Clinical trials: Unilateral
Burn Injury
Evaluation of Gait Symmetry in Upper Extremity Burn Injuries
Thirty patients with unilateral burn injury, and 60 healthy subjects will be included in this study. Participants with burn injury will evaluate with the following assessment tools: Demographic data; age, gender, height, body…
- Trial name
- NCT03759613
- Testing
- Gait Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Sudden Sensorineural Hearing Loss
Speech Perception Impairment Follow Complete Recovery of Sudden Sensorineural Hearing Loss
At present, few research on the auditory perception function and possible neural mechanisms of unilateral sudden hearing loss patients with complete or partial recovery of peripheral hearing.This project evaluate the speech…
- Trial name
- NCT05608161
- Testing
- speech in noise test
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Follicular Thyroid Cancer, SEER Database Analysis
Long-term Survival Outcomes of Total Thyroidectomy and Radioactive Iodine Therapy in Unilateral T3/T4 FTC
This study aims to thoroughly examine survival disparities in patients with T3 or T4 stage follicular thyroid carcinoma (FTC) as classified by the AJCC staging system.
- Trial name
- NCT06437873
- Testing
- Total Thyroidectomy (TT), Radioactive iodine treatment(RAIT)
- Volunteers
- 2,957 people, healthy volunteers welcome
- Sponsor
- Dezhou Hospital Qilu Hospital of Shandong University
Low Back Pain
The Impact of Unilateral Lower Limb Amputation on Spinal Loads
The prevalence of low back pain among persons with unilateral lower limb amputation is significantly higher than the rate experienced by the general public.
- Trial name
- NCT02897973
- Testing
- Activity of daily living
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- University of Kentucky
Hearing Loss
Use of Functional Near-infrared Spectroscopy to Investigate Role of Human Auditory Cortex Plasticity and Multi-sensory Integration on Cochlear Implant Performance After Single-sided Deafness
The timing of brain changes that may influence hearing rehabilitation within human A1 after single-sided deafness (SSD) is not known. The goal is to determine when A1 neural plasticity occurs following SSD onset.
- Trial name
- NCT03713554
- Testing
- FNIRS Observational
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Michigan
Peripheral Nerve Injuries
Pain-related Evoked Potentials in Unilateral Peripheral Nerve Injuries
The study examines pain-related evoked potentials (PREP) in patients with peripheral nerve injuries. Since previous studies found altered latencies and amplitudes of PREP in generalized polyneuropathies, e. g.
- Trial name
- NCT03082820
- Testing
- Pain-related evoked potentials (PREP), Quantitative Sensory Testing (QST), Nerve conduction studies (NCS)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Lower Limb Amputation Above Knee (Injury)
The CYBERnetic Lower Limb Cocognitive Ortho-prosthesis Plus Plus, 1st Clinical Study (CLs++)
The aim of the study is to assess the efficacy and the usability of the cyberlegs ++ ortho prosthesis to improve the mobility and the quality of life in transfemoral amputees .
- Trial name
- NCT03376919
- Testing
- CLs++ gait training
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Renal Colic, Acute Renal Failure
Urinary Markers for Unilateral Kidney Obstruction
Renal colic is usually caused from an obstructing stone along the ureter. Some of the patients present with a high level of creatinin in the blood, even though there is a normal functioning contralateral kidney.
- Trial name
- NCT01979042
- Where
- Israel
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Healthy
Serum Metal Ion Concentrations Following Primary Hip Arthroplasty
The objective of this study is to compare serum chromium and cobalt levels of patients who have undergone metal on metal total hip arthroplasty.
- Trial name
- NCT00714610
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Utah
Cleft Lip and Palate
Assessment of Maxillary Arch Depth and Width in a Group of Surgically Repaired Unilateral Cleft Lip and Palate Children Versus Normal Children .
The aim of the present study is to determine the effect of surgically repaired UCLP on dental arch dimensions and the need for orthodontic intervention in comparison with other healthy children , the presence of dental anomalies…
- Trial name
- NCT04791813
- Testing
- Alginate impressions , Photographic data and panoramic radiographs .
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ankle Injuries, Ankle Sprains
The Effects of Unilateral Balance Training Among Athletes With Chronic Ankle Instability
The aim of the study is to investigate the effects of a 4-week, unilateral balance exercise training program on bilateral balance and explosive power in athletes with chronic ankle instability.
- Trial name
- NCT04139044
- Testing
- Balance Exercise Training for Stable Ankle, Balance Exercise Training for Unstable Ankle
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Osteoporosis, Excitability
Effects Of Unilateral Vibration On Contralateral Forearm Muscle Activity
This study hypothesize that radius subjecting to mechanical loading may affect excitability of alpha motor neuron innervating muscle, based on its bone mineral density or bone mineral content.
- Trial name
- BMRR3 (NCT01097122)
- Testing
- Forearm vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Vakif Gureba Training and Research Hospital
Muscle Weakness
Effects of a Thoracic Manipulation on Hip Adductor, Extensor, and Latissimus Dorsi Force in Those With Adductor Weakness
The goal of this trial was to determine if a mid-thoracic high velocity low amplitude spinal manipulation improves force output in those with unilateral hip adductor weakness.
- Trial name
- NCT06534931
- Testing
- High velocity low amplitude thoracic spine manipulation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of New England
Postoperative Pain
Phase 2 Bunionectomy HTX-011 Administration Study
This is a Phase 2, open-label, multi-cohort study to evaluate the analgesic efficacy, safety, and pharmacokinetics (PK) of a single, individualized dose of HTX-011 administered into the surgical site as a monotherapy or with…
- Trial name
- NCT03718039
- Testing
- HTX-011, Luer Lock applicator, Vial access device
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Heron Therapeutics
Healthy, Muscle Disuse Atrophy
The Effects of Protein Supplementation With or Without Urolithin A During Single-leg Immobilization
There are times in life when people cannot use their muscles, such as during illness or injury. Muscle and mitochondria (the 'energy factory' in cells) health decline very quickly when people cannot use their muscles, but certain…
- Trial name
- NCT05814705
- Testing
- Protein supplement, Protein supplement with Urolithin A
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- McMaster University
Unilateral Cerebral Palsy
Validation of AI for Personalized Assessment and Rehabilitation of Upper Limb in Children With Unilateral Cerebral Palsy
Unilateral Cerebral palsy (UCP) is the most common neurological chronic disease in childhood with a significant burden on children, their families and health care system.
- Trial name
- AInCP (NCT06073522)
- Testing
- Artificial Intelligence for combining multi-domain data acquisition
- Where
- 2 sites in Italy, Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- IRCCS Fondazione Stella Maris
Healthy Volunteers
To studyJUV-161 Administered to Healthy Volunteers Undergoing Unilateral Lower Limb Immobilization (ULLI)
This is a double-blind, placebo-controlled, randomized study of 96 days total duration to assess the effect of JUV-161 on muscle disuse atrophy.
- Trial name
- NCT07397468
- Testing
- JUV-161
- Where
- 2 sites in New Zealand
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Juvena Therapeutics
Amputees
Physical Activity in Adults With Amputation
This cross-sectional study explores physical activity and energy expenditure among inactive adults with a unilateral transtibial amputation.
- Trial name
- NCT03722797
- Testing
- Metabolic Cost Testing Procedures
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Anesthesia, Local
Optimal Volume of Bupivacaine in Adductor Canal Nerve Block
To establish adequate volume of levobupivacaine 0.25% in adductor canal nerve block in unilateral cruciate ligament of the knee reconstruction surgery.
- Trial name
- NCT02557386
- Testing
- Levobupivacaine 5 mL, Levobupivacaine 10 mL, Levobupivacaine 15 mL
- Where
- Chile
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Cleft Lip and Palate, Unilateral Cleft Lip
Influence of Presurgical Orthodontic Molding on the Growth of Newborns With Unilateral Cleft Lip Palate
Orofacial clefts are the second most common birth deformity and vary in etiology and phenotype, e.g. isolated cleft palate, cleft lip or cleft lip palate.
- Trial name
- NCT05081258
- Testing
- passive Alveolar Molding, Nasoalveolar Molding
- Where
- Germany
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg