Clinical trials: Type2diabetes
Type2diabetes
Real-World Evaluation of Omarigliptin for Type 2 Diabetes Meliitus in Bangladesh
The study titled "Efficacy and Safety of Omarigliptin, A Weekly Dipeptidyl Peptidase-4 Inhibitor for Type 2 Diabetes Management: Real-World Evaluation in Bangladesh" aims to assess the real-world effectiveness and safety of…
- Trial name
- NCT06449235
- Testing
- Omarigliptin, Sulphonylureas, Metformin
- Where
- Bangladesh
- Volunteers
- 938 people
- Sponsor
- Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders
Type2diabetes
Bioequivalence Study to Compare Empagliflozin/ Metformin HCl 12.5mg/1000mg Film-coated Tablets
Randomized, two-way, two-period, single oral dose, open-label, crossover, bioequivalence study to compare Empagliflozin/ Metformin HCl 12.5mg/1000mg film-coated tablets (12.5mg Empagliflozin / 1000mg Metformin HCl) versus…
- Trial name
- NCT06450262
- Testing
- Emapgliflozin/Metformin 12.5mg/1000mg Film-coated tablets, Synjardy® 12.5mg/1000mg film-coated tablets
- Where
- Jordan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Humanis Saglık Anonim Sirketi
Cardiovascular Diseases, Type2diabetes
Physical Activity and CVD in Adolescents With Type 2 Diabetes
The main research questions for this study are: (1) Is delivering a resiliency-informed behavioural intervention designed to increase physical activity (PA) feasible for adolescents living with Type 2 Diabetes (T2D)? and (2) What…
- Trial name
- CVD (NCT05724888)
- Testing
- Peer mentorship and physical activity
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Obesity, Type2diabetes
Susceptibility to Infectious Diseases in obEsity: an endocRine trAnslational socioLogic Evaluation, "SIDERALE"
Obesity is a life-threatening disease, defined by excessive fat accumulation that increases the risk of other diseases such as cardiovascular events, hypertension, diabetes and cancer.
- Conditions
- Obesity, Type2diabetes, Lipodystrophy, Infections
- Trial name
- SIDERALE2020 (NCT06236932)
- Testing
- Mediterranean diet, Melatonin supplementation
- Where
- 4 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Federico II University
Type2diabetes, Heart Failure
N-terminal Pro-B-type Natriuretic Peptide (NT-proBNP) in Type 2 Diabetes Mellitus
More than 400 million people have type 2 diabetes (T2D) globally, and the burden of diabetes-related cardiovascular complications is increasing.
- Conditions
- Type2diabetes, Heart Failure, Cardiovascular Complication
- Trial name
- PISCES (NCT05745090)
- Where
- Singapore
- Volunteers
- 1,200 people
- Sponsor
- Singapore General Hospital
Type2diabetes
Early Identification of Heart Failure in a High-Risk Diabetic Cohort
Type 2 diabetes is an important co-morbid condition strongly associated with the risk of developing heart failure (HF). Risk scores such as the WATCH-DM score that predict the occurrence of HF among diabetes patients are largely…
- Trial name
- NCT05866380
- Testing
- heart failure risk factors
- Where
- Taiwan
- Volunteers
- 3,500 people
- Sponsor
- Mackay Memorial Hospital
Type2diabetes
Postural Control, Ankle and Trunk Proprioception in Type 2 Diabetes
The investigators aim to assess the postural control, ankle, and trunk proprioception, plantar sensation, and general cognitive status in patients with Type 2 diabetes.
- Trial name
- NCT06045598
- Testing
- Semmes Weinstein Monofilament Test, Proprioception measurement, Postural control assessment
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Hasan Kalyoncu University
Type2diabetes
DM Treatment to Evaluate the Efficacy and Safety of Dapagliflozin or Pioglitazone in Patients with Type 2 Diabetes
Key finding of DM Treatment with combination, A MuLticenter, Randomized, Parallel, Gathering Information of phase 4 Trial to Evaluate the Efficacy and Safety of Dapagliflozin or Pioglitazone add-on to Metformin and DPP-4…
- Trial name
- KLIMT (NCT06875193)
- Testing
- DW6012(Dasidiem tab. 10/100mg)
- Where
- South Korea
- Volunteers
- 196 people
- Sponsor
- Dong Wha Pharmaceutical Co. Ltd.
Type2diabetes, Pregnancy Related
Real Time Continuous Glucose Monitoring System in T2DM With Pregnacy
The prevalence of type 2 diabetes mellitus (T2DM) in women of childbearing age is increasing rapidly, and low glucose compliance leads to an increased risk of adverse pregnancy outcomes for mothers and infants during pregnancy in…
- Conditions
- Type2diabetes, Pregnancy Related, Continuous Glucose Monitoring, Time in Range
- Trial name
- NCT05947916
- Testing
- Real-time Continuous Glucose Monitoring System
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Peking University Third Hospital
Type2diabetes, Insulin Resistance
Effect of Metformin, Dapagliflozin, Combination of Metformin and Pioglitazone in Patients With Type 2 Diabetes
Although, a number of drugs are promising treatment strategies for insulin resistance, a critical question arises to which drug benefits patients with type 2 diabetes more from reduced insulin resistance and consequent glycemic…
- Trial name
- NCT05591235
- Testing
- Metformin, Dapagliflozin, Fixed-dose combination of metformin and pioglitazone (500mg metformin plus 15mg pioglitazone)
- Volunteers
- 60 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Obesity, Childhood, Type2Diabetes
Telehealth Lifestyle Program for Black Adolescent Girls at Risk for Type 2 Diabetes
The aim of this study is to look at changes in diabetes-related risk factors in Black adolescent girls who are at risk for type 2 diabetes and their primary female caregiver after both participating in a 12-week telehealth…
- Trial name
- NCT05396443
- Testing
- Black Girls for Wellness Telehealth
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- Cornell University
Type2diabetes, Frail Elderly Syndrome
The Impact of Geriatric Assessment on the Treatment Plan of Elderly Patients With T2DM
Introduction: With the aging of the world population and the increasing incidence of type 2 diabetes mellitus (T2DM) with age, the number of elderly individuals living with diabetes has been considerably rising.
- Conditions
- Type2diabetes, Frail Elderly Syndrome, Frailty, Geriatric Assessment
- Trial name
- NCT06469437
- Testing
- Providing the physicians with a proposed glycated hemoglobin target
- Where
- Brazil
- Volunteers
- 220 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Type2diabetes, Coronary Artery Disease
Efficacy and Safety of Dapagliflozin for the Hospital Management of Patients With Type 2 Diabetes
The purpose of the trial is to examine whether treatment with dapagliflozin plus insulin as compared with insulin alone (basal-bolus insulin) will result in similar blood glucose control and similar rate of complications in…
- Trial name
- NCT05457933
- Testing
- Dapagliflozin, Glargine
- Where
- India
- Volunteers
- 250 people
- Sponsor
- Medanta, The Medicity, India
Type2diabetes
Promoting Alternatives to Sulfonylureas to Improve Patient Safety in Type 2 Diabetes
Sulfonylurea medications are unsafe for older patients with diabetes. They are associated not only with hypoglycemia, but also with falls and increased cardiovascular risk. Yet they continue to be prescribed frequently.
- Trial name
- NCT05933174
- Testing
- Prompt-sheet, Usual education
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University Hospitals Cleveland Medical Center
Diabetes, Type2Diabetes
A Clinical Guideline-based Management of Type-2 Diabetes by Ayurvedic Practitioners in Nepal
T2DM is a complex disorder which has major health, social and economic consequences. Its chronic hyperglycaemia is associated with macro- and micro-vascular complications and even death. The prevalence of T2DM in Nepal is high.
- Conditions
- Diabetes, Type2Diabetes, Diabetes Mellitus
- Trial name
- NCT05259735
- Testing
- Clinical Guideline based Management, Comparator
- Where
- Nepal
- Volunteers
- 121 people
- Sponsor
- Nepal Health Research Council
Type2diabetes, Obesity
Depletion of Liver Fat in Type 2 Diabetes
The aim of this randomized trial is to determine whether liver fat depletion via a short-term (i.e., two weeks) very-low calorie diet will restore the normal exercise-induced secretion of a signaling protein (fibroblast growth…
- Trial name
- DepLiv (NCT06211556)
- Testing
- Very-low calorie diet
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Type2diabetes
Use of AI in Cardiometabolic Risk Prediction in Asian Indians
The Investigators are recruiting T2DM patients (n, 500) from Fortis-CDOC Hospital. Patients' weight, BMI, lipid profile, liver and kidney function tests, EGG, glycemic parameters, blood pressure, etc.
- Trial name
- NCT05939869
- Testing
- Medical and Clinical History
- Where
- India
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Diabetes Foundation, India
Chronic Kidney Diseases, Type2Diabetes
Decision Support for Detection of Chronic Kidney Disease in Type II Diabetes Mellitus
While data from the National Health and Nutrition Examination Survey (NHANES) estimate that 36.9% of patients with diabetes have CKD, only approximately 10% of patients are aware of their kidney disease.
- Trial name
- CKD-DETECT (NCT05342545)
- Testing
- Alert-based computerized decision support
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Brigham and Women's Hospital
Type2diabetes
Type 2 Diabetes and Blood Brain Barrier Improvement
The majority of T2DM adults show thiamine (vitamin B1) deficiency which may contribute to impaired function. This study will examine patients with T2DM through brain MRI scans, cognition assessments, blood tests, and…
- Trial name
- NCT06322212
- Testing
- Thiamine
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of California, Los Angeles
Overweight and Obesity, Type2diabetes
Assessment of Safety, Tolerability and Drug Levels of Exenatide Implant
The purpose of this study is to evaluate the safety, tolerability and drug levels of an exenatide implant administered subcutaneously.
- Trial name
- LIBERATE-1 (NCT05670379)
- Testing
- Exenatide Implant, Bydureon BCise (exenatide extended release), Semaglutide, 1.0 mg/mL
- Where
- Australia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vivani Medical, Inc