Software
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- University of Colorado, Denver
Type 1 Diabetes (T1D), Nutrition Therapy
Meal Frequency and Glycemic Control in Individuals With Type 1 Diabetes
The goal of this clinical trial is to examine the effect of 3 versus 6 daily meals of isocaloric diets on glycemic control and variability in individuals with type 1 diabetes.
- Conditions
- Type 1 Diabetes (T1D), Nutrition Therapy, Glycemic Control for Diabetes Mellitus
- Trial name
- NCT06934707
- Testing
- Three meals a day, Six meals a day
- Where
- Brazil
- Volunteers
- 27 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
Continuous Glucose Metrics in Patients With Gastroparesis in Type 1 or Type 2 Diabetes
A pilot study to evaluate and compare glucose metrics using a real-time continuous glucose monitor (FreeStyle Libre 3 sensor) between patients with diabetes and gastroparesis and those with diabetes without gastroparesis.
- Conditions
- Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Gastroparesis With Diabetes Mellitus
- Trial name
- NCT06046833
- Testing
- FreeStyle Libre 3 continuous glucose monitoring sensor, Nutritional drink
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Samita Garg
Type 1 Diabetes
The Effect of Improved Glycemic Control on the Composition and Function of High-Density Lipoproteins (HDL) in Patients With Type 1 Diabetes
The HAGI-T1D study aims to determine the effect of improved glycemic control on the composition and function of high-density lipoproteins (HDL) in patients with type 1 diabetes (T1D).
- Trial name
- HAGI-T1D (NCT07564752)
- Testing
- Blood test, Urine sample
- Where
- France
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Type 1 Diabetes Mellitus
Intraperitoneal vs Subcutaneous Insulin Administration in Type 1 Diabetes Mellitus
Almost all patients with type 1 diabetes mellitus (T1DM) need insulin treatment permanently. For selected patients who are unable to achieve glycaemic targets with subcutaneous (SC) insulin treatment, continuous intraperitoneal…
- Trial name
- IPvsSC (NCT01621308)
- Testing
- Mode of insulin administration
- Where
- 2 sites in Netherlands
- Volunteers
- 190 people
- Sponsor
- Medical Research Foundation, The Netherlands
Type 1 Diabetes
Effectiveness of a Multidisciplinary Treatment and Structured Education Programme
This trial compared an structured education programme and multidisciplinary treatment vs an standard treatment in type 1 diabetes patient, the Primary outcome is glycemic control at 6-month follow up and secondary outcome are…
- Trial name
- NCT06184815
- Testing
- Educational programme 12, Standard education and treatment
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Diabetes Mellitus, Insulin-Dependent, Diabetes
The RADAR Study - Wearable-Based Dysglycemia Detection and Warning in Diabetes
The study RADAR aims at developing a wearable based dysglycemia detection and warning system for patients with diabetes mellitus using artificial intelligence.
- Trial name
- RADAR (NCT04689685)
- Testing
- Wearing smartwatch and continous glucose sensor
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Type 1 Diabetes Mellitus
Study to Find Out if Intensive Diabetes Clinic and Continuous Glucose Monitors Help Teenagers With Diabetes
The purpose of this research study is to find out ways to help pre-teens and teens and their families to improve diabetes control and to help with the burden of diabetes management.
- Trial name
- NCT01083433
- Testing
- Diabetes related psychological counseling and education, Continuous Glucose Monitor
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University Hospitals Cleveland Medical Center
Type 1 Diabetes Mellitus, Insulin Pump
Evaluating an Insulin Pump for Time in Range (TIR) in Patients with Type 1 Diabetes
Diabetes mellitus is a metabolic disorder caused by genetic, environmental changes, mental health issues, immune disorders, and other factors.
- Conditions
- Type 1 Diabetes Mellitus, Insulin Pump, Time in Range
- Trial name
- NCT06741943
- Testing
- insulin pump (model: AR-B200A)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Tao Yuan,MD
Type 1 Diabetes
Beta Cell Function in (Pre) Type 1 Diabetes
This study will establish criteria indicating short-term loss of beta cell mass and therefore accelerated progression towards type 1 diabetes.
- Trial name
- NCT00800085
- Testing
- glucose 20%
- Where
- 4 sites in Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Type1 Diabetes Mellitus, Diabetes Mellitus, Type 1
MEtabolic and Renal Effects of AutoMAted Insulin Delivery Systems in Youth With Type 1 Diabetes Mellitus
In type 1 diabetes (T1DM), automated insulin delivery (AID) systems such as the hybrid closed loop artificial pancreas (HCL AP) combine the use of an insulin pump, continuous blood sugar monitor, and control algorithm to adjust…
- Conditions
- Type1 Diabetes Mellitus, Diabetes Mellitus, Type 1, Autoimmune Diabetes, Juvenile Diabetes
- Trial name
- MERMAID-T1D (NCT03945747)
- Testing
- Blood draw, Urine sample collection, DXA scan
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Diabetes, Diabetes (Insulin-requiring, Type 1 or Type 2)
Diabetes and Permanent Disabilities
This study examines permanent disability related to diabetes using routinely collected data from the National Insurance Institute of Israel.
- Trial name
- DIAB-PD (NCT07788235)
- Where
- 2 sites in Israel
- Volunteers
- 450,000 people
- Sponsor
- Assuta Medical Center
Diabetes Mellitus Type 2, Diabetes Mellitus Type 1
SMARTCLOTH. Design, Implementation and Study of the Effectiveness and Usability of a Digital Tablecloth for Self-management of Diet in Diabetic Patients.
The objective of this clinical trial is to know the usability and efficacy of SMARTCLOTH for better control and adherence to the dietary patterns recommended to patients with diabetes, both the portion diet system (more common…
- Trial name
- NCT06623708
- Testing
- SMARTCLOTH
- Where
- 5 sites in Spain
- Volunteers
- 90 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Diabetes Mellitus, Type 1
Counter-Regulatory Impairment and the Effect of Microvascular Insulin Transfer in Type 1 Diabetes Mellitus
The researchers plan to test the following hypothesis: A good level of glucose control in Type 1 Diabetes Mellitus (T1DM) is dependent on two levels of feedback from the body: 1.
- Trial name
- BPK003 (NCT00943787)
- Testing
- Hyperinsulinemic, euglycemic and hypoglycemic clamp
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Virginia
Type 1 Diabetes
Efficacy and Safety of Sorafenib in New-Onset Type 1 Diabetes Mellitus
The purpose of this study is to investigate the therapeutic effect and safety of Sorafenib in T1DM patients.
- Trial name
- NCT06227221
- Testing
- Sorafenib
- Volunteers
- 10 people
- Sponsor
- Second Xiangya Hospital of Central South University
Type1 Diabetes Mellitus
Evaluation of the Effectiveness of a Program of Emotional Intelligence in Adolescents With Type 1 Diabetes (INTEDI)
Type 1 Diabetes Mellitus is one of the main health problems of the pediatric population worldwide, being one of the most frequent chronic endocrinology diseases in childhood and adolescence.
- Trial name
- INTEDI (NCT03734367)
- Testing
- Emotional abilities training program
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- Universidad Loyola Andalucia
Diabetes, Diabetes Mellitus, Type 1
Evaluation of Accuracy of Continuous Glucose Monitoring (CGM) in Patients With End Stage Renal Disease (ESRD) on Intermittent Hemodialysis (iHD).
Recent advances in continuous glucose monitors (CGMs) and availability of commercial CGM products to patients with type 1 and type 2 diabetes has made the use of CGM more widespread.
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- NCT04094064
- Testing
- Continuous Glucose Monitor
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Virginia
Type 2 Diabetes
A Study to Evaluate P-Glucose, Safety and Tolerability After Oral Single Dosing of AZD6370 in Type 2 Diabetic Patients
The purpose of this study is to assess the effect of AZD6370 on blood sugar and to study safety and tolerability in patients with type 2 diabetes.
- Trial name
- NCT00690287
- Testing
- AZD6370
- Where
- 3 sites in Sweden
- Volunteers
- 24 people
- Sponsor
- AstraZeneca
Type 1 Diabetes
Study of Insulin Therapy Augmented by Real Time Sensor IN Type 1 Children and Adolescents (START-IN!)
Glycemic control in children and adolescent with type 1 diabetes remains inadequate, exposing them to the risk of vascular complications in adulthood.
- Trial name
- START-IN (NCT00949221)
- Testing
- monitor Paradigm 754 VEO, MINILINK Real Time, Medtronic, CE
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Type 1 Diabetes Mellitus
Ovarian Ageing in Type 1 Diabetes Mellitus
In healthy women, early menopause is an event that is associated with the exacerbation of several risk factors of cardiovascular and skeletal disease.
- Trial name
- OVADIA (NCT01665716)
- Where
- Netherlands
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
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