Clinical trials: Ulcers
Pressure Ulcer
Knowledge and Practices of Preventing Pressure Ulcers
Pressure ulcer is defined by the European Pressure Ulcer Advisory Panel (EPUAP) and the National Pressure Ulcer Advisory Panel (NPUAP) as "localized skin and/or skin, usually arising over bony prominences, caused by pressure…
- Trial name
- NCT05123417
- Testing
- Follow up
- Where
- Cyprus
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
IBD, Immunology
Immunological Profiles in Inflammatory Bowel Disease
Inflammatory Bowel Diseases (IBD) is a heterogeneous group of diseases regarding clinical presentation, disease course and treatment response.
- Conditions
- IBD, Immunology, Crohn Disease, Ulcerative Colitis
- Trial name
- ImmunoIBD (NCT03366090)
- Testing
- Biopsies during coloscopy
- Where
- Netherlands
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Rijnstate Hospital
Diabetic Foot Ulcers
Safety Study of Topical Human FGF-1 for Wound Healing
The purpose of the study is to see if FGF-1 is safe when applied topically to the surface of a wound.
- Trial name
- NCT00916292
- Testing
- FGF-1 141
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Phage Pharmaceuticals, Inc.
Inflammatory Bowel Diseases, Crohn Disease
Assessment of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ATH-063 in Healthy Subjects
The goal of this clinical trial is to test the ATH-063 drug (single and multiple doses) in Healthy Subjects. The clinical trial aims to evaluate the below. 1. Safety of the drug 2. Tolerability of the drug 3.
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis, Autoimmune Diseases
- Trial name
- NCT05807971
- Testing
- ATH-063
- Where
- Australia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Athos Therapeutics Inc
Ulcerative Colitis
Fecal Microbiota Transplantation (FMT) for Treatment of Ulcerative Colitis in Children
Patients diagnosed with ulcerative colitis (UC), a specific type of inflammatory bowel disease, will be invited to take part in this study. The investigators do not know what causes UC.
- Trial name
- FMT (NCT01947101)
- Testing
- Fecal Microbiota Transplant
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Pressure Ulcers, Nursing Students
The Effect of Pressure Ulcer Management Program Applied With Jigsaw Technique
The aim of this study is to evaluate the effectiveness of the jigsaw method on pressure ulcer prevention in senior nursing students. In addition, the study will also examine student views on the jigsaw technique.
- Conditions
- Pressure Ulcers, Nursing Students, Training Effectiveness, Randomized Controlled Trial
- Trial name
- NCT06899282
- Testing
- Jigsaw method, The theoretical training
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Neurotrophic Ulcer, Neurotrophic Keratitis
OCT Evaluation of Neurotrophic Ulcer Following Treatment With Oxervate
Neurotrophic keratitis (NK) is a condition where the cornea, or clear outer covering of the eye, has reduced sensation due to a variety of reasons.
- Conditions
- Neurotrophic Ulcer, Neurotrophic Keratitis, Neurotrophic Corneal Ulcer, Neurotrophic Keratoconjunctivitis
- Trial name
- NCT04573647
- Testing
- Cenegermin-Bkbj 0.002% Ophthalmic Solution [OXERVATE]
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sight Medical Doctors PLLC
Inflammatory Bowel Disease, Crohn Disease
Vascular Dysfunction in Paediatric IBD
Inflammatory Bowel Diseases (IBD) is a group of relapsing and remitting gut inflammatory conditions acquired due to genetic susceptibility and/or environmental triggers.
- Conditions
- Inflammatory Bowel Disease, Crohn Disease, Ulcerative Colitis
- Trial name
- NCT02161640
- Where
- United Kingdom
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Ulcerative Colitis
The Role of CD4+ T Cell Subsets in the Mechanism of Action of Vedolizumab in Ulcerative Colitis
The cause of Inflammatory Bowl Disease (IBD) is not known, but studies from patients with IBD have found that these patients make unusually strong immune responses to their own intestinal tissues and to bacteria that normally…
- Trial name
- NCT02721719
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Diabetic Foot Ulcer, Ulcer Foot
Bioresorbable Glass Fiber Matrix in the Treatment of Diabetic Foot Ulcers
This study is a prospective, multi-center, randomized controlled trial designed to collect patient outcome data on 2 commercially available treatments for diabetic foot wounds.
- Conditions
- Diabetic Foot Ulcer, Ulcer Foot, Diabetic Foot
- Trial name
- NCT06403605
- Testing
- Mirragen Advanced Wound Matrix, Fibracol
- Where
- 15 sites in United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- ETS Wound Care, LLC
Ulcerative Colitis
Safety, Tolerability and Pharmacokinetics of Oral NX-13 in Healthy Adults Male and Female Volunteers
This is a randomized, double-blind, placebo-controlled, ascending dose, multi-cohort study. The study will be conducted in 2 parts: a single ascending dose (SAD) part (Part A) followed by a multiple ascending dose (MAD) part…
- Trial name
- NCT04458805
- Testing
- NX-13 250 mg
- Where
- Australia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Landos Biopharma Inc.
Ulcerative Colitis
Effect of Probiotic Supplementation on the Immune System in Patients With Ulcerative Colitis in Amman, Jordan
Ulcerative colitis (UC) is a chronic Inflammatory bowel disease (IBD) that most likely results from the interaction between various environmental and genetic factors.
- Trial name
- NCT04223479
- Testing
- Probiotic Formula Capsule
- Where
- Jordan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Inflammatory Bowel Diseases
Autonomic and Cytokines Profiles of Patients With Ulcerative Proctitis
1. To prove that patients with ulcerative proctitis and proctosigmoiditis have impaired autonomic functions, i.e. increased sympathetic activity and/or reduced vagal tone. 2.
- Trial name
- NCT03259659
- Testing
- ECG recording, inflammatory cytokines, microbiota, ulcerative colitis disease activity index
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Oral Mucositis, ORAS
Combination of Diclofenac Potassium and Propolis in the Therapy of Oral Aphthosis
The combination of diclofenac and propolis could enhance the healing of recurrent aphthous ulcers, instantly relieve symptoms, improve the quality of life, and present a de novo and cost-effective regime help in oral ulcer…
- Conditions
- Oral Mucositis, ORAS, Oral Infection, Oral Ulcer
- Trial name
- NCT05413096
- Testing
- Combination of diclofenac potassium and propolis
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Diabetic Foot Ulcer
Improving DFU Outcomes: Early Detection of Foot Ulcers Using Novel Technology
The investigator team will study the adherence of the participant cohort to a non significant risk device over a six month period.
- Trial name
- DFUMAT (NCT05968924)
- Testing
- Podimetrics SmartMat
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Fall, Pressure Ulcer
PROSENIOR. Prevention of Pressure Ulcers, Malnutrition, Poor Oral Health and Falls Among Older Persons Receiving Municipal Health Care and Are Registered in the Quality Registry Senior Alert
Inclusion criteria for study I and II is nurse aides, registered nurses and managers working in nursing homes who register in Senior Alert.
- Conditions
- Fall, Pressure Ulcer, Malnutrition, Oral Health
- Trial name
- NCT05308862
- Testing
- Care process for assessements of risks
- Where
- Sweden
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Malmö University
Diabetic Foot Ulcer, Self Care
Diabetic Foot Self Care
The scale, whose validity and reliability were examined in the study, consists of 26 items. The study sample consisted of 202 individuals with diabetes.
- Conditions
- Diabetic Foot Ulcer, Self Care, Nursing Care
- Trial name
- NCT07572188
- Testing
- Self-Care Tool for Diabetic Foot Prevention
- Where
- Turkey (Türkiye)
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Venous Stasis Ulcers
A Post Marketing Clinical Study Utilizing DermaStream and Saline in Venous Ulcers
An open-label, prospective, controlled, two-step approach, post-marketing clinical study, applying DermaStream with saline streaming, in conjunction with a sustained multi-compression wrap, on healthy individuals and on patients…
- Trial name
- NCT01129986
- Testing
- DermaStream
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- EnzySurge
Heartburn, Acid-dependent Diseases of the Gastrointestinal Tract
Comparative Pharmacodynamics and Pharmacodynamics Equivalence of Antareit 800 mg/10 ml Oral Suspension and Riopan 800 mg Chewable Tablets in Healthy Volunteers
Comparative study of the pharmacodynamic parameters and pharmacodynamic equivalence (bioequivalence) of drug Antareit 800 mg/10 ml oral suspension and drug Riopan 800 mg chewable tablets in healthy volunteers.
- Conditions
- Heartburn, Acid-dependent Diseases of the Gastrointestinal Tract, Symptomatic Treatment of Gastric and Duodenal Ulcers
- Trial name
- NCT06098742
- Testing
- Antareit
- Where
- 2 sites in Russia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Valenta Pharm JSC
Irritable Bowel Syndrome, Inflammatory Bowel Disease (IBD)
Cognition and Emotion in the SII and IBD
The study aims at showing that the susceptibility in the stress is more raised at the person affected digestive pathologies (SII or IBD) in forgiveness than healthy subjects.
- Conditions
- Irritable Bowel Syndrome, Inflammatory Bowel Disease (IBD), Crohn's Disease(CD), Ulcerative Colitis
- Trial name
- EMOTION (NCT01095042)
- Testing
- emotion
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble