Clinical trials: Ulcer
Inflammatory Bowel Disease, Ulcerative Colitis
Assessment of Colonic Permeability by Confocal Laser Endomicroscopy
The purpose of this study is to evaluate the efficacy of confocal laser endomicroscopy in assessment of colonic permeability against conventional sugar absorption test.
- Conditions
- Inflammatory Bowel Disease, Ulcerative Colitis, Irritable Bowel Syndrome
- Trial name
- NCT00883077
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shandong University
Pressure Injury, Military Activity
Pressure Injury Prevention in AE and PFC
This study evaluates the effect of a multilayer skin dressing (Mepilex) placed on the sacrum or a fluid filled pad (LiquiCell) on risk factors for pressure injuries under conditions consistent with military long-distance…
- Trial name
- NCT03924622
- Testing
- Mepilex, LiquiCell
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Washington
Ulcerative Colitis
Study for Safety and Tolerability of TOP1288 Administered Orally in Healthy Subjects
This study evaluates the safety and tolerability of TOP1288 oral single ascending and multiple doses in healthy subjects.
- Trial name
- NCT03071081
- Testing
- TOP1288
- Where
- United Kingdom
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Topivert Pharma Ltd
Diabetic Ulcer
Evaluation of Topical Wound Oxygen (two2) Therapy
The purpose of this study is to evaluate the efficacy of the Topical Wound Oxygen (two2) therapy system on the healing of diabetic lower extremity ulcers.
- Trial name
- NCT00871312
- Testing
- Topical wound oxygen therapy
- Where
- 3 sites in United States, Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- AOTI Ltd.
Diabetic Foot, Diabetic Dermopathy
The Role of Skin Microecology in Diabetic Skin Lesions
This study is an observational study. Collect cotton swabs of the surface skin are obtained from the non-diabetic and diabetic patients hospitalized in the Nanfang Hospital of Southern Medical University.
- Trial name
- NCT04916457
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Ulcerative Colitis, Crohn's Colitis
RCT: HDWL vs Virtual Chromoendoscopy in the Detection of Intraepithelial Neoplasia in Longstanding Colitis
Colitis is inflammation of the large bowel and it is often caused by conditions known as ulcerative colitis and Crohn's disease.
- Trial name
- VIRTUOSO (NCT02822352)
- Testing
- Chromoendoscopy
- Where
- United Kingdom
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Ulcerative Colitis
Use of Rectal Dialysis Technique to Measure Rectal 5-ASA Levels in Healthy Volunteers Receiving Asacol
The investigators plan to develop a novel method of estimating 5-ASA levels in the rectum at a mucosal level using in vivo rectal dialysis technique towards the eventual goal of determining the optimal dosing of Asacol® that…
- Trial name
- NCT04032652
- Testing
- Rectal dialysis
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Ulcerative Colitis
Role of Roflumilast in Ulcerative Colitis
This study aims to investigate possible efficacy and safety of Roflumilast in adult patients with ulcerative colitis disease .
- Trial name
- NCT05684484
- Testing
- Roflumilast 500 MCG Oral Tablet [DALIRESP], amino salicylic acid
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tanta University
Juvenile Idiopathic Arthritis (JIA), Crohn Disease (CD)
Study on Eating Habits and Association with "omic" Profiles in Families with a Subject Affected by a Chronic Immune-mediated Inflammatory Pathology. Observational Multicenter Study.
The proposed study is part of a PNRR 2022 project (call "Non-Communicable Chronic Diseases (NCDs) with high impact on healthcare and social assistance systems," currently awaiting funding response) and represents the continuation…
- Conditions
- Juvenile Idiopathic Arthritis (JIA), Crohn Disease (CD), Ulcerative Colitis (UC)
- Trial name
- DIETA-MICIREUM (NCT06862843)
- Testing
- Collecting questionnaires and biological samples
- Where
- 4 sites in Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Meyer Children's Hospital IRCCS
Diabetic Foot
Fitostimoline® Hydrogel Versus Saline Gauze Dressing in Diabetic Foot Ulcers
Diabetes Mellitus (DM) is one of the most widespread metabolic diseases and the alarming rise in its prevalence worldwide poses enormous challenges.
- Trial name
- NCT05661474
- Testing
- Fitostimoline ® hydrogel group, Saline gauze group
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federico II University
IBD (Inflammatory Bowel Disease), IBD
Exploring Fecal Calprotectin Levels, Maternal and Infant Microbiota, Infant Health, Nutrition, and Adverse Pregnancy Outcomes With Patient With Inflammatory Bowel Disease
The goal of this prospective longitudinal cohort study is to examine how the human microbiome of pregnant women-including bacteria and fungi in the gastrointestinal tract, vaginal canal, skin, and breastmilk-may influence infant…
- Conditions
- IBD (Inflammatory Bowel Disease), IBD, IBD - Inflammatory Bowel Disease, Pregnancy
- Trial name
- CALINA-IBD (NCT07385807)
- Where
- 2 sites in Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Inflammatory Bowel Diseases, Ulcerative Colitis
Health-related Physical Fitness in Patients with Inflammatory Bowel Disease
Rationale: Existing literature suggests an impaired health-related physical fitness (HRPF) (i.e., body composition, aerobic capacity, muscular strength, muscular endurance, and flexibility) in patients with inflammatory bowel…
- Conditions
- Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
- Trial name
- NCT05482932
- Testing
- Health-related physical fitness assessment
- Where
- Netherlands
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Stomatitis
Using Tea-based Mouthwash Relieve Stomatitis and Oral Ulcers
The aim of this study is to use a tea-based mouthwash to relieve pain and discomfort in patients with stomatitis and ulcers.
- Trial name
- NCT05010928
- Testing
- mouthwash with tea
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Irritable Bowel Syndrome, Ulcerative Colitis
Phenotyping IBS: Perceptions and Modulations of Visceral Sensations
The purpose of this research study is to improve the understanding of irritable bowel syndrome (IBS) and its underlying cause. The investigators will use magnetic resonance imaging (MRI) to observe differences in the brain…
- Conditions
- Irritable Bowel Syndrome, Ulcerative Colitis, Inflammatory Bowel Disease
- Trial name
- PMVS-P (NCT02693730)
- Where
- United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Diabetes
Happier Feet- A Smart Insole for Diabetic Foot Ulceration Prevention
This study aims to design, develop, and evaluate a smart insole to predict the formation of diabetic foot ulcers (DFUs) in diabetic participants at risk of developing them.
- Trial name
- Happier Feet (NCT05865353)
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Ulcerative Colitis
Fecal Microbiota Transplantation as a Treatment for Ulcerative Colitis
Ulcerative colitis (UC) is characterized by a disrupted homeostasis of the commensal bacterial population (dysbiosis). A promising therapy for restoration of the altered balance of the enteric microbiota is fecal microbial…
- Trial name
- NCT04434872
- Testing
- Colonoscopy, Gastroscopy, Fecal Microbiota
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Osteoarthritis
A Study Of The Effect Of CJ-023,423 On The Incidence Of Stomach Ulcers
CJ-023,423 is a new medication being developed as an anti-inflammatory agent for the treatment of the signs and symptoms of osteoarthritis (OA).
- Trial name
- NCT00392080
- Testing
- CJ-023,423, naproxen
- Where
- 11 sites in United States
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Pfizer
Oral Ulcer
The Effectiveness of Pasteurized Goat Milk in the Treatment of Childhood Oral Ulcer Diseases
Children with acute diseases with oral ulcers (not included PRESENTATIONS OF SLE, IBD or IMMUNOCOMPRMIZED STATES)will receive several doses (drinking or mouth rinsing) of either pasteurized goat milk or cow milk.
- Trial name
- NCT00333749
- Testing
- Drinking or rinsing the mouth 2-3 times for 1 day, Pasturlized cow milk
- Where
- Israel
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
IBD (Inflammatory Bowel Disease)
E-nose in Evaluating Colitis Activity
The goal of this observational study is to learn whether a rapid stool-based imaging test can help monitor inflammatory bowel disease (IBD) in children.
- Trial name
- SPECTROS (NCT07781215)
- Testing
- Differential Mobile Spectrometry analysis of the stool
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Inflammatory Bowel Disease, Crohn Disease
The Role of IGRA in Screening and Monitoring for TB During Anti TNF Therapy in Patients With IMID
Hong Kong is a region of intermediate TB burden, and the reactivation of latent TB in IMID patients treated with anti-TNF can be a serious problem.
- Conditions
- Inflammatory Bowel Disease, Crohn Disease, Ulcerative Colitis, Tuberculosis
- Trial name
- IGRA (NCT02135289)
- Where
- Hong Kong
- Volunteers
- 9,160 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong