Clinical trials: URTI - Viral Upper Respiratory Tract Infection
Coronavirus Disease 2019, Coronavirus Disease 2019 (COVID-19)
A Study of How Ibuzatrelvir is Taken up Into the Blood of Healthy Adults After Taking Different Tablets of Ibuzatrelvir
Healthy adults will be enrolled into this open-label, Phase 1 research study. Participants will spend about 9 nights and 10 days in the clinical research unit (CRU) and the total time in the study will be about 11 weeks.
- Conditions
- Coronavirus Disease 2019, Coronavirus Disease 2019 (COVID-19), COVID-19 (Coronavirus Disease 2019), Upper Respiratory Tract Infections
- Trial name
- NCT07552779
- Testing
- Ibuzatrelvir co-process API film coated tablet, Ibuzatrelvir filmcoated tablet
- Where
- Belgium
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Pfizer
Respiratory Tract Viral Infections, Human Metapneumovirus (hMPV) Infection
Study of ALVR106 in Patients With Respiratory Viral Infections After Hematopoietic Cell and Solid Organ Transplant
A study to evaluate ALVR106; an allogeneic, off-the-shelf multi-virus specific T cell therapy that targets four community acquired respiratory viruses: respiratory syncytial virus (RSV), influenza, human metapneumovirus (hMPV)…
- Conditions
- Respiratory Tract Viral Infections, Human Metapneumovirus (hMPV) Infection, Parainfluenza (PIV) Infection, Respiratory Syncytial Viral (RSV) Infection
- Trial name
- NCT04933968
- Testing
- ALVR106
- Where
- 21 sites in United States
- Volunteers
- 17 people
- Sponsor
- AlloVir
Viral Upper Respiratory Tract Infection
Randomized Controlled Trial of Vitamin D3 Supplementation for Viral Upper Respiratory Tract Infections (URI) Prevention
Background: Vitamin D has been shown to be an important immune system regulator. Vitamin D insufficiency during the winter may cause increased susceptibility to infections, particularly viral upper respiratory tract infections…
- Trial name
- NCT00656929
- Testing
- Vitamin D3
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Winthrop University Hospital
Infection Viral
Xanthohumol and Viral Infections (XL)
The aim of the present study is to determine if a regular oral supplementation of xanthohumol attenuate the severity of symptoms and duration of´viral infections.
- Trial name
- NCT06286657
- Testing
- Xanthohumol
- Where
- Austria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Vienna
URTI - Viral Upper Respiratory Tract Infection
A Study to Assess the Effect Probiotic Supplement on Immune Health in Teachers Prone to Upper Respiratory Tract Infection
The present study is a randomized, placebo-controlled, double-blind, parallel-group clinical studydesigned to assess the effects of IP on immune health in teachers prone to URTI.
- Trial name
- NCT07033754
- Testing
- Propionibacterium freudenreichii P.UF1, Microcrystalline cellulose, calciumcarbonate, Mg Stearate, Sylysia
- Where
- 6 sites in India
- Volunteers
- 100 people
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
URTI - Viral Upper Respiratory Tract Infection
Evaluation Viral RNA and Virus Infectivity in Exhaled Air Before and After Use of One Dose With ColdZyme Mouth Spray
Many respiratory diseases spread through aerosols. ColdZyme is a mouth spray that protects against upper respiratory tract viruses causing common cold and flu-like symptoms.
- Trial name
- NCT07041671
- Testing
- ColdZyme
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Lund University
Influenza, Acute Upper Respiratory Infection
Treatment of Influenza and ARVI in Children by Kagocel ®
This study examined the etiology of acute respiratory viral infections (ARVI) during the 2015-2016 season, evaluated the statistics of the incidence of influenza and ARVI in this period (epidemiology: severity of the disease and…
- Trial name
- NCT04651491
- Testing
- Kagocel
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Nearmedic Plus LLC
Lower Respiratory Tract Infection, Acute Bronchitis
Evaluating a Host-response Based Diagnostic for Distinguishing Between Bacterial and Viral Etiology in Patients With Lower Respiratory Tract Infection (LRTI)
The purpose of this study is to validate the diagnostic accuracy of a novel host-response based diagnostic tool for differentiating between bacterial and viral etiologies in adult patients aged 18 years and older with clinical…
- Conditions
- Lower Respiratory Tract Infection, Acute Bronchitis, Pneumonia, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- OBSERVER (NCT03011515)
- Where
- Israel
- Volunteers
- 583 people, healthy volunteers welcome
- Sponsor
- MeMed Diagnostics Ltd.
Influenza, Respiratory Viral Infection
A Study to Evaluate the Safety and Efficacy of XC221 in Patients With Uncomplicated Influenza or Other Acute Viral Upper Respiratory Infections
The main purpose of the study was to evaluate the effectiveness of XC221, tablets, at a dose of 200 mg/day compared to placebo in patients with uncomplicated influenza or other acute respiratory viral infections (ARIs).
- Trial name
- NCT05544916
- Testing
- XC221
- Where
- 13 sites in Russia
- Volunteers
- 260 people
- Sponsor
- Valenta Pharm JSC
Virus Diseases in Children
A Study to Investigate the Effect of Probiotics (L. Reuteri ATCC PTA 5289 and L. Reuteri DSM 17938) on Symptoms of Viral Upper Respiratory Tract Infections in Children
This study investigates the effect of Lactobacillus reuteri probiotic strains (ATCC PTA 5289 and DSM 17938) on symptoms of viral upper-respiratory tract infections in children.
- Trial name
- NCT06205966
- Testing
- BioGaia Pharax (L. reuteri PTA 5289 and DSM 17938)
- Where
- Hungary
- Volunteers
- 142 people
- Sponsor
- Milosevits Gergely
Viral Pharyngitis
Effect of Cetylpyridinium Chloride (CPC) Rinse in Viral Upper Respiratory Tract Infections (vURTI)
This is a randomized, controlled clinical trial with two parallel groups in which 150 volunteers (75 per group) will receive either VITIS CPC Protect® mouthwash (Mouthwash with cetylpyridinium chloride (CPC) as an anti-plaque…
- Trial name
- NCT06251089
- Testing
- CPC mouthwash
- Where
- Spain
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Dentaid SL
Falls Injury, Falls
Potential of Interface Care Models to Deliver More Appropriate Care to Patients With Acute Medical Illness
Every country in the world is experiencing growth in both the size and the proportion of older persons. As a result of the changes, the profile and needs of people with medical illnesses have evolved.
- Conditions
- Falls Injury, Falls, Hospitalization in Acute Care, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- NCT07536035
- Where
- Singapore
- Volunteers
- 220 people
- Sponsor
- National University Hospital, Singapore
Viral Gastro Enteritis, Pharyngitis
Impact of Handing to Patients a Copy of the Consultation Report on Their Medicine Consumption
In France, patients with benign viral infections (ie: gastro enteritis and/or rhinopharyngitis, etc.) often receive several prescriptions from their doctors, although there is evidence that these medicines are not efficient.
- Trial name
- NCT02237573
- Testing
- Written medical report and standardized medical advices, Control
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Paris 7 - Denis Diderot
Upper Respiratory Infection, Common Cold
The Natural History of Viral Upper Respiratory Infections in Children Aged 6 to Less Than 14 Years
This study examines the cold processes of children aged 6 to less than 14. Children will be seen by the study staff 6 days in a row during the course of their naturally-acquired colds.
- Trial name
- NCT00405509
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- West Penn Allegheny Health System
Upper Respiratory Tract Infections
Impact of Echinacea as Prophilaxis for Upper Respiratory Tract Infections in Children 1-5 Years
Acute upper respiratory tract infections are the most commmon infections in children and are associated with complications such as acute otitis media, sinusitis and pneumonia.
- Trial name
- NCT01396889
- Testing
- Echinacea
- Where
- Iran
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hormozgan University of Medical Sciences
Common Cold
Efficacy and Safety Study of Homeopathic Oral Antibodies to Treat Viral Upper Respiratory Tract Infections
The purpose of this study is to determine whether early self-treatment with homeopathic dilutions of oral antibodies to a key-protein of the immune system are effective and safe in the treatment of viral upper respiratory tract…
- Trial name
- ESTUAR (NCT01651715)
- Testing
- TAO1, oral homeopathic antibodies
- Where
- 33 sites in Belgium
- Volunteers
- 232 people
- Sponsor
- Theranor s.p.r.l
Common Cold, Upper Respiratory Tract Infections
Hypertonic Saline Nasal Irrigation and Gargling for the Common Cold.
Viral upper respiratory tract infections (URTI), one of the commonest infection faced by humans, have a significant impact on individuals, families, health service and economy.
- Trial name
- ELVIS (NCT02438579)
- Testing
- Nasal Irrigation & Gargling
- Where
- United Kingdom
- Volunteers
- 66 people
- Sponsor
- NHS Lothian
Respiratory Tract Infections, Fever
Placebo and Active Controlled Study to Compare the Antipyretic Efficacy of Aspirin® in Patients With Acute Febrile Upper Respiratory Tract Infections Suspected to be of Viral Origin
This study is addressed to patients suffering from an acute febrile upper respiratory tract infection suspected to be of viral origin.
- Trial name
- NCT01464944
- Testing
- Acetylsalicylic acid (Aspirin, BAYE4465), Paracetamol
- Where
- 9 sites in Russia, Ukraine
- Volunteers
- 392 people
- Sponsor
- Bayer
COVID-19, SARS-CoV-2
Nigella Sativa in COVID-19
Natural products with immunomodulation and antiviral activity showed a promising improvement in the outcomes of some viral infectious diseases both in preclinical and primitive clinical studies.
- Trial name
- NCT04401202
- Testing
- Nigella sativa oil
- Where
- Saudi Arabia
- Volunteers
- 183 people
- Sponsor
- King Abdulaziz University
Acute Cough
Study of Gefapixant (MK-7264) in Acute Cough for Participants With Induced Viral Upper Respiratory Tract Infection (URTI) (MK-7264-013)
The purpose of the study is to evaluate the efficacy, safety, and tolerability of gefapixant (MK-7264) in adult participants with induced viral upper respiratory tract infections (URTI).
- Trial name
- NCT03569033
- Testing
- Gefapixant
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC