Clinical trials: Type2 Diabetes Mellitus
Diabetes, Diabetes Mellitus, Type 2
Treatment Intensification With Biphasic Insulin Aspart 30 in Subjects With Type 2 Diabetes Inadequately Controlled on Sitagliptin and Metformin
This trial is conducted in Asia, Europe, Oceania and South America. The aim of this clinical trial is to generate data demonstrating how to intensify diabetes treatment using BIAsp 30 (biphasic insulin aspart 30) by adding or…
- Trial name
- SIT2MIX (NCT01519674)
- Testing
- biphasic insulin aspart 30, sitagliptin, metformin
- Where
- 69 sites in Argentina, Australia and 8 more
- Volunteers
- 582 people
- Sponsor
- Novo Nordisk A/S
Prediabetes / Type 2 Diabetes, Sedentary Behaviors
Effects of Exercise Snacks on Clinical and Health Outcomes
Physical inactivity and prolonged sedentary behavior are major health concerns, especially for individuals with chronic conditions such as diabetes and prediabetes.
- Conditions
- Prediabetes / Type 2 Diabetes, Sedentary Behaviors, Physical Inactivity
- Trial name
- NCT07609290
- Testing
- Exercise Snacks
- Where
- Taiwan
- Volunteers
- 58 people
- Sponsor
- Chimei Medical Center
Diabetes Mellitus, Type 2
The CANTATA-MP Trial (CANagliflozin Treatment and Trial Analysis - Metformin and Pioglitazone)
The purpose of this study is to evaluate the efficacy and safety of 2 different doses of canagliflozin compared with placebo in patients with type 2 diabetes mellitus who are receving treatment with metformin and pioglitazone and…
- Trial name
- NCT01106690
- Testing
- Canagliflozin, Sitagliptin, Metformin
- Where
- 83 sites in United States, Canada and 9 more
- Volunteers
- 344 people
- Sponsor
- Janssen Research & Development, LLC
Type2 Diabetes, Obesity
mHealth Intervention for Older Adults
This is a pilot study to test the feasibility and acceptability of a self-regulation theory-based mHealth behavior intervention for overweight or obese older adults with T2DM.
- Trial name
- NCT03398590
- Testing
- self-regulation theory-based mHealth behavior intervention
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Boston College
Diabetes Mellitus, Type 2
Examining the Effect of Exogenous Ketone Supplementation on Glucose Control in Type 2 Diabetes
Ketone bodies are a fuel source and signaling molecule that are produced by the body during prolonged fasting or if an individuals consistently eats a low-carbohydrate "keto" diet.
- Trial name
- NCT05155410
- Testing
- Exogenous Ketone Monoester
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of British Columbia
Diabetes Mellitus Type 2
Efficacy and Tolerability of MK0533 in Patients With Type 2 Diabetes (0533-005)
A study to evaluate the effectiveness and tolerability of MK0533 and pioglitazone in patients with type 2 diabetes mellitus.
- Trial name
- NCT00543959
- Testing
- MK0533, Comparator: pioglitazone
- Volunteers
- 346 people
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes Mellitus, Type 2
A Trial Comparing the Efficacy and Safety of GZR4 Injection Versus Insulin Degludec in Subjects with Type 2 Diabetes Mellitus
This study compares the efficacy, safety, and tolerability of once-weekly GZR4 Injection versus once-daily insulin degludec in patients with type 2 diabetes mellitus in inadquete control on oral antidiabetic drug (OAD) therapy or…
- Trial name
- NCT06202079
- Testing
- GZR4 Injection, Insulin Degludec
- Where
- 8 sites in China
- Volunteers
- 179 people
- Sponsor
- Gan and Lee Pharmaceuticals, USA
PreDiabetes, Diabetes type2
Intermittent Fasting to Improve Insulin Secretion
Type 2 diabetes (T2D) mellitus is a challenge for health care systems as the numbers increases constantly. In 2014, 422 million people had been living with diabetes worldwide.
- Conditions
- PreDiabetes, Diabetes type2, Intermittent Fasting, Insulin Secretion
- Trial name
- IFIS (NCT04607096)
- Testing
- Intermittent fasting, Control diet
- Where
- 8 sites in Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital Tuebingen
Type 2 Diabetes Mellitus, Hypertension
Vitamin D and Omega-3 Inhibit Metabolic Syndrome
The study will test the hypothesis that supplementing the diet of subjects with Metabolic Syndrome with 2000 IU vitamin D and 1.8 g omega-3 fatty acids (EPA + DHA) per day, will facilitate weight loss, improve body composition…
- Conditions
- Type 2 Diabetes Mellitus, Hypertension, Hyperlipidemia, Obesity
- Trial name
- NCT01326442
- Testing
- low glycemic diet, vitamin D omega-3
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Guelph
Type 2 Diabetes, Vitamin B12 Deficiency
Effect of Vitamin B12 Supplementation on Glycaemic Control in Uncontrolled Hyperhomocysteinemic Type 2 Diabetic Patients
Increased plasma homocysteine level is associated with macroangiopathy and nephropathy in type 2 diabetes. Also increased levels of serum homocysteine are associated with microalbuminuria which is associated with increased…
- Conditions
- Type 2 Diabetes, Vitamin B12 Deficiency, Hyperhomocysteinemia
- Trial name
- NCT02540642
- Testing
- METHYLCOBALAMIN 500 micrograms
- Where
- India
- Volunteers
- 38 people
- Sponsor
- Smt. Kashibai Navale Medical College and General Hospital
Diabetes Mellitus, Type II
A Clinical Study to Compare the Pharmacokinetic Characteristics of CKD-395 0.5/1000 mg in Healthy Male Volunteers
This study is a randomized, open-label, single dose, 2-way crossover study to compare the pharmacokinetic characteristics of CKD-395 0.5/1000 mg in healthy male volunteers.
- Trial name
- NCT02565368
- Testing
- Duvie Tab. 0.5mg, Glucophage XR Tab. 1000mg, CKD-395 0.5/1000mg
- Where
- South Korea
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Type2 Diabetes, Bisphenol A
Association of Bisphenol A,Paraben Exposure and Type 2 Diabetes
The aim of this study is to evaluate the association between BPA , paraben levels and type 2 DM patients
- Trial name
- NCT05177250
- Testing
- HPLC
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Diabetes Mellitus, Type 2
A Study to Determine the Safety and Efficacy of Albiglutide Administered in Combination With Insulin Glargine
This study will examine the safety and efficacy of albiglutide in combination with insulin glargine as compared with the combination of insulin glargine and preprandial lispro insulin in subjects with type 2 diabetes.
- Trial name
- NCT00976391
- Testing
- albiglutide + insulin glargine, insulin glargine + preprandial lispro insulin
- Where
- 209 sites in United States, Brazil and 12 more
- Volunteers
- 586 people
- Sponsor
- GlaxoSmithKline
Prediabetes, Diabetes Type 1
An Exploratory Clinical Trial to Generate Whole Blood Samples for Analysing Genetic Polymorphisms
G (guanine nucleotide binding) proteins associating with G protein-coupled receptors (GPCR) are key players in the pathogenesis of obesity and diabetes and are targets of pharmacotherapeutic inter-ventions.
- Conditions
- Prediabetes, Diabetes Type 1, Diabetes Type 2
- Trial name
- NCT02057497
- Volunteers
- healthy volunteers welcome
- Sponsor
- Profil Institut für Stoffwechselforschung GmbH
Type2 Diabetes, Heart Failure
Meta-analysis of Fish Oil Supplementation and Cardiovascular Outcomes in Diabetes
Fish oil contains a large amount of long-chain omega-3 polyunsaturated fatty acids, which are considered an important component of a healthy diet.
- Conditions
- Type2 Diabetes, Heart Failure, Myocardial Infarction, Stroke
- Trial name
- NCT04327713
- Testing
- fish oil supplement
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Toronto
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Type 2 Diabetes
Nutritional Therapy and Education With Multimedia Application in Patients With Type 2 Diabetes
The purpose of this study is to evaluate the effectiveness of nutrition therapy in combination with education in diabetes using a multimedia application for improving indicators of metabolic control in patients with type 2…
- Trial name
- NCT02441023
- Testing
- Nutritional therapy and education, Nutritional therapy
- Where
- Mexico
- Volunteers
- 306 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Type2 Diabetes
Breath for Better Health Study
Breath analysis is becoming of increasing interest to researchers throughout the world for disease identification and monitoring.
- Trial name
- NCT03210896
- Testing
- Orange juice
- Where
- United Kingdom
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Obesity Type 2 Diabetes Mellitus
Fecal Microbiota Transplantation (FMT) Combined With Calorie-Restricted Diet and Semaglutide in Patients With Obesity and Type 2 Diabetes
Investigation of the efficacy of fecal microbiota transplantation added to calorie-restricted diet and semaglutide versus calorie-restricted diet and semaglutide alone for weight loss and metabolic improvement in patients with…
- Trial name
- NCT07599046
- Testing
- Fecal microbiota transplantation (FMT), Semaglutide (1 Mg Dose), Calorie-restricted diet
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Eighth Affiliated Hospital, Sun Yat-sen University
Type2 Diabetes, Cognitive Impairment
The Effect of SGLT2 Inhibitors on Cognitive Functions and BDNF Levels in Patients With Type 2 Diabetes
Cognitive impairment is a common complication in diabetes for various reasons. Although glycemic control improves cognitive impairment, different antidiabetic medications' effects on cognitive functions are still being…
- Trial name
- NCT05341388
- Testing
- MOCA cognitive evaluation test, BDNF levels, SF-36 test
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Goztepe Training and Research Hospital