Clinical trials: Umbilical Cord Issue
Placenta Diseases, IVF
Ultrasound Diagnosis of Placental and Umbilical Cord Anomalies in Singleton Pregnancies Resulting From In-vitro Fertilization
Objectives: to identify which type of placental and umbilical cord abnormalities are more common in IVF singleton pregnancies; to investigate if heterologous fertilization is an additional risk factor for the development of these…
- Trial name
- PLACENTA (NCT05172674)
- Testing
- ultrasound according routine antenatal care
- Where
- Italy
- Volunteers
- 587 people, healthy volunteers welcome
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Umbilical Cord Issue, Intrauterine Growth Restriction
Three-dimensional Umbilical Cord Coiling Index
Previous studies have shown that abnormal coiling of the umbilical cord is associated with adverse perinatal outcome. For example, an umbilical cord that is non-coiled increases the chance of fetal morbidity and mortality…
- Conditions
- Umbilical Cord Issue, Intrauterine Growth Restriction, Fetal Distress
- Trial name
- NCT05727241
- Testing
- Ultrasound
- Where
- Israel
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Umbilical Cord Issue
The Use of Arnica Montana in the Cicatrization of the Umbilical Cord
Neonatal infections are still one of the leading causes of mortality among newborns worldwide. For example, omphalitis is particularly common and can lead to the development of neonatal sepsis.
- Trial name
- NCT05958251
- Testing
- Cicaben, Standard Care (in control arm)
- Where
- 2 sites in Italy
- Volunteers
- 326 people
- Sponsor
- Ospedale Buon Consiglio Fatebenefratelli
Umbilical Cord Issue, Mothers
The Effect of Umbilical Cord Care Training on Cord Falling Time
Under normal conditions, the umbilical cord is removed 5-15 days after birth. It dries up and falls within days. It is extremely important to determine the factors that cause the prolongation of the falling time of the cord…
- Conditions
- Umbilical Cord Issue, Mothers, Infant Conditions
- Trial name
- NCT05573737
- Testing
- education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Firat University
Near-Infrared Spectroscopy, Umbilical Cord Issue
"Improves Physiological Based Cord Clamping (PBCC) the Systemic and Cerebral Oxygenation in Term Infants?"
The first major intervention a newborn infant is facing following birth is clamping of the umbilical cord. This means separation of the infant from the placenta, the newborn becomes an independent individual, especially from a…
- Trial name
- NCT02763436
- Testing
- physiological-based cord clamping
- Where
- Austria
- Volunteers
- 78 people
- Sponsor
- Medical University of Graz
Inflammatory Markers, Preeclampsia Severe
Assessment of Maternal and Fetal Serum Biomarkers in Women With Pre-eclampsia
The findings of markers of placental dysfunction in women with preeclampsia may suggest that these biomarkers may be useful tools for early detection of preeclampsia
- Conditions
- Inflammatory Markers, Preeclampsia Severe, Preeclampsia Mild, Umbilical Cord Issue
- Trial name
- NCT06712550
- Where
- Iraq
- Volunteers
- 204 people
- Sponsor
- SHAHLA KAREEM ALALAF
Infant, Extremely Premature, Erythrocyte Transfusion
Red Blood Cells From Umbilical Cord for Transfusion of Preterm Infants
This study has been designed to demonstrate that red blood cell from umbilical cord blood (UCB-RBC) is a safe and available product for extremely preterm infants (EPI) transfusion and that transfusion of UCB-RBC is non-less…
- Conditions
- Infant, Extremely Premature, Erythrocyte Transfusion, Umbilical Cord Issue
- Trial name
- NCT05612919
- Testing
- Red blood cell from umbilical cord blood, Red blood cell from adult donor
- Where
- Spain
- Volunteers
- 41 people
- Sponsor
- Hospital Clinic of Barcelona
Newborn; Anemia, Umbilical Cord Problem
Supine vs Prone Position During Delayed Cord Clamping
This study is conducted to evaluate if the prone position of the newborn on the chest of his mother at birth before delayed cord clamping leads to better hematocrit and hemoglobin at 24-48 hours of life compared to supine…
- Trial name
- DCC (NCT03697967)
- Testing
- supine or prone position
- Where
- Canada
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Maisonneuve-Rosemont Hospital
Umbilical Cord Problem
Umbilical Cord Length Index for Prediction of Cord Abnormalities Before Delivery
The umbilical cord plays an essential role in intrauterine life. It is the pathway between mother, placenta and fetus during pregnancy and delivery.
- Trial name
- NCT03604887
- Testing
- ultrasonography
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Assiut University
Umbilical Cord Issue, Nicotine Addiction
Nicotine's Effect on Cancer Stem Cell Markers in Human Umbilical Cord Tissue
The umbilical cord is generally an organ that clinicians and pathologists do not pay sufficient attention to. The absence of significant pathology in the umbilical cords, along with the lack of association between certain…
- Conditions
- Umbilical Cord Issue, Nicotine Addiction, Pregnancy Related, Cancer
- Trial name
- NCT06678152
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Pregnancy Related, Umbilical Cord Issue
Association Between Blood Volume, the Interval From Delivery to Cord Clamping, and Number of Umbilical Cord Milking
Delayed umbilical cord clamping (DCC), usually 1-3 minutes, is reported to be beneficial for term and preterm infants. Nevertheless, there are reasons that urge us to reevaluate the effect of DCC.
- Conditions
- Pregnancy Related, Umbilical Cord Issue, Placental Transfusion
- Trial name
- NCT04898868
- Testing
- cord blood spontaneous drainage, Umbilical cord miking
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Small for Gestational Age at Delivery, Hypoxic-Ischemic Encephalopathy
Umbilical Cord Abnormalities in the Prediction of Adverse Pregnancy Outcomes
The objective of our study is to investigate the association of umbilical cord abnormalities with adverse pregnancy outcomes. The umbilical cord parameters that will be investigated as part of this study include the umbilical…
- Conditions
- Small for Gestational Age at Delivery, Hypoxic-Ischemic Encephalopathy, Stillbirth, Admission to Neonatal Unit
- Trial name
- ULOOP (NCT05901688)
- Testing
- Umbilical cord measurements & observations
- Where
- United Kingdom
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Medway NHS Foundation Trust