Clinical trials: Type II Myocardial Infarction
Coronary Disease, Myocardial Infarction
Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures, Third Wave
The CLIMATE-III Observational Study examines to what extent chronically ill patients experience adverse health effects because of heat and whether the patients' specific health behavior, somatosensory amplification, risk and…
- Conditions
- Coronary Disease, Myocardial Infarction, Heart Failure, Arrhythmias, Cardiac
- Trial name
- CLIMATE-III (NCT06890208)
- Testing
- No intervention
- Where
- Germany
- Volunteers
- 176 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Type2 Diabetes, Antiplatelet Drugs
Type 2 Diabetes With Antiplatelet Drugs
Tabula Rasa HealthCare (TRHC), d/b/a CareKinesis, is the first national pharmacy that provides science-based medication risk identification and mitigation technologies and services.
- Conditions
- Type2 Diabetes, Antiplatelet Drugs, Myocardial Infarction, Heart Failure
- Trial name
- NCT05053828
- Testing
- Antiplatelet Drug
- Where
- United States
- Volunteers
- 173,464 people
- Sponsor
- Tabula Rasa HealthCare
Type 2 Diabetes Mellitus
Prediction of Findings From the Ongoing CAROLINA Trial Using Healthcare Database Analyses
This cohort study was initiated to predict the findings of CAROLINA trial in a real world setting using electronic claims data from insurance databases with results anticipated prior to the completion of CAROLINA.
- Trial name
- NCT03648424
- Where
- United States
- Volunteers
- 48,262 people
- Sponsor
- Brigham and Women's Hospital
Type 2 Diabetes, Cardiovascular Diseases
Effect of Liraglutide on the Metabolic Profile in Patients With Type 2 Diabetes and Cardiovascular Disease
In an unbiased metabolomics approach with subsequent pathway analyses, the current study seeks to examine the effect of Liraglutide treatment on the metabolic signature in treated patients as well as the effect of Liraglutide on…
- Trial name
- Lirabolic (NCT04057261)
- Testing
- Liraglutide Pen Injector [Victoza]
- Where
- Germany
- Sponsor
- RWTH Aachen University
Diabetic Patients, Acute Myocardial Infarction
Effect of Oral Semaglutide on Epicardial and Pericoronary Adipose Tissues in Type 2 Diabetes After Myocardial Infarction
The goal of this clinical trial is to investigate the ability of oral semaglutide to reduce pericardial and perivascular fat as well as coronary plaque in type 2 diabetic patients after acute myocardial infarction.
- Trial name
- SemaFatCard (NCT06557811)
- Testing
- Semaglutide
- Where
- Brazil
- Volunteers
- 88 people
- Sponsor
- University of Sao Paulo General Hospital
Diabetes Mellitus, Type 2, Myocardial Infarction
GLP-1RAs) and SGLT2is Combination Therapy and MACEs in Patients with Type 2 Diabetes.
Management of type 2 diabetes mellitus (T2DM) has evolved from a glucocentric to a cardiometabolic approach. Both glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter-2 inhibitors (SGLT2is) reduce…
- Trial name
- NCT06017544
- Testing
- PCI
- Where
- Italy
- Volunteers
- 257 people
- Sponsor
- University of Campania Luigi Vanvitelli
Cardiovascular Disease
Cardiovascular Inflammation Reduction Trial
The Cardiovascular Inflammation Reduction Trial (CIRT) is a randomized clinical trial investigating whether taking low-dose methotrexate reduces heart attacks, strokes, or death in people with type 2 diabetes or metabolic…
- Trial name
- CIRT (NCT01594333)
- Testing
- Methotrexate
- Where
- 470 sites in United States, Canada and 1 more
- Volunteers
- 4,786 people
- Sponsor
- Brigham and Women's Hospital
Type 2 Myocardial Infarction
Enhancing Cardiac Rehabilitation Attendance After Secondary Myocardial Infarction Through Clinician Messaging and Motivational Calls
The goal of this clinical trial is to determine if a behavioral intervention can increase attendance at cardiac rehabilitation (CR) after secondary/type 2 myocardial infarction in adult patients.
- Trial name
- ATTEND-CR (NCT07485491)
- Testing
- Clinician-level intervention, Patient-level intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Myocardial Infarction, Diabete Type 2
Effects of Dapagliflozin on Inflammatory Factorslevel and Prognosis in Type 2 Diabetes With Acute Myocardial Infarction
Dapagliflozin is one of the SGLT-2 inhibiters. Recent clinical trials have demonstrated that SGLT-2 inhibitors are effective for treating heart failure.
- Conditions
- Myocardial Infarction, Diabete Type 2, Glucose Intolerance
- Trial name
- NCT05050500
- Testing
- Dapagliflozin 10mg/Tab, control group
- Where
- China
- Volunteers
- 143 people
- Sponsor
- Qingdao Central Hospital
Diabetes Mellitus, Non-insulin Dependent, Cardiovascular Diseases
Heavy Metals, Obesity and Cardiovascular Risk - Ancillary to Look AHEAD
To evaluate the relationship of baseline toenail chromium concentrations to weight loss, as well as the interaction between heavy metals and the beneficial effects of weight loss.
- Conditions
- Diabetes Mellitus, Non-insulin Dependent, Cardiovascular Diseases, Obesity, Myocardial Infarction
- Trial name
- NCT00031213
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Colon Cancer, Lung Cancer
Predictive Genetic Risk Assessment Trial
This proof-of-principle clinical trial at Mayo Clinic studies how patients and their physicians understand and utilize predictive genetic risk assessment.
- Conditions
- Colon Cancer, Lung Cancer, Atrial Fibrillation, Diabetes Type 2
- Trial name
- PGT (NCT00782366)
- Testing
- SNP analysis
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Coronary Heart Disease, Acute Myocardial Infarction
Twenty-year Follow-up of the Inter99 Cohort
Being born small increases your risk of developing Type 2 diabetes (T2D) with age. Furthermore, data even suggest that some of the diseases ("complications") in the eyes, kidneys, nerves, liver, blood vessels and heart often seen…
- Conditions
- Coronary Heart Disease, Acute Myocardial Infarction, Cardiovascular Diseases, Type 2 Diabetes
- Trial name
- NCT05166447
- Where
- Denmark
- Volunteers
- 4,000 people
- Sponsor
- Bispebjerg Hospital
Myocardial Infarction
Effects of Bilberry and Oat Intake After Type 2 Diabetes and/or MI
Background: Bilberries from Sweden, rich in polyphenols, have shown cholesterol-lowering effects in small studies, and the cholesterol-lowering properties of oats, with abundant beta-glucans and potentially bioactive…
- Trial name
- BioDiaMI (NCT03620266)
- Testing
- Bilberry, Bioprocessed oat bran, Combination bilberry/oats
- Where
- 8 sites in Denmark, Sweden
- Volunteers
- 900 people
- Sponsor
- Ole Frobert, MD, PhD
Type 2 Diabetes, Acute Myocardial Infarction
Glucose Monitoring After Acute Myocardial Infarct in People With Diabetes
Glucose monitoring after Acute Myocardial infarct in people with diabetes is a Dexcom funded study that is investigating whether the use of continuous glucose monitors (Dexcom ONE model) in people with type 2 diabetes facilitates…
- Conditions
- Type 2 Diabetes, Acute Myocardial Infarction, Acute Myocardial Infarction With ST Elevation, Diabetes Complications
- Trial name
- GLAM (NCT05431296)
- Testing
- Dexcom ONE Continuous Glucose Monitoring System
- Where
- United Kingdom
- Volunteers
- 160 people
- Sponsor
- Imperial College London
Type 2 Diabetes
Chronotherapy with Low-dose Aspirin for Primary Prevention
Brief summary: Aspirin (ASA) has been shown to provide marked benefits in primary and secondary prevention of cardiovascular events.
- Trial name
- CARING (NCT00725127)
- Testing
- aspirin
- Where
- 19 sites in Spain
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- University of Vigo
Type 2 Diabetes Mellitus Myocardial Infarction
Ertugliflozin's Effect on Heart Function in Diabetic Patients After Myocardial Infarction
This prospective, randomized, open-label, blinded endpoint (PROBE) trial evaluates the efficacy of early ertugliflozin initiation (10 mg daily) compared to standard care alone on cardiac function in 476 adult patients with type 2…
- Trial name
- NCT07621380
- Testing
- Ertugliflozin 10 mg, Standard AMI Care
- Where
- China
- Volunteers
- 476 people
- Sponsor
- Shanghai Zhongshan Hospital
Diabetes Mellitus, Type 2, Diabetes Complications
Arterial Stiffness and Complication Risk in Type 2 Diabetes
Background The prevalence and incidence of type 2 diabetes is increasing globally. A common complication of diabetes is the disease of the blood vessels, vascular diseases, which can cause disorders like myocardial infarction…
- Conditions
- Diabetes Mellitus, Type 2, Diabetes Complications, Diabetic Angiopathies, Diabetic Nephropathies
- Trial name
- NCT02001532
- Where
- Denmark
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Cardiovascular Diseases, Heart Diseases
VLDL and LDL Particle Types as Coronary Heart Disease Risk Factors
To evaluate very low density lipoprotein (VLDL) and low density lipoprotein (LDL) particle types as predictors of initial coronary events.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Myocardial Infarction
- Trial name
- NCT00065793
- Volunteers
- 1,478 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Familial Hypercholesterolemia - Heterozygous
MYOCARDIAL SILENT INFARCTIONS AND FIBROSIS IN FAMILIAL HYPERCHOLESTEROLEMIA (CHOLCOEUR)
Patients with familial hypercholesterolemia (FH) at high cardiovascular risk may suffer from silent micro-infarctions (MI) before clinical coronary heart disease manifestations because of the lifetime exposure to elevated serum…
- Trial name
- CHOLCOEUR (NCT02517944)
- Where
- France
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Institute of Cardiometabolism and Nutrition, France
Myocardial Infarction, Unstable Angina Pectoris
Beta-cell Function in Glucose Abnormalities and Acute Myocardial Infarction
A three months, double-blind, randomised, parallel-group study evaluating the efficacy of sitagliptin (Januvia™) versus placebo on beta-cell function in patients with newly detected glucose abnormalities and acute myocardial…
- Conditions
- Myocardial Infarction, Unstable Angina Pectoris, Diabetes Mellitus, Impaired Glucose Tolerance
- Trial name
- BEGAMI (NCT00627744)
- Testing
- Sitagliptin
- Where
- 2 sites in Sweden
- Volunteers
- 85 people
- Sponsor
- Karolinska Institutet