Clinical trials: Uncomplicated Pregnancy
Fetal Growth Restriction
Timing of Delivery in Fetal Growth Restriction of Uncomplicated Women
The goal of the study is to determine whether labor induction at 37 weeks of pregnancy can improve the baby's health at birth when compared with delivery at a later point in the pregnancy.
- Trial name
- GROW (NCT03046355)
- Testing
- Labor induction at 37.0 to 37.6 weeks of gestation, Expectant monitoring until delivery
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- The University of Texas Health Science Center, Houston
Urinary Tract Infection, Fever
Treatment's Duration of Acute Uncomplicated Pyelonephritis
The purpose of this study is to compare the efficacy of 5 days versus 10 days treatment duration in uncomplicated acute pyelonephritis.
- Trial name
- DTP (NCT00873626)
- Testing
- levofloxacin, ciprofloxacin and ofloxacin (fluoroquinolones)
- Where
- 2 sites in France
- Volunteers
- 310 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ureteral Calculi, Hyperalgic, Not Complicated
Nefopam and Morphine Consumption in the Treatment of Ureteral Calculi
The administration of néfopam after initial treatment by kétoproféne, could obtain, in patients remaining pain and classically need morphine, analgesia at least the same as morphine alone.
- Trial name
- NCT00639574
- Testing
- Néfopam
- Where
- France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Clermont-Ferrand
Malaria, Falciparum, Hookworm Infections
Iron Absorption and Utilization in Adolescents Infected With Malaria Parasites, Hookworms or Schistosoma
The aim of this study is to investigate the change in iron metabolism in relation to malaria and helminth infections using a stable isotope technique.
- Conditions
- Malaria, Falciparum, Hookworm Infections, Schistosoma Haematobium
- Trial name
- NCT01163877
- Testing
- Fe-57 orally, Fe-58 intravenously
- Where
- Côte d’Ivoire
- Volunteers
- 43 people
- Sponsor
- Swiss Federal Institute of Technology
Urinary Tract Infection in Pregnancy
Lactobacillus Reuteri for Treatment of Uncomplicated UTI in Pregnant Women
Prevalence of uro-genital infections during pregnancy move between 7% to 12% in developed countries, meanwhile in developing countries this figure moved between 14% and until 55%, such is the case of Mexico.
- Trial name
- UTIPregnant (NCT03362697)
- Testing
- Probiotics, Antibiotics
- Where
- Mexico
- Volunteers
- 150 people
- Sponsor
- Innovacion y Desarrollo de Estrategias en Salud
Recurrent Urinary Tract Infections in Women
Evaluate the Efficacy and Safety of U101 Oral Capsules in the Prevention of Uncomplicated rUTIs in Women
The goal of this clinical trial is to learn if drug U101 works to prevent recurrent urinary tract infection (rUTI) in women (≥ 20 and < 76 years old) with a medical history.
- Trial name
- U101 (NCT07184827)
- Testing
- U101
- Where
- 18 sites in Taiwan
- Volunteers
- 348 people
- Sponsor
- TCM Biotech International Corp.
Urinary Tract Infections
Point of Care Susceptibility Testing in Primary Care
The purpose of this study is to determine whether point-of-care susceptibility testing improve correct choice of antibiotics, clinical and microbiological outcome in patients with uncomplicated urinary tract infection in general…
- Trial name
- NCT02323087
- Testing
- FLEXICULT™ SSI-Urinary Kit, ID FlexicultTM
- Where
- Denmark
- Volunteers
- 377 people
- Sponsor
- University of Copenhagen
Urinary Tract Disease, Cystitis
Effect of Cranberry Extract on the Urinary System
In this study, we will try to emphasize the effects of using cranberry tablets, which is an alternative to antibiotic therapy, during uncomplicated urinary tract infections (only urinary tract, bladder and kidney infections did…
- Conditions
- Urinary Tract Disease, Cystitis, Antibiotic Reaction
- Trial name
- NCT05260554
- Testing
- Fosfomycin, Cranberry
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Kırklareli University
Urinary Tract Infection
Safety and Efficacy of PP4001 for the Treatment of Symptoms Associated With Uncomplicated Urinary Tract Infection
PP4001 is a medication not yet approved by the US FDA. This is a phase 2, multi-center, randomized, double-blind study of 3 doses of PP4001 versus placebo in the treatment of symptoms associated with uncomplicated urinary tract…
- Trial name
- NCT01406587
- Testing
- PP4001
- Where
- 25 sites in United States
- Volunteers
- 261 people
- Sponsor
- Pinnacle Pharmaceuticals, Inc.
Malaria
Quinine vs. Artemether/Lumefantrine in Uncomplicated Malaria During Pregnancy
A) for the treatment of uncomplicated malaria during second and third trimester pregnancy to oral Quinine hydrochloride. The PCR-corrected adequate clinical and parasitological response (ACPR) on day 42 is considered as the…
- Trial name
- NCT00495508
- Testing
- Quinine, artemether / lumefantrine
- Where
- Uganda
- Volunteers
- 300 people
- Sponsor
- Epicentre
Malaria
Comparison of Two Regimens of Artemether-lumefantrine for the Treatment of Malaria in Pregnancy
Malaria in pregnancy is a major cause of maternal and newborn morbidity and mortality in sub-Saharan Africa]. Effective antimalarial preventive and treatment regimens can significantly reduce malaria-related morbidity and…
- Trial name
- ALN5P (NCT01916954)
- Testing
- 3-day artemether-lumefantrine, 5-day artemether-lumefantrine
- Where
- Republic of the Congo
- Volunteers
- 96 people
- Sponsor
- University of Oxford
Urinary Tract Infection Chronic
Individualized Homeopathy to Reduce the Use of Antibiotics in Women With Recurrent Uncomplicated Urinary Tract Infections
The aim of the study is to determine the efficacy of individualised homeopathic drug treatment (potency C200 and C1000) compared to placebo in females (age 18<65) with recurrent urinary tract infections, per definition ≥ 2 UTI in…
- Trial name
- iHOM (NCT05545514)
- Testing
- One out of 140 predefined homeopathic medical products (HMP) in potency C200 or C1000,
- Where
- Germany
- Volunteers
- 220 people
- Sponsor
- Technical University of Munich
Urinary Tract Infections
A Study of LBP-EC01 in the Treatment of Acute Uncomplicated UTI Caused by Drug Resistant E. Coli (ELIMINATE Trial)
This is a Phase 2 superiority study of LBP-EC01, a recombinant bacteriophage cocktail, with an initial open-label 3-arm pharmacokinetic (PK) lead-in portion of 30 patients to evaluate the optimal dosing regimen to be used in the…
- Trial name
- ELIMINATE (NCT05488340)
- Testing
- LBP-EC01 0.1 x IV dose, LBP-EC01 0.01x IV Dose, LBP-EC01 IV Infusion Dose
- Where
- 17 sites in United States
- Volunteers
- 318 people
- Sponsor
- Locus Biosciences
Pregnancy Complicated by Malaria as Antepartum Condition
Efficacy,Safety and Tolerability of Dihydroartemisinin-Piperaquine for Uncomplicated Malaria in Pregnancy in Ghana
Malaria in pregnancy poses enormous public health challenges, contributing to significant maternal and infant deaths yearly. Adverse outcomes include maternal anaemia and low birthweight.
- Trial name
- DHAPPQ/MIP (NCT01231113)
- Testing
- artesunate-amodiaquine, Dihydroartemisinin-piperaquine
- Where
- Ghana
- Volunteers
- 417 people
- Sponsor
- Kwame Nkrumah University of Science and Technology
Acute Uncomplicated Bacterial Cystitis
Epidemiology of Acute Bacterial Uncomplicated Cystitis in General Practice
Acute uncomplicated bacterial cystitis is common in general practice. Cystitis is at the second raw of antibiotic treatment indications.
- Trial name
- BaCyst (NCT00958295)
- Where
- France
- Volunteers
- 362 people
- Sponsor
- University Hospital, Rouen
Urinary Tract Infections
Symptomatic Therapy of Uncomplicated Lower Urinary Tract Infections in the Ambulatory Setting.
We propose to perform a randomized controlled patient and assessor blind trial in women between the ages of 18 to 70 years with acute uncomplicated UTI to evaluate initial symptomatic treatment for 3 days with the non-steroidal…
- Trial name
- NCT01039545
- Testing
- Diclofenac, Norfloxacin
- Where
- Switzerland
- Volunteers
- 253 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Malaria
Efficacy of Artemisinin Combination Therapies for the Treatment of Uncomplicated P. Falciparum in Pregnancy in Brazil
Data on the burden of MIP in low transmission areas, such as Latin America, are very limited; there is even less information on the efficacy of case management of MiP.
- Trial name
- PAACT-PF (NCT01082731)
- Testing
- Artemether-Lumefantrine, Mefloquine- Artesunate
- Where
- 2 sites in Brazil
- Volunteers
- 6 people
- Sponsor
- Centers for Disease Control and Prevention
Respiratory Syncytial Virus Infections
A Study of Safety, Reactogenicity and Immune Response of the Repeat Vaccination Against RSV When Given to Female Participants of 18-49 Years of Age During Their Subsequent Uncomplicated Pregnancy
The purpose of this study is to evaluate the safety, reactogenicity and immunogenicity of a single intramuscular dose of the investigational respiratory syncytial virus (RSV) maternal (RSV MAT) vaccine during subsequent…
- Trial name
- NCT05229068
- Testing
- RSV MAT
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Urinary Tract Infection
Immediate vs. Conditional Use of Antibiotics in Uncomplicated Urinary Tract Infection (UTI) - ICUTI
In this study, patients with uncomplicated urinary infection are investigated. It is investigated if treatment of only symptoms of the uncomplicated urinary infection is as effective as treatment with antibiotics with respect to…
- Trial name
- NCT01488955
- Testing
- Ibuprofen, Fosfomycin-Trometamol
- Where
- 2 sites in Germany
- Volunteers
- 494 people
- Sponsor
- Institut fuer anwendungsorientierte Forschung und klinische Studien GmbH
Unilateral Ureteral Stone, Renal Stone Fragments ≤ 2mm
Feasibility Study of the Uriprene Stent Following Uncomplicated Ureteroscopy
A prospective, single-center, single-arm, trial to demonstrate safety and device performance of the ADVA-Tec Uriprene™ Degradable Temporary Ureteral Stent. This is a first-in-man clinical study in a small human population.
- Trial name
- URIPRENE (NCT02032316)
- Testing
- Post-Ureteroscopy ADVA-Tec Uriprene™ Degradable Temporary Ureteral Stent
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Adva-Tec