Clinical trials: Umbilical Cord
Pregnancy
Expansion of Umbilical Cord Blood Using a Unique Bio-system
By doing this study, researchers hope to develop a special technique and laboratory conditions to help support umbilical stem cell growth and multiplication.
- Trial name
- NCT01061879
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Regenerative Medicine, Stem Cell Banking
Comparative Study of Perinatal Tissues for Clinical-Grade Mesenchymal Stem Cell Production and Cost-Effectiveness
This observational laboratory-based study was conducted to evaluate the clinical feasibility and cost-effectiveness of mesenchymal stem cell (MSC) production from perinatal medical waste, including umbilical cord, amniotic fluid…
- Conditions
- Regenerative Medicine, Stem Cell Banking, Perinatal Medical Waste, Umbilical Cord Stem Cells
- Trial name
- NCT07169838
- Testing
- Perinatal Tissue Collection
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Difficult to Healing of Skin Ulcers
UC-MSCs Gel Treatment Difficult Healing of Skin Ulcers
This study for a six-month trials, Randomized, open, and parallel comparison before and after its own, Stage test includes screening stage, treatment period and follow-up period.
- Trial name
- UC-MSCs (NCT02685722)
- Testing
- UC-MSCs Gel group, Gel group
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Uterine Scar
Safety of Umbilical Cord Mesenchymal Stem Cell Local Intramuscular Injection for Treatment of Uterine Scars
The purpose of this study is to evaluate the safety of umbilical cord mesenchymal stem cell local intramuscular injection for treatment of uterine scars by a prospective, single-center, open, and single-arm clinical trial.
- Trial name
- NCT03181087
- Testing
- Umbilical cord MSCs
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Foshan
Rectal Injury
A Study of TH-SC01 in the Treatment of Radiation-induced Rectal Injury
The purpose of this study is to evaluate the efficacy and safety of allogeneic umbilical cord mesenchymal stem cells in the treatment of radiation-induced rectal injury.
- Trial name
- NCT05939778
- Testing
- TH-SC01(Umbilical cord mesenchymal stem cells)
- Where
- China
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Jinling Hospital, China
Caesarean Delivery
Regenerative Effects of Birth Material Derived Extracellular Vesicles
Stem cells offer great hope for a wide range of disorders, including age-related brain disease such as dementia. Mesenchymal stem cells (MSCs) are special types of adult stem cells found in various tissues like the umbilical…
- Trial name
- ReGAIN (NCT06866184)
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Umbilical Cord
Assessment of the Number of Umbilical Cord Vessels at the Time of Nuchal Translucency Screening
The primary objective of this study is to determine the detection rate of two- or three-vessel umbilical cord at the time of nuchal translucency screening between 11 and 13 6/7 weeks gestation.
- Trial name
- NCT01367132
- Testing
- Doppler ultrasound
- Where
- 2 sites in United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Stroke
Umbilical Cord Derived Mesenchymal Stem Cells Treatment in Ischemic Stroke
The study aims at estimating the safety and efficacy of the intravenous injection of human umbilical cord mesenchymal stem cell(hUC-MSC) for patients suffering from ischemic stroke in recent 3 months.
- Trial name
- Recruiting (NCT02580019)
- Testing
- Human umbilical cord mesenchymal stem cells
- Where
- China
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Cord Clamping
Timing of Umbilical Cord Clamping in Preterm Neonates
Umbilical cord clamping is an important intervention that routinely done for all neonates afterbirth. yet the optimal timing for this intervention remains controversial
- Trial name
- NCT06000800
- Testing
- Group B, Group C, Group D
- Where
- Egypt
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pregnancy, Pregnancy in Diabetes
Exploration of the Lipid Metabolism During the Diabetic Pregnancies
Justification: Intrauterine exposure to type 1 or type 2 diabetes increase the risk of macrosomia (35 % to 50 % versus 10 % in general population) despite a good glycemic control.
- Conditions
- Pregnancy, Pregnancy in Diabetes, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
- Trial name
- DIAMANT (NCT00639964)
- Testing
- blood tests, diet questionnaire, umbilical cord blood collect
- Where
- France
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Umbilical Cord
Timing of Umbilical Cord Clamping: One to Three Minutes vs. After Cessation of Cord Pulsation
The timing of umbilical cord clamping has been widely discussed in the scientific community. As part of the worldwide strategies to reduce childhood iron deficiency anemia, the incorporation of late clamping (at least one minute…
- Trial name
- CORD (NCT03844490)
- Testing
- CESSATION OF CORD PULSE, CONTROL
- Where
- Brazil
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Newly Diagnosed Type 1 Diabetes Mellitus
UCMSCs Combined With Standard Therapy for the Treatment of Newly Diagnosed Type 1 Diabetes
The aim is to investigate the safety and tolerability of intravenous infusion of allogeneic umbilical cord mesenchymal stem cells in pediatric patients diagnosed with newly onset type 1 diabetes
- Trial name
- NCT06407297
- Testing
- UCMSCs
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Shanghai Changzheng Hospital
Umbilical Cord Bleeding, Knee Osteoarthritis
Evaluating Safety and Efficacy of Mesenchymal Stem Cells From Umbilical Cord
This study was to evaluate the safety and efficacy of Mesenchymal Stem Cells (MSCs) from umbilical cord in the treatment of 7 knee OA patients by assessing unexplained local and systemic symptoms or death before and at 1, 2, 3, 6…
- Trial name
- NCT03358654
- Testing
- mesenchymal stem cells from umbilical cord
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Knee Osteoarthritis, Umbilical Cord Bleeding
The Maximum Tolerated Dose of Mesenchymal Stem Cells From Umbilical Cord
The aim of this study was to evaluate the maximum tolerated dose of Mesenchymal Stem Cells (MSCs) from umbilical cord in the treatment of human knee OA
- Trial name
- NCT03357770
- Testing
- mesenchymal stem cells
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Iron Deficiency, Neonatal Hyperbilirubinemia
Early Versus Delayed Cord Clamping at Term: Outcomes in Swedish Infants
Delayed clamping of the umbilical cord might prevent or slow the onset of iron deficiency by increasing the infant's iron endowment at birth.
- Trial name
- NCT01245296
- Testing
- Timing of clamping the umbilical cord
- Where
- Sweden
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Newborn Morbidity, Newborn Complication
Cord Blood Preptin Levels in Infants
In this study, cord blood preptin levels in infants with high or low birth weight will be compared to those in infants with normal birth weight.
- Trial name
- NCT06880003
- Testing
- During delivery, blood samples will be collected from the umbilical cord
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Microbial Colonization
Non-caloric Sweeteners Levels in Breast Milk and Newborn's Blood and Effect on Microbiota's Composition.
This study evaluates the presence and quantity of non-caloric sweeteners in newborns umbilical cord blood, and in their mother's breast milk at delivery, at 2 months, 4 months and 6 months of age.
- Trial name
- NCT03912038
- Testing
- No intervention.
- Where
- Mexico
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Hospital General de México Dr. Eduardo Liceaga
Orthopedic Disorder, Neurologic Disorder
Safety and Clinical Outcomes With Amniotic and Umbilical Cord Tissue Therapy for Numerous Medical Conditions
To determine the safety and efficacy of Amniotic and Umbilical Cord Tissue for the treatment of the following condition categories: Orthopedic, Neurologic, Urologic, Autoimmune, Renal, Cardiac and Pulmonary Conditions.
- Conditions
- Orthopedic Disorder, Neurologic Disorder, Urologic Diseases, Erectile Dysfunction
- Trial name
- NCT03899298
- Testing
- Amniotic and Umbilical Cord Tissue Procedure
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- R3 Stem Cell
Delayed Cord Clamping, Umbilical Cord Milking
The Hematologic Impact of Umbilical Cord Milking Versus Deferred Cord Clamping in Premature Neonates.
Comparing the beneficial effect of cord milking versus deferred cord clamping in preterm neonates. A randomized controlled trial
- Conditions
- Delayed Cord Clamping, Umbilical Cord Milking, Preterm Neonates
- Trial name
- NCT03147846
- Testing
- delayed cord clamping, cord milking
- Where
- Saudi Arabia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Diabetes in Pregnancy
Telocytes in Placental Tissues of Patients With Gestational and Pre-gestational Diabetes
Examining the expression of telocytes in the placental tissues and umbilical cord of patients with gestational or pregestational diabetes during pregnancy compared to control.
- Trial name
- NCT05305326
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University