Clinical trials: Type2 Diabetes
Diabetes
Post Trial Analysis of a Primary Prevention Study in Asian Indians
An extended follow-up study of NCT00819455 conducted 5 years post randomization. In this study we estimate the incidence of type 2 diabetes among participants enrolled in the diabetes prevention programme.
- Trial name
- NCT02848547
- Testing
- Text Messaging via Short Message Service
- Volunteers
- 537 people, healthy volunteers welcome
- Sponsor
- India Diabetes Research Foundation & Dr. A. Ramachandran's Diabetes Hospitals
Diabetes Mellitus, Type 2
A Study of Postprandial Hyperglycemia in Participants With Type 2 Diabetes
This Study is looking at whether high blood glucose levels after a meal affect arterial stiffness more or less than low blood glucose levels, and whether certain cardiovascular markers influence the outcome of this.
- Trial name
- NCT01159938
- Testing
- Lispro
- Where
- Finland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Obesity, Type 2 Diabetes
Characterization of Metabolic Biomarkers in Varying Subjects
Traditional dietary, lifestyle, behavioral and pharmacologic treatment strategies have proven relatively ineffective for treating obesity, and once metabolic abnormalities such as Type 2 Diabetes (T2D) develop, definitive…
- Trial name
- NCT01199692
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- CPL Associates
Cardiometabolic Disease
Metagenomics and Integrative Systems Medicine of Cardiometabolic Diseases
Supported by state-of-the-art systems medicine competences including integrative computational and functional genomics, the overarching goal of the trial is to investigate the impact of qualitative and quantitative changes in the…
- Trial name
- METACARDIS (NCT02059538)
- Testing
- Adipose tissue biopsies (omental and subcutaneous) liver, CT-scan, Stools sampling
- Where
- 3 sites in Denmark, France and 1 more
- Volunteers
- 2,350 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Health, Obesity Type 2 Diabetes Mellitus
Safety and Tolerability Evaluationof Phascolarcobacterium Faecium
The goal of this interventional study is to assess the safety and tolerability of the daily administratrion of bacterium Phascolarctobacterium faecium in healthy adults with normal weight, and in individuals with overweight and…
- Conditions
- Health, Obesity Type 2 Diabetes Mellitus, Obesity & Overweight
- Trial name
- NCT07285317
- Testing
- Bacterium P. faecium
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Spanish National Research Council
Type 2 Diabetes Mellitus
Dose-response Effect of Pine Nut Oil as a Dual FFA1 and FFA4 Agonist on Glucose Tolerance in Healthy Humans.
Several free fatty acids receptors (FFARs) have been discovered. These have been implicated in metabolic processes and inflammation.
- Trial name
- NCT03305367
- Testing
- Hydrolyzed pine nut oil
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Diabetes Mellitus, Type 2
Subjects With T2D or at Risk of T2D Cohort Follow-up
The main objective of this study is to prospectively follow the subjects included in "Descendance" cohort and to describe the occurrence of type 2 diabetes in non-diabetic subjects, which will allow us to iteratively update the…
- Trial name
- DESCENDANCE (NCT05567692)
- Testing
- OGTT, HbA1c, Questionnaire
- Where
- France
- Volunteers
- 837 people, healthy volunteers welcome
- Sponsor
- Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète
PreDiabetes
Preventing Diabetes With Digital Health and Coaching
The goal of this randomized controlled trial is to determine the efficacy of a digital diabetes prevention program for improving weight, glucose control, and secondary risk factors among people with prediabetes compared to an…
- Trial name
- PREDICTS (NCT03312764)
- Testing
- Online diabetes prevention program, Standard Care
- Where
- United States
- Volunteers
- 598 people, healthy volunteers welcome
- Sponsor
- Omada Health, Inc.
Healthy Participants, Diabetes Mellitus (Type 2)
Effect of Type 2 Diabetes on Biomarker Levels in Albumin Platelet-Rich Fibrin
Diabetes mellitus is a metabolic disease that can negatively affect wound healing and tissue repair. Albumin platelet-rich fibrin (Alb-PRF) is a blood-derived biomaterial used in periodontal and regenerative treatments.
- Trial name
- NCT07672652
- Testing
- Venous blood sampling and Alb-PRF preparation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Type 2 Diabetes Mellitus With Complication
To Compare People With T2DM Who Have Double Hump Versus Who do Not Have Double Hump
Hypothesis: Double Hump in people with T2D is associated with higher magnitude of complication than people with single hump or no hump Objectives: To correlate single and double hump with diabetes complication T2DM patient will…
- Trial name
- NCT06386952
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Diabetes Foundation, India
Type 2 Diabetes Mellitus (T2DM)
A Phase I Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Subcutaneous UBT38006 Injection in Healthy Adult Males
This study is a single-center, randomized, double-blind, placebo- and active-controlled, parallel-group, single-ascending dose (SAD) design.
- Trial name
- NCT07630233
- Testing
- UBT38006, Insulin Degludec Injection, Insulin Icodec Injection
- Where
- China
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- The United Bio-Technology (Hengqin) Co., Ltd.
Diabetes Mellitus, Type 2
A Single Dose Study of LY2189265 in Subjects With Varying Degrees of Hepatic (Liver) Impairment
The primary purpose of this study is to help answer the following research questions, and not to provide treatment for any condition: To evaluate how much of the study drug (LY2189265) is in the blood of participants with varying…
- Trial name
- NCT01253304
- Testing
- LY2189265
- Where
- 2 sites in Germany, Hungary
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Diabetes Mellitus, Type 2
An Online System to Improve Diabetes Self-Care
The purpose of this study is to see if an online program for patients with diabetes helps patients improve their self-care (how they take their medications, what they eat, how much they exercise, and whether they smoke).
- Trial name
- NCT00119938
- Testing
- Access to online patient portal
- Where
- United States
- Volunteers
- 331 people, healthy volunteers welcome
- Sponsor
- Robert Wood Johnson Foundation
Diabetes Mellitus, Type 2
A Study to Determine Acute (After First Dose) and Chronic (After 28 Days) Effects of Empagliflozin (BI 10773) on Pre and Postprandial Glucose Homeostasis in Patients With Impaired Glucose Tolerance and Type 2 Diabetes Mellitus and Healthy Subjects
An open-label, phase II study to assess the acute and chronic effects of empagliflozin (BI 10773)on fasting and postprandial glucose homeostasis in patients with IGT and type 2 diabetes mellitus and assess the acute effects of…
- Trial name
- NCT01248364
- Testing
- BI 10773
- Where
- 3 sites in Austria, Germany and 1 more
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Type 2 Diabetes Mellitus
Safety, Pharmacokinetics and Pharmacodynamics of DSP-8658 in Patients With Type 2 Diabetes Mellitus and Healthy Adults
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of multiple ascending doses of DSP-8658 in patients with Type 2 diabetes mellitus and healthy adults.
- Trial name
- NCT01042106
- Testing
- DSP-8658
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sumitomo Pharma America, Inc.
Diabetes, Diabetes Mellitus, Type 2
A Trial Investigating the Effect of Probenecid and Ciclosporin on the Concentrations of SNAC in Healthy Subjects
The aim of the study is to investigate the effect of the medicines, probenecid and ciclosporin on the concentrations of SNAC. SNAC is an ingredient of the semaglutide tablets.
- Trial name
- NCT03466567
- Testing
- Semaglutide, Probenecid, Ciclosporin
- Where
- Germany
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Obesity, Overweight
A Study of Macupatide (LY3532226) in Participants With Obesity or Overweight Without Type 2 Diabetes
The main purpose of this study is to assess how well macupatide, when dosed alone and in combination with eloralintide, is tolerated and what side effects may occur in participants with obesity or overweight without Type 2…
- Trial name
- NCT07765511
- Testing
- Macupatide, Eloralintide
- Where
- 3 sites in Japan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Type 2 Diabetes
Beta-Cell Function After Near-Normalisation of Blood Glucose
The incretin effect is attenuated in patients with type 2 diabetes mellitus partly due to impaired potentiation of beta-cell responsiveness to glucose by glucose dependent insulinotropic polypeptide and glucagon-like peptide-1…
- Trial name
- NCT00612950
- Testing
- glucagon-like peptide-1,, glucose dependent insulinotropic polypeptide, Saline
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Type 2 Diabetes
Vitamin D Supplementation to Patients With Type 2 Diabetes
The purpose of the study is to evaluate if supplementation with vitamin D in a dose of 40.000 IU per week will result in improved metabolic control in patients with type 2 diabetes.
- Trial name
- NCT00400491
- Testing
- Cholecalciferol (vitamin D)
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Diabetes Mellitus, Type 2, Impaired Glucose Tolerance (IGT)
Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)
HYPOTHESIS: Impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) have distinct pathophysiologic etiologies. Therefore, therapeutic interventions designed to correct the specific underlying pathogenic abnormalities…
- Conditions
- Diabetes Mellitus, Type 2, Impaired Glucose Tolerance (IGT), Impaired Fasting Glucose (IFG)
- Trial name
- NCT02969798
- Testing
- Dapagliflozin, Saxagliptin, Pioglitazone
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
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