Clinical trials: URTI
Cryotherapy Effect
The Effect of Brief Skin Cooling on Isometric Muscle Strength
There is sympathetic innervation of the muscular spindle. The application of cold to the skin provides an increase in sympathetic activity.
- Trial name
- NCT06079437
- Testing
- Cheer, The cold pressure test
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Procedural Pain Relief, Fear Pain
Pharmacological and Nonpharmacological Methods for Children in Venipuncture Pain
This study aimed to examine the effect of EMLA cream, cold spray, and Buzzy applied during venipuncture on the pain and fear levels of children aged 7-12 years.
- Trial name
- NCT06901271
- Testing
- EMLA Cream, Buzzy, Cold spray
- Where
- Turkey (Türkiye)
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Aynur Aytekin Ozdemir
Psychological and Behavioral Symptoms
Self-efficacy Training to Facilitate Taking Cold Showers
The primary goal of this study is to determine whether a self-efficacy training can increase the probability of taking cold showers regularly over a three-month period.
- Trial name
- TCS (NCT07120022)
- Testing
- Self-efficacy training
- Where
- Switzerland
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Needle Phobia, Needle Fear
Determining Whether There is a Change in Time Taken to Return to Homeostatic Temperature With Repeated Exposure to a Cold Stressor
There has been previous research suggesting cold has an effect on pain relief, however there is limited knowledge on the relationship between exposure time of a cold stressor and how long it takes to return to homeostatic…
- Conditions
- Needle Phobia, Needle Fear, Injection Fear
- Trial name
- NCT05713539
- Testing
- Metal block
- Where
- United Kingdom
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- The Whiteley Clinic
Type 2 Diabetes, Cold Acclimation
Chronic Cold Acclimation Stimulates the Browning of Subcutaneous White Adipose in Patients With Type 2 Diabetes Mellitus
Adipose tissues, which include white adipose tissue (WAT) and brown adipose tissue (BAT), play an essential role in regulating whole-body energy homeostasis.
- Trial name
- NCT02775253
- Testing
- Chronic cold acclimation
- Where
- China
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Xiang Guang-da
Allergic Rhinitis, Non-Allergic Rhinitis
Detection and Use of Nasal Nitrous Oxide and the Electronic Nose
Introduction: Rhinitis, sinonasal polyposis (SP) and asthma are diseases whose pathogenesis is based on inflammation. This will determine the presence of disease, its evolution and its treatment.
- Conditions
- Allergic Rhinitis, Non-Allergic Rhinitis, Nasal Polyps
- Trial name
- EPONA (NCT02476929)
- Testing
- Nasal nitrous oxide, Electronic nose
- Where
- Spain
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Acute Respiratory Infection, Asthma Exacerbations
Reusable Face Masks to Reduce Risk of Viral Respiratory Infections and Asthma Exacerbations
REMASK trial is a Trial within Cohort study (TwiCs), nested within the COVIDENCE UK longitudinal study. It has been designed to determine whether the offer of a free reusable, elastomeric face mask to adults with asthma and other…
- Trial name
- REMASK (NCT06885229)
- Testing
- FloMask - reuseable face mask
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Health Behavior
Cold Water Immersion in the Recovery of Markers of Muscle Damage of 10km Street Runners
Objective: To analyze the effect of cold water immersion (CWI) on the recovery of clinical, biochemical, functional and neuromuscular markers of muscle damage in 10 km street runners.
- Trial name
- NCT03094689
- Testing
- Cold water immersion, Water immersion
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
to Improve the Effectiveness of a Amino Acid Dietary Supplement in Chronic Pharyngeal Infections vs Placebo
Amino Acid Composition Reduces Frequency of Common Cold. Results of a Controlled Completely Masked Trial
The purpose of this study is to investigate the effectiveness of a dietary supplement with high dosage of amino acids and vitamins in the treatment of acute and chronic infection of pharyngeal area known as common cold. T
- Trial name
- NCT01414335
- Testing
- amino acid composition
- Where
- Germany
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Kyberg Vital GmbH
Paramyxoviridae Infections, Virus Diseases
Safety of and Immune Response to Recombinant Live Attenuated Parainfluenza Type 3 Virus Vaccine in Healthy Infants and Children
Human parainfluenza viruses (HPIVs) are a major health concern in infants and young children under 5 years of age, causing serious respiratory tract disease.
- Trial name
- NCT01021397
- Testing
- rHPIV3cp45
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Healthy
Immunogenicity and Safety of Live Attenuated Influenza Vaccine (Flumist) Administered by Nasal and Sublingual Route
Background: It is well established that live attenuated organisms can be highly effective vaccines, immune responses elicited can often be of greater magnitude and of longer duration than those produced by non-living antigens and…
- Trial name
- NCT01488188
- Testing
- Influenza vaccine
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- International Vaccine Institute
Lung Cancer, Small Cell Lung Cancer
A Multicenter Clinical Trial of Sputum DNA Testing for Lung Cancer in China
The primary objective of this study is to assess the safety and effectiveness of Human Multigene Methylation Detection Kit (Fluorescent PCR Method) for help diagnose lung cancer by comparing with clinical standard method…
- Conditions
- Lung Cancer, Small Cell Lung Cancer, Non-Small Cell Lung Cancer, Squamous Cell Carcinoma
- Trial name
- NCT05337163
- Testing
- Diagnostic Test: Sputum DNA methylation analysis, chest CT or pathological examination
- Where
- China
- Volunteers
- 1,564 people, healthy volunteers welcome
- Sponsor
- Creative Biosciences (Guangzhou) Co., Ltd.
Cryotherapy Effect
The Effects of Cold Water Immersion With Different Dosages (Duration and Temperature Variations) on Heart Rate Variability Post-exercise Recovery
The aim of the present study was to investigate the effects of cold water immersion (CWI) during post-exercise recovery with different durations and temperatures on heart rate variability (HRV) indices.
- Trial name
- NCT02499640
- Testing
- immersion cold water
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Paulista University
Viral Infections of the Upper Respiratory Tract
Probiotics in Prevention of Common Cold
The objective of this study is to assess the benefit and tolerability of a probiotic product in subjects with increased susceptibility to common cold.
- Trial name
- NCT02013934
- Testing
- Probiotic
- Where
- Germany
- Volunteers
- 899 people, healthy volunteers welcome
- Sponsor
- Probi AB
Common Cold
Kinetics of Etheric Oils, Smart Textiles vs. Ointment
The purpose of the study is to determine whether the application form of etheric oils (camphor, cineol and menthol) causes changes in the concentration of this agents in the exhaled air.
- Trial name
- NCT00299559
- Testing
- smart textiles containing menthol, camphor, cineol
- Where
- Germany
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Influenza
Trial to Determine the Safety and Efficacy of Influenza Virus Vaccine, Trivalent, Types A & B, Live Cold- Adapted (CAIV-T) in Healthy Children Attending Day Care Centers
The purpose of this study is to determine the efficacy of the liquid formulation of CAIVT against culture confirmed influenza illness in healthy children aged at least 6 months and less than 36 months, attending day care centers…
- Trial name
- NCT00192283
- Testing
- CAIV-T
- Where
- Finland
- Volunteers
- 2,903 people, healthy volunteers welcome
- Sponsor
- MedImmune LLC
Brown Adipose Tissue
Short Term Effect of Glucocorticoids on Brown Adipose Tissue Thermogenesis in Humans
Interventional, Placebo controlled cross-over study to investigate the short-term effects of glucocorticoids (prednisone) on human brown adipose tissue.
- Trial name
- GlucoBAT (NCT03269747)
- Testing
- Prednisone
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Cold Exposure
Cold Water Exposure's Effects on Physical and Mental Health
An interest in cold-water immersion (CWI) to elicit diverse physiological effects has been prevalent for centuries. CWI typically consists of bodily exposure to water at temperatures ranging from 5-10º C for various durations.
- Trial name
- NCT06667193
- Testing
- Cold Water Immersion (CWI) - Cold Tub Immersion (CI), Cold Water Immersion (CWI) - Cold Shower (CS)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Northern Colorado
Cutaneous Manifestations, Skin Manifestations
Cutaneous Manifestations of Coronavirus Disease 2019(COVID-19).
An outbreak of Corona virus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-coV-2) occurred in Wuhan city, Hubei province, China in December 2019.
- Conditions
- Cutaneous Manifestations, Skin Manifestations, COVID-19, COVID-19 Pneumonia
- Trial name
- NCT05094687
- Where
- Pakistan
- Volunteers
- 1,206 people, healthy volunteers welcome
- Sponsor
- Jinnah Postgraduate Medical Centre
Cold Exposure
Effects of Winter Swimming on Blood Indicators and Oxidative Stress in Males
Exposure of the human body to cold water triggers numerous beneficial physiological changes. The study aimed to assess the impact of regular winter swimming on blood morphological, rheological, and biochemical indicators and…
- Trial name
- NCT06223087
- Testing
- winter swimming
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University School of Physical Education, Krakow, Poland