Clinical trials: Umbilical Cord
Pregnant Women
microRNA Profile in Umbilical Cord Blood NK Cells
Umbilical cords contain immature blood cells, including a group of lymphocytes, that are important in the so-called natural immunity.
- Trial name
- NCT00751569
- Testing
- blood donation
- Where
- Taiwan
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Delayed Umbilical Cord Clamping Benefits, Postpartum Haemorrhage
Timing of Umbilical Cord Occlusion in Premature Babies( <33 w). Delayed vs Early.
Early cord clamping after delivery has been common practice for many decades as part of the active management of the third stage of labour.
- Conditions
- Delayed Umbilical Cord Clamping Benefits, Postpartum Haemorrhage, Intraventricular Haemorrhage
- Trial name
- CODE-P (NCT02187874)
- Testing
- delayed umbilical cord occlusion, early umbilical cord occlusion, Oxytocin
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Microbial Colonization, Antibiotic Side Effect
Timing of Maternal Antibiotic Prophylaxis During a Cesarean Section and the Early Infant Gut Microbiome
In this study, investigators seek to determine whether the timing of antibiotics given to mothers during an elective C-section affects the composition of their infant's gut microbiome.
- Conditions
- Microbial Colonization, Antibiotic Side Effect, Cesarean Section Complications
- Trial name
- CSBabyBiome (NCT06030713)
- Testing
- Cefazolin
- Where
- Netherlands
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Umbilical Cord Blood, Cesarean Section Surgery
Effect of Delivery Time on Umbilical Cord Blood Gas Parameters in Cesarean Sections Under General and Spinal Anesthesia
The goal of this observational study is to evaluate the effect of neonatal delivery time on umbilical cord blood gas parameters in pregnant women undergoing elective cesarean section under general or spinal anesthesia.
- Conditions
- Umbilical Cord Blood, Cesarean Section Surgery, General Anesthesia, Spinal Anesthesia
- Trial name
- DELTA-CS (NCT07321041)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Pregnancy Related, Umbilical Cord Issue
Association Between Blood Volume, the Interval From Delivery to Cord Clamping, and Number of Umbilical Cord Milking
Delayed umbilical cord clamping (DCC), usually 1-3 minutes, is reported to be beneficial for term and preterm infants. Nevertheless, there are reasons that urge us to reevaluate the effect of DCC.
- Conditions
- Pregnancy Related, Umbilical Cord Issue, Placental Transfusion
- Trial name
- NCT04898868
- Testing
- cord blood spontaneous drainage, Umbilical cord miking
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Umbilical Cord Infection, Newborn
Dry Cord Care Versus Alcohol Cord Care in Healthy Newborns
Umbilical cord care is an essential component of newborn care, but the optimal method remains controversial. This randomized controlled trial aims to compare routine alcohol cord care with natural dry cord care in healthy…
- Trial name
- NCT07728058
- Testing
- Routine Alcohol Cord Care, Natural Dry Cord Care
- Where
- Taiwan
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Premature Birth
Delayed Umbilical Cord Clamping in Infants Less Than 32 Weeks
The overall objective of the present study is to examine the effects of delayed umbilical cord clamping in preterm infants on neonatal outcomes using a prospective randomized controlled trial comparing immediate cord clamping…
- Trial name
- DUC (NCT00562536)
- Testing
- Umbilical cord clamping
- Where
- Canada
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Leukemia, Lymphoma
Centralized Cord Blood Registry to Facilitate Unrelated Cord Blood Transplantation
The National Marrow Donor Program (NMDP) has established a system for registering, matching, and tracking unrelated donor cord blood units (CBUs) and transplant outcomes.
- Conditions
- Leukemia, Lymphoma, Myelodysplastic Syndromes
- Trial name
- NCT00737516
- Testing
- HPC, Cord Blood
- Where
- 19 sites in United States
- Volunteers
- 3,621 people, healthy volunteers welcome
- Sponsor
- National Marrow Donor Program
Neonatal Mortality
Community Trial of Newborn Skin and Umbilical Cord Cleansing on Neonatal Mortality in Nepal
Neonatal mortality and morbidity is common in Nepal and the vast majority of women deliver babies at home without a skilled birth attendant.
- Trial name
- NCT00109616
- Testing
- Newborn skin cleansing with 0.25% chlorhexidine solution, Cleansing of umbilical cord with soap and water solution, Cleansing of umbilical cord with 4% chlorhexidine
- Where
- 2 sites in United States, Nepal
- Volunteers
- 17,000 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Gingival Recession, Localized
Reconstruction of Deficient Interdental Papilla Using Stem Cells vs Physiological Saline
The goal of this study is to assess the reconstruction of interdental papilla following the injection of UC-MSCs or physiological saline in patients with interdental papilla deficiency.
- Trial name
- NCT06388447
- Testing
- Umbilical cord-mesenchymal stem cells
- Where
- Malaysia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Health Status Unknown
Studying Umbilical Cord Blood From African-American Donors
RATIONALE: Studying umbilical cord blood in the laboratory and gathering information about current and previous pregnancies from African-American umbilical cord blood donors may help doctors learn more about the umbilical cord…
- Trial name
- NCT00717535
- Testing
- cryopreservation, questionnaire administration, study of socioeconomic and demographic variables
- Volunteers
- healthy volunteers welcome
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Third Stage of Labor, Healthy
Impact of Umbilical Cord Clamping Time on Infant Anemia
This research was conducted to carry out the effect of umbilical cord clamping time on baby anemia.
- Conditions
- Third Stage of Labor, Healthy, Umbilical Cord Clamping Time, Infant Conditions
- Trial name
- NCT04463485
- Testing
- Delayed Clamping
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Mersin University
Umbilical Cord; Clamping Time
The Effect of Delayed Cord Clamping and Milking on the Amount of Stem Cells In Preterm
Stem cell therapies have been promising therapies in neonatal morbidities such as bronchopulmonary dysplasia, intraventricular hemorrhage and hypoxic ischemic encephalopathy.
- Trial name
- NCT04057027
- Testing
- Delayed umbilical cord clamping, Cord Milking
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Umbilical Cord Management, Elective Cesarean Section
Delayed Cord Clamping in Infants Born by Cesarean Section
Introduction: Placental transfusion supports an important blood transfer to the neonate, promoting a more stable and smooth transition from fetal to extra-uterine life.
- Trial name
- NCT03549884
- Testing
- Delayed cord clamping, Early cord clamping
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova
Group B Streptococcus
Oral Penicillin and Penicillin Levels in Venous Umbilical Cord Blood
Pregnant,laboring women will receive 2 grams of oral penicillin V before delivery. At the time of delivery of the infant, umbilical vein cord blood will be obtained from the umbilical cord.
- Trial name
- NCT00823433
- Testing
- oral penicillin V
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Umbilical Cord of Normal Labor
CD49 in Optimization The Cologenicity of Mesenchymal Stem Cell Culture Passage
Human mesenchymal stem cells (MSCs) due to their regenerative and immunomodulatory properties are widely used for the treatment of bone and cartilage damage, cardiovascular, gastrointestinal, autoimmune, neurodegenerative…
- Trial name
- NCT05093725
- Testing
- flow cytomery
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sohag University
Pregnant, Healthy Females, Healthy Male Newborns
Use of Existing Fibroblast Cells to Convert to Induced Pluripotent Stem Cells
Induced pluripotent stem cells potentially may be useful in the future as an unlimited source of cells for transplantation. The major goal of the project is to develop human iPS cells from existing lines of fibroblasts that were…
- Trial name
- NCT00801372
- Where
- Israel
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Effects of a Cord Clamping Bundle on Maternal and Neonatal Outcomes
"The Effect of the Cord Clamping Bundle at Birth Developed With the Delphi Method on Maternal and Newborn Outcomes"
This clinical trial aims to evaluate the effects of a cord clamping bundle developed through the Delphi method on maternal and neonatal outcomes.
- Trial name
- Cord Clamping (NCT07701434)
- Testing
- Cord Clamping Bundle, Routine Cord Clamping Care
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Elif MARANGOZ
Skin Wound, Scar, Hypertrophic
Umbilical Cord Stem Cells for Skin Grafts in Donor Site Wounds
The goal of this clinical trial is to evaluate the safety and effectiveness of human umbilical cord mesenchymal stem cell (hUCMSC) therapy in patients undergoing medium-thickness skin grafts for donor site wounds.
- Trial name
- NCT05984628
- Testing
- human umbilical cord mesenchymal stem cells, blank solvent
- Where
- China
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Lactic Acidemia
Amnioinfusion for Intrauterine Neuroprotection
Hypoxic ischemic encephalopathy (HIE), a serious brain injury in infants, occurs in 2-9 per 1,000 infants after delivery. Up to 60% of infants diagnosed with HIE die and 25% of the survivors have long-term neurologic deficits.
- Trial name
- NCT05513690
- Testing
- Amnioinfusion at room temperature (intervention arm)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island