Clinical trials: URTI - Viral Upper Respiratory Tract Infection
Influenza, Acute Upper Respiratory Infection
Treatment of Influenza in Routine Clinical Practice
This study evaluates the statistics of influenza and acute respiratory viral infections (ARVI) management in outpatient sites in Russia, Armenia, Moldova and Georgia (epidemiology: disease severity and bacterial exacerbations…
- Trial name
- FLU-EE (NCT02983019)
- Testing
- Kagocel
- Where
- 4 sites in Armenia, Georgia and 2 more
- Volunteers
- 18,946 people
- Sponsor
- Nearmedic Plus LLC
Viral Upper Respiratory Tract Infection
Randomized Controlled Trial of Vitamin D3 Supplementation for Viral Upper Respiratory Tract Infections (URI) Prevention
Background: Vitamin D has been shown to be an important immune system regulator. Vitamin D insufficiency during the winter may cause increased susceptibility to infections, particularly viral upper respiratory tract infections…
- Trial name
- NCT00656929
- Testing
- Vitamin D3
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Winthrop University Hospital
Asthma
Clinical Trial of Fluticasone Versus Placebo at the Onset of a Cold for Children With Asthma
The purpose of this study is to determine, in children aged 1 to 6 years with recurrent asthma induced by upper respiratory tract infections (URTI), whether the administration of high doses of inhaled fluticasone started at the…
- Trial name
- NCT00238927
- Testing
- inhaled fluticasone 750 mcg/day twice daily until 2 days without symptoms (maximum 15 consecutive days)
- Where
- 5 sites in Canada
- Volunteers
- 150 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Influenza, Respiratory Viral Infection
A Study to Evaluate the Safety and Efficacy of XC221 in Patients With Uncomplicated Influenza or Other Acute Viral Upper Respiratory Infections
The main purpose of the study was to evaluate the effectiveness of XC221, tablets, at a dose of 200 mg/day compared to placebo in patients with uncomplicated influenza or other acute respiratory viral infections (ARIs).
- Trial name
- NCT05544916
- Testing
- XC221
- Where
- 13 sites in Russia
- Volunteers
- 260 people
- Sponsor
- Valenta Pharm JSC
Respiratory Tract Infections, Fever
Placebo and Active Controlled Study to Compare the Antipyretic Efficacy of Aspirin® in Patients With Acute Febrile Upper Respiratory Tract Infections Suspected to be of Viral Origin
This study is addressed to patients suffering from an acute febrile upper respiratory tract infection suspected to be of viral origin.
- Trial name
- NCT01464944
- Testing
- Acetylsalicylic acid (Aspirin, BAYE4465), Paracetamol
- Where
- 9 sites in Russia, Ukraine
- Volunteers
- 392 people
- Sponsor
- Bayer
Falls Injury, Falls
Potential of Interface Care Models to Deliver More Appropriate Care to Patients With Acute Medical Illness
Every country in the world is experiencing growth in both the size and the proportion of older persons. As a result of the changes, the profile and needs of people with medical illnesses have evolved.
- Conditions
- Falls Injury, Falls, Hospitalization in Acute Care, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- NCT07536035
- Where
- Singapore
- Volunteers
- 220 people
- Sponsor
- National University Hospital, Singapore
Common Cold
Efficacy and Safety Study of Homeopathic Oral Antibodies to Treat Viral Upper Respiratory Tract Infections
The purpose of this study is to determine whether early self-treatment with homeopathic dilutions of oral antibodies to a key-protein of the immune system are effective and safe in the treatment of viral upper respiratory tract…
- Trial name
- ESTUAR (NCT01651715)
- Testing
- TAO1, oral homeopathic antibodies
- Where
- 33 sites in Belgium
- Volunteers
- 232 people
- Sponsor
- Theranor s.p.r.l
Influenza, Pneumonia
Oseltamivir Randomised Controlled Efficacy Trial
Background In preparation for a global influenza pandemic, there is an urgent need for representative data from populations and settings where the pandemic is most likely to arise.
- Conditions
- Influenza, Pneumonia, Lower Respiratory Tract Infection, Upper Respiratory Tract Infection
- Trial name
- NCT00707941
- Testing
- Oseltamivir
- Where
- Bangladesh
- Volunteers
- 1,190 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
COVID-19, SARS-CoV-2
Nigella Sativa in COVID-19
Natural products with immunomodulation and antiviral activity showed a promising improvement in the outcomes of some viral infectious diseases both in preclinical and primitive clinical studies.
- Trial name
- NCT04401202
- Testing
- Nigella sativa oil
- Where
- Saudi Arabia
- Volunteers
- 183 people
- Sponsor
- King Abdulaziz University
Covid19, Atherosclerosis
A Pragmatic Randomized Trial of Icosapent Ethyl for High-Cardiovascular Risk Adults
MITIGATE is a prospective, open-label, parallel-group, randomized, pragmatic clinical trial. The MITIGATE Study has been designed to evaluate the real-world clinical effectiveness of pre-treatment with icosapent ethyl (IPE), also…
- Conditions
- Covid19, Atherosclerosis, Cardiovascular Diseases, Upper Respiratory Tract Infections
- Trial name
- MITIGATE (NCT04505098)
- Testing
- Icosapent ethyl
- Where
- United States
- Volunteers
- 39,600 people
- Sponsor
- Kaiser Permanente
Viral Upper Respiratory Tract Infection, Gastroenteritis
Probiotic Supplementation and Endurance Performance in Cyclists and Masters Runners
The study will evaluate the change in gastrointestinal (GI) flora following probiotic supplementation, and expected to lead to an increase in the intestinal epithelial integrity and to improvement in its health.
- Trial name
- NCT02756221
- Testing
- Probiotics
- Where
- Israel
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Tel Hai College
COVID-19, Vaccine-Preventable Diseases
The Efficacy of the 2023-2024 Updated COVID-19 Vaccines Against COVID-19 Infection
The purpose of this research study is to find out how well two different 2023-2024 updated COVID-19 vaccines protect people from COVID-19 (the disease caused by the SARS-CoV-2 virus), and to determine if getting a 2023-2024…
- Conditions
- COVID-19, Vaccine-Preventable Diseases, SARS CoV 2 Infection, Upper Respiratory Tract Infection
- Trial name
- BEEHIVE (NCT06065176)
- Testing
- Novavax COVID-19 vaccine (2023-2024 formula XBB containing), Pfizer COVID-19 mRNA vaccine (2023-2024 formula XBB containing)
- Where
- United States
- Volunteers
- 1,188 people, healthy volunteers welcome
- Sponsor
- Sarang K. Yoon, DO, MOH
Influenza, Viral Respiratory Infection
A Study to Evaluate the Safety, Tolerability and Efficacy of XC221 in Patients With Uncomplicated Influenza or Other Acute Viral Upper Respiratory Infections
A multicenter, randomized, double-blind, placebo controlled comparative study to evaluate the safety, tolerability and efficacy of XC221 used at 100 mg daily and at 200 mg daily in patients with uncomplicated influenza or other…
- Conditions
- Influenza, Viral Respiratory Infection, Acute Viral Upper Respiratory Infections
- Trial name
- NCT05030324
- Testing
- XC221 100 mg, XC221 200 mg
- Where
- 9 sites in Russia
- Volunteers
- 255 people
- Sponsor
- Valenta Pharm JSC
Viral Upper Respiratory Tract Infection
ARMS-I (a Formulation of Cetylpyridinium Chloride -CPC)
This is a single center study to evaluate the pharmacokinetics of ARMS-I a formulation that incorporates cetylpyridinium chloride (CPC), administered once as a single dose of three sprays orally, followed by multiple dosing (3x…
- Trial name
- ARMS-I (NCT03026205)
- Testing
- ARMS-I
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Toledo Health Science Campus
Acute Respiratory Infection, Asthma Exacerbations
Reusable Face Masks to Reduce Risk of Viral Respiratory Infections and Asthma Exacerbations
REMASK trial is a Trial within Cohort study (TwiCs), nested within the COVIDENCE UK longitudinal study. It has been designed to determine whether the offer of a free reusable, elastomeric face mask to adults with asthma and other…
- Trial name
- REMASK (NCT06885229)
- Testing
- FloMask - reuseable face mask
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Acute Upper Respiratory Tract Infection, Influenza
Kagocel® for the Prevention of ARVI and Influenza in Young People
This study evaluates the use of Kagocel for the prevention of acute respiratory viral infections (ARVI) and influenza during the epidemic rise in the incidence of diseases in Russia in 2018 (epidemiology: the number of cases…
- Conditions
- Acute Upper Respiratory Tract Infection, Influenza, Respiratory Viral Infection
- Trial name
- NCT04626622
- Testing
- Kagocel, No one
- Where
- Russia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Nearmedic Plus LLC
COVID-19, Upper Respiratory Infection
A Noninvasive Multimodal Biosensing Device for Screening and Monitoring Response to Treatment of Infectious Respiratory Diseases
Background: The COVID-19 outbreak has strained the health care system. New tools are needed for diagnostic testing and monitoring of people who have the virus.
- Conditions
- COVID-19, Upper Respiratory Infection, Lower Respiratory Infection
- Trial name
- NCT05035420
- Testing
- Fitbit, Douglas Bag, Periflux 6000 EPOS
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Viral Upper Respiratory Tract Infection
A Study to Examine the Duration of Effect of PrEP-001 in Healthy Subjects Challenged With HRV-16
A study to examine the duration of effect of PrEP-001 in healthy subjects challenged with HRV-16
- Trial name
- NCT03338556
- Testing
- PrEP-001
- Where
- United Kingdom
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Prep Biopharm Limited
Upper Respiratory Infection, Common Cold
The Natural History of Viral Upper Respiratory Infections in Children Aged 6 to Less Than 14 Years
This study examines the cold processes of children aged 6 to less than 14. Children will be seen by the study staff 6 days in a row during the course of their naturally-acquired colds.
- Trial name
- NCT00405509
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- West Penn Allegheny Health System
Upper Resp Tract Infection, Rhinitis Acute
Evaluation of a Hypertonic Seawater Aerosol Therapy Solution in Adults and Children
The purpose of this study is to evaluate the tolerance, the performance and safety of this device, 22‰ Hypertonic seawater aerosol therapy solution in unidose container, to treat adult and peadiatric patients with of upper…
- Conditions
- Upper Resp Tract Infection, Rhinitis Acute, Rhinopharyngitis, Cold Symptom
- Trial name
- AIR (NCT07267689)
- Testing
- Treatment (22‰ Hypertonic seawater aerosol therapy solution)
- Where
- 4 sites in Poland
- Volunteers
- 110 people
- Sponsor
- Laboratoires Gilbert