Clinical trials: Umbilical Cord Blood
Intrauterine Retardation
Levels of Endocan in Umbilical Cord Blood Samples of Pregnant Females With Intrauterine Growth Retardation
As a proteoglycan secreted from endothelial cells, expression, and secretion of endocan increases in the endothelium of several tissues secondary to inflammation. It can be regarded as an indicator of endothelial damage.
- Trial name
- NCT04630223
- Testing
- endocan in umbilical cord blood
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Van Bölge Eğitim ve Araştırma Hastanesi
Safety Issues, Effect of Drugs
The Treatment of Premature Infants With Brain Injury by Autologous Umbilical Cord Blood Stem Cells
To study the safety and effect of autologous umbilical cord blood stem cells for treatment brain injury
- Trial name
- NCT03696745
- Testing
- autologous umbilical cord blood stem cells, 0.9% Sodium-chloride
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Guangdong Women and Children Hospital
Atopy
Predictors of Cord Blood Immunoglobin E (IgE) Levels
Background: Increased total serum IgE levels are a common characteristic of atopic diseases. Increased cord blood IgE levels, in conjunction with a family history of atopy, are associated with the development of allergic diseases…
- Trial name
- NCT00902096
- Where
- Taiwan
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Min-Sheng General Hospital
Type 1 Diabetes
Stem Cell Educator Therapy in Type 1 Diabetes
The translational potential to the clinical applications of cord blood stem cells has increased enormously in recent years, mainly because of its unique advantages including no risk to the donor, no ethical issues, low risk of…
- Trial name
- NCT01350219
- Testing
- Stem Cell Educator
- Where
- 4 sites in China, Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Throne Biotechnologies Inc.
Kidney Cancer
Studying Genes Using Cord Blood and Placenta Samples From Relatively Healthy Newborns and Samples From Younger Patients With Wilms Tumor
RATIONALE: Studying samples of blood and tissue from newborns and from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT01576211
- Testing
- DNA methylation analysis, RNA analysis, allele-specific oligonucleotide real-time quantitative polymerase chain reaction
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Children's Oncology Group
Umbilical Cord Blood
Performance Evaluation of the ex Utero Cord Blood Collection Technique: Procedure, Quality and Results
Umbilical cord blood (UCB) is used for leukemia patients and other serious blood disorders worldwide. (3) It has also been recently used for other therapeutic applications such as wound treatment, red blood cell transfusion, or…
- Trial name
- NCT05836974
- Testing
- Ex-utero cord blood collection, In-utero cord blood collection
- Where
- Spain
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Fundacion Dexeus
Vitamin A Deficiency
Retinol Status in Preterm Infants and Mothers
Retinol and retinol binding protein were studied in the umbilical cord blood of 44 preterm infants with gestation age of < 30 weeks. Serum retinol and RBP levels were determined by enzyme-linked immunosorbent assay.
- Trial name
- NCT04780958
- Testing
- Serum retinol and RBP levels were determined by enzyme-linked immunosorbent assay.
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Diphtheria, Hepatitis B
Pilot Study Freeze and Transport Immune Cells
To evaluate and standardize umbilical cord specimen collection and laboratory procedures to evaluate cellular and serological immune responses in neonates and young infants
- Conditions
- Diphtheria, Hepatitis B, Pertussis, Poliomyelitis
- Trial name
- NCT00138268
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Zinc Deficiency, Birth Length
Zinc Supplementation During Pregnancy: Analysis of Maternal Serum Zinc, Cord Blood Osteocalcin and Neonatal Birth Length
This experimental study was conducted with pre-test/post-test control groups and double-blind randomization from March to December 2019 at Universitas Sumatera Utara Hospital and others in Medan.
- Trial name
- NCT04559152
- Testing
- Zinc Supplementation Group
- Where
- Indonesia
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Universitas Sumatera Utara
Fetal Growth Retardation
Comparison of Pesticide and Pharmaceutical Contaminants Levels in Placenta and Cord Blood Samples of Pregnant Women With Fetal Growth Retardation and Healthy Pregnant Women
Aim: In this study, pesticide and pharmaceutical contaminants levels in the placenta and cord blood of pregnant women with fetal growth retardation and healthy pregnant women will be compared in placenta and cord blood samples…
- Trial name
- NCT05088148
- Testing
- . Pesticide and Pharmaceutical analysis
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Sweat Gland Diseases
Umbilical Cord Blood-derived Mesenchymal Stem Cells in Regeneration of Sweat Glands and Body Repair
Patients with skin injury treated with Umbilical Cord Blood-derived Mesenchymal Stem Cells,such as deep burn damaged sweat glands,Effectiveness of Umbilical Cord Blood-derived Mesenchymal Stem Cells in Regeneration of Sweat…
- Trial name
- NCT02304562
- Testing
- UCB Mesenchymal Stem Cells treatment
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Eye Injuries
Comparison of the Effects on Promoting Corneal Epithelial Wound Healing Between Human Auto-Serum and Cord Blood Serum
Human serum eye drops have been successfully used in the treatment of severe ocular surface disorders and the enhancement of corneal wound healing.
- Trial name
- NCT00598299
- Testing
- venous puncture, obtain serum from perripheral blood or cord blood
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Normal Full-Term Deliveries
Generation of Dendritic Cell Precursors From Cord Blood Stem Cells
There is a growing interest in generating dendritic cells (DCs) for using as vaccines. Several cytokines, especially stem cell factor (SCF) and FLT3-ligand (FL), have been identified as essential to produce large numbers of…
- Trial name
- NCT00731744
- Testing
- Normal full-term deliveries
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cord Blood Stem Cell Transplantation, Cord Blood Transplantation
The Collection and Storage of Umbilical Cord Blood for Transplantation
The goal of this study is to collect blood samples from the umbilical cords of newborn babies, as soon as they are delivered, and to place these samples in the MD Anderson Cord Blood Bank.
- Conditions
- Cord Blood Stem Cell Transplantation, Cord Blood Transplantation, Hematopoietic Stem Cell Transplantation
- Trial name
- NCT01728545
- Where
- United States
- Volunteers
- 250,000 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Pregnancy
Expansion of Umbilical Cord Blood Using a Unique Bio-system
By doing this study, researchers hope to develop a special technique and laboratory conditions to help support umbilical stem cell growth and multiplication.
- Trial name
- NCT01061879
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Gestational Diabetes, Pregestational Diabetes
Possible Epigenetic Changes in Offspring of Women With Pregestational and Gestational Diabetes
Pregestational diabetes (PGD) during pregnancy may be associated with an increased rate of spontaneous abortions, intrauterine death and congenital anomalies among the offspring.
- Conditions
- Gestational Diabetes, Pregestational Diabetes, IDM (Infant of Diabetic Mothers), Neurodevelopmental Outcome
- Trial name
- NCT01255384
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Atopy, Allergic Disease
Use Cord Blood Single Nucleotide Polymorphism to Predict the Later Development of Atopy and Allergy
The aim of our study was firstly to detect in cord bloods the polymorphism of genes related to atopy and allergic diseases and to examine their mutual interaction and their associations with cord blood IgE and cytokines.
- Trial name
- NCT00444327
- Where
- 2 sites in Taiwan
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Min-Sheng General Hospital
Vitamin D Deficiency, Vitamin D Insufficiency
Trial to Assess Vitamin D Requirements in Lactating Women
This is a randomized, placebo-controlled trial of vitamin D supplementation with 20mcg cholecalciferol (to achieve a total intake of 25mcg/day), with or without 500mg calcium to assess vitamin D requirements in lactating women…
- Trial name
- DMUMs (NCT01349127)
- Testing
- 20µg Vitamin D3, 20µg Vitamin D3 + 500 mg Calcium
- Where
- Ireland
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University College Cork
Pregnancy, Pregnancy in Diabetes
Exploration of the Lipid Metabolism During the Diabetic Pregnancies
Justification: Intrauterine exposure to type 1 or type 2 diabetes increase the risk of macrosomia (35 % to 50 % versus 10 % in general population) despite a good glycemic control.
- Conditions
- Pregnancy, Pregnancy in Diabetes, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
- Trial name
- DIAMANT (NCT00639964)
- Testing
- blood tests, diet questionnaire, umbilical cord blood collect
- Where
- France
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Gestatiaonl Diabetes Mellitus
Maternal and Cord Blood MST1 Levels in Gestational Diabetes Mellitus
In pregnancies with gestational diabetes (GDM), a protein called MST1 is significantly higher in both mothers and baby cord blood. This suggests MST1 plays a key role in the disease.
- Trial name
- MST1 Levels (NCT07878455)
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Samsun University