Clinical trials: Umbilical Cord
Safety Issues, Effect of Drugs
The Treatment of Premature Infants With Brain Injury by Autologous Umbilical Cord Blood Stem Cells
To study the safety and effect of autologous umbilical cord blood stem cells for treatment brain injury
- Trial name
- NCT03696745
- Testing
- autologous umbilical cord blood stem cells, 0.9% Sodium-chloride
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Guangdong Women and Children Hospital
Regenerative Medicine, Stem Cell Banking
Comparative Study of Perinatal Tissues for Clinical-Grade Mesenchymal Stem Cell Production and Cost-Effectiveness
This observational laboratory-based study was conducted to evaluate the clinical feasibility and cost-effectiveness of mesenchymal stem cell (MSC) production from perinatal medical waste, including umbilical cord, amniotic fluid…
- Conditions
- Regenerative Medicine, Stem Cell Banking, Perinatal Medical Waste, Umbilical Cord Stem Cells
- Trial name
- NCT07169838
- Testing
- Perinatal Tissue Collection
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Iron-deficiency Anemia
Umbilical Cord Clamping and Infant Iron Status
The aim of the study was to determine whether delayed umbilical cord clamping, as compared to early umbilical cord clamping, improves infant iron status at 6 months of age.
- Trial name
- NCT00298051
- Testing
- Delayed umbilical cord clamping
- Where
- Mexico
- Volunteers
- 476 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Infection
Impact of Chlorhexidine Cleansing on Bacteria Colonizing the Umbilical Cord of Infants in Bangladesh
Background: In developing countries, many babies are born at home and the umbilical cord commonly becomes infected during the first week after birth, and can be deadly.
- Trial name
- NCT00719329
- Testing
- Chlorhexidine 4.0%, Dry Cord Care
- Where
- 3 sites in United States, Bangladesh
- Volunteers
- 1,931 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Anemia, Ferritin
Effect of Timing of Umbilical Cord Clamping on Haematological and Clinical Outcomes of Infants
In developing countries up to 50% of children become anemic by 12 months of age(1. Iron deficiency anemia is a major risk factor for neonatal and infantile mortality and morbidity in Pakistan.
- Conditions
- Anemia, Ferritin, Complications, Hemorrhage
- Trial name
- NCT01081977
- Testing
- Early Cord Clamping, Delayed Cord Clamping
- Where
- Pakistan
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Cord Blood Stem Cell Transplantation, Cord Blood Transplantation
The Collection and Storage of Umbilical Cord Blood for Transplantation
The goal of this study is to collect blood samples from the umbilical cords of newborn babies, as soon as they are delivered, and to place these samples in the MD Anderson Cord Blood Bank.
- Conditions
- Cord Blood Stem Cell Transplantation, Cord Blood Transplantation, Hematopoietic Stem Cell Transplantation
- Trial name
- NCT01728545
- Where
- United States
- Volunteers
- 250,000 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Patient Comfort, Postpartum Hemorrhage
The Effect of Skin-to-skin Contact on Placental Separation Time, Type, Postpartum Hemorrhage and Comfort
It is aimed to determine the late cord clamping with early skin-to-skin contact in primiparous pregnant women who delivered vaginally, according to placental separation time, separation method, amount of postpartum bleeding and…
- Conditions
- Patient Comfort, Postpartum Hemorrhage, Midwifery, Placenta
- Trial name
- NCT06011096
- Testing
- skin-to-skin contact and delayed cord clamping, avoiding skin-to-skin contact and early cord clamping
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Bahar GÖBEL
Pregnancy Related, Umbilical Cord Issue
Association Between Blood Volume, the Interval From Delivery to Cord Clamping, and Number of Umbilical Cord Milking
Delayed umbilical cord clamping (DCC), usually 1-3 minutes, is reported to be beneficial for term and preterm infants. Nevertheless, there are reasons that urge us to reevaluate the effect of DCC.
- Conditions
- Pregnancy Related, Umbilical Cord Issue, Placental Transfusion
- Trial name
- NCT04898868
- Testing
- cord blood spontaneous drainage, Umbilical cord miking
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Health Status Unknown
Studying Umbilical Cord Blood From African-American Donors
RATIONALE: Studying umbilical cord blood in the laboratory and gathering information about current and previous pregnancies from African-American umbilical cord blood donors may help doctors learn more about the umbilical cord…
- Trial name
- NCT00717535
- Testing
- cryopreservation, questionnaire administration, study of socioeconomic and demographic variables
- Volunteers
- healthy volunteers welcome
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Pregnancy
Expansion of Umbilical Cord Blood Using a Unique Bio-system
By doing this study, researchers hope to develop a special technique and laboratory conditions to help support umbilical stem cell growth and multiplication.
- Trial name
- NCT01061879
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Knee Osteoarthritis, Umbilical Cord Bleeding
The Maximum Tolerated Dose of Mesenchymal Stem Cells From Umbilical Cord
The aim of this study was to evaluate the maximum tolerated dose of Mesenchymal Stem Cells (MSCs) from umbilical cord in the treatment of human knee OA
- Trial name
- NCT03357770
- Testing
- mesenchymal stem cells
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Traumatic Brain Injury
Effects of Intravascular Administration of Mesenchymal Stromal Cells Derived from Wharton's Jelly of the Umbilical Cord on Systemic Immunomodulation and Neuroinflammation After Traumatic Brain Injury.
Traumatic brain injuries (TBI) are one of the leading causes of death and disability worldwide. These patients are burdened by physical, cognitive, and psychosocial deficits, leading to an important economic impact for society.
- Trial name
- TRAUMACELL (NCT06146062)
- Testing
- Mesenchymal Stromal Cells (MSC)
- Where
- 3 sites in France
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Newly Diagnosed Type 1 Diabetes Mellitus
UCMSCs Combined With Standard Therapy for the Treatment of Newly Diagnosed Type 1 Diabetes
The aim is to investigate the safety and tolerability of intravenous infusion of allogeneic umbilical cord mesenchymal stem cells in pediatric patients diagnosed with newly onset type 1 diabetes
- Trial name
- NCT06407297
- Testing
- UCMSCs
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Shanghai Changzheng Hospital
Newborn; Infection, Umbilical Cord Infection
The Effect of Umbilical Cord Clamping Distance
A randomized control trial was conducted to test the effect of umbilical cord clamping distance on cord separation time and umbilical cord microbial colonization in neonates.
- Trial name
- NCT04862403
- Testing
- Umbilical cord clamping distance
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Rectal Injury
A Study of TH-SC01 in the Treatment of Radiation-induced Rectal Injury
The purpose of this study is to evaluate the efficacy and safety of allogeneic umbilical cord mesenchymal stem cells in the treatment of radiation-induced rectal injury.
- Trial name
- NCT05939778
- Testing
- TH-SC01(Umbilical cord mesenchymal stem cells)
- Where
- China
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Jinling Hospital, China
Diabetes
UCMSCs Combined With Allogeneic Islet Transplantation for the Treatment of Diabetes
The aim is to Investigate the safety and efficacy of Portal vein infusion Allogeneic Human umbilical cord mesenchymal stem cells combined with Allogeneic islet transplantation for the treatment of diabetes
- Trial name
- NCT06751199
- Testing
- human umbilical cord mesenchymal stem cells, allogeneic islet
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Shanghai Changzheng Hospital
Preterm Premature Rupture of Membranes
Matrix Metalloproteinase 14, Neopterin, and Orosomucoid 1 Levels in PPROM
Introduction: To evaluate the maternal blood serum matrix metalloproteinase 14, neopterin, and orosomucoid 1 levels in pregnant women complicated by preterm premature rupture of membranes (PPROM) and to compare the results with…
- Trial name
- MMP-14&PPROM (NCT04532021)
- Testing
- matrix metalloproteinase 14, neopterin, and orosomucoid 1 measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Cengiz Gokcek Women's and Children's Hospital
Umbilical Cord Infection, Newborn
Dry Cord Care Versus Alcohol Cord Care in Healthy Newborns
Umbilical cord care is an essential component of newborn care, but the optimal method remains controversial. This randomized controlled trial aims to compare routine alcohol cord care with natural dry cord care in healthy…
- Trial name
- NCT07728058
- Testing
- Routine Alcohol Cord Care, Natural Dry Cord Care
- Where
- Taiwan
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Group B Streptococcus
Oral Penicillin and Penicillin Levels in Venous Umbilical Cord Blood
Pregnant,laboring women will receive 2 grams of oral penicillin V before delivery. At the time of delivery of the infant, umbilical vein cord blood will be obtained from the umbilical cord.
- Trial name
- NCT00823433
- Testing
- oral penicillin V
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Birth Weight, Fetal Body Weight
Cross Sectional Area of Umbilical Cord Versus Hadlock's Formula in Prediction of Neonatal Birth Weight
Ultrasound measurement of cross sectional area of umbilical cord might offer advantage over Hadlock's formula for accurate estimation of actual birth weight at term gestation leading to prevention of large number of maternal and…
- Trial name
- NCT05362175
- Testing
- Obstetric ultrasound
- Where
- Egypt
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Ain Shams University